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The map label for this gene is yafE [C]

Identifier: 158424651

GI number: 158424651

Start: 3460441

End: 3461259

Strand: Direct

Name: yafE [C]

Synonym: AZC_3027

Alternate gene names: 158424651

Gene position: 3460441-3461259 (Clockwise)

Preceding gene: 158424650

Following gene: 158424652

Centisome position: 64.44

GC content: 67.89

Gene sequence:

>819_bases
ATGACCAGCCGTCTCTTCAACCAGATGCTCGAGGGCATCGACCGCGGCGCCTTTCCGCGCACCCGCAAGTGGGCGTGGCG
CGGGGTCTACAACATGCTCTCGCGCTTCTGGCGCGACGACGACTGGCGCTTCATGAACTACGGCTATGTGCCGGAGGGCG
TGGCCTTCCCGCTGGAGGCGGCCGACGAACCCGAGCGGGCCTTCATCGGCCTCTATGCGCAGGCTGTGGACGGCCTGCCG
GTGGCTGGGGCGCGGGTGCTGGAGATCGGTTCGGGACGTGGCGGCGGCGCCCGCTATGTGGCGCGCTATCACGCGCCCGC
TTCGGTGACCGGGCTCGACTATTCGCCCGAGACCGTGCGCCTCGCCCGCAAGCTCAATGCCGACACGCCGAACCTCTCCT
TCGAGCAGGGCGATGCGGAACACCTGCCTTTCCCCGATGCCAGCTTCGACATCGCGGTGAACATCGAATCCTCCCACTGC
TATGCCAACATGCCCGCCTTCGTAGGCGAGGTGGCGCGGGTGCTGAAGCCGGGTGGCTGGTTCACCTTCGCCGACATGCG
CGGACGCGCGGCCATGACCGAGCTCGACCGCCAGATGGCGGTGCCGGGCCTCGATCTCGTGTCCGAGCGCAACATCTCTC
CCCGCGTCGTCGCGGCATTGGACGCGGCCGATGCCCGCAAGCAGGCCCGCATCGGCAAGGCGCTCCTGATGAAGCGCTTC
ATGTCCGAATTCGCCGGAGCCAAGGGCTCCATGCTCTACAAGGGCCTGTCACGGGGCGAGGTGATCTACGTCGCCCGCCG
CTATCGCAAGGCGGGCTGA

Upstream 100 bases:

>100_bases
CGCAACAGCGACGACGCCGAACTGATGCGCAAGGGCCGCGACTGGCTCGCCAAGGACATGCCGCCTCCGCGCGCGGCCAA
CGCCGCCGTTTGAGGCTCCC

Downstream 100 bases:

>100_bases
GGCCTCGCGCTTCCTCGCATCTGCGGCCAAGCCTTCGGTAGCCGGCTGGCGGCGCTGCGGCCCGGCCCAGTTCCGCTCGG
GAATTTGACCAGGGATTGGA

Product: methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MTSRLFNQMLEGIDRGAFPRTRKWAWRGVYNMLSRFWRDDDWRFMNYGYVPEGVAFPLEAADEPERAFIGLYAQAVDGLP
VAGARVLEIGSGRGGGARYVARYHAPASVTGLDYSPETVRLARKLNADTPNLSFEQGDAEHLPFPDASFDIAVNIESSHC
YANMPAFVGEVARVLKPGGWFTFADMRGRAAMTELDRQMAVPGLDLVSERNISPRVVAALDAADARKQARIGKALLMKRF
MSEFAGAKGSMLYKGLSRGEVIYVARRYRKAG

Sequences:

>Translated_272_residues
MTSRLFNQMLEGIDRGAFPRTRKWAWRGVYNMLSRFWRDDDWRFMNYGYVPEGVAFPLEAADEPERAFIGLYAQAVDGLP
VAGARVLEIGSGRGGGARYVARYHAPASVTGLDYSPETVRLARKLNADTPNLSFEQGDAEHLPFPDASFDIAVNIESSHC
YANMPAFVGEVARVLKPGGWFTFADMRGRAAMTELDRQMAVPGLDLVSERNISPRVVAALDAADARKQARIGKALLMKRF
MSEFAGAKGSMLYKGLSRGEVIYVARRYRKAG
>Mature_271_residues
TSRLFNQMLEGIDRGAFPRTRKWAWRGVYNMLSRFWRDDDWRFMNYGYVPEGVAFPLEAADEPERAFIGLYAQAVDGLPV
AGARVLEIGSGRGGGARYVARYHAPASVTGLDYSPETVRLARKLNADTPNLSFEQGDAEHLPFPDASFDIAVNIESSHCY
ANMPAFVGEVARVLKPGGWFTFADMRGRAAMTELDRQMAVPGLDLVSERNISPRVVAALDAADARKQARIGKALLMKRFM
SEFAGAKGSMLYKGLSRGEVIYVARRYRKAG

Specific function: Catalyzes the methylation of the lipid moiety of the intermediate compounds phthiotriol and glycosylated phenolphthiotriol dimycoserosates to form phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL) [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. Phthiotriol/phenolphthiotriol dimycocerosates methyltransferase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17540496, Length=244, Percent_Identity=28.6885245901639, Blast_Score=81, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 30186; Mature: 30055

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRLFNQMLEGIDRGAFPRTRKWAWRGVYNMLSRFWRDDDWRFMNYGYVPEGVAFPLEA
CCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCC
ADEPERAFIGLYAQAVDGLPVAGARVLEIGSGRGGGARYVARYHAPASVTGLDYSPETVR
CCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEECCCCEEECCCCCHHHHH
LARKLNADTPNLSFEQGDAEHLPFPDASFDIAVNIESSHCYANMPAFVGEVARVLKPGGW
HHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEECCHHHHHHHHHHHCCCCC
FTFADMRGRAAMTELDRQMAVPGLDLVSERNISPRVVAALDAADARKQARIGKALLMKRF
EEECCCCCCHHHHHHHHHHCCCCCHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHH
MSEFAGAKGSMLYKGLSRGEVIYVARRYRKAG
HHHHCCCCCCHHHHCCCCCCEEEEEHHHHCCC
>Mature Secondary Structure 
TSRLFNQMLEGIDRGAFPRTRKWAWRGVYNMLSRFWRDDDWRFMNYGYVPEGVAFPLEA
CHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCC
ADEPERAFIGLYAQAVDGLPVAGARVLEIGSGRGGGARYVARYHAPASVTGLDYSPETVR
CCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEECCCCEEECCCCCHHHHH
LARKLNADTPNLSFEQGDAEHLPFPDASFDIAVNIESSHCYANMPAFVGEVARVLKPGGW
HHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEECCHHHHHHHHHHHCCCCC
FTFADMRGRAAMTELDRQMAVPGLDLVSERNISPRVVAALDAADARKQARIGKALLMKRF
EEECCCCCCHHHHHHHHHHCCCCCHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHH
MSEFAGAKGSMLYKGLSRGEVIYVARRYRKAG
HHHHCCCCCCHHHHCCCCCCEEEEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]