Click here to switch to the map view.

The map label for this gene is dapA2 [H]

Identifier: 158424309

GI number: 158424309

Start: 3043408

End: 3044355

Strand: Direct

Name: dapA2 [H]

Synonym: AZC_2685

Alternate gene names: 158424309

Gene position: 3043408-3044355 (Clockwise)

Preceding gene: 158424308

Following gene: 158424315

Centisome position: 56.68

GC content: 69.73

Gene sequence:

>948_bases
ATGACTGAAACCTTCGTCCAGCGCCTGTCCGGCATTCATGCGGCCACCGTGGTGCCCATGCGCGCCGACTTCTCCATGGA
CGAGGATGCGCTCGCCGCCCACATCGGTGCCGTGACCCGCGTAAAGGGCATTCGTGGCCTGCTCATCAACGGCCATGCGG
GCGAGAACTTCGTGCTGTCGCTGGCCGAGAAGCGCCGGGTGGTGGAAATCGCCCGCACGGTCGCCCCGAAGGACTGCCTG
CTGGTCTCGGGCGTGAACCACGAATCGAGCCTGGAGGCCGCCCGCGAGGCAGCGGAGATGGCGGCGGCCGGGGCGGATGG
CCTTCTGGTCTTTCCACCCAACAGCTGGGCGCTCGGCCATGCGGACGCATGCACGCTGATGCACCACAAGATGATTGCGG
ACGCGACGGCGCTGCCGCTCATGCTTTATGGCGCACCTGTGGGCGCGGGGGCGATGTCCTATTCGTCCGAGGTGCTCTCC
CGCCTCATCGACGATCCGCGCTTCGTCGCCATCAAGGATGGCAGCTGGGAAGTCGCGGCCTATGAGGAGAACCTGCGCCT
GATCCAGTCCCGCCGCCCGGGCTTCGCGGTGCTCGGCTCGGGCGACGAGCACCTTCTGACCAGCTACGTGATCGGCAGCG
CCGGCAGCCAGGTGAGCCTTGCGGCCGTCGTGCCCGAGCTGGTGGTCGCCCTGTGGGACGCCGCGGCGGCGGGCGACTGG
GCAAGAGCCCGGCAGGTGCACGAGCAGCTCTATCCGCTCTCCGTCGCCATCTATCGCGACGCGCCGGGCGGTCGCGCCAC
CGCGCGGCTGAAGACCTGCCTCAAGCTGCTCGGCCGGCTCGGCAATGACGTGGTGCGTCCGCCCCAGCCGTCCTGCGACG
CGCGGGAGAACGCAGCCCTCTCGGCGGCGCTCAGGGCGGCAGGCGTGGAGGTGCCGGTGGCGGCCTGA

Upstream 100 bases:

>100_bases
GCCCGCCTGCTGGCGGACCGCATTCTGGGCCGCGAACCCGCTTTGCCCTTGTTCCCCATCGATCGTTTGCTCGCGTCAAG
CGCCATTTCCGAGGCCCGCA

Downstream 100 bases:

>100_bases
GCCCTCTCAGCCGCCGTGGAGCAGGCGCTCGAACAGGTCTGGCGTGCCCATCTGGCCGCCCTTCAGCATCAGTTCGAGGT
CGTCCAGAGCCGGGACGTCG

Product: dihydrodipicolinate synthetase

Products: NA

Alternate protein names: DHDPS 2 [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MTETFVQRLSGIHAATVVPMRADFSMDEDALAAHIGAVTRVKGIRGLLINGHAGENFVLSLAEKRRVVEIARTVAPKDCL
LVSGVNHESSLEAAREAAEMAAAGADGLLVFPPNSWALGHADACTLMHHKMIADATALPLMLYGAPVGAGAMSYSSEVLS
RLIDDPRFVAIKDGSWEVAAYEENLRLIQSRRPGFAVLGSGDEHLLTSYVIGSAGSQVSLAAVVPELVVALWDAAAAGDW
ARARQVHEQLYPLSVAIYRDAPGGRATARLKTCLKLLGRLGNDVVRPPQPSCDARENAALSAALRAAGVEVPVAA

Sequences:

>Translated_315_residues
MTETFVQRLSGIHAATVVPMRADFSMDEDALAAHIGAVTRVKGIRGLLINGHAGENFVLSLAEKRRVVEIARTVAPKDCL
LVSGVNHESSLEAAREAAEMAAAGADGLLVFPPNSWALGHADACTLMHHKMIADATALPLMLYGAPVGAGAMSYSSEVLS
RLIDDPRFVAIKDGSWEVAAYEENLRLIQSRRPGFAVLGSGDEHLLTSYVIGSAGSQVSLAAVVPELVVALWDAAAAGDW
ARARQVHEQLYPLSVAIYRDAPGGRATARLKTCLKLLGRLGNDVVRPPQPSCDARENAALSAALRAAGVEVPVAA
>Mature_314_residues
TETFVQRLSGIHAATVVPMRADFSMDEDALAAHIGAVTRVKGIRGLLINGHAGENFVLSLAEKRRVVEIARTVAPKDCLL
VSGVNHESSLEAAREAAEMAAAGADGLLVFPPNSWALGHADACTLMHHKMIADATALPLMLYGAPVGAGAMSYSSEVLSR
LIDDPRFVAIKDGSWEVAAYEENLRLIQSRRPGFAVLGSGDEHLLTSYVIGSAGSQVSLAAVVPELVVALWDAAAAGDWA
RARQVHEQLYPLSVAIYRDAPGGRATARLKTCLKLLGRLGNDVVRPPQPSCDARENAALSAALRAAGVEVPVAA

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=292, Percent_Identity=26.3698630136986, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI13540533, Length=215, Percent_Identity=27.4418604651163, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI87082415, Length=254, Percent_Identity=28.3464566929134, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786463, Length=292, Percent_Identity=25.6849315068493, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1789620, Length=243, Percent_Identity=24.2798353909465, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 33199; Mature: 33068

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETFVQRLSGIHAATVVPMRADFSMDEDALAAHIGAVTRVKGIRGLLINGHAGENFVLS
CCHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHH
LAEKRRVVEIARTVAPKDCLLVSGVNHESSLEAAREAAEMAAAGADGLLVFPPNSWALGH
HHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCC
ADACTLMHHKMIADATALPLMLYGAPVGAGAMSYSSEVLSRLIDDPRFVAIKDGSWEVAA
CHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCEEEEE
YEENLRLIQSRRPGFAVLGSGDEHLLTSYVIGSAGSQVSLAAVVPELVVALWDAAAAGDW
EHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHH
ARARQVHEQLYPLSVAIYRDAPGGRATARLKTCLKLLGRLGNDVVRPPQPSCDARENAAL
HHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
SAALRAAGVEVPVAA
HHHHHHCCCCCCCCC
>Mature Secondary Structure 
TETFVQRLSGIHAATVVPMRADFSMDEDALAAHIGAVTRVKGIRGLLINGHAGENFVLS
CHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHH
LAEKRRVVEIARTVAPKDCLLVSGVNHESSLEAAREAAEMAAAGADGLLVFPPNSWALGH
HHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCC
ADACTLMHHKMIADATALPLMLYGAPVGAGAMSYSSEVLSRLIDDPRFVAIKDGSWEVAA
CHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCEEEEE
YEENLRLIQSRRPGFAVLGSGDEHLLTSYVIGSAGSQVSLAAVVPELVVALWDAAAAGDW
EHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHH
ARARQVHEQLYPLSVAIYRDAPGGRATARLKTCLKLLGRLGNDVVRPPQPSCDARENAAL
HHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
SAALRAAGVEVPVAA
HHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]