Click here to switch to the map view.

The map label for this gene is uxuA [H]

Identifier: 158424392

GI number: 158424392

Start: 3148169

End: 3149389

Strand: Reverse

Name: uxuA [H]

Synonym: AZC_2768

Alternate gene names: 158424392

Gene position: 3149389-3148169 (Counterclockwise)

Preceding gene: 158424394

Following gene: 158424391

Centisome position: 58.65

GC content: 69.21

Gene sequence:

>1221_bases
ATGCGGCAGACATGGCGATGGTTCGGGCCCAAGGACATCGTGCCCTTGAGCGCGGTGCGCCAGGCCGGCGCTCAGGGCAT
CGTGACCGCACTCCATCACGTGCCGACCGGGTCCGACTGGACGCTGGAGGAGATCCGCAAGCGGCAGGATCTCGTGAGCG
GCGCGGGGAGCGCCCCCACGGGCCTCAGCTGGGATGTGGTGGAGAGCCTGCCGGTGTCCGAGGACATCAAGCGCCAGACC
GGCGCGTGGCGCGAGCATATCGCCTCCTACAAGCGCTCCATGGCCGCGCTGGCGCAGGCGGGCATCCAGACCATCTGCTA
CAATTTCATGCCGGTTCTGGACTGGACCCGCACCGACCTGCGCTATCGCGTGGCTCATGGCGGGGAGGCCATGCGCTTCG
ATCTCGTGGACTTTGCCGCCTTCGACCTGTTCGTACTGACCCGCCCCGCCGCCCAGGAGGATTACGGCCCGGCCATCAAG
GAGGCCGCCGCCGCCCGCCACGCCGCCATGAGCGAGGACGATCGCAAGCAACTCGCCGCCAACCTCACCGCCGGCCTGCC
CGGCGCGGCGGATGGCTGGTCGCTGGACGGCGTGCGCGAACAGCTCGCGCTTTACGACCACATCAGCCCGGATCGCCTGC
GCCAGCATCTGGTGGACTTCCTGTCCGAGGTGGTGCCGGAGGCGGAAAAGCTCGGCCTGCGCCTGTGCTGCCATCCGGAC
GATCCGCCGTTCCCGCTGCTCGGCCTGCCGCGCATCGTCTCCACCGAGGCCGACTACCGCTTCATGCTGGATGCGGTGGA
CAGCCCGGCCAATGGCGTCACTTTGTGCTCCGGCTCTCTGGGCGTGCGGCCGGACAATGATCTGCCGGGCATGGCGGAGC
GTCTCGGTCCGCGCATTCATTTCGTGCATCTGCGCAACATCCGCCGGCAGGAGCCGGTGGACGGCCTGCGCCGCTCCTTC
TTCGAGGACGAGCATCTGGCGGGCGAGACCGACATGGTCGCCACCATCGCCGCCCTCCAGACGGAGGAAGCGCGCCGCCG
CGCGGAAGGCCGGACGGATTGGGAAATCCCCATGCGGCCGGACCATGGGCAGGACATTCTGGACGACATCGGGCGGGGCG
GGCAGCCGGGTTATCCCGCCATCGGCCGCCTGAAGGGACTGGCGGAACTGCGGGGCATCATGACCGCGCTCGCCCATCCC
CTGCACCTCGAACGCGCCTGA

Upstream 100 bases:

>100_bases
CCGCAACGTGGGGCGGGCCCTGACCTCTCGGCTTTACGAAACTGGGATACTGGAATACGAGAAATCATCAGGACGCCCAC
GGCGGAATCGGGAGGACAGG

Downstream 100 bases:

>100_bases
CCGGGGCGCGTTCGTGCCGCGCGTCAAGCGCACGCTGCCGGGCTTCGACCTCGCCGCCGCGCTTTCGGGGGCGCAGGTGG
ATCGCGCCTTGCCGATCGGG

Product: mannonate dehydratase

Products: NA

Alternate protein names: D-mannonate hydrolase [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MRQTWRWFGPKDIVPLSAVRQAGAQGIVTALHHVPTGSDWTLEEIRKRQDLVSGAGSAPTGLSWDVVESLPVSEDIKRQT
GAWREHIASYKRSMAALAQAGIQTICYNFMPVLDWTRTDLRYRVAHGGEAMRFDLVDFAAFDLFVLTRPAAQEDYGPAIK
EAAAARHAAMSEDDRKQLAANLTAGLPGAADGWSLDGVREQLALYDHISPDRLRQHLVDFLSEVVPEAEKLGLRLCCHPD
DPPFPLLGLPRIVSTEADYRFMLDAVDSPANGVTLCSGSLGVRPDNDLPGMAERLGPRIHFVHLRNIRRQEPVDGLRRSF
FEDEHLAGETDMVATIAALQTEEARRRAEGRTDWEIPMRPDHGQDILDDIGRGGQPGYPAIGRLKGLAELRGIMTALAHP
LHLERA

Sequences:

>Translated_406_residues
MRQTWRWFGPKDIVPLSAVRQAGAQGIVTALHHVPTGSDWTLEEIRKRQDLVSGAGSAPTGLSWDVVESLPVSEDIKRQT
GAWREHIASYKRSMAALAQAGIQTICYNFMPVLDWTRTDLRYRVAHGGEAMRFDLVDFAAFDLFVLTRPAAQEDYGPAIK
EAAAARHAAMSEDDRKQLAANLTAGLPGAADGWSLDGVREQLALYDHISPDRLRQHLVDFLSEVVPEAEKLGLRLCCHPD
DPPFPLLGLPRIVSTEADYRFMLDAVDSPANGVTLCSGSLGVRPDNDLPGMAERLGPRIHFVHLRNIRRQEPVDGLRRSF
FEDEHLAGETDMVATIAALQTEEARRRAEGRTDWEIPMRPDHGQDILDDIGRGGQPGYPAIGRLKGLAELRGIMTALAHP
LHLERA
>Mature_406_residues
MRQTWRWFGPKDIVPLSAVRQAGAQGIVTALHHVPTGSDWTLEEIRKRQDLVSGAGSAPTGLSWDVVESLPVSEDIKRQT
GAWREHIASYKRSMAALAQAGIQTICYNFMPVLDWTRTDLRYRVAHGGEAMRFDLVDFAAFDLFVLTRPAAQEDYGPAIK
EAAAARHAAMSEDDRKQLAANLTAGLPGAADGWSLDGVREQLALYDHISPDRLRQHLVDFLSEVVPEAEKLGLRLCCHPD
DPPFPLLGLPRIVSTEADYRFMLDAVDSPANGVTLCSGSLGVRPDNDLPGMAERLGPRIHFVHLRNIRRQEPVDGLRRSF
FEDEHLAGETDMVATIAALQTEEARRRAEGRTDWEIPMRPDHGQDILDDIGRGGQPGYPAIGRLKGLAELRGIMTALAHP
LHLERA

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1312

COG function: function code G; D-mannonate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannonate dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1790778, Length=397, Percent_Identity=52.1410579345088, Blast_Score=434, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004628
- InterPro:   IPR013022 [H]

Pfam domain/function: PF03786 UxuA [H]

EC number: =4.2.1.8 [H]

Molecular weight: Translated: 44915; Mature: 44915

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQTWRWFGPKDIVPLSAVRQAGAQGIVTALHHVPTGSDWTLEEIRKRQDLVSGAGSAPT
CCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCC
GLSWDVVESLPVSEDIKRQTGAWREHIASYKRSMAALAQAGIQTICYNFMPVLDWTRTDL
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCC
RYRVAHGGEAMRFDLVDFAAFDLFVLTRPAAQEDYGPAIKEAAAARHAAMSEDDRKQLAA
EEEECCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
NLTAGLPGAADGWSLDGVREQLALYDHISPDRLRQHLVDFLSEVVPEAEKLGLRLCCHPD
HHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHCCEEEEECCC
DPPFPLLGLPRIVSTEADYRFMLDAVDSPANGVTLCSGSLGVRPDNDLPGMAERLGPRIH
CCCCCCCCCCHHHCCCCCHHEEEHHCCCCCCCEEEECCCCCCCCCCCCCCHHHHCCCCEE
FVHLRNIRRQEPVDGLRRSFFEDEHLAGETDMVATIAALQTEEARRRAEGRTDWEIPMRP
EEEHHHCCCCCCHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DHGQDILDDIGRGGQPGYPAIGRLKGLAELRGIMTALAHPLHLERA
CCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCCC
>Mature Secondary Structure
MRQTWRWFGPKDIVPLSAVRQAGAQGIVTALHHVPTGSDWTLEEIRKRQDLVSGAGSAPT
CCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCC
GLSWDVVESLPVSEDIKRQTGAWREHIASYKRSMAALAQAGIQTICYNFMPVLDWTRTDL
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCC
RYRVAHGGEAMRFDLVDFAAFDLFVLTRPAAQEDYGPAIKEAAAARHAAMSEDDRKQLAA
EEEECCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
NLTAGLPGAADGWSLDGVREQLALYDHISPDRLRQHLVDFLSEVVPEAEKLGLRLCCHPD
HHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHCCEEEEECCC
DPPFPLLGLPRIVSTEADYRFMLDAVDSPANGVTLCSGSLGVRPDNDLPGMAERLGPRIH
CCCCCCCCCCHHHCCCCCHHEEEHHCCCCCCCEEEECCCCCCCCCCCCCCHHHHCCCCEE
FVHLRNIRRQEPVDGLRRSFFEDEHLAGETDMVATIAALQTEEARRRAEGRTDWEIPMRP
EEEHHHCCCCCCHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DHGQDILDDIGRGGQPGYPAIGRLKGLAELRGIMTALAHPLHLERA
CCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]