Click here to switch to the map view.

The map label for this gene is 158424070

Identifier: 158424070

GI number: 158424070

Start: 2781818

End: 2782615

Strand: Direct

Name: 158424070

Synonym: AZC_2446

Alternate gene names: NA

Gene position: 2781818-2782615 (Clockwise)

Preceding gene: 158424069

Following gene: 158424071

Centisome position: 51.81

GC content: 64.91

Gene sequence:

>798_bases
ATGGATCATCCCATGACCGCGACCGACACCACCGCCGCCTGCCCGGCGCACATGGACCCGAGCGAATGGGACGCCCGCGT
CACGCTCGCCGCCTGCTACCGCATGGTGGCCAAGCTCGGGCTGGATGATCTCATCTACAACCACATCTCCTGCCGCGTGC
CGGGGCATGAGGACCAGTTCCTCATCAATCCCTATGGCCTGCTGTTCAGCGAGATGACGGCCTCCAGCCTCGTCAAGATC
GACATCGAGGGCCGCAAGCTGCAGGAAACGCCCTATGAGGTGAACCTCGCCGCCTTCGTCATCCATGCGGCGCTCCACAA
GACAAGCCATGACGCGGTCTGCGTGCTGCACACCCATTCGGATGCCAGCGTCGCGGTGTCCGGGCAGGAGCAGGGCCTCC
TGCCGCTCAGCCAGTTCGCGATGCGCTTCTACAACCGGCAGGCCTTCCACGATTACGAGGGAGTCGCCATCGACCTCGAC
GAGCAGCAGCGTCTGGTGCGCGATCTCGGGCCCCACAAGGTCATGCTCATGCGCAACCACGGCATCCTCACCGTCGGCCG
CACGCCGGGGGAAGCCTTCATGCTGCTCTATTATTTCGAGCGTGCCGCCAAGATCCAGCTCGCCATGCAGGCCGCCTGCG
CCTCCGGTGTGAAGCTCGTCATGCCCCCGCATGAGGTCTGCGAGCATGCCGCCCGCCAGTTCTGGGAGCTTAAGGGCGAC
ATTCTCGTGCCCGGCGAGCGCGAATGGCCCGCGCTCATGCGCCAGCTCGACCGCGAAGATCCGTCCTACCGCCAATAA

Upstream 100 bases:

>100_bases
CGGACCCGGAATTCGTGCGCCTGAAGCGCATCCTGCTGGAAGCCATCGAGGAGGAGGCCATGAAGTCCTTCCTCGCCCCC
GGCGCTTCCGGCACCCACTG

Downstream 100 bases:

>100_bases
CAGCCAACACCTTCCGGAGACGAAGACGATGACTGAACGGGTTGAAAAGACGCGCCGCACAGGTCCGAGCCGCCGGCATG
TGATGGCCGGCCTCGCCGCG

Product: aldolase II superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MDHPMTATDTTAACPAHMDPSEWDARVTLAACYRMVAKLGLDDLIYNHISCRVPGHEDQFLINPYGLLFSEMTASSLVKI
DIEGRKLQETPYEVNLAAFVIHAALHKTSHDAVCVLHTHSDASVAVSGQEQGLLPLSQFAMRFYNRQAFHDYEGVAIDLD
EQQRLVRDLGPHKVMLMRNHGILTVGRTPGEAFMLLYYFERAAKIQLAMQAACASGVKLVMPPHEVCEHAARQFWELKGD
ILVPGEREWPALMRQLDREDPSYRQ

Sequences:

>Translated_265_residues
MDHPMTATDTTAACPAHMDPSEWDARVTLAACYRMVAKLGLDDLIYNHISCRVPGHEDQFLINPYGLLFSEMTASSLVKI
DIEGRKLQETPYEVNLAAFVIHAALHKTSHDAVCVLHTHSDASVAVSGQEQGLLPLSQFAMRFYNRQAFHDYEGVAIDLD
EQQRLVRDLGPHKVMLMRNHGILTVGRTPGEAFMLLYYFERAAKIQLAMQAACASGVKLVMPPHEVCEHAARQFWELKGD
ILVPGEREWPALMRQLDREDPSYRQ
>Mature_265_residues
MDHPMTATDTTAACPAHMDPSEWDARVTLAACYRMVAKLGLDDLIYNHISCRVPGHEDQFLINPYGLLFSEMTASSLVKI
DIEGRKLQETPYEVNLAAFVIHAALHKTSHDAVCVLHTHSDASVAVSGQEQGLLPLSQFAMRFYNRQAFHDYEGVAIDLD
EQQRLVRDLGPHKVMLMRNHGILTVGRTPGEAFMLLYYFERAAKIQLAMQAACASGVKLVMPPHEVCEHAARQFWELKGD
ILVPGEREWPALMRQLDREDPSYRQ

