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The map label for this gene is hlyD [H]

Identifier: 158424050

GI number: 158424050

Start: 2758031

End: 2759206

Strand: Reverse

Name: hlyD [H]

Synonym: AZC_2426

Alternate gene names: 158424050

Gene position: 2759206-2758031 (Counterclockwise)

Preceding gene: 158424056

Following gene: 158424049

Centisome position: 51.38

GC content: 67.94

Gene sequence:

>1176_bases
ATGCGGCGGTGGATGTGGGCGGTGTTGGCGTTGGCGGCCGCAGGCGGGGCGGCGGCCTGGTGGCATGGAGTGCCGGGCAT
GTCCCCGGCGGTCGCCGCAAAGCCGATCCCCGCCGCCATTCCCGTGGTGGTCGCCGCGGCCGTGCCCAAGGACGTGCCGG
TCTATGCCACCGGCATCGGCGCCGCCCAGGCCTACAATTCGGTCACCGTGAAGGTGCGCGTGGACGGCGAACTGCAGAAG
GTGCTGTTCAAGGAGGGGCAGGATGTAAAGGCGGGCGAGGTGCTCGCCGAGATCGATCCGCGCACCTATCAGGCTGCGCT
TGCACAGGCGAAGGCCACGAAGGCCAAGGACGAGGCCCAGCTCGCCAATGCGAAGCTCGACCTCGACCGCTATGCCTCGC
TGGTGGAAAAGAACGCCACCTCCCGCCAGACGCTCGACACGCAGAAGGCGCTGGTCGCGCAATATGAGGCGGCCGTACAG
GGCGATCAGGCGGCCATCGACAATGCCACCGTCCAGCTCGGCTACACCACCATCCGCGCGCCCATCGATGGGCGGACGGG
CGTGCGGCAGGTGGATCAGGGCAACATCGTCCATGCCACAGACACCACCGGGCTCGTGGTCATCAGCCAGCTCAAGCCCA
TGTCGGTGATCTTCGCGCTGCCGCAGGAGCGTCTCGACGAGGTGGCGGCGGCCATGGCGCGCGGTCCGGTAGAGGTGATC
GCCTACAAGCGCGACGGCGTGACCGAGGTGGGCGAGGGCAAGGTCGAGCTCATCGACAACACCATCAATGCCGACACCGG
CACGCTGCGCCTCAAGGCCACCTTCCCCAATGATAATCTGACCCTGTGGCCCGGTGCCTTCGTGAACGTGAAGGTGCTGG
TGAACACGCTGAAGGACGAGATCACCATCCCGTCCCGCGCCGTCCAGCGCGGCCCGGCCGGGCCTTACGTGTTCGTCATC
GGCGCGGACAATGTGGCCCAGAAGCGCGATATCGCCGTCGTCTCGATGGCGGGGGAGACCGCCGTCATCAAGAGCGGGCT
CAAGCCCGGCGAGCAGGTGGTGATCGACGGCCAGTCCCGCCTCACCCCCGGTGCCAAGGTGGCGGTGCGCTCCGGCAAGA
CGGACGGCGGCGCCGTTCCTGCCGCCAGCATCGAGACGGGTGAGAAGGGCGCATGA

Upstream 100 bases:

>100_bases
CGCTACGTCATGCGGTCACGGGTGCGTGATGGCGGACATTTCCGCGCAGGGTTGCGCACGCGCGGGGGTTCAAACCCGTT
GAACCTATGAGGGCCTTACG

Downstream 100 bases:

>100_bases
GCATCTCCACCCCCTTCATCCGGCGTCCCATCGCCACCACGCTGCTCATGGTGGCGCTGGTTCTGGTGGGCGTCGTCGCC
TATCCGCTGTTGCCCGTGGC

Product: secretion protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MRRWMWAVLALAAAGGAAAWWHGVPGMSPAVAAKPIPAAIPVVVAAAVPKDVPVYATGIGAAQAYNSVTVKVRVDGELQK
VLFKEGQDVKAGEVLAEIDPRTYQAALAQAKATKAKDEAQLANAKLDLDRYASLVEKNATSRQTLDTQKALVAQYEAAVQ
GDQAAIDNATVQLGYTTIRAPIDGRTGVRQVDQGNIVHATDTTGLVVISQLKPMSVIFALPQERLDEVAAAMARGPVEVI
AYKRDGVTEVGEGKVELIDNTINADTGTLRLKATFPNDNLTLWPGAFVNVKVLVNTLKDEITIPSRAVQRGPAGPYVFVI
GADNVAQKRDIAVVSMAGETAVIKSGLKPGEQVVIDGQSRLTPGAKVAVRSGKTDGGAVPAASIETGEKGA

Sequences:

>Translated_391_residues
MRRWMWAVLALAAAGGAAAWWHGVPGMSPAVAAKPIPAAIPVVVAAAVPKDVPVYATGIGAAQAYNSVTVKVRVDGELQK
VLFKEGQDVKAGEVLAEIDPRTYQAALAQAKATKAKDEAQLANAKLDLDRYASLVEKNATSRQTLDTQKALVAQYEAAVQ
GDQAAIDNATVQLGYTTIRAPIDGRTGVRQVDQGNIVHATDTTGLVVISQLKPMSVIFALPQERLDEVAAAMARGPVEVI
AYKRDGVTEVGEGKVELIDNTINADTGTLRLKATFPNDNLTLWPGAFVNVKVLVNTLKDEITIPSRAVQRGPAGPYVFVI
GADNVAQKRDIAVVSMAGETAVIKSGLKPGEQVVIDGQSRLTPGAKVAVRSGKTDGGAVPAASIETGEKGA
>Mature_391_residues
MRRWMWAVLALAAAGGAAAWWHGVPGMSPAVAAKPIPAAIPVVVAAAVPKDVPVYATGIGAAQAYNSVTVKVRVDGELQK
VLFKEGQDVKAGEVLAEIDPRTYQAALAQAKATKAKDEAQLANAKLDLDRYASLVEKNATSRQTLDTQKALVAQYEAAVQ
GDQAAIDNATVQLGYTTIRAPIDGRTGVRQVDQGNIVHATDTTGLVVISQLKPMSVIFALPQERLDEVAAAMARGPVEVI
AYKRDGVTEVGEGKVELIDNTINADTGTLRLKATFPNDNLTLWPGAFVNVKVLVNTLKDEITIPSRAVQRGPAGPYVFVI
GADNVAQKRDIAVVSMAGETAVIKSGLKPGEQVVIDGQSRLTPGAKVAVRSGKTDGGAVPAASIETGEKGA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=355, Percent_Identity=43.3802816901408, Blast_Score=278, Evalue=6e-76,
Organism=Escherichia coli, GI1786668, Length=317, Percent_Identity=34.7003154574132, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789665, Length=316, Percent_Identity=33.2278481012658, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1789929, Length=326, Percent_Identity=31.2883435582822, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI87081796, Length=392, Percent_Identity=24.4897959183673, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40911; Mature: 40911

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRWMWAVLALAAAGGAAAWWHGVPGMSPAVAAKPIPAAIPVVVAAAVPKDVPVYATGIG
CCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCC
AAQAYNSVTVKVRVDGELQKVLFKEGQDVKAGEVLAEIDPRTYQAALAQAKATKAKDEAQ
HHHCCCEEEEEEEECCHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCHHHHH
LANAKLDLDRYASLVEKNATSRQTLDTQKALVAQYEAAVQGDQAAIDNATVQLGYTTIRA
HHHCEECHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEC
PIDGRTGVRQVDQGNIVHATDTTGLVVISQLKPMSVIFALPQERLDEVAAAMARGPVEVI
CCCCCCCCCCCCCCCEEEEECCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHCCCEEEE
AYKRDGVTEVGEGKVELIDNTINADTGTLRLKATFPNDNLTLWPGAFVNVKVLVNTLKDE
EECCCCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCEEECCCCEEEHHHHHHHHHHH
ITIPSRAVQRGPAGPYVFVIGADNVAQKRDIAVVSMAGETAVIKSGLKPGEQVVIDGQSR
CCCCHHHHHCCCCCCEEEEEECCCCCCCCCEEEEEECCCHHHHHCCCCCCCEEEECCCCC
LTPGAKVAVRSGKTDGGAVPAASIETGEKGA
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRRWMWAVLALAAAGGAAAWWHGVPGMSPAVAAKPIPAAIPVVVAAAVPKDVPVYATGIG
CCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCC
AAQAYNSVTVKVRVDGELQKVLFKEGQDVKAGEVLAEIDPRTYQAALAQAKATKAKDEAQ
HHHCCCEEEEEEEECCHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCHHHHH
LANAKLDLDRYASLVEKNATSRQTLDTQKALVAQYEAAVQGDQAAIDNATVQLGYTTIRA
HHHCEECHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEC
PIDGRTGVRQVDQGNIVHATDTTGLVVISQLKPMSVIFALPQERLDEVAAAMARGPVEVI
CCCCCCCCCCCCCCCEEEEECCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHCCCEEEE
AYKRDGVTEVGEGKVELIDNTINADTGTLRLKATFPNDNLTLWPGAFVNVKVLVNTLKDE
EECCCCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCEEECCCCEEEHHHHHHHHHHH
ITIPSRAVQRGPAGPYVFVIGADNVAQKRDIAVVSMAGETAVIKSGLKPGEQVVIDGQSR
CCCCHHHHHCCCCCCEEEEEECCCCCCCCCEEEEEECCCHHHHHCCCCCCCEEEECCCCC
LTPGAKVAVRSGKTDGGAVPAASIETGEKGA
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA