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The map label for this gene is luxR [H]

Identifier: 158424719

GI number: 158424719

Start: 3541812

End: 3542576

Strand: Direct

Name: luxR [H]

Synonym: AZC_3095

Alternate gene names: 158424719

Gene position: 3541812-3542576 (Clockwise)

Preceding gene: 158424718

Following gene: 158424723

Centisome position: 65.96

GC content: 70.85

Gene sequence:

>765_bases
ATGACGCCTGTTCCCCCTTCACGCGCCGACCGCTCTTCGCCGGGCGAGGTTCTGCGCGCCGGTCCGCTGGAGATCCATGC
CACCGCGCGGCAGGCCTTCGTCAACGGCGCGCGCATCACCCTCGGCAGCCGGGCGTTCGACCTTCTGCTGATGCTCGCGG
AGGCCGCGGGCCGGGTGGTGTCCCACGACGAGATCCAGGCCCGGGTGTGGCCGAACCGGCATGTGAGCGAGACCAATCTG
CGGGTGCAGGTTTCAACGCTCCGGCGGGCGCTGGGCGAGGCCCGCCACGTCGTCAGCACCGTGCCGGACCGGGGCTACGC
CTTCACCCCCTTCGGCCAGCACGCGCCGGAGCCGGACGACGCCCCCGTGCCGGGCGATCATGTGGTGCATGTGGTGGACG
ACGAGGCGGACATGCGCGACGCCCTCGAAGGGCTGCTGATGGCGTCCGGCTGGCGGGTGCGCACCTACGGATCGGTGGGT
GCCTTCCAGGAAGCTCTGACGGCCCAGACCGCCGGCTGCCTGATCCTCGACGTCAGCCTGCCGGGCGAGAATGGCCTCGA
ACTCCAGCGCCGGCTGCTCGCCCTTGGCCTCAGCCTGCCCATCGTGTTCCTGAGCGGGCGGTCCAACATTCCCATCGCCG
TGGAAGCCATGAAGGCGGGGGCAATCGAATTCCTCACCAAGCCCGCCGCCGGCGAGGACATTCTCGCCGCGGTCGCGCGG
GCCATGGCACTGGCCCTGTCGGAACGCCCCCAGAGCCCTGCTTGA

Upstream 100 bases:

>100_bases
TGCTGACCAGCGTCATGCAGGCGCTTGCAAAGGGTTTTGACGGGACGCAATGATGCCGCTTCGGCATGATCATTCCGAGC
GGCCATAGCGCACCGCAGCC

Downstream 100 bases:

>100_bases
GGGGGCAACCGTCCTAATTGACGTGCGCGCGCTTCCACTGGCCCGGCGGCAGGCCGGTGTGGGCGCGGAAGACCCGCGTG
AAATGGCTCTGGTCCGCGAA

Product: DNA-binding response regulator

Products: NADP; 2 glutathione [C]

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTPVPPSRADRSSPGEVLRAGPLEIHATARQAFVNGARITLGSRAFDLLLMLAEAAGRVVSHDEIQARVWPNRHVSETNL
RVQVSTLRRALGEARHVVSTVPDRGYAFTPFGQHAPEPDDAPVPGDHVVHVVDDEADMRDALEGLLMASGWRVRTYGSVG
AFQEALTAQTAGCLILDVSLPGENGLELQRRLLALGLSLPIVFLSGRSNIPIAVEAMKAGAIEFLTKPAAGEDILAAVAR
AMALALSERPQSPA

Sequences:

>Translated_254_residues
MTPVPPSRADRSSPGEVLRAGPLEIHATARQAFVNGARITLGSRAFDLLLMLAEAAGRVVSHDEIQARVWPNRHVSETNL
RVQVSTLRRALGEARHVVSTVPDRGYAFTPFGQHAPEPDDAPVPGDHVVHVVDDEADMRDALEGLLMASGWRVRTYGSVG
AFQEALTAQTAGCLILDVSLPGENGLELQRRLLALGLSLPIVFLSGRSNIPIAVEAMKAGAIEFLTKPAAGEDILAAVAR
AMALALSERPQSPA
>Mature_253_residues
TPVPPSRADRSSPGEVLRAGPLEIHATARQAFVNGARITLGSRAFDLLLMLAEAAGRVVSHDEIQARVWPNRHVSETNLR
VQVSTLRRALGEARHVVSTVPDRGYAFTPFGQHAPEPDDAPVPGDHVVHVVDDEADMRDALEGLLMASGWRVRTYGSVGA
FQEALTAQTAGCLILDVSLPGENGLELQRRLLALGLSLPIVFLSGRSNIPIAVEAMKAGAIEFLTKPAAGEDILAAVARA
MALALSERPQSPA

Specific function: FixJ, when activated by fixL, induces the expression of both nifA, required for activation of classical nif and fix genes, and fixK, required for fixN activation [H]

COG id: COG4566

COG function: function code T; Response regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790299, Length=116, Percent_Identity=31.8965517241379, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789809, Length=129, Percent_Identity=27.1317829457364, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 27052; Mature: 26921

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPVPPSRADRSSPGEVLRAGPLEIHATARQAFVNGARITLGSRAFDLLLMLAEAAGRVV
CCCCCCCCCCCCCCCHHEECCCEEEEHHHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCC
SHDEIQARVWPNRHVSETNLRVQVSTLRRALGEARHVVSTVPDRGYAFTPFGQHAPEPDD
CCCCEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCC
APVPGDHVVHVVDDEADMRDALEGLLMASGWRVRTYGSVGAFQEALTAQTAGCLILDVSL
CCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCEEEEEEEC
PGENGLELQRRLLALGLSLPIVFLSGRSNIPIAVEAMKAGAIEFLTKPAAGEDILAAVAR
CCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEHHCCHHHHHCCCCCCHHHHHHHHH
AMALALSERPQSPA
HHHHHHHCCCCCCC
>Mature Secondary Structure 
TPVPPSRADRSSPGEVLRAGPLEIHATARQAFVNGARITLGSRAFDLLLMLAEAAGRVV
CCCCCCCCCCCCCCHHEECCCEEEEHHHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCC
SHDEIQARVWPNRHVSETNLRVQVSTLRRALGEARHVVSTVPDRGYAFTPFGQHAPEPDD
CCCCEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCC
APVPGDHVVHVVDDEADMRDALEGLLMASGWRVRTYGSVGAFQEALTAQTAGCLILDVSL
CCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCEEEEEEEC
PGENGLELQRRLLALGLSLPIVFLSGRSNIPIAVEAMKAGAIEFLTKPAAGEDILAAVAR
CCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEHHCCHHHHHCCCCCCHHHHHHHHH
AMALALSERPQSPA
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH2; oxidized glutathione [C]

Specific reaction: NADPH2 + oxidized glutathione = NADP + 2 glutathione [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a disulfide as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2000090; 12597275 [H]