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The map label for this gene is caiD [C]

Identifier: 158424125

GI number: 158424125

Start: 2835662

End: 2836447

Strand: Direct

Name: caiD [C]

Synonym: AZC_2501

Alternate gene names: 158424125

Gene position: 2835662-2836447 (Clockwise)

Preceding gene: 158424124

Following gene: 158424126

Centisome position: 52.81

GC content: 70.99

Gene sequence:

>786_bases
GTGAGCGCCACCCTTCTCTATGAGGCGACGGAAGGTCTCGCCCGCATCACCATCGCGCAGGACGCGAAGATGAATGCCAT
GACCTTCGAGATGTGGTCGGCCCTGCCCGGCCTCATCTCGCGCGCGGCCGCCGATCCCGCCATCCGCGCCATCGTGCTCA
CGGGTGCCGGCGAGAAGGCCTTCTGCGCCGGGGCCGATATCTCCCAGTTCGGCGCGCGGCGTTCCGATCCGGAGGCGGTC
GCAGCCTATGACCATGCGGTGGCGGCCGGCATGACCGCCCTCGCCGGGGCTGAGAAGCCGACGGTGGCGCTCATCAGGGG
CATCTGCTTCGGCGGCGGCTTCGGCCTCGCGCTCGCCTGCGACATCCGCCTCGCCCGCGCCGACGCCCGCTTCCGCGTGC
CAGCGGCACGGCTCGGGCTCGGCTATGGCTATGAAGGCGTGAAACTCATCAGCCGCAAGCTGGGGCCAGACGCCACGGCC
GACATCCTCTTCTCCGCCCGCATCCTCGATGCCGCGGAGGCCGAACGCCTCGGCGTCGTGGCGCGGGCCTGGGCGGCAGA
GGCCTTCGAGACCGAAAGCGCGGCCTATCTCGGCCAGATCGCCGCCAATGCGCCGCTGACGCTTGTGGCGGCCAAGCGCG
CGCTGGTGGAACTCGCCCGCCCGGAAGCTGAGCGAGACCTCGACGCGGTGGCCGCGCGCGTCGCGGCCTGCTTTGCCAGC
GCCGACTATCGCGAGGGTCAGGCTGCCTTCAAGGAGAAGAGACCGCCCCGCTTTACCGGCGCCTGA

Upstream 100 bases:

>100_bases
TCGCCCCGCTCTCGGACAAGGGCGCGGACGGCGATGCCATCCTCGCCGAAATCGGCCTCGACGCCGGCCGCATCGCCGCA
CTCCGGGCGGAGGGCATCCT

Downstream 100 bases:

>100_bases
GCGCCAGCCTTTCCCACGCCGTTCCGTTCGTTGCGTCCCCCAATCAAAAATCCAGAGGACCAGGACATGCATCGCAGGAC
GTTTCTCGCCGGACTTTCGG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MSATLLYEATEGLARITIAQDAKMNAMTFEMWSALPGLISRAAADPAIRAIVLTGAGEKAFCAGADISQFGARRSDPEAV
AAYDHAVAAGMTALAGAEKPTVALIRGICFGGGFGLALACDIRLARADARFRVPAARLGLGYGYEGVKLISRKLGPDATA
DILFSARILDAAEAERLGVVARAWAAEAFETESAAYLGQIAANAPLTLVAAKRALVELARPEAERDLDAVAARVAACFAS
ADYREGQAAFKEKRPPRFTGA

Sequences:

>Translated_261_residues
MSATLLYEATEGLARITIAQDAKMNAMTFEMWSALPGLISRAAADPAIRAIVLTGAGEKAFCAGADISQFGARRSDPEAV
AAYDHAVAAGMTALAGAEKPTVALIRGICFGGGFGLALACDIRLARADARFRVPAARLGLGYGYEGVKLISRKLGPDATA
DILFSARILDAAEAERLGVVARAWAAEAFETESAAYLGQIAANAPLTLVAAKRALVELARPEAERDLDAVAARVAACFAS
ADYREGQAAFKEKRPPRFTGA
>Mature_260_residues
SATLLYEATEGLARITIAQDAKMNAMTFEMWSALPGLISRAAADPAIRAIVLTGAGEKAFCAGADISQFGARRSDPEAVA
AYDHAVAAGMTALAGAEKPTVALIRGICFGGGFGLALACDIRLARADARFRVPAARLGLGYGYEGVKLISRKLGPDATAD
ILFSARILDAAEAERLGVVARAWAAEAFETESAAYLGQIAANAPLTLVAAKRALVELARPEAERDLDAVAARVAACFASA
DYREGQAAFKEKRPPRFTGA

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=246, Percent_Identity=28.4552845528455, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI68989263, Length=187, Percent_Identity=33.1550802139037, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI4502327, Length=265, Percent_Identity=30.5660377358491, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI70995211, Length=257, Percent_Identity=24.5136186770428, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI20127408, Length=162, Percent_Identity=29.0123456790123, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI37594469, Length=134, Percent_Identity=32.8358208955224, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI37594471, Length=134, Percent_Identity=32.8358208955224, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI221142681, Length=268, Percent_Identity=31.7164179104478, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87082183, Length=218, Percent_Identity=27.5229357798165, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788597, Length=253, Percent_Identity=28.4584980237154, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787659, Length=249, Percent_Identity=28.9156626506024, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787660, Length=270, Percent_Identity=29.6296296296296, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1788682, Length=184, Percent_Identity=30.9782608695652, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790281, Length=167, Percent_Identity=30.5389221556886, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=253, Percent_Identity=30.8300395256917, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17554946, Length=248, Percent_Identity=28.6290322580645, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17536985, Length=226, Percent_Identity=30.5309734513274, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17540714, Length=236, Percent_Identity=25.8474576271186, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17534483, Length=258, Percent_Identity=24.8062015503876, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17558304, Length=164, Percent_Identity=28.0487804878049, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI20129971, Length=249, Percent_Identity=29.718875502008, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24653477, Length=249, Percent_Identity=29.718875502008, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24653139, Length=262, Percent_Identity=28.6259541984733, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI19920382, Length=259, Percent_Identity=25.0965250965251, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI19922422, Length=258, Percent_Identity=24.031007751938, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19921000, Length=133, Percent_Identity=30.8270676691729, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24583077, Length=133, Percent_Identity=30.8270676691729, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24583079, Length=133, Percent_Identity=30.8270676691729, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 27206; Mature: 27075

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATLLYEATEGLARITIAQDAKMNAMTFEMWSALPGLISRAAADPAIRAIVLTGAGEKA
CCCEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCE
FCAGADISQFGARRSDPEAVAAYDHAVAAGMTALAGAEKPTVALIRGICFGGGFGLALAC
EECCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEE
DIRLARADARFRVPAARLGLGYGYEGVKLISRKLGPDATADILFSARILDAAEAERLGVV
EEEEECCCCCEECCHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
ARAWAAEAFETESAAYLGQIAANAPLTLVAAKRALVELARPEAERDLDAVAARVAACFAS
HHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ADYREGQAAFKEKRPPRFTGA
CCCCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SATLLYEATEGLARITIAQDAKMNAMTFEMWSALPGLISRAAADPAIRAIVLTGAGEKA
CCEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCE
FCAGADISQFGARRSDPEAVAAYDHAVAAGMTALAGAEKPTVALIRGICFGGGFGLALAC
EECCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEE
DIRLARADARFRVPAARLGLGYGYEGVKLISRKLGPDATADILFSARILDAAEAERLGVV
EEEEECCCCCEECCHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
ARAWAAEAFETESAAYLGQIAANAPLTLVAAKRALVELARPEAERDLDAVAARVAACFAS
HHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ADYREGQAAFKEKRPPRFTGA
CCCCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA