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The map label for this gene is aidB [H]

Identifier: 158424026

GI number: 158424026

Start: 2728895

End: 2730619

Strand: Direct

Name: aidB [H]

Synonym: AZC_2402

Alternate gene names: 158424026

Gene position: 2728895-2730619 (Clockwise)

Preceding gene: 158424024

Following gene: 158424027

Centisome position: 50.82

GC content: 71.88

Gene sequence:

>1725_bases
GTGAGGCGCGTGTCGGGCGCACTCTGGAGCCAGTCGCGGCCCGCAAAGAGGCCGCCCAGCCCCGGGAGGGTGCCCATGCC
AGTTTCCTTGCGCGAGGCCACGCGTCCGCCCGTGGCCGGACTGGAGGCGGAGGGTTTCAACCAGCCGCCGCCCTTCACGG
ATGTGGACCTTCTCGCCTGTGACGCCGCTCTGCGCGATGCGCTCGGGGCGCATGGTCCGGTGCCCGCCCATCTGCGCTCC
GCGGGCGCCGAGTGGGGCAGCCGGGAGCGCATGTGCCTCGGCCGGCAGGCCAACGAAAACCCGCCCCGCCTCCACTCCCA
TGATGCGCGGGGGCAGCGGCTCGATACGGTGGAATTCCATCCCGCCTACCACGCCTTGATGGCGGCGAGCAGCGCCGGCG
GCTTGCACTGCGCCACCTGGCAGGGGGAGCGGCACCTCCACCGGGCGGCCCGGCTTTATCTCACGGCGCAGGTGGAGGCG
GGGCACATCTGCCCGCTTACCATGACCCACGCCGCCCCCGCCGCCCTCGCCGCAGCCCCGGAGCTTCAGGCCGAATGGCT
GGGGCGCCTCACCTCCCGCCTCTATGACGGCCGCTTCCTGCCCTTCTGGGAAAAGACCGCCGTCACCCTCGGCATGGGGA
TGACCGAGAAGCAGGGCGGCACGGACGTGCGCGCCAACGTCACCCGCGCGGACCGCACCGGTGGCAGCGAATATGAGATC
AGCGGGCACAAATGGTTCTTTTCCGCGCCCATGTGCGATGCCTTCCTCGTGCTCGCCCAGGCGCCGGAAGGGCTGACCAC
CTTCCTCATGCCCCGCTTCCGGCCTGATGGCAGCGTGAACGGCCTCCGGCTCCAGCGGCTCAAGGACAAGCTCGGCAACC
GCTCCAATGCCTCCTCCGAGGTAGAGTTCGACCGTGCCTTCGCCTGGCGCGTCGGCGCCGAGGGGCGAGGCGTCGCCACC
ATCCTTGAGATGGTGCAGCTGACCCGCCTCGACTGCGCAGTCTCCTCCGCTGGCCTGATGCGGCGGGCACTGTCCGAGGC
GCTTCACAATGCCCGGCACCGCAGCGTGTTTGGCCGGCGGCTGGTGGTGCAGCCGGCCATGCGTCTTGTGCTCGCCGACC
TCGCGCTGGAGGCGGAAGCGGCGACGGCGCTCGCGATGCGCCTTGCCGCCAGCTTCGACGCGGCCGCCGGATCGCCGCAG
GAGGCCGCCCGCGCCCGGCTGCTGACGCCGGCGGTGAAGTTCGCCGTCTGCAAGGCGGCCCCCGACTTCATCTATGAAGC
CATGGAGGCGGTGGGCGGCAATGGCTATGTGGAAGACAGTCCGCTGCCGCGCCTGTTCCGGGAGGCGCCGGTGAATGCCA
TATGGGAAGGCACCGGAACGGTGGTGGCGCTCGATCTGCTGCGCGCCGCCGGCCGCGATCCGCAGGCCATGGCGCTGCTG
CTCGACGACCTCGGTCGCGAGGCCGGCGGCCTGCCGGGCGTGACGGCGACCATCCGGCAGGTATCCGGCCTGCTGCGCGA
CCCGGAGCCCGAACGCCACGCACGCCTTGCGGCCCAGCGCATTGCGATTCTCGCCGCCACCGCCGCCCTCGCCCGACAGG
CTCCGGCTGCGGTAGCCGAGGCCTTCGCGCGCACCCGCCTTGCGGCCGGCGCGGGTCTCATCGGCACCAACGAGGTCGAA
GGCGCCGCGGACCTGCTTCTGGAGCGGGCGCTGGTCGGAGCCTGA

Upstream 100 bases:

>100_bases
GGCCAGATGATCGCGAACACGGGCATGGCCGCAGCCTAAGGGAGAGTCGGGGAGCCGCAAAGGGCGCGGCCGACGACGCG
GACCGCTGTGCCCAGTTTGC

Downstream 100 bases:

>100_bases
ACGGCGCGCTTTACCGTCCTCCGCAGGCGGTGCCATTGAAACCGGGAACGGCCTTCGCTATAGGGGCCACGACGATTCAA
TATGAGGCCACCCGGCCACC

Product: acyl CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 574; Mature: 574

Protein sequence:

>574_residues
MRRVSGALWSQSRPAKRPPSPGRVPMPVSLREATRPPVAGLEAEGFNQPPPFTDVDLLACDAALRDALGAHGPVPAHLRS
AGAEWGSRERMCLGRQANENPPRLHSHDARGQRLDTVEFHPAYHALMAASSAGGLHCATWQGERHLHRAARLYLTAQVEA
GHICPLTMTHAAPAALAAAPELQAEWLGRLTSRLYDGRFLPFWEKTAVTLGMGMTEKQGGTDVRANVTRADRTGGSEYEI
SGHKWFFSAPMCDAFLVLAQAPEGLTTFLMPRFRPDGSVNGLRLQRLKDKLGNRSNASSEVEFDRAFAWRVGAEGRGVAT
ILEMVQLTRLDCAVSSAGLMRRALSEALHNARHRSVFGRRLVVQPAMRLVLADLALEAEAATALAMRLAASFDAAAGSPQ
EAARARLLTPAVKFAVCKAAPDFIYEAMEAVGGNGYVEDSPLPRLFREAPVNAIWEGTGTVVALDLLRAAGRDPQAMALL
LDDLGREAGGLPGVTATIRQVSGLLRDPEPERHARLAAQRIAILAATAALARQAPAAVAEAFARTRLAAGAGLIGTNEVE
GAADLLLERALVGA

Sequences:

>Translated_574_residues
MRRVSGALWSQSRPAKRPPSPGRVPMPVSLREATRPPVAGLEAEGFNQPPPFTDVDLLACDAALRDALGAHGPVPAHLRS
AGAEWGSRERMCLGRQANENPPRLHSHDARGQRLDTVEFHPAYHALMAASSAGGLHCATWQGERHLHRAARLYLTAQVEA
GHICPLTMTHAAPAALAAAPELQAEWLGRLTSRLYDGRFLPFWEKTAVTLGMGMTEKQGGTDVRANVTRADRTGGSEYEI
SGHKWFFSAPMCDAFLVLAQAPEGLTTFLMPRFRPDGSVNGLRLQRLKDKLGNRSNASSEVEFDRAFAWRVGAEGRGVAT
ILEMVQLTRLDCAVSSAGLMRRALSEALHNARHRSVFGRRLVVQPAMRLVLADLALEAEAATALAMRLAASFDAAAGSPQ
EAARARLLTPAVKFAVCKAAPDFIYEAMEAVGGNGYVEDSPLPRLFREAPVNAIWEGTGTVVALDLLRAAGRDPQAMALL
LDDLGREAGGLPGVTATIRQVSGLLRDPEPERHARLAAQRIAILAATAALARQAPAAVAEAFARTRLAAGAGLIGTNEVE
GAADLLLERALVGA
>Mature_574_residues
MRRVSGALWSQSRPAKRPPSPGRVPMPVSLREATRPPVAGLEAEGFNQPPPFTDVDLLACDAALRDALGAHGPVPAHLRS
AGAEWGSRERMCLGRQANENPPRLHSHDARGQRLDTVEFHPAYHALMAASSAGGLHCATWQGERHLHRAARLYLTAQVEA
GHICPLTMTHAAPAALAAAPELQAEWLGRLTSRLYDGRFLPFWEKTAVTLGMGMTEKQGGTDVRANVTRADRTGGSEYEI
SGHKWFFSAPMCDAFLVLAQAPEGLTTFLMPRFRPDGSVNGLRLQRLKDKLGNRSNASSEVEFDRAFAWRVGAEGRGVAT
ILEMVQLTRLDCAVSSAGLMRRALSEALHNARHRSVFGRRLVVQPAMRLVLADLALEAEAATALAMRLAASFDAAAGSPQ
EAARARLLTPAVKFAVCKAAPDFIYEAMEAVGGNGYVEDSPLPRLFREAPVNAIWEGTGTVVALDLLRAAGRDPQAMALL
LDDLGREAGGLPGVTATIRQVSGLLRDPEPERHARLAAQRIAILAATAALARQAPAAVAEAFARTRLAAGAGLIGTNEVE
GAADLLLERALVGA

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=305, Percent_Identity=29.5081967213115, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI226958414, Length=287, Percent_Identity=25.4355400696864, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI226958412, Length=287, Percent_Identity=25.4355400696864, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI187960098, Length=303, Percent_Identity=24.4224422442244, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI4557231, Length=303, Percent_Identity=24.4224422442244, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI4501859, Length=257, Percent_Identity=27.6264591439689, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI4557235, Length=385, Percent_Identity=23.8961038961039, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI76496475, Length=385, Percent_Identity=23.8961038961039, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI21361497, Length=334, Percent_Identity=26.0479041916168, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI7656849, Length=269, Percent_Identity=24.907063197026, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87082384, Length=529, Percent_Identity=44.9905482041588, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI87081958, Length=271, Percent_Identity=24.7232472324723, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI86563383, Length=548, Percent_Identity=32.4817518248175, Blast_Score=211, Evalue=6e-55,
Organism=Caenorhabditis elegans, GI86563381, Length=548, Percent_Identity=32.4817518248175, Blast_Score=211, Evalue=9e-55,
Organism=Caenorhabditis elegans, GI17538396, Length=271, Percent_Identity=28.0442804428044, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17569725, Length=302, Percent_Identity=26.158940397351, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17508101, Length=276, Percent_Identity=26.4492753623188, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17534899, Length=303, Percent_Identity=26.4026402640264, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17506239, Length=257, Percent_Identity=26.8482490272374, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17570075, Length=303, Percent_Identity=25.4125412541254, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71985184, Length=363, Percent_Identity=22.5895316804408, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71990804, Length=220, Percent_Identity=25.4545454545455, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24660351, Length=311, Percent_Identity=26.6881028938907, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21355753, Length=264, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24646207, Length=273, Percent_Identity=27.1062271062271, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI281363737, Length=388, Percent_Identity=23.4536082474227, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356377, Length=257, Percent_Identity=26.4591439688716, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24666513, Length=305, Percent_Identity=25.9016393442623, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 61346; Mature: 61346

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRVSGALWSQSRPAKRPPSPGRVPMPVSLREATRPPVAGLEAEGFNQPPPFTDVDLLAC
CCCCCCHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHH
DAALRDALGAHGPVPAHLRSAGAEWGSRERMCLGRQANENPPRLHSHDARGQRLDTVEFH
HHHHHHHHCCCCCCCHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCEEEEC
PAYHALMAASSAGGLHCATWQGERHLHRAARLYLTAQVEAGHICPLTMTHAAPAALAAAP
HHHHHHHHHCCCCCEEEEECCCHHHHHHHHHEEEEEEECCCCCCCEEECCCCCHHHHCCC
ELQAEWLGRLTSRLYDGRFLPFWEKTAVTLGMGMTEKQGGTDVRANVTRADRTGGSEYEI
HHHHHHHHHHHHHHHCCCCCCCHHHHHHEECCCCCCCCCCCCEEEECCHHCCCCCCEEEE
SGHKWFFSAPMCDAFLVLAQAPEGLTTFLMPRFRPDGSVNGLRLQRLKDKLGNRSNASSE
CCCEEEECCCHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
VEFDRAFAWRVGAEGRGVATILEMVQLTRLDCAVSSAGLMRRALSEALHNARHRSVFGRR
CHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVVQPAMRLVLADLALEAEAATALAMRLAASFDAAAGSPQEAARARLLTPAVKFAVCKAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
PDFIYEAMEAVGGNGYVEDSPLPRLFREAPVNAIWEGTGTVVALDLLRAAGRDPQAMALL
HHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEECCCCHHHHHHHHHHCCCCHHHHHHH
LDDLGREAGGLPGVTATIRQVSGLLRDPEPERHARLAAQRIAILAATAALARQAPAAVAE
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
AFARTRLAAGAGLIGTNEVEGAADLLLERALVGA
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRRVSGALWSQSRPAKRPPSPGRVPMPVSLREATRPPVAGLEAEGFNQPPPFTDVDLLAC
CCCCCCHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHH
DAALRDALGAHGPVPAHLRSAGAEWGSRERMCLGRQANENPPRLHSHDARGQRLDTVEFH
HHHHHHHHCCCCCCCHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCEEEEC
PAYHALMAASSAGGLHCATWQGERHLHRAARLYLTAQVEAGHICPLTMTHAAPAALAAAP
HHHHHHHHHCCCCCEEEEECCCHHHHHHHHHEEEEEEECCCCCCCEEECCCCCHHHHCCC
ELQAEWLGRLTSRLYDGRFLPFWEKTAVTLGMGMTEKQGGTDVRANVTRADRTGGSEYEI
HHHHHHHHHHHHHHHCCCCCCCHHHHHHEECCCCCCCCCCCCEEEECCHHCCCCCCEEEE
SGHKWFFSAPMCDAFLVLAQAPEGLTTFLMPRFRPDGSVNGLRLQRLKDKLGNRSNASSE
CCCEEEECCCHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
VEFDRAFAWRVGAEGRGVATILEMVQLTRLDCAVSSAGLMRRALSEALHNARHRSVFGRR
CHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVVQPAMRLVLADLALEAEAATALAMRLAASFDAAAGSPQEAARARLLTPAVKFAVCKAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
PDFIYEAMEAVGGNGYVEDSPLPRLFREAPVNAIWEGTGTVVALDLLRAAGRDPQAMALL
HHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEECCCCHHHHHHHHHHCCCCHHHHHHH
LDDLGREAGGLPGVTATIRQVSGLLRDPEPERHARLAAQRIAILAATAALARQAPAAVAE
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
AFARTRLAAGAGLIGTNEVEGAADLLLERALVGA
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]