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The map label for this gene is 158424343

Identifier: 158424343

GI number: 158424343

Start: 3087664

End: 3089433

Strand: Direct

Name: 158424343

Synonym: AZC_2719

Alternate gene names: NA

Gene position: 3087664-3089433 (Clockwise)

Preceding gene: 158424342

Following gene: 158424344

Centisome position: 57.5

GC content: 64.8

Gene sequence:

>1770_bases
ATGGCGCGCAAGCTCCCCAAGAAAGACGTGGTGATCATCGGCCTCGGCTGGACCGGATCGCTGCTCGCCCATGAACTCAC
GGACGCAGGTCTCGACGTTGTCGCGATCGAGCGTGGTCCATGGCGCGACACCTCAACCGACTTTTCGCCGACGCAGGATC
CCGATGAGCTGCGCTACGGCATCCGTCTGGACCTGTTCCTGCGGCCGGCGCAAGAAACCTTTACGTTACGGCACAACGTA
GCCCAGCAGGCGCTGCCCATCCGATGGCCGGGCGCCTTCATCGTCGGAAACGGCGTCGGCGGCGCCGGCGTGCACTGGAA
CGGCCACACCTGGCGCTTCCTGGAGACGGATTTCACGCTGAAATCCCACCTCACTCAACGTTATGGCGCCAGCGCCCTGC
CAGAGGACATGCAGATCGAGGACTGGGGCGTCACCTACGCCGACCTCGAGCCCTATTACGACAAGTTCGAATACATCGCC
GGCACGTCCGGCCGCGCCGGCAACATCCAGGGCAAGATGCAGGCGGGCGGCAATCCCTTCGAGGGCCCTCGCACACGGGA
CTACCCTCTGCCGCCGCTCAAGGACACCGCGCCCACGGCGCTGTTCGCGAAGACCGCGAGCGAGATGGGCTATCACGCAT
TCCCGCGCCCTGCGAGCAATGCCTCAGAGGCCTATGTGAACCCGCTCGGCATCGCCATGGGGCCCTGCACCTACTGCGGC
TTCTGCGAACGCTTCGGCTGCGGCAACTATTCCAAGGCCAGCCCGCAAGCGAACGTTCTGCCGGTGCTGATGCGCAAATC
CAATTTCAGCGTGCGCACCGAATGCGAGGTGCTGCACATCAACAAGCATCCCGGCGGCAATGTCGCGACGGGCGTGACCT
TCGTGGACAGCTCCGGCGAAGAATGGGACCAGCCCGCCGACATCGTGCTGGTGTGCGCCTACGGCCTGCACAACGTGCGG
ATGATGCTGCTCTCCGGCATCGGCCAGCCCTATGATCCGAAGACAGGCGAGGGTGTGGTCGGGCGCAATTATGCCTACCA
GTCCGCCGGTGCCGCCGGCCTGCTGTTCGAGGGTAAGCGCTTCAATCCCTTCGTCGGCGCCGGCTCGCTCGGCCAGTGCA
TCGACGACTTCAACGGCGACAATTTCGACCATGCCGGCCTCGGCTTCGTGGGCGGCGCCAGCATCACCACGTCGAACTAT
CATGGCCGCCCCATCGCCATGTCGGCCACCCGTGCCCCAGGTACGCCGGCCTGGGGTTCGGCGTGGAAGAAGCAGGTGGC
CTCCACCTATCAGAACACCTCGGCCGTGGCGGGCCAGGGCAGCGTCTATTCCTACCGCGACAAGTATCTGGACCTTGATC
CCGTCTACAAGGACAGGTTCGGGCGCCCGCTGCTGCGCATGACGTTCGACTGGCACGAGAACGAGAAGAAGATGACGCGC
TTCATCGCCCAGAAGTGCGCCGAGATCGGCAAGGCCATGGGCGCCAAGCATGTGACGCCCCGCTCCCTGCCCGACCACTT
CAACGTGGTGCCCTATCAGAGCACGCACAATACGGGCGGCGCCATCATGGGCGACAATCCCAAGCGCAGCGCGGTGAACC
GCTATCTGCAGAGCTGGGACGCCCACAACGTGTTCGTCATCGGCGCCTCGGCCTTCCCACAGAATGCCGGCTACAACCCC
ACGGGCACCGTGGGTGCGCTGGCGCTCTGGGCGGCGGATGCCATCCGCAACCAGTATCTCAAAAACCCCGGCCCCCTGGT
TCAGGCATAG

Upstream 100 bases:

>100_bases
GTCGGCCTGCAGGGTCGCGCCGGCTGGACGCCGGGTCGCTGATCGGACCCATCCCCTTCCCTCTCCCGGGCCGCCGCGCG
CGGACCGACAGGATAGAACG

Downstream 100 bases:

