Click here to switch to the map view.

The map label for this gene is yeaE [H]

Identifier: 158424524

GI number: 158424524

Start: 3310439

End: 3311275

Strand: Reverse

Name: yeaE [H]

Synonym: AZC_2900

Alternate gene names: 158424524

Gene position: 3311275-3310439 (Counterclockwise)

Preceding gene: 158424525

Following gene: 158424519

Centisome position: 61.67

GC content: 68.7

Gene sequence:

>837_bases
ATGGCCAAGACCGTGACGCTGCCGGGCGGGGAAACCGTGCCGGCGCTGGGGCAGGGCACCTGGTTCATGGGCGAGCTGCC
CGCCCGCCGCCCCGACGAGATCGCCGCGCTGCGTGCCGGCATCGAGCTTGGCCTGACCCTCGTGGACACCGCCGAAATGT
ACGGTGACGGCCGCACCGAGGAACTGGTGGGCGCCGCGCTGAAGGACGGTTTCCGCGAGCAGGTGTTCCTCGTCAGCAAG
GTCTATCCGCACAATGCCAGCCGCGCCGGCGTCATCGCCGCCTGCGAGCGCAGTCTGCGCCGGCTCGGTACCGACCGGCT
GGACCTCTATCTGCTGCACTGGCGCGGCAGCCATCCTTTCGAGGACACCATCGCCGGCTTCGAGACCCTCCAGAAGGCCG
GCAAGATCCGCCACTGGGGCGTGAGCAACCTCGATACCGACGACATGGAGGAACTGCTGGATGCGGGCGGTCGCGCCTGC
GCCGTCAACCAGATCCTCTACAATCCCTCCCGGCGGGGGCCGGAGTTCGACCTTCTGCCGTTCCAGCAGGAGCGGGGCAT
TCCCACCATGGCCTACAGCCCCATCGAGCAGGGCCGCCTGCCGCGGGGCGGGGCGCTCGGCCGCGTGGCCTCGAAACATG
GTGTCGATCCGTTTCAGGTGGCGCTGGCCTGGGTGCTGCGGCGGCCGGATGTGATCGCCATTCCGAAGGCGGCGAGCCTT
GATCACGTGAAGGCGAACGTGGCGGCGCGCGATCTCGTGCTGGATGCGGATGACCTTGCCGATATCGACGGCGATTTCCC
GCCGCCCAGGCGCAAGCGCAGCCTGGAGATGCTTTAG

Upstream 100 bases:

>100_bases
CGTCTTTCTCGCGACGGCACAGGTCTTTTTCGCCCCCGGCGGAGTTCCGCTCTCAGGCGAACGCCTTTAACGTCCGCCGT
CCAGTGAAGGGAGGGCGACA

Downstream 100 bases:

>100_bases
GCGGTCGCCGCCAGCGGCGCGGGAGCCGCATCGTCCTCCCTGTGGGCGCGGGCGATCAGCACCGCGTCCACGTCCGGGAT
CTCGGTCTTGAGGCGGGCTT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MAKTVTLPGGETVPALGQGTWFMGELPARRPDEIAALRAGIELGLTLVDTAEMYGDGRTEELVGAALKDGFREQVFLVSK
VYPHNASRAGVIAACERSLRRLGTDRLDLYLLHWRGSHPFEDTIAGFETLQKAGKIRHWGVSNLDTDDMEELLDAGGRAC
AVNQILYNPSRRGPEFDLLPFQQERGIPTMAYSPIEQGRLPRGGALGRVASKHGVDPFQVALAWVLRRPDVIAIPKAASL
DHVKANVAARDLVLDADDLADIDGDFPPPRRKRSLEML

Sequences:

>Translated_278_residues
MAKTVTLPGGETVPALGQGTWFMGELPARRPDEIAALRAGIELGLTLVDTAEMYGDGRTEELVGAALKDGFREQVFLVSK
VYPHNASRAGVIAACERSLRRLGTDRLDLYLLHWRGSHPFEDTIAGFETLQKAGKIRHWGVSNLDTDDMEELLDAGGRAC
AVNQILYNPSRRGPEFDLLPFQQERGIPTMAYSPIEQGRLPRGGALGRVASKHGVDPFQVALAWVLRRPDVIAIPKAASL
DHVKANVAARDLVLDADDLADIDGDFPPPRRKRSLEML
>Mature_277_residues
AKTVTLPGGETVPALGQGTWFMGELPARRPDEIAALRAGIELGLTLVDTAEMYGDGRTEELVGAALKDGFREQVFLVSKV
YPHNASRAGVIAACERSLRRLGTDRLDLYLLHWRGSHPFEDTIAGFETLQKAGKIRHWGVSNLDTDDMEELLDAGGRACA
VNQILYNPSRRGPEFDLLPFQQERGIPTMAYSPIEQGRLPRGGALGRVASKHGVDPFQVALAWVLRRPDVIAIPKAASLD
HVKANVAARDLVLDADDLADIDGDFPPPRRKRSLEML

Specific function: Unknown

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI24497577, Length=301, Percent_Identity=26.2458471760797, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI5174391, Length=301, Percent_Identity=26.2458471760797, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI310109922, Length=281, Percent_Identity=28.8256227758007, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI223468663, Length=300, Percent_Identity=27.3333333333333, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI45446745, Length=301, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI4503285, Length=301, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI5453543, Length=301, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI310109920, Length=301, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI24497585, Length=299, Percent_Identity=28.0936454849498, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI4502049, Length=301, Percent_Identity=27.906976744186, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI291291012, Length=265, Percent_Identity=26.4150943396226, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI223718702, Length=180, Percent_Identity=30.5555555555556, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1788081, Length=282, Percent_Identity=53.5460992907801, Blast_Score=298, Evalue=2e-82,
Organism=Escherichia coli, GI1788070, Length=304, Percent_Identity=30.5921052631579, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI87081735, Length=297, Percent_Identity=29.2929292929293, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1786400, Length=254, Percent_Identity=28.740157480315, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI87082198, Length=265, Percent_Identity=29.811320754717, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1789199, Length=335, Percent_Identity=30.1492537313433, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787674, Length=255, Percent_Identity=28.6274509803922, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI48994888, Length=279, Percent_Identity=30.8243727598566, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789375, Length=309, Percent_Identity=26.537216828479, Blast_Score=75, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71998625, Length=282, Percent_Identity=29.7872340425532, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17537077, Length=306, Percent_Identity=28.1045751633987, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17537075, Length=306, Percent_Identity=27.7777777777778, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17550248, Length=299, Percent_Identity=26.7558528428094, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17561298, Length=282, Percent_Identity=28.7234042553192, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17552492, Length=267, Percent_Identity=27.7153558052434, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538386, Length=280, Percent_Identity=27.8571428571429, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17564128, Length=305, Percent_Identity=25.5737704918033, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17561300, Length=281, Percent_Identity=27.4021352313167, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17566692, Length=287, Percent_Identity=25.4355400696864, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6324694, Length=297, Percent_Identity=28.6195286195286, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320576, Length=316, Percent_Identity=29.746835443038, Blast_Score=106, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6320079, Length=250, Percent_Identity=28.4, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45553081, Length=296, Percent_Identity=29.3918918918919, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24663317, Length=301, Percent_Identity=25.9136212624585, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24662789, Length=298, Percent_Identity=27.8523489932886, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24657054, Length=290, Percent_Identity=26.2068965517241, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI20129731, Length=293, Percent_Identity=25.938566552901, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646159, Length=156, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 30440; Mature: 30309

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTVTLPGGETVPALGQGTWFMGELPARRPDEIAALRAGIELGLTLVDTAEMYGDGRTE
CCCEEECCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCEEEEEHHHHHCCCCHH
ELVGAALKDGFREQVFLVSKVYPHNASRAGVIAACERSLRRLGTDRLDLYLLHWRGSHPF
HHHHHHHHHCHHHHEEHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCH
EDTIAGFETLQKAGKIRHWGVSNLDTDDMEELLDAGGRACAVNQILYNPSRRGPEFDLLP
HHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHCCCCEEEHHHHHCCCCCCCCCCCCCC
FQQERGIPTMAYSPIEQGRLPRGGALGRVASKHGVDPFQVALAWVLRRPDVIAIPKAASL
CHHHCCCCCEEECCHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCH
DHVKANVAARDLVLDADDLADIDGDFPPPRRKRSLEML
HHHHHHHHHHHEEECCHHHHHCCCCCCCCHHCCCCCCC
>Mature Secondary Structure 
AKTVTLPGGETVPALGQGTWFMGELPARRPDEIAALRAGIELGLTLVDTAEMYGDGRTE
CCEEECCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCEEEEEHHHHHCCCCHH
ELVGAALKDGFREQVFLVSKVYPHNASRAGVIAACERSLRRLGTDRLDLYLLHWRGSHPF
HHHHHHHHHCHHHHEEHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCH
EDTIAGFETLQKAGKIRHWGVSNLDTDDMEELLDAGGRACAVNQILYNPSRRGPEFDLLP
HHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHCCCCEEEHHHHHCCCCCCCCCCCCCC
FQQERGIPTMAYSPIEQGRLPRGGALGRVASKHGVDPFQVALAWVLRRPDVIAIPKAASL
CHHHCCCCCEEECCHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCH
DHVKANVAARDLVLDADDLADIDGDFPPPRRKRSLEML
HHHHHHHHHHHEEECCHHHHHCCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]