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The map label for this gene is sdaA [H]

Identifier: 158424674

GI number: 158424674

Start: 3485900

End: 3487252

Strand: Direct

Name: sdaA [H]

Synonym: AZC_3050

Alternate gene names: 158424674

Gene position: 3485900-3487252 (Clockwise)

Preceding gene: 158424672

Following gene: 158424675

Centisome position: 64.92

GC content: 69.18

Gene sequence:

>1353_bases
ATGATCAGCGTGTTCGATCTCTTCAAGATCGGTGTGGGTCCCTCCTCCTCTCACACCGTCGGCCCCATGGTGGCGGCCAA
GCGCTTCCGGGACGAACTGCCGGTGGGCACCGCCCATGTCACGGCCGAGATCTTCGGCTCCCTGGCCTGGACCGGGAAGG
GCCACGCAACGGACCGGGCGCTATGCCTCGGCCTCATCGGCGCCGTGCCGGCGACGCTGGAGCCCGACGACGTGCCCGCC
CTCATCGCCCGCCTCGCCATCGAGAAGGCCATCGAGACGCCGGACGGTGGCCGGGCGACCTTCGATCCGGACGCCGACCT
CATCTTCGATTTCAAGACCCTGCTGCCGCGCCACACCAATGCGATGCGCTTTCGCGCCTATGATGGCGCAGGCGCTCTGA
CGCAGGAGCGCATCTTCTATTCGGTCGGCGGCGGCTTCGTGGTGGAGGACGGGGAGAACGAGGCGCCCCTCGGCACCGCG
CAGGTGCCCTACCCGTTTGACTGCGCCGCCGACATGCTCACCGTCTGCGCCCGCACGGGCCTCGACGTCGCGGGCGTGCA
GATGGCCAATGAATGCGCGCTCAGGTCCCGCGCCGAGGTGGAAGGCGGCCTCGATGCCATTGCGGACGCGATGTTCGGCT
GCATCGAGCGCGGCCTCTCCATGGATGGCAGCCTCCCCGGCCGGTTGCGGGTGAAGCGCCGGGCGAAAGCCATCCGGGAG
AAGCTGGAGGCCGACCGGGGCCTCAACCAGCGCCCGCCGCACGAGATCATGGACTGGGTGTCGGTCTTCGCCATCGCCGT
GAACGAGGAGAATGCGGCCGGCGGCCGGGTGGTAACCGCCCCCACCAATGGCGCGGCGGGCATCGTGCCGGCGGTGCTGC
GCTATGCCCGCGATTTCTGCCCCGATGTGGGCCCCGAGCAGGTGCGCTGCTTCCTGCTGACAGCGGCGGCGGTGGGCGGG
CTCATCAAGCGCAACGCCTCCATCTCGGGCGCGGAAGTGGGTTGCCAGGGCGAGGTGGGCTCCGCTGCCTCCATGGCTGC
CGCCGGCCTTGCGGCGGTGCTGGGGGCCAGTCCCGAGCAGATCGAGAATGCCGCCGAGATCGCCATGGAGCACCACCTCG
GCATGACATGCGACCCCATCGGCGGCCTGGTTCAGATCCCCTGCATCGAGCGCAACGCCTTCGGCGCCAACAAGGCCATC
GCCGCAGCCTCGCTGGCGCTGCGGGGTGACGGCATCCACAACGTGTCGCTGGATCAGGTGATCGAGACCATGCGCCAGAC
CGGCGCGGACATGCAGTCCAAATACAAGGAGACCTCCCAGGGAGGCCTCGCCGTGAACGTGCCCGAGTGCTGA

Upstream 100 bases:

>100_bases
CCGGCTTCTGGTGGAGGCGCGCACCGCCTGCCCTATGGCTGCCCGGTTCGCCCCGCTTAAACCGTGTGCGGCCCTGCAGA
ATGAAGGAGAGGTCGAAGAA

Downstream 100 bases:

>100_bases
GGCGGCACGCCGCCTGATTTTTCCATCTTCACGAGACCGACGCGCCGGCCCTCCGGCGTGAACGATGTGCCATGCCTTCC
AGAAGAAGAGGACGCCCCAT

Product: L-serine dehydratase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MISVFDLFKIGVGPSSSHTVGPMVAAKRFRDELPVGTAHVTAEIFGSLAWTGKGHATDRALCLGLIGAVPATLEPDDVPA
LIARLAIEKAIETPDGGRATFDPDADLIFDFKTLLPRHTNAMRFRAYDGAGALTQERIFYSVGGGFVVEDGENEAPLGTA
QVPYPFDCAADMLTVCARTGLDVAGVQMANECALRSRAEVEGGLDAIADAMFGCIERGLSMDGSLPGRLRVKRRAKAIRE
KLEADRGLNQRPPHEIMDWVSVFAIAVNEENAAGGRVVTAPTNGAAGIVPAVLRYARDFCPDVGPEQVRCFLLTAAAVGG
LIKRNASISGAEVGCQGEVGSAASMAAAGLAAVLGASPEQIENAAEIAMEHHLGMTCDPIGGLVQIPCIERNAFGANKAI
AAASLALRGDGIHNVSLDQVIETMRQTGADMQSKYKETSQGGLAVNVPEC

Sequences:

