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The map label for this gene is cfa [H]

Identifier: 158424062

GI number: 158424062

Start: 2773575

End: 2774798

Strand: Direct

Name: cfa [H]

Synonym: AZC_2438

Alternate gene names: 158424062

Gene position: 2773575-2774798 (Clockwise)

Preceding gene: 158424061

Following gene: 158424069

Centisome position: 51.65

GC content: 65.93

Gene sequence:

>1224_bases
ATGTCGGTAGAAAGTGAACACCGCGGCGCCGTCGTGTCGCGTGAAGCCCCCGCGCGGGGCATCGGCCCCTTCATCCTGAA
GCGCCTGCTGTCGCGCCTGTCCCGTGGGCGGCTGACGGTGATTCTCCCCTCCGGCGGGCGGATCGAGAGCGCGATGCGCG
CGCCGGGGCCGGAAGCAACCCTCGTTCTCCACAACTGGCGCACCTTCCGCCGCTTCGCCGCGCGCGGGCAGGTGGGCTTT
GCCGAAGCCTATATGGCGGGGGAATGGAGCAGCTCCGATCCGGCGGCGCTCATCGAGCTTGCGGCCATCAATATCGAGCG
GCTGGAGGCGGCGCTCAGCGGCTTCTGGCCGGTGCGGCTCGCGCGTCGCCTCACCCACGCCCGGCGCGCCAACACAAAGA
AGGGCAGCCGGAAGAACATCTCCTTCCACTACGATCTCGGCAACGATTTCTACCGCCTCTGGCTCGATCCCTCGATGACC
TATTCAAGCGCCATCTTCGAGCCGCCGACGCTCTCCCTCGAGGAGGCACAGGACGCGAAGCTCGCCCGGATCGGTAGCTG
GCTCGATATCGGTGCCGCGGGCACCCGCATTCTTGAGATCGGCTGCGGCTGGGGCGCGCTCGCCTCCAAGCTCGCGCACA
TGGGTGCCCATGTGACCGGACTGACCCTCTCCAAGGAACAGCTTGCCTTCGCCCAGGAGCGGATCGCGCGCGAGGGCATG
GCCGAGCGCGTGGACCTGCGCCTTCAGGATTATCGCGATGTGGTGGGGCAGTTCGACCGCATCGTCTCCATCGAGATGCT
GGAGGCGGTGGGCGAGCAATACTGGCCGGTCTATTTCGGAGCCATCAAGAAGCATCTCGTGCCCGGTGGCGTCGCGGTCC
TGCAAGGCATCACCATCGACGAGCCGCGCTATGAGGGCTACCGCGCCAATCCGGACTTCATCCAGCACTATATCTTTCCC
GGTGGCATGCTGCCGACCAAGGAGATCATGGCCGCGCAGGCGAAGGCGGCGGGCCTCGTGCTGGAGAAGGTGGAGAGTTT
CGGCCTCAGCTATGCCATGACGCTCGCCGAATGGCGCCGCCGCTTCCTTGCCGCCTGGCCGGCCATCGAGAAGATGGGCT
TCGACACCACCTTTAAGCGCCTCTGGGAGTATTATCTCGCTTATTGCGAGGGGGGCTTCCGCGCCGGTGTGATCGACGTT
TCGCTCTATCGCCTGCGGGCCTGA

Upstream 100 bases:

>100_bases
TCAGATCTTTCTGAAGGGCATCGGGTTGAGGCACCGCCCCCCTCCGCCCGTCCACCCCGTCACGGTTGCGCGTTCCGACA
CATGAGGGTTCTGGCGGAAA

Downstream 100 bases:

>100_bases
GGGGGCATCGCCCCCTCTTCTCACTCCAGAAACTCGAACCCCATGGTGCGGGCGTGATAGTGCAGCCCGCCGTCCTGCAC
GATGAGGAACAGCGCCCTGC

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MSVESEHRGAVVSREAPARGIGPFILKRLLSRLSRGRLTVILPSGGRIESAMRAPGPEATLVLHNWRTFRRFAARGQVGF
AEAYMAGEWSSSDPAALIELAAINIERLEAALSGFWPVRLARRLTHARRANTKKGSRKNISFHYDLGNDFYRLWLDPSMT
YSSAIFEPPTLSLEEAQDAKLARIGSWLDIGAAGTRILEIGCGWGALASKLAHMGAHVTGLTLSKEQLAFAQERIAREGM
AERVDLRLQDYRDVVGQFDRIVSIEMLEAVGEQYWPVYFGAIKKHLVPGGVAVLQGITIDEPRYEGYRANPDFIQHYIFP
GGMLPTKEIMAAQAKAAGLVLEKVESFGLSYAMTLAEWRRRFLAAWPAIEKMGFDTTFKRLWEYYLAYCEGGFRAGVIDV
SLYRLRA

