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The map label for this gene is dapA [H]

Identifier: 158424102

GI number: 158424102

Start: 2815823

End: 2816743

Strand: Direct

Name: dapA [H]

Synonym: AZC_2478

Alternate gene names: 158424102

Gene position: 2815823-2816743 (Clockwise)

Preceding gene: 158424101

Following gene: 158424103

Centisome position: 52.44

GC content: 66.56

Gene sequence:

>921_bases
ATGCTGACCTCTTCCCAACTGCGCGGCATCTTTCCGGCCACTCCGACGCCGGTGAACGCGGACGACACCATCAACGTGGG
CGCCTCGAAGGCGCTGTTCTCCTGGCTACTGAAGCAGGGGATCGACGGACTCGTCCCGCTCGGCGGCACGGGCGAATACG
GCGCCCTGCCGCGGTCCGAGCGCATCAAGTTCGCGGGTCTCGCCGCGGAGGCCATGACGGGCAAGGGCCCGGTGATCGCC
GGCGTTCTGGACACCGGCTATCACGACGCGCTTCAGGCGGGCCGTGAGTTTGCGGCGGCGGGCGTGGACGGCCTGCTGGT
GCTCACGCCCTATTACACGAACCCGACCCAGGCCGGCATCCGCGATTATTTCCTGCGCTATGCCGATGCCTCGCCGGTGC
CGATCCTCATCTATGAAATCCCCTACCGTACCCGCATTGCCATCAATCCGGAGATCCTGCACGAGCTCTCCCGCCATGAG
CGCATCATCGGCATGAAGGCGTGCAACACCGACATGTACCACTTCCTGCGCACGGTCGCGGGCGTGGACGAGAGCTTCAC
CATGCTCAGCGGCGAGGACACGCTCTTCCCGCTGCACGTGGCGGCCGGCGCCAAGGGCGGCATCGTGGTGACGGCCAACC
TGGTGCCGAACGCCTGGCGCCAGATCTTCGACCTTGCCCTCGCCGGCAAGACGCAGGACGCGCTGGCTTTGCATCGCCGC
CTGATCCCGCTGATGAACATGGCCTTCGCCGAGACCAACCCCGGCCCCATGAAGGCGGTGATGGATCTCATCGGCGTGGA
TGCCCCGCGCATGCTGGCGCCGCTCGTCTCCGCCGCACCCGATCTCGCCGCGCGGCTGAGGAAGGAACTTCAACCGCTGT
TGCAGGAATTCGAATGCGTTCCGCACGCCCTCGCCTCCTGA

Upstream 100 bases:

>100_bases
TCTTCATCTTCATCGCGGTGCTGATCTTCGTTGCCGACCGGCTGCGCCGGCGCAGCCTCGCCAGCTGACCGCAAACCCCG
TCACAGACCCAGGGCTCTCC

Downstream 100 bases:

>100_bases
ACCCGAAGGCCGCGCGGCCGTATTGTGCATCTGCATTGCCATTGACGGCCGCGCGGCGAACCCGAAATTTAAAGGCATCA
TGCGCAAGCCCAGCCGGACC

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MLTSSQLRGIFPATPTPVNADDTINVGASKALFSWLLKQGIDGLVPLGGTGEYGALPRSERIKFAGLAAEAMTGKGPVIA
GVLDTGYHDALQAGREFAAAGVDGLLVLTPYYTNPTQAGIRDYFLRYADASPVPILIYEIPYRTRIAINPEILHELSRHE
RIIGMKACNTDMYHFLRTVAGVDESFTMLSGEDTLFPLHVAAGAKGGIVVTANLVPNAWRQIFDLALAGKTQDALALHRR
LIPLMNMAFAETNPGPMKAVMDLIGVDAPRMLAPLVSAAPDLAARLRKELQPLLQEFECVPHALAS

Sequences:

>Translated_306_residues
MLTSSQLRGIFPATPTPVNADDTINVGASKALFSWLLKQGIDGLVPLGGTGEYGALPRSERIKFAGLAAEAMTGKGPVIA
GVLDTGYHDALQAGREFAAAGVDGLLVLTPYYTNPTQAGIRDYFLRYADASPVPILIYEIPYRTRIAINPEILHELSRHE
RIIGMKACNTDMYHFLRTVAGVDESFTMLSGEDTLFPLHVAAGAKGGIVVTANLVPNAWRQIFDLALAGKTQDALALHRR
LIPLMNMAFAETNPGPMKAVMDLIGVDAPRMLAPLVSAAPDLAARLRKELQPLLQEFECVPHALAS
>Mature_306_residues
MLTSSQLRGIFPATPTPVNADDTINVGASKALFSWLLKQGIDGLVPLGGTGEYGALPRSERIKFAGLAAEAMTGKGPVIA
GVLDTGYHDALQAGREFAAAGVDGLLVLTPYYTNPTQAGIRDYFLRYADASPVPILIYEIPYRTRIAINPEILHELSRHE
RIIGMKACNTDMYHFLRTVAGVDESFTMLSGEDTLFPLHVAAGAKGGIVVTANLVPNAWRQIFDLALAGKTQDALALHRR
LIPLMNMAFAETNPGPMKAVMDLIGVDAPRMLAPLVSAAPDLAARLRKELQPLLQEFECVPHALAS

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=286, Percent_Identity=27.2727272727273, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI13540533, Length=307, Percent_Identity=25.7328990228013, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1788823, Length=264, Percent_Identity=29.5454545454545, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786463, Length=256, Percent_Identity=28.125, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI87082415, Length=244, Percent_Identity=26.6393442622951, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789620, Length=297, Percent_Identity=24.2424242424242, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32900; Mature: 32900

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTSSQLRGIFPATPTPVNADDTINVGASKALFSWLLKQGIDGLVPLGGTGEYGALPRSE
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCC
RIKFAGLAAEAMTGKGPVIAGVLDTGYHDALQAGREFAAAGVDGLLVLTPYYTNPTQAGI
CEEEHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHH
RDYFLRYADASPVPILIYEIPYRTRIAINPEILHELSRHERIIGMKACNTDMYHFLRTVA
HHHHHHHCCCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHEEEHHHCCHHHHHHHHHHH
GVDESFTMLSGEDTLFPLHVAAGAKGGIVVTANLVPNAWRQIFDLALAGKTQDALALHRR
CCCCCEEEECCCCCEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHH
LIPLMNMAFAETNPGPMKAVMDLIGVDAPRMLAPLVSAAPDLAARLRKELQPLLQEFECV
HHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
PHALAS
HHHHCC
>Mature Secondary Structure
MLTSSQLRGIFPATPTPVNADDTINVGASKALFSWLLKQGIDGLVPLGGTGEYGALPRSE
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCC
RIKFAGLAAEAMTGKGPVIAGVLDTGYHDALQAGREFAAAGVDGLLVLTPYYTNPTQAGI
CEEEHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHH
RDYFLRYADASPVPILIYEIPYRTRIAINPEILHELSRHERIIGMKACNTDMYHFLRTVA
HHHHHHHCCCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHEEEHHHCCHHHHHHHHHHH
GVDESFTMLSGEDTLFPLHVAAGAKGGIVVTANLVPNAWRQIFDLALAGKTQDALALHRR
CCCCCEEEECCCCCEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHH
LIPLMNMAFAETNPGPMKAVMDLIGVDAPRMLAPLVSAAPDLAARLRKELQPLLQEFECV
HHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
PHALAS
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA