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The map label for this gene is rna [C]

Identifier: 158424762

GI number: 158424762

Start: 3594016

End: 3594654

Strand: Direct

Name: rna [C]

Synonym: AZC_3138

Alternate gene names: 158424762

Gene position: 3594016-3594654 (Clockwise)

Preceding gene: 158424761

Following gene: 158424763

Centisome position: 66.93

GC content: 68.54

Gene sequence:

>639_bases
GTGAGGCTTCTCGCCGGCTTGCTGCTGCTTCTGGCGACGGCAACCGGCGCGTTCGCCGCCGAGGATAGACCGGGCGCGTT
CGATTTCTACGTTCTCTCCCTCTCCTGGTCGCCCAGCTATTGCGCCACGCGCGACAGGCCGGACGGCCTGCAATGCGGCG
GCCCCCGCCCCTTCGCCTTCGTCGTGCACGGCCTGTGGCCGCAGTATGAGAAAGGCTATCCGCAGGATTGCGATCGCTCG
GCGCCGCGCCTGCCCCAGCGCCAGATCGACGGCATGCTCGACCTGATGCCGAGCCCCGGCCTCGTCATCCATGAGTGGCG
CAAGCACGGCACCTGCTCGGGCCTTTCGGCGACCGCCTATTTCGACCTCGTGCGCAGCGCCCGCGCCAAGGTTGAGATCC
CGCCGTCCTATGTAAACCCGACGGACTATCGCATGGTCTCGCCGGCCGAGGTGGAGACCGCCTTCATCGCCGCCAATCCG
GGCCTAGAGGCCAACATGCTGTCGGTGGACTGCGACAAGACGCGGCTGCGCGAAGTGCGCATCTGCCTCTCCAAGTCGCT
CACCTTCCGCCCCTGCCCCGAGGTGGACGCCAAGAGCTGCCCCGCCGGCCGGCGCCTCGCCGTTCCCCCCTTGCGCTGA

Upstream 100 bases:

>100_bases
AGGATGGCGGCTGGCAGAACATGACCTGGGGCGTCGAGTGGTGCATCCCGGAGTATGACCGGGAATTCGCCTACGCGCCC
AAGTGCACCATGGCCCGTCC

Downstream 100 bases:

>100_bases
GGCCGTCTTCCGGCGAAGACGCGGCATGAACTATCGCCACGCCTTCCACGCCGGAAACCCGGCGGATGTCATGAAGCATG
CGACCCTCGCCCGCGTGCTC

Product: ribonuclease T2 precursor

Products: 3'- Phosphomononucleotides; 3'-Phosphooligonucleotides [C]

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MRLLAGLLLLLATATGAFAAEDRPGAFDFYVLSLSWSPSYCATRDRPDGLQCGGPRPFAFVVHGLWPQYEKGYPQDCDRS
APRLPQRQIDGMLDLMPSPGLVIHEWRKHGTCSGLSATAYFDLVRSARAKVEIPPSYVNPTDYRMVSPAEVETAFIAANP
GLEANMLSVDCDKTRLREVRICLSKSLTFRPCPEVDAKSCPAGRRLAVPPLR

Sequences:

>Translated_212_residues
MRLLAGLLLLLATATGAFAAEDRPGAFDFYVLSLSWSPSYCATRDRPDGLQCGGPRPFAFVVHGLWPQYEKGYPQDCDRS
APRLPQRQIDGMLDLMPSPGLVIHEWRKHGTCSGLSATAYFDLVRSARAKVEIPPSYVNPTDYRMVSPAEVETAFIAANP
GLEANMLSVDCDKTRLREVRICLSKSLTFRPCPEVDAKSCPAGRRLAVPPLR
>Mature_212_residues
MRLLAGLLLLLATATGAFAAEDRPGAFDFYVLSLSWSPSYCATRDRPDGLQCGGPRPFAFVVHGLWPQYEKGYPQDCDRS
APRLPQRQIDGMLDLMPSPGLVIHEWRKHGTCSGLSATAYFDLVRSARAKVEIPPSYVNPTDYRMVSPAEVETAFIAANP
GLEANMLSVDCDKTRLREVRICLSKSLTFRPCPEVDAKSCPAGRRLAVPPLR

Specific function: One of the few RNases that cleave the phosphodiester bond between any two nucleotide. Shows a preference for adenylic acid [H]

COG id: COG3719

COG function: function code J; Ribonuclease I

Gene ontology:

Cell location: Periplasm. Cytoplasm. Note=An RNase I-like form (periplasmic) and RNase I*-like form (cytoplasmic) appear to be isoforms apparently encoded by the same gene. The cytoplasmic form is less active towards natural polymer RNA [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase T2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001568
- InterPro:   IPR018188 [H]

Pfam domain/function: PF00445 Ribonuclease_T2 [H]

EC number: 3.1.27.6 [C]

Molecular weight: Translated: 23355; Mature: 23355

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00530 RNASE_T2_1 ; PS00531 RNASE_T2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLAGLLLLLATATGAFAAEDRPGAFDFYVLSLSWSPSYCATRDRPDGLQCGGPRPFAF
CHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEE
VVHGLWPQYEKGYPQDCDRSAPRLPQRQIDGMLDLMPSPGLVIHEWRKHGTCSGLSATAY
EEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEHHHCCCCCCCCHHHHH
FDLVRSARAKVEIPPSYVNPTDYRMVSPAEVETAFIAANPGLEANMLSVDCDKTRLREVR
HHHHHHCCCEEECCCCCCCCCCCEEECCCCCEEEEEEECCCCCCEEEEECCCHHHHHHHH
ICLSKSLTFRPCPEVDAKSCPAGRRLAVPPLR
HHHHCCCCCCCCCCCCCCCCCCCCEECCCCCC
>Mature Secondary Structure
MRLLAGLLLLLATATGAFAAEDRPGAFDFYVLSLSWSPSYCATRDRPDGLQCGGPRPFAF
CHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEE
VVHGLWPQYEKGYPQDCDRSAPRLPQRQIDGMLDLMPSPGLVIHEWRKHGTCSGLSATAY
EEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEHHHCCCCCCCCHHHHH
FDLVRSARAKVEIPPSYVNPTDYRMVSPAEVETAFIAANPGLEANMLSVDCDKTRLREVR
HHHHHHCCCEEECCCCCCCCCCCEEECCCCCEEEEEEECCCCCCEEEEECCCHHHHHHHH
ICLSKSLTFRPCPEVDAKSCPAGRRLAVPPLR
HHHHCCCCCCCCCCCCCCCCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Nucleotides [C]

Specific reaction: Endonucleolytic Cleavage With 2',3'-Cyclic Phosphate Intermediates. [C]

General reaction: Phosphoric ester hydrolysis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685334 [H]