Sequences:

>Translated_407_residues
MSVESEHRGAVVSREAPARGIGPFILKRLLSRLSRGRLTVILPSGGRIESAMRAPGPEATLVLHNWRTFRRFAARGQVGF
AEAYMAGEWSSSDPAALIELAAINIERLEAALSGFWPVRLARRLTHARRANTKKGSRKNISFHYDLGNDFYRLWLDPSMT
YSSAIFEPPTLSLEEAQDAKLARIGSWLDIGAAGTRILEIGCGWGALASKLAHMGAHVTGLTLSKEQLAFAQERIAREGM
AERVDLRLQDYRDVVGQFDRIVSIEMLEAVGEQYWPVYFGAIKKHLVPGGVAVLQGITIDEPRYEGYRANPDFIQHYIFP
GGMLPTKEIMAAQAKAAGLVLEKVESFGLSYAMTLAEWRRRFLAAWPAIEKMGFDTTFKRLWEYYLAYCEGGFRAGVIDV
SLYRLRA
>Mature_406_residues
SVESEHRGAVVSREAPARGIGPFILKRLLSRLSRGRLTVILPSGGRIESAMRAPGPEATLVLHNWRTFRRFAARGQVGFA
EAYMAGEWSSSDPAALIELAAINIERLEAALSGFWPVRLARRLTHARRANTKKGSRKNISFHYDLGNDFYRLWLDPSMTY
SSAIFEPPTLSLEEAQDAKLARIGSWLDIGAAGTRILEIGCGWGALASKLAHMGAHVTGLTLSKEQLAFAQERIAREGMA
ERVDLRLQDYRDVVGQFDRIVSIEMLEAVGEQYWPVYFGAIKKHLVPGGVAVLQGITIDEPRYEGYRANPDFIQHYIFPG
GMLPTKEIMAAQAKAAGLVLEKVESFGLSYAMTLAEWRRRFLAAWPAIEKMGFDTTFKRLWEYYLAYCEGGFRAGVIDVS
LYRLRA

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=360, Percent_Identity=37.7777777777778, Blast_Score=196, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI133904226, Length=409, Percent_Identity=35.6968215158924, Blast_Score=229, Evalue=3e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 45448; Mature: 45317

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVESEHRGAVVSREAPARGIGPFILKRLLSRLSRGRLTVILPSGGRIESAMRAPGPEAT
CCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCCCEE
LVLHNWRTFRRFAARGQVGFAEAYMAGEWSSSDPAALIELAAINIERLEAALSGFWPVRL
EEEECHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
ARRLTHARRANTKKGSRKNISFHYDLGNDFYRLWLDPSMTYSSAIFEPPTLSLEEAQDAK
HHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEEECCCCCHHHHCCCCCCCCHHHHHCHH
LARIGSWLDIGAAGTRILEIGCGWGALASKLAHMGAHVTGLTLSKEQLAFAQERIAREGM
HHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHCH
AERVDLRLQDYRDVVGQFDRIVSIEMLEAVGEQYWPVYFGAIKKHLVPGGVAVLQGITID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCHHHHHHHHHHCCCCCHHHHCCCCCC
EPRYEGYRANPDFIQHYIFPGGMLPTKEIMAAQAKAAGLVLEKVESFGLSYAMTLAEWRR
CCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
RFLAAWPAIEKMGFDTTFKRLWEYYLAYCEGGFRAGVIDVSLYRLRA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEECEEEEEEEEECC
>Mature Secondary Structure 
SVESEHRGAVVSREAPARGIGPFILKRLLSRLSRGRLTVILPSGGRIESAMRAPGPEAT
CCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCCCEE
LVLHNWRTFRRFAARGQVGFAEAYMAGEWSSSDPAALIELAAINIERLEAALSGFWPVRL
EEEECHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
ARRLTHARRANTKKGSRKNISFHYDLGNDFYRLWLDPSMTYSSAIFEPPTLSLEEAQDAK
HHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEEECCCCCHHHHCCCCCCCCHHHHHCHH
LARIGSWLDIGAAGTRILEIGCGWGALASKLAHMGAHVTGLTLSKEQLAFAQERIAREGM
HHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHCH
AERVDLRLQDYRDVVGQFDRIVSIEMLEAVGEQYWPVYFGAIKKHLVPGGVAVLQGITID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCHHHHHHHHHHCCCCCHHHHCCCCCC
EPRYEGYRANPDFIQHYIFPGGMLPTKEIMAAQAKAAGLVLEKVESFGLSYAMTLAEWRR
CCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
RFLAAWPAIEKMGFDTTFKRLWEYYLAYCEGGFRAGVIDVSLYRLRA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEECEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]