>100_bases
GTCCGCCCATGTCCAGCGTCCTCAGCCGCCTCTTCGCCTGTGCCTTCGGCCTTGCCGTGGCCGGAACCCCGCTTCTTGCC
CACGCCGACGGGCAGGACTT

Product: GMC oxidoreductase

Products: NA

Alternate protein names: GA 2-DH dehydrogenase subunit; GADH dehydrogenase subunit [H]

Number of amino acids: Translated: 589; Mature: 588

Protein sequence:

>589_residues
MARKLPKKDVVIIGLGWTGSLLAHELTDAGLDVVAIERGPWRDTSTDFSPTQDPDELRYGIRLDLFLRPAQETFTLRHNV
AQQALPIRWPGAFIVGNGVGGAGVHWNGHTWRFLETDFTLKSHLTQRYGASALPEDMQIEDWGVTYADLEPYYDKFEYIA
GTSGRAGNIQGKMQAGGNPFEGPRTRDYPLPPLKDTAPTALFAKTASEMGYHAFPRPASNASEAYVNPLGIAMGPCTYCG
FCERFGCGNYSKASPQANVLPVLMRKSNFSVRTECEVLHINKHPGGNVATGVTFVDSSGEEWDQPADIVLVCAYGLHNVR
MMLLSGIGQPYDPKTGEGVVGRNYAYQSAGAAGLLFEGKRFNPFVGAGSLGQCIDDFNGDNFDHAGLGFVGGASITTSNY
HGRPIAMSATRAPGTPAWGSAWKKQVASTYQNTSAVAGQGSVYSYRDKYLDLDPVYKDRFGRPLLRMTFDWHENEKKMTR
FIAQKCAEIGKAMGAKHVTPRSLPDHFNVVPYQSTHNTGGAIMGDNPKRSAVNRYLQSWDAHNVFVIGASAFPQNAGYNP
TGTVGALALWAADAIRNQYLKNPGPLVQA

Sequences:

>Translated_589_residues
MARKLPKKDVVIIGLGWTGSLLAHELTDAGLDVVAIERGPWRDTSTDFSPTQDPDELRYGIRLDLFLRPAQETFTLRHNV
AQQALPIRWPGAFIVGNGVGGAGVHWNGHTWRFLETDFTLKSHLTQRYGASALPEDMQIEDWGVTYADLEPYYDKFEYIA
GTSGRAGNIQGKMQAGGNPFEGPRTRDYPLPPLKDTAPTALFAKTASEMGYHAFPRPASNASEAYVNPLGIAMGPCTYCG
FCERFGCGNYSKASPQANVLPVLMRKSNFSVRTECEVLHINKHPGGNVATGVTFVDSSGEEWDQPADIVLVCAYGLHNVR
MMLLSGIGQPYDPKTGEGVVGRNYAYQSAGAAGLLFEGKRFNPFVGAGSLGQCIDDFNGDNFDHAGLGFVGGASITTSNY
HGRPIAMSATRAPGTPAWGSAWKKQVASTYQNTSAVAGQGSVYSYRDKYLDLDPVYKDRFGRPLLRMTFDWHENEKKMTR
FIAQKCAEIGKAMGAKHVTPRSLPDHFNVVPYQSTHNTGGAIMGDNPKRSAVNRYLQSWDAHNVFVIGASAFPQNAGYNP
TGTVGALALWAADAIRNQYLKNPGPLVQA
>Mature_588_residues
ARKLPKKDVVIIGLGWTGSLLAHELTDAGLDVVAIERGPWRDTSTDFSPTQDPDELRYGIRLDLFLRPAQETFTLRHNVA
QQALPIRWPGAFIVGNGVGGAGVHWNGHTWRFLETDFTLKSHLTQRYGASALPEDMQIEDWGVTYADLEPYYDKFEYIAG
TSGRAGNIQGKMQAGGNPFEGPRTRDYPLPPLKDTAPTALFAKTASEMGYHAFPRPASNASEAYVNPLGIAMGPCTYCGF
CERFGCGNYSKASPQANVLPVLMRKSNFSVRTECEVLHINKHPGGNVATGVTFVDSSGEEWDQPADIVLVCAYGLHNVRM
MLLSGIGQPYDPKTGEGVVGRNYAYQSAGAAGLLFEGKRFNPFVGAGSLGQCIDDFNGDNFDHAGLGFVGGASITTSNYH
GRPIAMSATRAPGTPAWGSAWKKQVASTYQNTSAVAGQGSVYSYRDKYLDLDPVYKDRFGRPLLRMTFDWHENEKKMTRF
IAQKCAEIGKAMGAKHVTPRSLPDHFNVVPYQSTHNTGGAIMGDNPKRSAVNRYLQSWDAHNVFVIGASAFPQNAGYNPT
GTVGALALWAADAIRNQYLKNPGPLVQA

Specific function: Part of the heterotrimer that catalyzes the conversion of D-gluconate to 2-dehydro-D-gluconate. This subunit functions as the dehydrogenase [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.3 [H]

Molecular weight: Translated: 64150; Mature: 64019

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKLPKKDVVIIGLGWTGSLLAHELTDAGLDVVAIERGPWRDTSTDFSPTQDPDELRYG
CCCCCCCCCEEEEEECCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHCC
IRLDLFLRPAQETFTLRHNVAQQALPIRWPGAFIVGNGVGGAGVHWNGHTWRFLETDFTL
EEEEEEECCCHHHHHHHHHHHHHCCCEECCCEEEEECCCCCCCEEECCCEEEEEECCHHH
KSHLTQRYGASALPEDMQIEDWGVTYADLEPYYDKFEYIAGTSGRAGNIQGKMQAGGNPF
HHHHHHHHCCCCCCCCCEECCCCCEEECCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCC
EGPRTRDYPLPPLKDTAPTALFAKTASEMGYHAFPRPASNASEAYVNPLGIAMGPCTYCG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCHHEECCHHHHH
FCERFGCGNYSKASPQANVLPVLMRKSNFSVRTECEVLHINKHPGGNVATGVTFVDSSGE
HHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEEEECCCCCCEEEEEEEECCCCC
EWDQPADIVLVCAYGLHNVRMMLLSGIGQPYDPKTGEGVVGRNYAYQSAGAAGLLFEGKR
CCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCEEEEECCC
FNPFVGAGSLGQCIDDFNGDNFDHAGLGFVGGASITTSNYHGRPIAMSATRAPGTPAWGS
CCCCCCCCCHHHHHHHCCCCCCCCCCCCEECCCEEEECCCCCCEEEEECCCCCCCCCHHH
AWKKQVASTYQNTSAVAGQGSVYSYRDKYLDLDPVYKDRFGRPLLRMTFDWHENEKKMTR
HHHHHHHHHHHCCHHCCCCCCEEEHHHCCCCCCCHHHHHCCCCEEEEEECCCCCHHHHHH
FIAQKCAEIGKAMGAKHVTPRSLPDHFNVVPYQSTHNTGGAIMGDNPKRSAVNRYLQSWD
HHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCEEECCCCHHHHHHHHHHCCC
AHNVFVIGASAFPQNAGYNPTGTVGALALWAADAIRNQYLKNPGPLVQA
CCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ARKLPKKDVVIIGLGWTGSLLAHELTDAGLDVVAIERGPWRDTSTDFSPTQDPDELRYG
CCCCCCCCEEEEEECCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHCC
IRLDLFLRPAQETFTLRHNVAQQALPIRWPGAFIVGNGVGGAGVHWNGHTWRFLETDFTL
EEEEEEECCCHHHHHHHHHHHHHCCCEECCCEEEEECCCCCCCEEECCCEEEEEECCHHH
KSHLTQRYGASALPEDMQIEDWGVTYADLEPYYDKFEYIAGTSGRAGNIQGKMQAGGNPF
HHHHHHHHCCCCCCCCCEECCCCCEEECCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCC
EGPRTRDYPLPPLKDTAPTALFAKTASEMGYHAFPRPASNASEAYVNPLGIAMGPCTYCG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCHHEECCHHHHH
FCERFGCGNYSKASPQANVLPVLMRKSNFSVRTECEVLHINKHPGGNVATGVTFVDSSGE
HHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEEEECCCCCCEEEEEEEECCCCC
EWDQPADIVLVCAYGLHNVRMMLLSGIGQPYDPKTGEGVVGRNYAYQSAGAAGLLFEGKR
CCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCEEEEECCC
FNPFVGAGSLGQCIDDFNGDNFDHAGLGFVGGASITTSNYHGRPIAMSATRAPGTPAWGS
CCCCCCCCCHHHHHHHCCCCCCCCCCCCEECCCEEEECCCCCCEEEEECCCCCCCCCHHH
AWKKQVASTYQNTSAVAGQGSVYSYRDKYLDLDPVYKDRFGRPLLRMTFDWHENEKKMTR
HHHHHHHHHHHCCHHCCCCCCEEEHHHCCCCCCCHHHHHCCCCEEEEEECCCCCHHHHHH
FIAQKCAEIGKAMGAKHVTPRSLPDHFNVVPYQSTHNTGGAIMGDNPKRSAVNRYLQSWD
HHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCEEECCCCHHHHHHHHHHCCC
AHNVFVIGASAFPQNAGYNPTGTVGALALWAADAIRNQYLKNPGPLVQA
CCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9352901 [H]