>Translated_450_residues
MISVFDLFKIGVGPSSSHTVGPMVAAKRFRDELPVGTAHVTAEIFGSLAWTGKGHATDRALCLGLIGAVPATLEPDDVPA
LIARLAIEKAIETPDGGRATFDPDADLIFDFKTLLPRHTNAMRFRAYDGAGALTQERIFYSVGGGFVVEDGENEAPLGTA
QVPYPFDCAADMLTVCARTGLDVAGVQMANECALRSRAEVEGGLDAIADAMFGCIERGLSMDGSLPGRLRVKRRAKAIRE
KLEADRGLNQRPPHEIMDWVSVFAIAVNEENAAGGRVVTAPTNGAAGIVPAVLRYARDFCPDVGPEQVRCFLLTAAAVGG
LIKRNASISGAEVGCQGEVGSAASMAAAGLAAVLGASPEQIENAAEIAMEHHLGMTCDPIGGLVQIPCIERNAFGANKAI
AAASLALRGDGIHNVSLDQVIETMRQTGADMQSKYKETSQGGLAVNVPEC
>Mature_450_residues
MISVFDLFKIGVGPSSSHTVGPMVAAKRFRDELPVGTAHVTAEIFGSLAWTGKGHATDRALCLGLIGAVPATLEPDDVPA
LIARLAIEKAIETPDGGRATFDPDADLIFDFKTLLPRHTNAMRFRAYDGAGALTQERIFYSVGGGFVVEDGENEAPLGTA
QVPYPFDCAADMLTVCARTGLDVAGVQMANECALRSRAEVEGGLDAIADAMFGCIERGLSMDGSLPGRLRVKRRAKAIRE
KLEADRGLNQRPPHEIMDWVSVFAIAVNEENAAGGRVVTAPTNGAAGIVPAVLRYARDFCPDVGPEQVRCFLLTAAAVGG
LIKRNASISGAEVGCQGEVGSAASMAAAGLAAVLGASPEQIENAAEIAMEHHLGMTCDPIGGLVQIPCIERNAFGANKAI
AAASLALRGDGIHNVSLDQVIETMRQTGADMQSKYKETSQGGLAVNVPEC

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=457, Percent_Identity=50.7658643326039, Blast_Score=435, Evalue=1e-123,
Organism=Escherichia coli, GI1789161, Length=460, Percent_Identity=50.6521739130435, Blast_Score=432, Evalue=1e-122,
Organism=Escherichia coli, GI1788116, Length=456, Percent_Identity=51.0964912280702, Blast_Score=430, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 47067; Mature: 47067

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVFDLFKIGVGPSSSHTVGPMVAAKRFRDELPVGTAHVTAEIFGSLAWTGKGHATDRA
CCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCCCCCHHH
LCLGLIGAVPATLEPDDVPALIARLAIEKAIETPDGGRATFDPDADLIFDFKTLLPRHTN
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
AMRFRAYDGAGALTQERIFYSVGGGFVVEDGENEAPLGTAQVPYPFDCAADMLTVCARTG
CEEEEEECCCCCCHHHHEEEEECCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
LDVAGVQMANECALRSRAEVEGGLDAIADAMFGCIERGLSMDGSLPGRLRVKRRAKAIRE
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
KLEADRGLNQRPPHEIMDWVSVFAIAVNEENAAGGRVVTAPTNGAAGIVPAVLRYARDFC
HHHHHCCCCCCCCHHHHHHHHHHHEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHC
PDVGPEQVRCFLLTAAAVGGLIKRNASISGAEVGCQGEVGSAASMAAAGLAAVLGASPEQ
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHH
IENAAEIAMEHHLGMTCDPIGGLVQIPCIERNAFGANKAIAAASLALRGDGIHNVSLDQV
HHHHHHHHHHHHCCCCCCCCCCEEECCEECCCCCCCCHHHHHHHHEEECCCCCCCCHHHH
IETMRQTGADMQSKYKETSQGGLAVNVPEC
HHHHHHCCCHHHHHHHHHCCCCEEEECCCC
>Mature Secondary Structure
MISVFDLFKIGVGPSSSHTVGPMVAAKRFRDELPVGTAHVTAEIFGSLAWTGKGHATDRA
CCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCCCCCHHH
LCLGLIGAVPATLEPDDVPALIARLAIEKAIETPDGGRATFDPDADLIFDFKTLLPRHTN
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
AMRFRAYDGAGALTQERIFYSVGGGFVVEDGENEAPLGTAQVPYPFDCAADMLTVCARTG
CEEEEEECCCCCCHHHHEEEEECCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
LDVAGVQMANECALRSRAEVEGGLDAIADAMFGCIERGLSMDGSLPGRLRVKRRAKAIRE
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
KLEADRGLNQRPPHEIMDWVSVFAIAVNEENAAGGRVVTAPTNGAAGIVPAVLRYARDFC
HHHHHCCCCCCCCHHHHHHHHHHHEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHC
PDVGPEQVRCFLLTAAAVGGLIKRNASISGAEVGCQGEVGSAASMAAAGLAAVLGASPEQ
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHH
IENAAEIAMEHHLGMTCDPIGGLVQIPCIERNAFGANKAIAAASLALRGDGIHNVSLDQV
HHHHHHHHHHHHCCCCCCCCCCEEECCEECCCCCCCCHHHHHHHHEEECCCCCCCCHHHH
IETMRQTGADMQSKYKETSQGGLAVNVPEC
HHHHHHCCCHHHHHHHHHCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]