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The map label for this gene is fabZ [H]

Identifier: 158424028

GI number: 158424028

Start: 2731197

End: 2731670

Strand: Direct

Name: fabZ [H]

Synonym: AZC_2404

Alternate gene names: 158424028

Gene position: 2731197-2731670 (Clockwise)

Preceding gene: 158424027

Following gene: 158424029

Centisome position: 50.86

GC content: 65.4

Gene sequence:

>474_bases
ATGCGCCCTGAAGTTTTCAAGATGGTGGACCGCGTGGTCGCCATCGATCCCGGCCTTGAGACCATCCACTGCGAAGGTCT
GGTCCCGCACGAGAGCTCCATCTTCGAGGGGCACTTTCCCGGCCACCCGATCATGCCGGGGGTACTGCTGATCGAGGCCA
TGGCCCAGACCACGGGCTGGCTGGTGCTCGCCCGCAACCGCTTCGACAAGATGCCGTTCCTCGCGACGGTGAAGGAAGCC
AAGCTGCGCACCTTCGTGGTGCCCGGCCAGATGCTCGACCTCCACTCGCGCATCCTACACGAGGGCTCCGGCTTCGTGGT
GGCGCAGACCAAGGCGCTCATCGAAGGCAAGCCGGTGTGCAATGCGGAGCTGGTGTTCCGCGTCCTGCCCTGGCCGGAGG
GCCGCATGAAGGACGTGGTGCTGAAGGTGGCCGAGCGCGTGGAATTCCCGCTGGCGGACTTCGCCGATGCATGA

Upstream 100 bases:

>100_bases
CACCCGCCCGCCGGACCATTCAAGCCTGCGCGGCGCTTGAGCGAAACCCACGCGGCAACGGCCCTCGCCGCTGCCGTTGG
CATGACGTCGGACGGAGCGA

Downstream 100 bases:

>100_bases
CGACAGGAAGCCGGGCCAGCGCGACGTCTGGATCACCGGCATCGGCCTTGTCACCTCGCTTGGCGAGGGACTGGACGCCC
ACTGGACAGCGCTGGCTGAA

Product: 3-hydroxymyristoyl-acyl carrier protein dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MRPEVFKMVDRVVAIDPGLETIHCEGLVPHESSIFEGHFPGHPIMPGVLLIEAMAQTTGWLVLARNRFDKMPFLATVKEA
KLRTFVVPGQMLDLHSRILHEGSGFVVAQTKALIEGKPVCNAELVFRVLPWPEGRMKDVVLKVAERVEFPLADFADA

Sequences:

>Translated_157_residues
MRPEVFKMVDRVVAIDPGLETIHCEGLVPHESSIFEGHFPGHPIMPGVLLIEAMAQTTGWLVLARNRFDKMPFLATVKEA
KLRTFVVPGQMLDLHSRILHEGSGFVVAQTKALIEGKPVCNAELVFRVLPWPEGRMKDVVLKVAERVEFPLADFADA
>Mature_157_residues
MRPEVFKMVDRVVAIDPGLETIHCEGLVPHESSIFEGHFPGHPIMPGVLLIEAMAQTTGWLVLARNRFDKMPFLATVKEA
KLRTFVVPGQMLDLHSRILHEGSGFVVAQTKALIEGKPVCNAELVFRVLPWPEGRMKDVVLKVAERVEFPLADFADA

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=123, Percent_Identity=34.1463414634146, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 17496; Mature: 17496

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPEVFKMVDRVVAIDPGLETIHCEGLVPHESSIFEGHFPGHPIMPGVLLIEAMAQTTGW
CCCHHHHHHHHHHEECCCCCEEEECCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHCCCE
LVLARNRFDKMPFLATVKEAKLRTFVVPGQMLDLHSRILHEGSGFVVAQTKALIEGKPVC
EEEECCCCCCCCHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCEEEEECHHHHCCCCCC
NAELVFRVLPWPEGRMKDVVLKVAERVEFPLADFADA
CCEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHCCCC
>Mature Secondary Structure
MRPEVFKMVDRVVAIDPGLETIHCEGLVPHESSIFEGHFPGHPIMPGVLLIEAMAQTTGW
CCCHHHHHHHHHHEECCCCCEEEECCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHCCCE
LVLARNRFDKMPFLATVKEAKLRTFVVPGQMLDLHSRILHEGSGFVVAQTKALIEGKPVC
EEEECCCCCCCCHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCEEEEECHHHHCCCCCC
NAELVFRVLPWPEGRMKDVVLKVAERVEFPLADFADA
CCEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12566566 [H]