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The map label for this gene is siaT [H]

Identifier: 158424313

GI number: 158424313

Start: 3047491

End: 3049386

Strand: Reverse

Name: siaT [H]

Synonym: AZC_2689

Alternate gene names: 158424313

Gene position: 3049386-3047491 (Counterclockwise)

Preceding gene: 158424314

Following gene: 158424312

Centisome position: 56.79

GC content: 67.62

Gene sequence:

>1896_bases
TTGATCGGAGGCGCCATGTCCGGCTCCTTGTCCCCAACGGCTGCCGAGAACGCGGCAGCCGCCCGGTCGGCTGCGTCCGG
CTTCGGGCGGCTGGACGCGGCCTTCTTCGGCCTCATCGAGCATGTGGCGGCGGCCATCGTCCTCGTGGAGGTGGGCGTCC
TGTTCGCGGGCGTCGTGGCGCGCTACGTCTTCCACGCGCCCCTCGTCTGGTCCGATGAACTCGCCTCCATCCTCTTCCTG
TGGCTCTCCATGCTCGGCGCGGTGGTGGCGCTGCGCCGGGGCGAGCACATGCGCATGACCGGCTGCCTCGGCCTCGCCGG
CCCGCAGACCCGCGCCGTGCTGGAAGCACTCGCCATCCTCGTGCCGCTGGGCTTCCTCGGCCTCGTGCTGCACCCGGCGC
TGGATTATGCCTCGGAGGAGCGCTTCATCGTCACGCCGGCGCTGGAGATCAGCAATGTCTGGCGGGCGGCGGCCATTCCG
GTCGGCCTCAGCCTCATGGTGCTGGCGTGCTTGGCGCGGCTCGCCCGCGCGGCGTCCTTCAAAGCGGTGGTGATCGCTCT
GGGTCTCACGGCGGGGCTGATGGTGGCCTTCTATCTGCTCGGGCCGGTGCTGAAGCCGCTCGGCCAGATCAATCTCATCA
TCTTCTTCGTGGGCGTGGTGGCGCTCTGCGTGTTCGCCGGCGTTCCCATTGCCTTTGCCTTCGCGCTCGCCACCTTCGGT
TATCTCGCGCTCACCACCCGCACGCCCATGCTGGTGATGGTGGGGCGGCTCGATGAGGGCATGAGCCACCTCATCCTACT
CGCCGTGCCGCTGTTCATCTTCCTCGGCGCGCTCATCGAGATGACGGGCATGGCCAAGGCCATGATCGCCTTTCTGGCGA
GCCTGCTCGGCCATGTGCGCGGTGGCCTCTCTTATGTGCTCATCGGCGCCATGTATCTGGTCTCGGGCATCTCCGGCTCC
AAGATCGCCGACATGGCCGCCATCGCGCCCATTCTCTTCCCGGAGATGAAGGCGCGCGGGGCGAAGGAGGGCGATCTCGT
GGCGCTGCTCTCCGCCACGGGGGCGCAGACGGAGACCATTCCACCCTCCATCGTGCTCATCACCATCGGCTCGGTGACGG
GCGTCTCCATCGCCGCGCTGTTCACCGGCGGCATGGTGCCGGCCCTCGTGCTCGGCCTGTGCCTGTGCACCGTGGTCTGG
CGGCGTTATCGTAACGAGGATCTGAGCCACATCCGCAAGCCGGCGTGGCGGGAGATCGGCAAGCTCGCCATCGTCGCTCT
GCCGGCTATCGCGCTGCCCTTCGTCATCCGCGCGGCGGTGGTGGAGGGGGTGGCAACGGCCACCGAGGTCTCCACCATAG
GCATCGTCTATGCGGTGCTGGCGGGCCTCCTCATCTACCGGCGCTTCGACTGGCGGCGCATCCAGCCGATGCTCATCGAG
ACGGCCTCGCTGACCGGCGCCATCATCTTCATCGTCGGCTGCGCCACAGCTATGGCCTGGGGCCTCACCCAGTCCGGCTT
CTCCCGCAATCTGGCGCAGGCCATGGCGGGGATCCCGGGCGGCGCCTATGGCTTCCTCGCCGTCTCCATCGTGGCCTTCA
TCATCCTCGGCAGCGTGCTGGAGGGCATTCCGGCCATCGTACTGTTCGGCCCGCTGCTGTTCCCCATCGCCAAGGCGGCG
GGGGTGCATGAGGTGCACTATGCGATGGTGGTGATCTTCGCCATGGGCATCGGCCTCTTCGCCCCACCGTTCGGCGTTGG
CTATTACGGCGCCTGCGCCATTTCCAAGATCCATCCGGACGAGGGCCTCAAGCACATCTGGGGCTATGTGGCGGCGCTGC
TCGTCGGCCTCGTCCTGGTCGCGGCCATTCCGTGGCTGTCCATCGGCTTCCTGTAA

Upstream 100 bases:

>100_bases
GGCTTCTATGTTGAGTGGAAGGGCCGCTTCGGAGACGAGGTGTGGGGCCTTCTGGAAGGCGCCGTCGGCAAGCTCGCCTG
AGTTCCCTTTGACCTGACGT

Downstream 100 bases:

>100_bases
TCTTCCGATCAATAGAGGTGCGTCATGAGCCGGTTTTTCGGCGACATCCGGCAGGCCGGATATGTGGTCAACGATATCGA
AGCGGCGATGGATTACTGGA

Product: tripartite ATP-independent periplasmic transporter

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MIGGAMSGSLSPTAAENAAAARSAASGFGRLDAAFFGLIEHVAAAIVLVEVGVLFAGVVARYVFHAPLVWSDELASILFL
WLSMLGAVVALRRGEHMRMTGCLGLAGPQTRAVLEALAILVPLGFLGLVLHPALDYASEERFIVTPALEISNVWRAAAIP
VGLSLMVLACLARLARAASFKAVVIALGLTAGLMVAFYLLGPVLKPLGQINLIIFFVGVVALCVFAGVPIAFAFALATFG
YLALTTRTPMLVMVGRLDEGMSHLILLAVPLFIFLGALIEMTGMAKAMIAFLASLLGHVRGGLSYVLIGAMYLVSGISGS
KIADMAAIAPILFPEMKARGAKEGDLVALLSATGAQTETIPPSIVLITIGSVTGVSIAALFTGGMVPALVLGLCLCTVVW
RRYRNEDLSHIRKPAWREIGKLAIVALPAIALPFVIRAAVVEGVATATEVSTIGIVYAVLAGLLIYRRFDWRRIQPMLIE
TASLTGAIIFIVGCATAMAWGLTQSGFSRNLAQAMAGIPGGAYGFLAVSIVAFIILGSVLEGIPAIVLFGPLLFPIAKAA
GVHEVHYAMVVIFAMGIGLFAPPFGVGYYGACAISKIHPDEGLKHIWGYVAALLVGLVLVAAIPWLSIGFL

Sequences:

>Translated_631_residues
MIGGAMSGSLSPTAAENAAAARSAASGFGRLDAAFFGLIEHVAAAIVLVEVGVLFAGVVARYVFHAPLVWSDELASILFL
WLSMLGAVVALRRGEHMRMTGCLGLAGPQTRAVLEALAILVPLGFLGLVLHPALDYASEERFIVTPALEISNVWRAAAIP
VGLSLMVLACLARLARAASFKAVVIALGLTAGLMVAFYLLGPVLKPLGQINLIIFFVGVVALCVFAGVPIAFAFALATFG
YLALTTRTPMLVMVGRLDEGMSHLILLAVPLFIFLGALIEMTGMAKAMIAFLASLLGHVRGGLSYVLIGAMYLVSGISGS
KIADMAAIAPILFPEMKARGAKEGDLVALLSATGAQTETIPPSIVLITIGSVTGVSIAALFTGGMVPALVLGLCLCTVVW
RRYRNEDLSHIRKPAWREIGKLAIVALPAIALPFVIRAAVVEGVATATEVSTIGIVYAVLAGLLIYRRFDWRRIQPMLIE
TASLTGAIIFIVGCATAMAWGLTQSGFSRNLAQAMAGIPGGAYGFLAVSIVAFIILGSVLEGIPAIVLFGPLLFPIAKAA
GVHEVHYAMVVIFAMGIGLFAPPFGVGYYGACAISKIHPDEGLKHIWGYVAALLVGLVLVAAIPWLSIGFL
>Mature_631_residues
MIGGAMSGSLSPTAAENAAAARSAASGFGRLDAAFFGLIEHVAAAIVLVEVGVLFAGVVARYVFHAPLVWSDELASILFL
WLSMLGAVVALRRGEHMRMTGCLGLAGPQTRAVLEALAILVPLGFLGLVLHPALDYASEERFIVTPALEISNVWRAAAIP
VGLSLMVLACLARLARAASFKAVVIALGLTAGLMVAFYLLGPVLKPLGQINLIIFFVGVVALCVFAGVPIAFAFALATFG
YLALTTRTPMLVMVGRLDEGMSHLILLAVPLFIFLGALIEMTGMAKAMIAFLASLLGHVRGGLSYVLIGAMYLVSGISGS
KIADMAAIAPILFPEMKARGAKEGDLVALLSATGAQTETIPPSIVLITIGSVTGVSIAALFTGGMVPALVLGLCLCTVVW
RRYRNEDLSHIRKPAWREIGKLAIVALPAIALPFVIRAAVVEGVATATEVSTIGIVYAVLAGLLIYRRFDWRRIQPMLIE
TASLTGAIIFIVGCATAMAWGLTQSGFSRNLAQAMAGIPGGAYGFLAVSIVAFIILGSVLEGIPAIVLFGPLLFPIAKAA
GVHEVHYAMVVIFAMGIGLFAPPFGVGYYGACAISKIHPDEGLKHIWGYVAALLVGLVLVAAIPWLSIGFL

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=394, Percent_Identity=27.1573604060914, Blast_Score=134, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 65882; Mature: 65882

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGGAMSGSLSPTAAENAAAARSAASGFGRLDAAFFGLIEHVAAAIVLVEVGVLFAGVVA
CCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYVFHAPLVWSDELASILFLWLSMLGAVVALRRGEHMRMTGCLGLAGPQTRAVLEALAIL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHCCCCCCCHHHHHHHHHHHH
VPLGFLGLVLHPALDYASEERFIVTPALEISNVWRAAAIPVGLSLMVLACLARLARAASF
HHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAVVIALGLTAGLMVAFYLLGPVLKPLGQINLIIFFVGVVALCVFAGVPIAFAFALATFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
YLALTTRTPMLVMVGRLDEGMSHLILLAVPLFIFLGALIEMTGMAKAMIAFLASLLGHVR
HHHHHCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGLSYVLIGAMYLVSGISGSKIADMAAIAPILFPEMKARGAKEGDLVALLSATGAQTETI
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCC
PPSIVLITIGSVTGVSIAALFTGGMVPALVLGLCLCTVVWRRYRNEDLSHIRKPAWREIG
CCCEEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHH
KLAIVALPAIALPFVIRAAVVEGVATATEVSTIGIVYAVLAGLLIYRRFDWRRIQPMLIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHH
TASLTGAIIFIVGCATAMAWGLTQSGFSRNLAQAMAGIPGGAYGFLAVSIVAFIILGSVL
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
EGIPAIVLFGPLLFPIAKAAGVHEVHYAMVVIFAMGIGLFAPPFGVGYYGACAISKIHPD
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCH
EGLKHIWGYVAALLVGLVLVAAIPWLSIGFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIGGAMSGSLSPTAAENAAAARSAASGFGRLDAAFFGLIEHVAAAIVLVEVGVLFAGVVA
CCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYVFHAPLVWSDELASILFLWLSMLGAVVALRRGEHMRMTGCLGLAGPQTRAVLEALAIL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHCCCCCCCHHHHHHHHHHHH
VPLGFLGLVLHPALDYASEERFIVTPALEISNVWRAAAIPVGLSLMVLACLARLARAASF
HHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAVVIALGLTAGLMVAFYLLGPVLKPLGQINLIIFFVGVVALCVFAGVPIAFAFALATFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
YLALTTRTPMLVMVGRLDEGMSHLILLAVPLFIFLGALIEMTGMAKAMIAFLASLLGHVR
HHHHHCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGLSYVLIGAMYLVSGISGSKIADMAAIAPILFPEMKARGAKEGDLVALLSATGAQTETI
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCC
PPSIVLITIGSVTGVSIAALFTGGMVPALVLGLCLCTVVWRRYRNEDLSHIRKPAWREIG
CCCEEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHH
KLAIVALPAIALPFVIRAAVVEGVATATEVSTIGIVYAVLAGLLIYRRFDWRRIQPMLIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHH
TASLTGAIIFIVGCATAMAWGLTQSGFSRNLAQAMAGIPGGAYGFLAVSIVAFIILGSVL
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
EGIPAIVLFGPLLFPIAKAAGVHEVHYAMVVIFAMGIGLFAPPFGVGYYGACAISKIHPD
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCH
EGLKHIWGYVAALLVGLVLVAAIPWLSIGFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]