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The map label for this gene is kamA [H]

Identifier: 158424552

GI number: 158424552

Start: 3348997

End: 3350124

Strand: Reverse

Name: kamA [H]

Synonym: AZC_2928

Alternate gene names: 158424552

Gene position: 3350124-3348997 (Counterclockwise)

Preceding gene: 158424557

Following gene: 158424551

Centisome position: 62.39

GC content: 69.77

Gene sequence:

>1128_bases
TTGCAGCCCGGCTCGCACCGGGACGGGCAAAACCGGCGCGGTTCCCATCCTCTGCCCCAACATGTTTGCGTGAGTGCCCC
CATGTCCACCCTGCGCACGGCCGATGACCTCATCGCGGCGGGCCTTGCCCCGGCGGCGGAGCGCGCCGTGCTCGATGCTG
TGGGCGCGCGCTATGCGGTGGCGGTCACGCCGGAACTGGTCGCGGCCATGGACCGGACCGATGCGTCCGATCCCATCGCC
CGCCAGTTCGTGCCCGACGTGGCCGAACTGCGCACCGATCCTCAGGAACTGGTCGATCCCATCGGGGATGACGCCCATTC
TCCGGTTCCTGGCATCGTGCACCGCTATCCCGACCGGGTGCTGCTGAAGCTGGTGGGTGTCTGCGCCGTCTATTGCCGCT
TCTGCTTCCGCCGCGAGATGGTGGGGCCGGGCGCGGAAACGGCCCTGACGCCCGACATGCTGGAGCGGGCGCTCGGCTAT
GTGGCCGCCCATCCCGAGGTCTGGGAGGTGATCCTCACCGGTGGCGATCCCTTCATGGTCTCGCCCCGCCGCATGGCGGA
CGTGGTGGGCCGGCTCGCCGCCATTCCCCATGTGAAGGTGGTGCGCTTTCACACCCGCGTGCCGATCGCCGCGCCCGAGC
GGGTGAGCGAGGAGATGGTACGGGCGTTGAAGGCACCGGGCGTCGCCGCCTACGTGGCCGTGCACGTCAACCATGCCCGC
GAGTTGGGCGATGCAGCGACCGCTGCACTGGGCCGGCTCGCCGATGCCGGCATTCCGCTGCTGTCGCAGACGGTGCTGCT
GAAGGGCGTGAACGACCGGGTGGAGACGCTCGATGCCTTGTTCCGTGCCCTCGTGGAACGGCGGGTGAAGCCCTATTACC
TGCACCATCCGGACCTTGCTCCCGGAACGGGCCATTTCCGCCTGAGCGTTCCGGAAGGGCAGGCCCTGGTGCGCGCGCTG
CGCGGCCGCCTCTCCGGCATTGCCCAGCCCACCTATGTGCTCGACATTCCGGGCGGCGCCGGCAAGGTGCCGCTGACGCC
CGGCTATCTCACGCCGCAAGGCGCGGGCTGGCATGTGGCCGACAATTGCGGCGGCATCCATGCCTATGGCGAGGCGGTGC
CGGGGTGA

Upstream 100 bases:

>100_bases
CGAGCCAGCATGGCAGGTCTCCGGCGGGCGCAGCAGCCAGCGCGTTGGCGCGGGGGGCTGCGGCCTATATAGAGCCAGAT
ATAGGGCTGGGCCGTCGGCT

Downstream 100 bases:

>100_bases
CGTCCGTCGAGGCTCTGGCTTGAGCTGGACCATGATTCCCCTGCGTTGGGATCACGCATAATATCTTTTGTTTTCAAACG
GCTGTGCGGTCCGTTAACGA

Product: lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MQPGSHRDGQNRRGSHPLPQHVCVSAPMSTLRTADDLIAAGLAPAAERAVLDAVGARYAVAVTPELVAAMDRTDASDPIA
RQFVPDVAELRTDPQELVDPIGDDAHSPVPGIVHRYPDRVLLKLVGVCAVYCRFCFRREMVGPGAETALTPDMLERALGY
VAAHPEVWEVILTGGDPFMVSPRRMADVVGRLAAIPHVKVVRFHTRVPIAAPERVSEEMVRALKAPGVAAYVAVHVNHAR
ELGDAATAALGRLADAGIPLLSQTVLLKGVNDRVETLDALFRALVERRVKPYYLHHPDLAPGTGHFRLSVPEGQALVRAL
RGRLSGIAQPTYVLDIPGGAGKVPLTPGYLTPQGAGWHVADNCGGIHAYGEAVPG

Sequences:

>Translated_375_residues
MQPGSHRDGQNRRGSHPLPQHVCVSAPMSTLRTADDLIAAGLAPAAERAVLDAVGARYAVAVTPELVAAMDRTDASDPIA
RQFVPDVAELRTDPQELVDPIGDDAHSPVPGIVHRYPDRVLLKLVGVCAVYCRFCFRREMVGPGAETALTPDMLERALGY
VAAHPEVWEVILTGGDPFMVSPRRMADVVGRLAAIPHVKVVRFHTRVPIAAPERVSEEMVRALKAPGVAAYVAVHVNHAR
ELGDAATAALGRLADAGIPLLSQTVLLKGVNDRVETLDALFRALVERRVKPYYLHHPDLAPGTGHFRLSVPEGQALVRAL
RGRLSGIAQPTYVLDIPGGAGKVPLTPGYLTPQGAGWHVADNCGGIHAYGEAVPG
>Mature_375_residues
MQPGSHRDGQNRRGSHPLPQHVCVSAPMSTLRTADDLIAAGLAPAAERAVLDAVGARYAVAVTPELVAAMDRTDASDPIA
RQFVPDVAELRTDPQELVDPIGDDAHSPVPGIVHRYPDRVLLKLVGVCAVYCRFCFRREMVGPGAETALTPDMLERALGY
VAAHPEVWEVILTGGDPFMVSPRRMADVVGRLAAIPHVKVVRFHTRVPIAAPERVSEEMVRALKAPGVAAYVAVHVNHAR
ELGDAATAALGRLADAGIPLLSQTVLLKGVNDRVETLDALFRALVERRVKPYYLHHPDLAPGTGHFRLSVPEGQALVRAL
RGRLSGIAQPTYVLDIPGGAGKVPLTPGYLTPQGAGWHVADNCGGIHAYGEAVPG

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=302, Percent_Identity=37.4172185430464, Blast_Score=202, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 39990; Mature: 39990

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPGSHRDGQNRRGSHPLPQHVCVSAPMSTLRTADDLIAAGLAPAAERAVLDAVGARYAV
CCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEE
AVTPELVAAMDRTDASDPIARQFVPDVAELRTDPQELVDPIGDDAHSPVPGIVHRYPDRV
EECHHHHHHHHCCCCCCHHHHHHCCCHHHHCCCHHHHHHHCCCCCCCCCCHHHHHCHHHH
LLKLVGVCAVYCRFCFRREMVGPGAETALTPDMLERALGYVAAHPEVWEVILTGGDPFMV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHEEEEEECCCCEEE
SPRRMADVVGRLAAIPHVKVVRFHTRVPIAAPERVSEEMVRALKAPGVAAYVAVHVNHAR
CHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEHHHHH
ELGDAATAALGRLADAGIPLLSQTVLLKGVNDRVETLDALFRALVERRVKPYYLHHPDLA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PGTGHFRLSVPEGQALVRALRGRLSGIAQPTYVLDIPGGAGKVPLTPGYLTPQGAGWHVA
CCCCCEEEECCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEC
DNCGGIHAYGEAVPG
CCCCCEECCCCCCCC
>Mature Secondary Structure
MQPGSHRDGQNRRGSHPLPQHVCVSAPMSTLRTADDLIAAGLAPAAERAVLDAVGARYAV
CCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEE
AVTPELVAAMDRTDASDPIARQFVPDVAELRTDPQELVDPIGDDAHSPVPGIVHRYPDRV
EECHHHHHHHHCCCCCCHHHHHHCCCHHHHCCCHHHHHHHCCCCCCCCCCHHHHHCHHHH
LLKLVGVCAVYCRFCFRREMVGPGAETALTPDMLERALGYVAAHPEVWEVILTGGDPFMV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHEEEEEECCCCEEE
SPRRMADVVGRLAAIPHVKVVRFHTRVPIAAPERVSEEMVRALKAPGVAAYVAVHVNHAR
CHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEHHHHH
ELGDAATAALGRLADAGIPLLSQTVLLKGVNDRVETLDALFRALVERRVKPYYLHHPDLA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PGTGHFRLSVPEGQALVRALRGRLSGIAQPTYVLDIPGGAGKVPLTPGYLTPQGAGWHVA
CCCCCEEEECCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEC
DNCGGIHAYGEAVPG
CCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]