Specific function: Unknown

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family [H]

Homologues:

Organism=Homo sapiens, GI29826325, Length=248, Percent_Identity=38.7096774193548, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI29826323, Length=248, Percent_Identity=38.7096774193548, Blast_Score=158, Evalue=4e-39,
Organism=Homo sapiens, GI29826321, Length=242, Percent_Identity=38.8429752066116, Blast_Score=158, Evalue=6e-39,
Organism=Homo sapiens, GI29826319, Length=241, Percent_Identity=39.4190871369295, Blast_Score=157, Evalue=7e-39,
Organism=Homo sapiens, GI89276787, Length=243, Percent_Identity=32.0987654320988, Blast_Score=128, Evalue=5e-30,
Organism=Homo sapiens, GI297307160, Length=243, Percent_Identity=32.0987654320988, Blast_Score=128, Evalue=5e-30,
Organism=Homo sapiens, GI9257190, Length=243, Percent_Identity=32.0987654320988, Blast_Score=128, Evalue=5e-30,
Organism=Homo sapiens, GI297307158, Length=243, Percent_Identity=32.0987654320988, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI9257192, Length=243, Percent_Identity=32.0987654320988, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI9951927, Length=195, Percent_Identity=37.4358974358974, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI62912453, Length=195, Percent_Identity=37.4358974358974, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI9943848, Length=195, Percent_Identity=37.4358974358974, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI115533216, Length=254, Percent_Identity=37.4015748031496, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI115533218, Length=256, Percent_Identity=37.109375, Blast_Score=154, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI71989544, Length=240, Percent_Identity=33.75, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI71989550, Length=240, Percent_Identity=33.75, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI71989555, Length=240, Percent_Identity=33.75, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI71989560, Length=240, Percent_Identity=33.75, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI71989541, Length=240, Percent_Identity=33.75, Blast_Score=117, Evalue=7e-27,
Organism=Drosophila melanogaster, GI281363755, Length=187, Percent_Identity=36.3636363636364, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI281363751, Length=187, Percent_Identity=36.3636363636364, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24655690, Length=187, Percent_Identity=36.3636363636364, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24655685, Length=187, Percent_Identity=36.3636363636364, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI281363763, Length=187, Percent_Identity=36.3636363636364, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI281363757, Length=187, Percent_Identity=36.3636363636364, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI17136738, Length=187, Percent_Identity=36.3636363636364, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI281363761, Length=187, Percent_Identity=36.3636363636364, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI281363759, Length=187, Percent_Identity=36.3636363636364, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI281363753, Length=187, Percent_Identity=36.3636363636364, Blast_Score=114, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: NA

Molecular weight: Translated: 29857; Mature: 29857

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHPMTATDTTAACPAHMDPSEWDARVTLAACYRMVAKLGLDDLIYNHISCRVPGHEDQF
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHEEEECCCCCCCE
LINPYGLLFSEMTASSLVKIDIEGRKLQETPYEVNLAAFVIHAALHKTSHDAVCVLHTHS
EECHHHHHHHHHHHCCEEEEEECCCEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEECC
DASVAVSGQEQGLLPLSQFAMRFYNRQAFHDYEGVAIDLDEQQRLVRDLGPHKVMLMRNH
CCEEEECCCCCCCCHHHHHHHHHHCCHHCCCCCCEEEECHHHHHHHHHCCCCEEEEEECC
GILTVGRTPGEAFMLLYYFERAAKIQLAMQAACASGVKLVMPPHEVCEHAARQFWELKGD
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCC
ILVPGEREWPALMRQLDREDPSYRQ
EECCCCCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MDHPMTATDTTAACPAHMDPSEWDARVTLAACYRMVAKLGLDDLIYNHISCRVPGHEDQF
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHEEEECCCCCCCE
LINPYGLLFSEMTASSLVKIDIEGRKLQETPYEVNLAAFVIHAALHKTSHDAVCVLHTHS
EECHHHHHHHHHHHCCEEEEEECCCEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEECC
DASVAVSGQEQGLLPLSQFAMRFYNRQAFHDYEGVAIDLDEQQRLVRDLGPHKVMLMRNH
CCEEEECCCCCCCCHHHHHHHHHHCCHHCCCCCCEEEECHHHHHHHHHCCCCEEEEEECC
GILTVGRTPGEAFMLLYYFERAAKIQLAMQAACASGVKLVMPPHEVCEHAARQFWELKGD
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCC
ILVPGEREWPALMRQLDREDPSYRQ
EECCCCCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]