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The map label for this gene is acxB [H]

Identifier: 158424546

GI number: 158424546

Start: 3337744

End: 3340074

Strand: Reverse

Name: acxB [H]

Synonym: AZC_2922

Alternate gene names: 158424546

Gene position: 3340074-3337744 (Counterclockwise)

Preceding gene: 158424547

Following gene: 158424545

Centisome position: 62.2

GC content: 64.95

Gene sequence:

>2331_bases
ATGAACATCAATGTCCGGGCCACCCAAACCAAAGGGGCCACGCGCGGCATCGTGCGCGGCGGCGAAACCCTGAAAGAGCA
TCGCGACCGCCTGATGGAGGCGACCCGCCGCACCAAGCATTATGCGGGCTTGGAGACGCTGGAACTGCGCGACACCCAGC
CGATCCACTACAACAAGCTGTTCTCCCGCCTGCGCGCCGGCGTGGTGGATGCACGCGAGACCGCCAAGAAGATCGCCGCC
TCGCCCATCGTCGAGCAGGAGGGCGAACTGTGTTTCACCCTTTACAATGCGGCGGGCGATAGCATCCTGACCTCCACCGG
CATCATCATCCATGTGGGGACCATGGGTGCGGCGATCAAATACATGATCGAGAACGACTGGGAGAGTAATCCCGGCATCA
ACGACAAGGATCTATTCTGCAACAACGACTGCCTCATCGGCAACGTGCATCCCTGCGACATCCATACCATCGTGCCCATC
TTCTGGGAGGGCGAACTGATCGGCTGGGTGGGCGGCGTCACCCACGTCATCGACACCGGCTCGGTCGGGCCGGGCTCCAT
GTCTACGGGGCAGGTGCAGCGCTTCGGCGACGGCTACCAGATCACCTGCCGCAAGGTGGGCGCCAACGACACCTTGTTCC
GCGACTGGCTGCACGAAAGCCAGCGCATGGTGCGCACCACCCGCTACTGGATGCTGGACGAGCGCACCCGCATCGCCGGC
TGCCACATGATCCGCAAACTGGTGGAAGAGGTGGTGGCCGAAGAGGGCATCGAGGCCTATTGGAAGTTCGCCTATGAGGC
GGTGGAGCACGGCCGGCAGGGGTTGCAGAACCGCATCAAGGCCATGACCATTCCCGGCACCTACCGGCAGGTGGGCTTCG
TGGACGTGCCCTACGCCCATGAGGACGTGCGGGTGCCTTCCGACTTCGCCAAGCTCGACACCATCATGCATTCGCCCTCG
GAGATCACCATCCGCGGCGACGGCACCTGGCGGCTCGATTTCGAGGGCGCCAGCCGCTGGGGCTGGCACACCTACAACGC
TCATCAGGTGAGCTTCACCTCCGGCATCTGGGTAATGATGACCCAGACGCTGATCCCGTCCGAGATGATCAATGACGGGG
CGGCCTACGGCACTGAGTTCCGCCTGCCCAAGGGCACCTGGATGAACCCGGACGACCGCCGTGTCGCCTTCTCCTACGCC
TGGCACTTCCTGGTATCGTCCTGGACCGCGCTGTGGCGCGGCCTGTCGCGCTCCTATTACGGGCGCGGCTATCTGGAGGA
GGTGAATGCTGGCAACGCCAACACCTCCAACTGGCTTCAAGGCGGCGGCTTCAACCAGTATGACGAGATCCATGCGGTGA
ACTCGTTCGAATGCGCCGCCAACGGCACCGGGGCGACCGCCGTGCACGACGGCCTCTCCCATGCCGCCGCCATCTGGAAC
CCGGAAGGCGACATGGGCGACATGGAGATCTGGGAGCTGGCCGAGCCGCTCGTCTATCTCGGGCGGCAGATCAAGGCCAA
TTCCGGCGGCGCCGGCAAGTATCGCGGCGGCTGCGGCTTCGAGAGCCTGCGCATGGTCTGGAACGCCAAGGACTGGACCA
TGTTCTTCATGGGCAACGGCCACATGTCCTCCGACTGGGGGCTGATGGGCGGCTATCCCGCCGCCTCCGGCTATCGCTTC
GCCGCCCATGACACCGGACTGAAGGAGCTGATCGCCTCCGGCGCCCCCATCCCGCTCGGCGGCGACACTGACCCGCAGAA
CCCCGTGTGGGACGCACTGATGCCCGACGCCAGGATCAAGCGCGACAAGCAGGCGATCACCACCGAGGAGATATTCAAGG
ACTACGACCTCTACCTCAACTACATGCGCGGCGGCCCCGGCTTCGGCGATCCACTCGACCGCGAGCCGCAGAGCGTGGTG
GACGACCTCAACGGCGGCTACCTGATCGAGCGCTTCGCTTCCCGCGTCTATGGCGTGGTGGCGGCGAAGGCGGCGGACGG
CGCCTTCACGCTGGACGGCCCGGCGACGCAGGCCCGGCGTGCCGAGATCCGCCGCGAGCGGCTCGCCAAGGCGGTGCCCA
CCCGCGAGTGGATGAAGGGCGAGCGGGAGAAGATCCTGGCCAAGGAGGCGGGCGACCACGTCAAGCAGATGTTCGCCTCC
TCCTTCAAGCTGGGGCCGAAGTTCTTCAAGGACTTCCGGACTTTCTGGGACCTGCCGGAGGACTGGAGGCTGCTGGAGGA
GGAGATCGGCATCCCGCACTACGGCTCGCACTACCACATGGACGTCTCCGAACTGCCGGACGTGAAGACGGTGCAGTTCG
TCGAGCAATAG

Upstream 100 bases:

>100_bases
GCCGGACGGCTTCGAAACCTTCCTCGACGGCCACCGCCTCTTCCACCTCAAGGAAATCTGAGCGCTGCCCTCACCGACAC
CCATTCAAGGAAACGTCAAG

Downstream 100 bases:

>100_bases
GCAGGACCGGGCACCGGGAGGCGTCTCTTCGGAGGTTCCTGCCGGTGCCCTTCGCCCCAATCATCAAGAAATCAGGAGGA
CACCCATGGCCTACACACGC

Product: acetone carboxylase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 776; Mature: 776

Protein sequence:

>776_residues
MNINVRATQTKGATRGIVRGGETLKEHRDRLMEATRRTKHYAGLETLELRDTQPIHYNKLFSRLRAGVVDARETAKKIAA
SPIVEQEGELCFTLYNAAGDSILTSTGIIIHVGTMGAAIKYMIENDWESNPGINDKDLFCNNDCLIGNVHPCDIHTIVPI
FWEGELIGWVGGVTHVIDTGSVGPGSMSTGQVQRFGDGYQITCRKVGANDTLFRDWLHESQRMVRTTRYWMLDERTRIAG
CHMIRKLVEEVVAEEGIEAYWKFAYEAVEHGRQGLQNRIKAMTIPGTYRQVGFVDVPYAHEDVRVPSDFAKLDTIMHSPS
EITIRGDGTWRLDFEGASRWGWHTYNAHQVSFTSGIWVMMTQTLIPSEMINDGAAYGTEFRLPKGTWMNPDDRRVAFSYA
WHFLVSSWTALWRGLSRSYYGRGYLEEVNAGNANTSNWLQGGGFNQYDEIHAVNSFECAANGTGATAVHDGLSHAAAIWN
PEGDMGDMEIWELAEPLVYLGRQIKANSGGAGKYRGGCGFESLRMVWNAKDWTMFFMGNGHMSSDWGLMGGYPAASGYRF
AAHDTGLKELIASGAPIPLGGDTDPQNPVWDALMPDARIKRDKQAITTEEIFKDYDLYLNYMRGGPGFGDPLDREPQSVV
DDLNGGYLIERFASRVYGVVAAKAADGAFTLDGPATQARRAEIRRERLAKAVPTREWMKGEREKILAKEAGDHVKQMFAS
SFKLGPKFFKDFRTFWDLPEDWRLLEEEIGIPHYGSHYHMDVSELPDVKTVQFVEQ

Sequences:

>Translated_776_residues
MNINVRATQTKGATRGIVRGGETLKEHRDRLMEATRRTKHYAGLETLELRDTQPIHYNKLFSRLRAGVVDARETAKKIAA
SPIVEQEGELCFTLYNAAGDSILTSTGIIIHVGTMGAAIKYMIENDWESNPGINDKDLFCNNDCLIGNVHPCDIHTIVPI
FWEGELIGWVGGVTHVIDTGSVGPGSMSTGQVQRFGDGYQITCRKVGANDTLFRDWLHESQRMVRTTRYWMLDERTRIAG
CHMIRKLVEEVVAEEGIEAYWKFAYEAVEHGRQGLQNRIKAMTIPGTYRQVGFVDVPYAHEDVRVPSDFAKLDTIMHSPS
EITIRGDGTWRLDFEGASRWGWHTYNAHQVSFTSGIWVMMTQTLIPSEMINDGAAYGTEFRLPKGTWMNPDDRRVAFSYA
WHFLVSSWTALWRGLSRSYYGRGYLEEVNAGNANTSNWLQGGGFNQYDEIHAVNSFECAANGTGATAVHDGLSHAAAIWN
PEGDMGDMEIWELAEPLVYLGRQIKANSGGAGKYRGGCGFESLRMVWNAKDWTMFFMGNGHMSSDWGLMGGYPAASGYRF
AAHDTGLKELIASGAPIPLGGDTDPQNPVWDALMPDARIKRDKQAITTEEIFKDYDLYLNYMRGGPGFGDPLDREPQSVV
DDLNGGYLIERFASRVYGVVAAKAADGAFTLDGPATQARRAEIRRERLAKAVPTREWMKGEREKILAKEAGDHVKQMFAS
SFKLGPKFFKDFRTFWDLPEDWRLLEEEIGIPHYGSHYHMDVSELPDVKTVQFVEQ
>Mature_776_residues
MNINVRATQTKGATRGIVRGGETLKEHRDRLMEATRRTKHYAGLETLELRDTQPIHYNKLFSRLRAGVVDARETAKKIAA
SPIVEQEGELCFTLYNAAGDSILTSTGIIIHVGTMGAAIKYMIENDWESNPGINDKDLFCNNDCLIGNVHPCDIHTIVPI
FWEGELIGWVGGVTHVIDTGSVGPGSMSTGQVQRFGDGYQITCRKVGANDTLFRDWLHESQRMVRTTRYWMLDERTRIAG
CHMIRKLVEEVVAEEGIEAYWKFAYEAVEHGRQGLQNRIKAMTIPGTYRQVGFVDVPYAHEDVRVPSDFAKLDTIMHSPS
EITIRGDGTWRLDFEGASRWGWHTYNAHQVSFTSGIWVMMTQTLIPSEMINDGAAYGTEFRLPKGTWMNPDDRRVAFSYA
WHFLVSSWTALWRGLSRSYYGRGYLEEVNAGNANTSNWLQGGGFNQYDEIHAVNSFECAANGTGATAVHDGLSHAAAIWN
PEGDMGDMEIWELAEPLVYLGRQIKANSGGAGKYRGGCGFESLRMVWNAKDWTMFFMGNGHMSSDWGLMGGYPAASGYRF
AAHDTGLKELIASGAPIPLGGDTDPQNPVWDALMPDARIKRDKQAITTEEIFKDYDLYLNYMRGGPGFGDPLDREPQSVV
DDLNGGYLIERFASRVYGVVAAKAADGAFTLDGPATQARRAEIRRERLAKAVPTREWMKGEREKILAKEAGDHVKQMFAS
SFKLGPKFFKDFRTFWDLPEDWRLLEEEIGIPHYGSHYHMDVSELPDVKTVQFVEQ

Specific function: Catalyzes the carboxylation of acetone to form acetoacetate. Has a reduced activity on butanone, and no activity on 2-pentatone, 3-pentatone, 2-hexanone, chloroacetone, pyruvate, phosphoenolpyruvate, acetaldehyde, propionaldehyde and propylene oxide [H]

COG id: COG0146

COG function: function code EQ; N-methylhydantoinase B/acetone carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003692 [H]

Pfam domain/function: PF02538 Hydantoinase_B [H]

EC number: =6.4.1.6 [H]

Molecular weight: Translated: 87063; Mature: 87063

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNINVRATQTKGATRGIVRGGETLKEHRDRLMEATRRTKHYAGLETLELRDTQPIHYNKL
CCCEEEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHH
FSRLRAGVVDARETAKKIAASPIVEQEGELCFTLYNAAGDSILTSTGIIIHVGTMGAAIK
HHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEECCCEEEEECCCCHHHH
YMIENDWESNPGINDKDLFCNNDCLIGNVHPCDIHTIVPIFWEGELIGWVGGVTHVIDTG
HHHHCCCCCCCCCCCCCEEECCCEEECCCCCCCCEEEEEEEECCEEEEHHCCHHHHEECC
SVGPGSMSTGQVQRFGDGYQITCRKVGANDTLFRDWLHESQRMVRTTRYWMLDERTRIAG
CCCCCCCCCCCHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHEECCCHHHHH
CHMIRKLVEEVVAEEGIEAYWKFAYEAVEHGRQGLQNRIKAMTIPGTYRQVGFVDVPYAH
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHCCCEEECCCCC
EDVRVPSDFAKLDTIMHSPSEITIRGDGTWRLDFEGASRWGWHTYNAHQVSFTSGIWVMM
CCCCCCHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCCCCCCCEEEEECCCEEEEH
TQTLIPSEMINDGAAYGTEFRLPKGTWMNPDDRRVAFSYAWHFLVSSWTALWRGLSRSYY
HHHHCCHHHHCCCCCCCCEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHC
GRGYLEEVNAGNANTSNWLQGGGFNQYDEIHAVNSFECAANGTGATAVHDGLSHAAAIWN
CCCCHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEECCCCCCCHHHHHHHHHHHEEEC
PEGDMGDMEIWELAEPLVYLGRQIKANSGGAGKYRGGCGFESLRMVWNAKDWTMFFMGNG
CCCCCCCCHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEECC
HMSSDWGLMGGYPAASGYRFAAHDTGLKELIASGAPIPLGGDTDPQNPVWDALMPDARIK
CCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCHHHH
RDKQAITTEEIFKDYDLYLNYMRGGPGFGDPLDREPQSVVDDLNGGYLIERFASRVYGVV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHH
AAKAADGAFTLDGPATQARRAEIRRERLAKAVPTREWMKGEREKILAKEAGDHVKQMFAS
EEECCCCCEEECCCHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
SFKLGPKFFKDFRTFWDLPEDWRLLEEEIGIPHYGSHYHMDVSELPDVKTVQFVEQ
HHCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEECHHHCCCCCHHHHHCC
>Mature Secondary Structure
MNINVRATQTKGATRGIVRGGETLKEHRDRLMEATRRTKHYAGLETLELRDTQPIHYNKL
CCCEEEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHH
FSRLRAGVVDARETAKKIAASPIVEQEGELCFTLYNAAGDSILTSTGIIIHVGTMGAAIK
HHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEECCCEEEEECCCCHHHH
YMIENDWESNPGINDKDLFCNNDCLIGNVHPCDIHTIVPIFWEGELIGWVGGVTHVIDTG
HHHHCCCCCCCCCCCCCEEECCCEEECCCCCCCCEEEEEEEECCEEEEHHCCHHHHEECC
SVGPGSMSTGQVQRFGDGYQITCRKVGANDTLFRDWLHESQRMVRTTRYWMLDERTRIAG
CCCCCCCCCCCHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHEECCCHHHHH
CHMIRKLVEEVVAEEGIEAYWKFAYEAVEHGRQGLQNRIKAMTIPGTYRQVGFVDVPYAH
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHCCCEEECCCCC
EDVRVPSDFAKLDTIMHSPSEITIRGDGTWRLDFEGASRWGWHTYNAHQVSFTSGIWVMM
CCCCCCHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCCCCCCCEEEEECCCEEEEH
TQTLIPSEMINDGAAYGTEFRLPKGTWMNPDDRRVAFSYAWHFLVSSWTALWRGLSRSYY
HHHHCCHHHHCCCCCCCCEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHC
GRGYLEEVNAGNANTSNWLQGGGFNQYDEIHAVNSFECAANGTGATAVHDGLSHAAAIWN
CCCCHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEECCCCCCCHHHHHHHHHHHEEEC
PEGDMGDMEIWELAEPLVYLGRQIKANSGGAGKYRGGCGFESLRMVWNAKDWTMFFMGNG
CCCCCCCCHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEECC
HMSSDWGLMGGYPAASGYRFAAHDTGLKELIASGAPIPLGGDTDPQNPVWDALMPDARIK
CCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCHHHH
RDKQAITTEEIFKDYDLYLNYMRGGPGFGDPLDREPQSVVDDLNGGYLIERFASRVYGVV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHH
AAKAADGAFTLDGPATQARRAEIRRERLAKAVPTREWMKGEREKILAKEAGDHVKQMFAS
EEECCCCCEEECCCHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
SFKLGPKFFKDFRTFWDLPEDWRLLEEEIGIPHYGSHYHMDVSELPDVKTVQFVEQ
HHCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEECHHHCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12003937 [H]