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The map label for this gene is mdtA [H]

Identifier: 158424053

GI number: 158424053

Start: 2760981

End: 2762306

Strand: Direct

Name: mdtA [H]

Synonym: AZC_2429

Alternate gene names: 158424053

Gene position: 2760981-2762306 (Clockwise)

Preceding gene: 158424052

Following gene: 158424054

Centisome position: 51.42

GC content: 69.0

Gene sequence:

>1326_bases
ATGAACGAGCCCTTCCGCGATCCCAAGGGCGAGCCCGTCCAGCTTGACCTGCCCGAGGTTCCCGCGCGCAAGAAGCGCCG
GTTTCCCTGGTCGCTGCTCATCTGCGCGGCTCTGGTGGCTCTGGTCGGCGCCGGCTGGCTGATCCGCCCGCAGCAGCAGG
CGGGACCGGGCATGCGACGCGCCTTCAACGGTCCCGTGCCGGTCGCCACCGCGACGGTGGAGAAAGGTTCGCTCCCGGTC
ACGCTCACCGCGCTGGGCACCGTGACGCCGCTCACCACGGTAACGGTGCGCAGCCAGATTTCGGGCCGACTGACCAAGAT
CAGCTTTCAGGAAGGCCAGGATGTGAAGGCTGGTGATCCGCTGGCCGAGGTGGACCCGCGCCCCTATGAGGCGGCGCTGA
AGCAGGCGCAGGGCCAGCTCGCCCGCGATCAGGCCCAGCTGCGCAATGCGCAGCTCGATTTGACCCGCTACCAGACGCTG
GTGGCCAAATCCGCCGCGTCGCAGCAGTCGGTGGATACGCAGGAAGCCCTCGTCGCCCAGTATCAGGGCACGGTCCAGAT
GGACCAGGCTCAGGTGCGCACGGCCGAACTCAATCTCGAATACTGCCACATCGTCGCGCCCGTCTCCGGCCGCCTCGGCA
TCCGGCAGGTGGACGTCGGCAATTACGTGCAGGCGGGCGACAGCACCGGCATTGTGGTCATCACGCAGTTGAAGCCCATC
ACGGTGGTCTTCTCCCTGCCCGAAGACGTGGTGCCGCAGGTGGCCCGGCGCCTCGAGGCCAAGGCCGACCTGCCGGTCAC
CGTCTATGACCGCAACCGGCGCGCCAAGATCGCCACCGGCCAGCTCATCACCATCGACAACCAGGTGGACACCACCACGG
GCACGGTGAAGCTGAAGGCGCAGTTTCCGAACGACGACGGCAGCCTCTTCCCGAACCAGTTCGTGAATGTGGACCTTCTG
GTGAACACCATGGACGGCGCGGTCATCGTGCCCTCCGCCGCCGTCCAGCGCGGCGCGCCGGGGCCTTATGTCTATGTGGT
CGGCGCCGATCAGACGGTGAGCGTGCACAAGGTGAAGCTCGGCCCCTCGGCCGGCGACAAAATTGCCGTCCTTGAAGGGC
TCAATCCTGGCGACAAGGTGGTGGTCGACGGCGCCGACAAGCTGCGTGAAGGCGCGCAGGTGACCGAGCCGGACGCCGGC
CAGACGCCGGGCCAGCCCGGACGCCGGCCCGGAGGCCCCAACGCCGCGGCCGGTCAGGGCCCCTCCGGCGCACCGGGCGC
GCCCGGCAACGGCCAGCCGCGCCGGTCGCAGGCACCGACGCCGTGA

Upstream 100 bases:

>100_bases
TGGTGAAAGCGGCCATCGCAATGTCACCGGAAGGCCGCGAACGTCTCGCACGCTGGATTCCCTCAGGCGAAACCGGCCCC
GAACAGAAGAAGCGACCCAA

Downstream 100 bases:

>100_bases
ACCCGTCCCGTCCCTTCATCGAGCGCCCCGTCGCCACATCGCTGCTTATGGCGGCGGTGCTGCTGGTGGGCGCGCTCGCC
TTCCGCTTCCTGCCGCTCTC

Product: hemolysin D

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MNEPFRDPKGEPVQLDLPEVPARKKRRFPWSLLICAALVALVGAGWLIRPQQQAGPGMRRAFNGPVPVATATVEKGSLPV
TLTALGTVTPLTTVTVRSQISGRLTKISFQEGQDVKAGDPLAEVDPRPYEAALKQAQGQLARDQAQLRNAQLDLTRYQTL
VAKSAASQQSVDTQEALVAQYQGTVQMDQAQVRTAELNLEYCHIVAPVSGRLGIRQVDVGNYVQAGDSTGIVVITQLKPI
TVVFSLPEDVVPQVARRLEAKADLPVTVYDRNRRAKIATGQLITIDNQVDTTTGTVKLKAQFPNDDGSLFPNQFVNVDLL
VNTMDGAVIVPSAAVQRGAPGPYVYVVGADQTVSVHKVKLGPSAGDKIAVLEGLNPGDKVVVDGADKLREGAQVTEPDAG
QTPGQPGRRPGGPNAAAGQGPSGAPGAPGNGQPRRSQAPTP

Sequences:

>Translated_441_residues
MNEPFRDPKGEPVQLDLPEVPARKKRRFPWSLLICAALVALVGAGWLIRPQQQAGPGMRRAFNGPVPVATATVEKGSLPV
TLTALGTVTPLTTVTVRSQISGRLTKISFQEGQDVKAGDPLAEVDPRPYEAALKQAQGQLARDQAQLRNAQLDLTRYQTL
VAKSAASQQSVDTQEALVAQYQGTVQMDQAQVRTAELNLEYCHIVAPVSGRLGIRQVDVGNYVQAGDSTGIVVITQLKPI
TVVFSLPEDVVPQVARRLEAKADLPVTVYDRNRRAKIATGQLITIDNQVDTTTGTVKLKAQFPNDDGSLFPNQFVNVDLL
VNTMDGAVIVPSAAVQRGAPGPYVYVVGADQTVSVHKVKLGPSAGDKIAVLEGLNPGDKVVVDGADKLREGAQVTEPDAG
QTPGQPGRRPGGPNAAAGQGPSGAPGAPGNGQPRRSQAPTP
>Mature_441_residues
MNEPFRDPKGEPVQLDLPEVPARKKRRFPWSLLICAALVALVGAGWLIRPQQQAGPGMRRAFNGPVPVATATVEKGSLPV
TLTALGTVTPLTTVTVRSQISGRLTKISFQEGQDVKAGDPLAEVDPRPYEAALKQAQGQLARDQAQLRNAQLDLTRYQTL
VAKSAASQQSVDTQEALVAQYQGTVQMDQAQVRTAELNLEYCHIVAPVSGRLGIRQVDVGNYVQAGDSTGIVVITQLKPI
TVVFSLPEDVVPQVARRLEAKADLPVTVYDRNRRAKIATGQLITIDNQVDTTTGTVKLKAQFPNDDGSLFPNQFVNVDLL
VNTMDGAVIVPSAAVQRGAPGPYVYVVGADQTVSVHKVKLGPSAGDKIAVLEGLNPGDKVVVDGADKLREGAQVTEPDAG
QTPGQPGRRPGGPNAAAGQGPSGAPGAPGNGQPRRSQAPTP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=356, Percent_Identity=48.314606741573, Blast_Score=333, Evalue=2e-92,
Organism=Escherichia coli, GI1786668, Length=340, Percent_Identity=36.1764705882353, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1789929, Length=333, Percent_Identity=29.4294294294294, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1789665, Length=381, Percent_Identity=31.2335958005249, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI87081796, Length=384, Percent_Identity=25, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87081951, Length=159, Percent_Identity=31.4465408805031, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 46595; Mature: 46595

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEPFRDPKGEPVQLDLPEVPARKKRRFPWSLLICAALVALVGAGWLIRPQQQAGPGMRR
CCCCCCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHCCCCEECCHHHCCCCHHH
AFNGPVPVATATVEKGSLPVTLTALGTVTPLTTVTVRSQISGRLTKISFQEGQDVKAGDP
HCCCCCCEEEEEEECCCCCEEEEECCCCCCEEEEEEHHHHCCCEEEEEECCCCCCCCCCC
LAEVDPRPYEAALKQAQGQLARDQAQLRNAQLDLTRYQTLVAKSAASQQSVDTQEALVAQ
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHH
YQGTVQMDQAQVRTAELNLEYCHIVAPVSGRLGIRQVDVGNYVQAGDSTGIVVITQLKPI
HCCCEEECHHHEEEEEECEEEEEEEECCCCCCCEEEECCCCEEECCCCCCEEEEEECCEE
TVVFSLPEDVVPQVARRLEAKADLPVTVYDRNRRAKIATGQLITIDNQVDTTTGTVKLKA
EEEEECCHHHHHHHHHHHHHCCCCCEEEECCCCEEEEECCEEEEECCCCCCCCEEEEEEE
QFPNDDGSLFPNQFVNVDLLVNTMDGAVIVPSAAVQRGAPGPYVYVVGADQTVSVHKVKL
ECCCCCCCCCCCCEEEEEEEEEECCCEEECCHHHHHCCCCCCEEEEEECCCEEEEEEEEE
GPSAGDKIAVLEGLNPGDKVVVDGADKLREGAQVTEPDAGQTPGQPGRRPGGPNAAAGQG
CCCCCCEEEEEECCCCCCEEEECCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PSGAPGAPGNGQPRRSQAPTP
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNEPFRDPKGEPVQLDLPEVPARKKRRFPWSLLICAALVALVGAGWLIRPQQQAGPGMRR
CCCCCCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHCCCCEECCHHHCCCCHHH
AFNGPVPVATATVEKGSLPVTLTALGTVTPLTTVTVRSQISGRLTKISFQEGQDVKAGDP
HCCCCCCEEEEEEECCCCCEEEEECCCCCCEEEEEEHHHHCCCEEEEEECCCCCCCCCCC
LAEVDPRPYEAALKQAQGQLARDQAQLRNAQLDLTRYQTLVAKSAASQQSVDTQEALVAQ
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHH
YQGTVQMDQAQVRTAELNLEYCHIVAPVSGRLGIRQVDVGNYVQAGDSTGIVVITQLKPI
HCCCEEECHHHEEEEEECEEEEEEEECCCCCCCEEEECCCCEEECCCCCCEEEEEECCEE
TVVFSLPEDVVPQVARRLEAKADLPVTVYDRNRRAKIATGQLITIDNQVDTTTGTVKLKA
EEEEECCHHHHHHHHHHHHHCCCCCEEEECCCCEEEEECCEEEEECCCCCCCCEEEEEEE
QFPNDDGSLFPNQFVNVDLLVNTMDGAVIVPSAAVQRGAPGPYVYVVGADQTVSVHKVKL
ECCCCCCCCCCCCEEEEEEEEEECCCEEECCHHHHHCCCCCCEEEEEECCCEEEEEEEEE
GPSAGDKIAVLEGLNPGDKVVVDGADKLREGAQVTEPDAGQTPGQPGRRPGGPNAAAGQG
CCCCCCEEEEEECCCCCCEEEECCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PSGAPGAPGNGQPRRSQAPTP
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA