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The map label for this gene is appC [H]

Identifier: 158424533

GI number: 158424533

Start: 3322191

End: 3323069

Strand: Reverse

Name: appC [H]

Synonym: AZC_2909

Alternate gene names: 158424533

Gene position: 3323069-3322191 (Counterclockwise)

Preceding gene: 158424534

Following gene: 158424532

Centisome position: 61.88

GC content: 67.58

Gene sequence:

>879_bases
ATGGATCGCGCCGCGCCGCTCGCCCGCTTCTTCGCCGAGTTCCGCGAGAACCGCTCGGCGGTGCTCGGCCTCGCCATCGT
GGTGACGCTGCTGGTGCTGGCGGTGCTGGCCCCGCTCATCACGCCGCAGGACCCCTATGACCTCGCTTCGCTCAGCCTGC
GCGATGCGCGCCGTGCGCCGGGCTTCGTGGGCACCGGCGGCTATGTGCACTGGCTCGGCACGGATGCGCAGGGCCGCGAC
CTCTTCTCTGCCATCCTCTATGGACTGCGAATCTCCATCGAGATGGGACTGGTGGCGGGTGCCATCGGTCTCGTGCTGGG
GGCTGGCGTCGGCACCATGGCGGCCTATGTGGGCGGACGCACCGAGGCCTTCATCATGCGCCTCGTGGACCTTCAACTGT
CCTTTCCGGCCATTCTGCTCGCCTTCGTGCTGGCGGCGCTGCTGGGCCAGGGCAAGGCGCAACTGGTGATGGCGCTGGTG
GCTGCCCAGTATGCCTATTTCGCCCGCACCGCCCATGGCGCGGCATCCGCAGAGCGCAGCAAGGACTATGTGGAGGCCGC
GCTCTCCACGCCGCTGCCCGCCTGGCGCGTGGTGCTCCGCCACATCCTGCCCAATGCGCTGCCGCCGCTTATCGTGGTGG
CCACCGTGCAGGTCGCGAGCGCCATTTCGCTGGAGGCGACGCTCTCCTTCCTTGGGGTCGGCCTGCCGCCCACCGAGCCT
TCGCTCGGCATGCTGATCGCCAACGGCTTTCCCTACATGCTGTCCGGCCGCTACTGGATTTCCATCTATCCGGGCGTCGC
GCTCATCGTCCTCATCTTCTCGGTCAATCTCGTGGGCGATCAGATCCGCGACCAGCTCAATCCGAGGCTGAAGCGATGA

Upstream 100 bases:

>100_bases
CCTATCTCATGCTGGTGGCACTGTTCTTCATCGGCATCAATCTGGTGGTGGACCTCTCCTATGCCGCGCTCGACCCGCGC
CTGCGGAAAGGCCGCGCCTG

Downstream 100 bases:

>100_bases
ACGCCCCCTTGCTGGAGGTGCGCGGCCTCTCCACCCAGTTTCCCACCCGCACCGGCCTCGTGAAGGCGGTGAACGACGTC
TCCTTCTTCGTCCGCCGGGG

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MDRAAPLARFFAEFRENRSAVLGLAIVVTLLVLAVLAPLITPQDPYDLASLSLRDARRAPGFVGTGGYVHWLGTDAQGRD
LFSAILYGLRISIEMGLVAGAIGLVLGAGVGTMAAYVGGRTEAFIMRLVDLQLSFPAILLAFVLAALLGQGKAQLVMALV
AAQYAYFARTAHGAASAERSKDYVEAALSTPLPAWRVVLRHILPNALPPLIVVATVQVASAISLEATLSFLGVGLPPTEP
SLGMLIANGFPYMLSGRYWISIYPGVALIVLIFSVNLVGDQIRDQLNPRLKR

Sequences:

>Translated_292_residues
MDRAAPLARFFAEFRENRSAVLGLAIVVTLLVLAVLAPLITPQDPYDLASLSLRDARRAPGFVGTGGYVHWLGTDAQGRD
LFSAILYGLRISIEMGLVAGAIGLVLGAGVGTMAAYVGGRTEAFIMRLVDLQLSFPAILLAFVLAALLGQGKAQLVMALV
AAQYAYFARTAHGAASAERSKDYVEAALSTPLPAWRVVLRHILPNALPPLIVVATVQVASAISLEATLSFLGVGLPPTEP
SLGMLIANGFPYMLSGRYWISIYPGVALIVLIFSVNLVGDQIRDQLNPRLKR
>Mature_292_residues
MDRAAPLARFFAEFRENRSAVLGLAIVVTLLVLAVLAPLITPQDPYDLASLSLRDARRAPGFVGTGGYVHWLGTDAQGRD
LFSAILYGLRISIEMGLVAGAIGLVLGAGVGTMAAYVGGRTEAFIMRLVDLQLSFPAILLAFVLAALLGQGKAQLVMALV
AAQYAYFARTAHGAASAERSKDYVEAALSTPLPAWRVVLRHILPNALPPLIVVATVQVASAISLEATLSFLGVGLPPTEP
SLGMLIANGFPYMLSGRYWISIYPGVALIVLIFSVNLVGDQIRDQLNPRLKR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=266, Percent_Identity=37.593984962406, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1787054, Length=286, Percent_Identity=31.8181818181818, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1789964, Length=288, Percent_Identity=36.4583333333333, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1789889, Length=221, Percent_Identity=31.2217194570136, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787498, Length=276, Percent_Identity=32.2463768115942, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788505, Length=228, Percent_Identity=30.2631578947368, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787549, Length=271, Percent_Identity=25.830258302583, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31066; Mature: 31066

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRAAPLARFFAEFRENRSAVLGLAIVVTLLVLAVLAPLITPQDPYDLASLSLRDARRAP
CCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
GFVGTGGYVHWLGTDAQGRDLFSAILYGLRISIEMGLVAGAIGLVLGAGVGTMAAYVGGR
CCEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC
TEAFIMRLVDLQLSFPAILLAFVLAALLGQGKAQLVMALVAAQYAYFARTAHGAASAERS
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
KDYVEAALSTPLPAWRVVLRHILPNALPPLIVVATVQVASAISLEATLSFLGVGLPPTEP
HHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SLGMLIANGFPYMLSGRYWISIYPGVALIVLIFSVNLVGDQIRDQLNPRLKR
CCCEEEECCCCCEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDRAAPLARFFAEFRENRSAVLGLAIVVTLLVLAVLAPLITPQDPYDLASLSLRDARRAP
CCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
GFVGTGGYVHWLGTDAQGRDLFSAILYGLRISIEMGLVAGAIGLVLGAGVGTMAAYVGGR
CCEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC
TEAFIMRLVDLQLSFPAILLAFVLAALLGQGKAQLVMALVAAQYAYFARTAHGAASAERS
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
KDYVEAALSTPLPAWRVVLRHILPNALPPLIVVATVQVASAISLEATLSFLGVGLPPTEP
HHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SLGMLIANGFPYMLSGRYWISIYPGVALIVLIFSVNLVGDQIRDQLNPRLKR
CCCEEEECCCCCEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]