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The map label for this gene is 158424083

Identifier: 158424083

GI number: 158424083

Start: 2793861

End: 2794835

Strand: Reverse

Name: 158424083

Synonym: AZC_2459

Alternate gene names: NA

Gene position: 2794835-2793861 (Counterclockwise)

Preceding gene: 158424084

Following gene: 158424082

Centisome position: 52.05

GC content: 62.87

Gene sequence:

>975_bases
GTGTCGACGCTTCACGACAGCCTGATCGTCATTGACGGCCTGATCATTTCCGATTTCAGCCGCCCGGTTTTCGAGGACAT
GCGCAAGGGCGGCCTGACGGCCGCCAACTGCACCTGCTCGGTGTGGGAGAACTTCACCGAGACCATGCGCAACATCGCCA
AGTGGAAGGCGGATTTCCGCACACACGCGGATCTCATCACGCAGGTCTACACCACCGGGGACATCCTCCGCGCCAAGGCG
GAGAACAAGACGGGCATCATCCTCGGCTGGCAGAACACCAGTGCCATCGACGACCGCATCGAATATCTGCCGCTGTTCCA
CGAACTCGGCATCCGCATCATCCAGATGACCTACAACACCCAGAACTGGGTGGGCTCGGGCTGCTACGAGAGCCGCGACA
GCGGCCTCTCCGACTTCGGCCATGACGTGGTGGCGGAGATGAACCGCCTCGGCATCCTGTGCGATCTCTCGCATGTGGGA
CCGAAGACCTCCGAGGATGTCATCAAGGCGTCCAAGCAGCGCGTGGCCTATTCCCACTGCCTGCCGTCCGGCCTCAAGGA
GCACAAGCGCAACAAGAGCGACGAGCAGTTGCGCTTCATCGCCGAGAAGGGCGGCTTCGTCGGCGTGACCATGTTCCCGC
CCTTCCTCAAGAAAGGCCCGGCCGCGACGGTCGCCGATTATGTCGAGGCGATGGAATACGTCATCAACCTCGTGGGCGAG
GATATCGTCGGCGTCGGGACCGACTTCACGCAGGGCTATGGCCAGCCCTTCTTCGACTGGATCACCCACGACAAGGGTTT
CGGCCGCAAGCTCACCGACTTCGGCGCGGTCATCAATCCCGAGGGCTTCCGCGAGATCGGCGACTTCCCGAACCTCACCG
CCGCCATGGAGCAGCGCGGCTGGTCCACGGGTCGCATCGAGAAGGTGATGGGCGGCAACTGGCTGCAGCTCCTGAAGGAC
GTGTGGGGCCGCTGA

Upstream 100 bases:

>100_bases
CCGGTTCATGTCTCCTGGCAGCCGGAGGCGGCGGTTCTCGTGCCGCTCTGAGCTTCCGGTCTCCGCCCATTTTCCATTTT
TCAAGCGAAGGAAGAGTATC

Downstream 100 bases:

>100_bases
GGCCCCGCTCATCGCGCCGCAACAGAAGGAACCGTCCGTGGCCAAGCCTGAAATCGAACTCGACGTCGATCCGGAAACAG
GGCGCTGGTACGCCGACCAG

Product: renal dipeptidase

Products: NA

Alternate protein names: ORF X [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MSTLHDSLIVIDGLIISDFSRPVFEDMRKGGLTAANCTCSVWENFTETMRNIAKWKADFRTHADLITQVYTTGDILRAKA
ENKTGIILGWQNTSAIDDRIEYLPLFHELGIRIIQMTYNTQNWVGSGCYESRDSGLSDFGHDVVAEMNRLGILCDLSHVG
PKTSEDVIKASKQRVAYSHCLPSGLKEHKRNKSDEQLRFIAEKGGFVGVTMFPPFLKKGPAATVADYVEAMEYVINLVGE
DIVGVGTDFTQGYGQPFFDWITHDKGFGRKLTDFGAVINPEGFREIGDFPNLTAAMEQRGWSTGRIEKVMGGNWLQLLKD
VWGR

Sequences:

>Translated_324_residues
MSTLHDSLIVIDGLIISDFSRPVFEDMRKGGLTAANCTCSVWENFTETMRNIAKWKADFRTHADLITQVYTTGDILRAKA
ENKTGIILGWQNTSAIDDRIEYLPLFHELGIRIIQMTYNTQNWVGSGCYESRDSGLSDFGHDVVAEMNRLGILCDLSHVG
PKTSEDVIKASKQRVAYSHCLPSGLKEHKRNKSDEQLRFIAEKGGFVGVTMFPPFLKKGPAATVADYVEAMEYVINLVGE
DIVGVGTDFTQGYGQPFFDWITHDKGFGRKLTDFGAVINPEGFREIGDFPNLTAAMEQRGWSTGRIEKVMGGNWLQLLKD
VWGR
>Mature_323_residues
STLHDSLIVIDGLIISDFSRPVFEDMRKGGLTAANCTCSVWENFTETMRNIAKWKADFRTHADLITQVYTTGDILRAKAE
NKTGIILGWQNTSAIDDRIEYLPLFHELGIRIIQMTYNTQNWVGSGCYESRDSGLSDFGHDVVAEMNRLGILCDLSHVGP
KTSEDVIKASKQRVAYSHCLPSGLKEHKRNKSDEQLRFIAEKGGFVGVTMFPPFLKKGPAATVADYVEAMEYVINLVGED
IVGVGTDFTQGYGQPFFDWITHDKGFGRKLTDFGAVINPEGFREIGDFPNLTAAMEQRGWSTGRIEKVMGGNWLQLLKDV
WGR

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI11641269, Length=256, Percent_Identity=27.34375, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI189458885, Length=268, Percent_Identity=25, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI4758190, Length=268, Percent_Identity=25, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI193211608, Length=249, Percent_Identity=24.0963855421687, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI193211610, Length=249, Percent_Identity=24.0963855421687, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI281362638, Length=294, Percent_Identity=27.5510204081633, Blast_Score=111, Evalue=7e-25,
Organism=Drosophila melanogaster, GI281362636, Length=294, Percent_Identity=27.5510204081633, Blast_Score=111, Evalue=7e-25,
Organism=Drosophila melanogaster, GI221475880, Length=262, Percent_Identity=25.5725190839695, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI161083233, Length=262, Percent_Identity=26.7175572519084, Blast_Score=103, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 36246; Mature: 36114

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLHDSLIVIDGLIISDFSRPVFEDMRKGGLTAANCTCSVWENFTETMRNIAKWKADFR
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
THADLITQVYTTGDILRAKAENKTGIILGWQNTSAIDDRIEYLPLFHELGIRIIQMTYNT
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEEEECC
QNWVGSGCYESRDSGLSDFGHDVVAEMNRLGILCDLSHVGPKTSEDVIKASKQRVAYSHC
CCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCEEEEHHHCCCCCHHHHHHHHHHHHHHHHH
LPSGLKEHKRNKSDEQLRFIAEKGGFVGVTMFPPFLKKGPAATVADYVEAMEYVINLVGE
CHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHCC
DIVGVGTDFTQGYGQPFFDWITHDKGFGRKLTDFGAVINPEGFREIGDFPNLTAAMEQRG
HHHCCCCCHHHHCCCHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHCCCCCHHHHHHHCC
WSTGRIEKVMGGNWLQLLKDVWGR
CCCCCHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure 
STLHDSLIVIDGLIISDFSRPVFEDMRKGGLTAANCTCSVWENFTETMRNIAKWKADFR
CCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
THADLITQVYTTGDILRAKAENKTGIILGWQNTSAIDDRIEYLPLFHELGIRIIQMTYNT
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEEEECC
QNWVGSGCYESRDSGLSDFGHDVVAEMNRLGILCDLSHVGPKTSEDVIKASKQRVAYSHC
CCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCEEEEHHHCCCCCHHHHHHHHHHHHHHHHH
LPSGLKEHKRNKSDEQLRFIAEKGGFVGVTMFPPFLKKGPAATVADYVEAMEYVINLVGE
CHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHCC
DIVGVGTDFTQGYGQPFFDWITHDKGFGRKLTDFGAVINPEGFREIGDFPNLTAAMEQRG
HHHCCCCCHHHHCCCHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHCCCCCHHHHHHHCC
WSTGRIEKVMGGNWLQLLKDVWGR
CCCCCHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1313537 [H]