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The map label for this gene is lysR [H]

Identifier: 158424634

GI number: 158424634

Start: 3442133

End: 3443125

Strand: Direct

Name: lysR [H]

Synonym: AZC_3010

Alternate gene names: 158424634

Gene position: 3442133-3443125 (Clockwise)

Preceding gene: 158424629

Following gene: 158424635

Centisome position: 64.1

GC content: 69.69

Gene sequence:

>993_bases
ATGACGGCACAGTGCACCGGCGCGACGTCTGACAGAATTGTCAAAGGCGTGCGCATGGCTAGTATGTTTTTGATGAGCCT
TCTCGCCTCGGACTGGGAAAACCAGCGCGCCTTCCTCGCCGTCCTGCGCACAGGCAGCCTGTCTGCCGCGGCGCGGGAAC
TCGGCCTCGCTCAGCCGACGGTGCGCCGAAGGATCGAGGCGCTGGAGCAGGCCCTCGGCACGCCACTCTTCACGCGCTCG
CCCGCCGGCCTCCTCCCCACCGAGGCTGCCCGGACGCTCGGCCCCCATGCGGAAGCCATGGCCGCTGCCGCCGCCGCATT
CCAGCGCGCGGCCTCGGGCCCGCGCGCAGAGATCTCGGGCACCGTGCGCATCACCGCCAGCGACATGATCGGGACGCAGG
TGCTTCCCGGCCTGATCGAACCGCTGATGGCGCGCCACCCGCGCCTGACGCTGGAAGTCCACCTCTCCAACCGCACTCAG
GATCTGCTGCGGCAGGAAGCGGACATCGCCGTGCGCATGGTGCGGCCCACCCAGTCCGCTCTGGTCATCCGCGCCATCGG
CATCGTGCGCCTGGGCCTGTTCGCGACGCCAGCCTTCGTGGAACGGCATGGGATGCCGGAGCGCCTCTCCGACCTGTCCC
GCTATCCGCTGATCGGTCCGGACCGCGACGCCGCCGACCTGCGGGCCACCGAACAGTTGCTGGGGCCGGACGTTCCGGGC
GCCCTCACCTATCGCACGGACAATCACCCCGCACAGTTCGCCGCCGTGCGGGCGGGCCTTGGGATCGGCGTCTGCCAGGT
CAATCTTGCGGCTCGCCCCCCGGCGCTGATCCCGATCCTGCCCGAGGCGTTCGAGATGCGGCTCGACACCTATCTGGTGA
TGCACGAGGACCTGAAGCGCGTGCGGCGTGTGCGCGTGGTGTTCGACCATCTGGCCCGCACGCTGGGCGCCTATTGCCAC
GGCACGACAGAGCCCACGTCCGGCGTGCTATAG

Upstream 100 bases:

>100_bases
GGCGGATGAGCGCCGCCGCCGTCTCGCCCCCGACCCCGCCGGTGGCGCCCAGCACCAGCGCCGTCCTGTTCGTGATGGTC
ATGTCCTCACTCCTCCATTC

Downstream 100 bases:

>100_bases
GAGCCCCTCGCAAGCAAAGGAGCGCGCCGTGGCGGACACGCTGACCATCTATGGCATCAAGAACTGCGACACCATGAAGA
AGGCCCGGGCCTTCCTCGAG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTAQCTGATSDRIVKGVRMASMFLMSLLASDWENQRAFLAVLRTGSLSAAARELGLAQPTVRRRIEALEQALGTPLFTRS
PAGLLPTEAARTLGPHAEAMAAAAAAFQRAASGPRAEISGTVRITASDMIGTQVLPGLIEPLMARHPRLTLEVHLSNRTQ
DLLRQEADIAVRMVRPTQSALVIRAIGIVRLGLFATPAFVERHGMPERLSDLSRYPLIGPDRDAADLRATEQLLGPDVPG
ALTYRTDNHPAQFAAVRAGLGIGVCQVNLAARPPALIPILPEAFEMRLDTYLVMHEDLKRVRRVRVVFDHLARTLGAYCH
GTTEPTSGVL

Sequences:

>Translated_330_residues
MTAQCTGATSDRIVKGVRMASMFLMSLLASDWENQRAFLAVLRTGSLSAAARELGLAQPTVRRRIEALEQALGTPLFTRS
PAGLLPTEAARTLGPHAEAMAAAAAAFQRAASGPRAEISGTVRITASDMIGTQVLPGLIEPLMARHPRLTLEVHLSNRTQ
DLLRQEADIAVRMVRPTQSALVIRAIGIVRLGLFATPAFVERHGMPERLSDLSRYPLIGPDRDAADLRATEQLLGPDVPG
ALTYRTDNHPAQFAAVRAGLGIGVCQVNLAARPPALIPILPEAFEMRLDTYLVMHEDLKRVRRVRVVFDHLARTLGAYCH
GTTEPTSGVL
>Mature_329_residues
TAQCTGATSDRIVKGVRMASMFLMSLLASDWENQRAFLAVLRTGSLSAAARELGLAQPTVRRRIEALEQALGTPLFTRSP
AGLLPTEAARTLGPHAEAMAAAAAAFQRAASGPRAEISGTVRITASDMIGTQVLPGLIEPLMARHPRLTLEVHLSNRTQD
LLRQEADIAVRMVRPTQSALVIRAIGIVRLGLFATPAFVERHGMPERLSDLSRYPLIGPDRDAADLRATEQLLGPDVPGA
LTYRTDNHPAQFAAVRAGLGIGVCQVNLAARPPALIPILPEAFEMRLDTYLVMHEDLKRVRRVRVVFDHLARTLGAYCHG
TTEPTSGVL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=186, Percent_Identity=31.1827956989247, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1789440, Length=291, Percent_Identity=24.7422680412371, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081978, Length=256, Percent_Identity=26.953125, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788481, Length=231, Percent_Identity=30.3030303030303, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789639, Length=181, Percent_Identity=25.414364640884, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787128, Length=230, Percent_Identity=26.5217391304348, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI145693193, Length=300, Percent_Identity=26, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787601, Length=139, Percent_Identity=27.3381294964029, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35666; Mature: 35535

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAQCTGATSDRIVKGVRMASMFLMSLLASDWENQRAFLAVLRTGSLSAAARELGLAQPT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHCCCCHH
VRRRIEALEQALGTPLFTRSPAGLLPTEAARTLGPHAEAMAAAAAAFQRAASGPRAEISG
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEECE
TVRITASDMIGTQVLPGLIEPLMARHPRLTLEVHLSNRTQDLLRQEADIAVRMVRPTQSA
EEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHEEEEECCCHHH
LVIRAIGIVRLGLFATPAFVERHGMPERLSDLSRYPLIGPDRDAADLRATEQLLGPDVPG
HHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCC
ALTYRTDNHPAQFAAVRAGLGIGVCQVNLAARPPALIPILPEAFEMRLDTYLVMHEDLKR
EEEEECCCCCHHHHHHHHCCCEEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHH
VRRVRVVFDHLARTLGAYCHGTTEPTSGVL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TAQCTGATSDRIVKGVRMASMFLMSLLASDWENQRAFLAVLRTGSLSAAARELGLAQPT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHCCCCHH
VRRRIEALEQALGTPLFTRSPAGLLPTEAARTLGPHAEAMAAAAAAFQRAASGPRAEISG
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEECE
TVRITASDMIGTQVLPGLIEPLMARHPRLTLEVHLSNRTQDLLRQEADIAVRMVRPTQSA
EEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHEEEEECCCHHH
LVIRAIGIVRLGLFATPAFVERHGMPERLSDLSRYPLIGPDRDAADLRATEQLLGPDVPG
HHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCC
ALTYRTDNHPAQFAAVRAGLGIGVCQVNLAARPPALIPILPEAFEMRLDTYLVMHEDLKR
EEEEECCCCCHHHHHHHHCCCEEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHH
VRRVRVVFDHLARTLGAYCHGTTEPTSGVL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]