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The map label for this gene is lysR [H]

Identifier: 158424294

GI number: 158424294

Start: 3028864

End: 3029781

Strand: Direct

Name: lysR [H]

Synonym: AZC_2670

Alternate gene names: 158424294

Gene position: 3028864-3029781 (Clockwise)

Preceding gene: 158424289

Following gene: 158424296

Centisome position: 56.41

GC content: 64.05

Gene sequence:

>918_bases
ATGGACCAGTTGGCGGCAATGCGCGCCTTCGTGCGGGTGGTGGAGAGCGGCAGCTTCACCCGCGCGGCGGACATTCTGGC
CCTGCCCAAGGCCACGCTCTCGAAACAGATCCAGCAGTTGGAGACGCATCTCTCGACTCGCCTGCTCCATCGCACCACGC
GCCAGGTGACGGTGACGCCAGACGGCGCCGCTTATTATGAACGCGCGCTCGCCATCCTTACGGACGTGGACGAACTGGAC
GGCTCACTGTCCACCAACCTGACCTGCCCGCGCGGACGCCTGCGCATCGATATTTCGCCCTCGCTCGCCACTGGCATCCT
GATGCCGGCGCTGCCCGACTTCTTCTCCCGCTATCCGGAGATTCACATCGACATCGGCTGCACCGACCGGCCGGTGGACC
TGGTGGGCGAAAATGTCGACTGCGTGATCCGGGTCGGCGAAATCCGCAACTCCAGCCTGATCGCGCGGCGGATCGGAGAA
CTCAATTTCGCCGCTGCGGCCGCGCCATCCTATATCGCGCGCCACGGGGAAATCCAGCACCCGAAGGATTTTGAGAAGGA
CCATGTGATGGTGCGCTATTTCAGCGCCACGACCGCCCATTATTATGCCTTCGACTTCATTCGCGACGCGGAGGAGGTCG
AGGTTCTGGGGCGCTACAGTGTGGCCCTGAACGACGGCAATGCCTATGTATCGGCTGGTCTTGCCGGCCTTGGGGTGATC
CTGTGTCCCATCTTCATGATGCAGGAGCACCTCGACGCCGGGACGCTGGTGCGCGTGCTGCCCGAATGGCACACGCAGCC
GATGCCCATCCACGTGGTCTACCCGCCCAGCCGCCACATATCGAACCGCCTGCGCGTGTTCGTGGACTGGGTGGCGGAAC
TGTTCGCCCGCTCGACACGGGCCCGTGCAGCCACCTGA

Upstream 100 bases:

>100_bases
TGCGAAGACCCTATTTTATCCTTGCACCGTTGATAAACAGGCCAATCGGGAACTCATTATTCACGTCTGGAGACAATGAG
CCCCAAAGAGGACGCGGCAC

Downstream 100 bases:

>100_bases
AAGCCGGCGGGTGCCGTATCCGATTTCCTATGGGTTCAGGTGCTCCACCAGCATGTCGCGGAACTTCTTGGCCGCCGGGG
ACAGCCGCGAGGTGCGGCGC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MDQLAAMRAFVRVVESGSFTRAADILALPKATLSKQIQQLETHLSTRLLHRTTRQVTVTPDGAAYYERALAILTDVDELD
GSLSTNLTCPRGRLRIDISPSLATGILMPALPDFFSRYPEIHIDIGCTDRPVDLVGENVDCVIRVGEIRNSSLIARRIGE
LNFAAAAAPSYIARHGEIQHPKDFEKDHVMVRYFSATTAHYYAFDFIRDAEEVEVLGRYSVALNDGNAYVSAGLAGLGVI
LCPIFMMQEHLDAGTLVRVLPEWHTQPMPIHVVYPPSRHISNRLRVFVDWVAELFARSTRARAAT

Sequences:

>Translated_305_residues
MDQLAAMRAFVRVVESGSFTRAADILALPKATLSKQIQQLETHLSTRLLHRTTRQVTVTPDGAAYYERALAILTDVDELD
GSLSTNLTCPRGRLRIDISPSLATGILMPALPDFFSRYPEIHIDIGCTDRPVDLVGENVDCVIRVGEIRNSSLIARRIGE
LNFAAAAAPSYIARHGEIQHPKDFEKDHVMVRYFSATTAHYYAFDFIRDAEEVEVLGRYSVALNDGNAYVSAGLAGLGVI
LCPIFMMQEHLDAGTLVRVLPEWHTQPMPIHVVYPPSRHISNRLRVFVDWVAELFARSTRARAAT
>Mature_305_residues
MDQLAAMRAFVRVVESGSFTRAADILALPKATLSKQIQQLETHLSTRLLHRTTRQVTVTPDGAAYYERALAILTDVDELD
GSLSTNLTCPRGRLRIDISPSLATGILMPALPDFFSRYPEIHIDIGCTDRPVDLVGENVDCVIRVGEIRNSSLIARRIGE
LNFAAAAAPSYIARHGEIQHPKDFEKDHVMVRYFSATTAHYYAFDFIRDAEEVEVLGRYSVALNDGNAYVSAGLAGLGVI
LCPIFMMQEHLDAGTLVRVLPEWHTQPMPIHVVYPPSRHISNRLRVFVDWVAELFARSTRARAAT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693193, Length=294, Percent_Identity=40.8163265306122, Blast_Score=237, Evalue=8e-64,
Organism=Escherichia coli, GI1786401, Length=289, Percent_Identity=31.8339100346021, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1787128, Length=283, Percent_Identity=30.3886925795053, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1789639, Length=307, Percent_Identity=27.0358306188925, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789440, Length=286, Percent_Identity=31.1188811188811, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI87081978, Length=296, Percent_Identity=33.445945945946, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1787589, Length=291, Percent_Identity=30.2405498281787, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1789173, Length=294, Percent_Identity=25.1700680272109, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1786448, Length=291, Percent_Identity=24.7422680412371, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI157672245, Length=116, Percent_Identity=33.6206896551724, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788706, Length=175, Percent_Identity=29.1428571428571, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788481, Length=298, Percent_Identity=24.496644295302, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI145693105, Length=154, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787601, Length=142, Percent_Identity=26.7605633802817, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33942; Mature: 33942

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQLAAMRAFVRVVESGSFTRAADILALPKATLSKQIQQLETHLSTRLLHRTTRQVTVTP
CCHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
DGAAYYERALAILTDVDELDGSLSTNLTCPRGRLRIDISPSLATGILMPALPDFFSRYPE
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCE
IHIDIGCTDRPVDLVGENVDCVIRVGEIRNSSLIARRIGELNFAAAAAPSYIARHGEIQH
EEEEECCCCCCHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCHHHHCCHHHHHHCCCCCC
PKDFEKDHVMVRYFSATTAHYYAFDFIRDAEEVEVLGRYSVALNDGNAYVSAGLAGLGVI
CCCCCCCCEEEEEEEHHHHHHHHHHHHHCHHHHHHHEEEEEEEECCCEEEHHHHHHHHHH
LCPIFMMQEHLDAGTLVRVLPEWHTQPMPIHVVYPPSRHISNRLRVFVDWVAELFARSTR
HHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
ARAAT
HCCCC
>Mature Secondary Structure
MDQLAAMRAFVRVVESGSFTRAADILALPKATLSKQIQQLETHLSTRLLHRTTRQVTVTP
CCHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
DGAAYYERALAILTDVDELDGSLSTNLTCPRGRLRIDISPSLATGILMPALPDFFSRYPE
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCE
IHIDIGCTDRPVDLVGENVDCVIRVGEIRNSSLIARRIGELNFAAAAAPSYIARHGEIQH
EEEEECCCCCCHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCHHHHCCHHHHHHCCCCCC
PKDFEKDHVMVRYFSATTAHYYAFDFIRDAEEVEVLGRYSVALNDGNAYVSAGLAGLGVI
CCCCCCCCEEEEEEEHHHHHHHHHHHHHCHHHHHHHEEEEEEEECCCEEEHHHHHHHHHH
LCPIFMMQEHLDAGTLVRVLPEWHTQPMPIHVVYPPSRHISNRLRVFVDWVAELFARSTR
HHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
ARAAT
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]