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The map label for this gene is yciL [C]

Identifier: 158424014

GI number: 158424014

Start: 2715554

End: 2717707

Strand: Direct

Name: yciL [C]

Synonym: AZC_2390

Alternate gene names: 158424014

Gene position: 2715554-2717707 (Clockwise)

Preceding gene: 158424011

Following gene: 158424015

Centisome position: 50.57

GC content: 73.58

Gene sequence:

>2154_bases
ATGCCTCGAACATCGCCCCCCCGCAAGGACAAGAACCGCGTTCCCCGCGCCAAGCGCGAGCTGCCCGCCGCTGCGCCCAA
GGAAGCCGAACGCATCGCCAAGGTCATCGCCCGCGCCGGTCTCGGCTCGCGTCGCGAGATTGAAGAGTGGATCACCGCCG
GCCGTGTGTCGGTGAATGGCGAGGTGCTGGCCTCCCCGGCCTTCACCGTGACCGCCGAAGATGAGATTCGCGTGGATGGC
GAGCCGCTGCCCGAGCGCGAGCGCACGCGGCTGTTCCTCTATCACAAGCCCATCGGCGTCGTGACGACCAACCGCGACCC
GGAAGGCCGCACGACCCTGTTCGAGCTTTTGCCCGGGCATCTGCCGCGCCTTGTCTCGGTGGGCCGGCTCGACATCAATT
CCGAAGGCCTGCTGCTGCTGACCAATGACGGGGGCCTCGCCCGCGTTCTGGAACTGCCGGAGACCGGCTGGCTGCGCCGC
TATCGCGTGCGCGCCAAGGGCACGGTGGATCAGGCGCAGCTCGACGCCCTCATCAAGGGCATCGTGGTGGAGGGCGTGGA
GTACGGCCCCATCGAGGCGGTGCTGGACCGGGTGCAGGGCGCAAACGTGTGGATCACGGTGGCGCTGCGCGAAGGCAAGA
ATCGCGAAGTGCGCAACGTGCTCGGCGCGCTCGGCCTTCAGGTGAACCGCCTCATCCGCATCTCCTACGGCCCCTTCCAG
CTGGGCGAGATCGCTGAAGGCGGCGTGGAAGAGGTGCGCACCCGCATCCTGCGCGACCAGATCGGCAACGATATCGCCGC
TGCTGCGGGCGCCGATTTCAACGGTCCGCTTGTCGAGCGCGAGCCTGAGGAGGAGGCCCCCCGCCGCCCCCTCGGCCTCG
ACAAGCGCAAGCTGCCGCGCGCCGCCGAGGTGGCGGACGCCAAGGCGGCGGTCTCCAAGCCGGCCCGCCGCGAGCGTCGC
AGTGCCGAGCCGGAGATCGATCCCGAGCGTCCGCCGCGCGTGCCGCTGCGCAAGCGCATGCAGGACGAGGAACGCAAGGT
GGTGAAGGTGGGCACGGTGGCTGACCGCAAGGGCCGCGCCGTGAAGGTCGAGCGCAAGCTCGCGCCGGTCACGGAAGAGG
CCGTTGAGCGCCGCCCCCGCCGCAAGGCCGACGACGGTCGCGCCTTCGACGCGCCGCGCGGCCGCAGCCGCCGGCCGGAC
TTCGAGGCCGAGGCGGAGGCCCCGCGCGGCCGCCGTCCCGCCGGCGAACGCCCGACCCGCTCGCGCCGGACGGAAGAGGC
CGAATCCATCGGCTTCGCCCAGGCGGCTGAAGGCCCTCGCGCCCGGCGCGCGCCGCGTGGCGAGGGCTTCGCCGACCGCA
AGCCGTCCGACCGGAAAGGCGGCGAGCGCGCCTTCGGCGACCGCAAGGGTGCTGACCGCCGGAGCGAGCGCCCCGAGGGC
CGCGAGAAGGACGTCTATCCCTTCCGCGACAGGATCGAGCGCAGCTCCTGGCGGGCCGACGATGCCGGCCCGAAGCGCCG
CTCCCGCGACGAGGGCGCCGAGCGCCCCGCCCGTGGCGGCTTCGACAAGCCACGCCGCGACCGCGACGATGCCCGCCCCT
TCGGCGGTGACAAGCGCCGGAGCGACAGGCCCTTCGGCAAGCCGGAAGGTGGCCGGGGCCGTCGCGAACAGCCGGCCGAG
GACGTTGGCTTCGGCGGCAGCTTCGAGGGGCGTCCGCCCCGTGGTCGGGGCGGCTTCGCCAAGGACGGCGGGAGCGAGCG
TCCGGCCCGCTTCGGGTTCGACAAGCCCCGTGGCGAGCGTCGCACCGACAAGCCGTTCGGCCGTCCGGAAGGCGGTCGCA
CCCGCCGCGAGCAGCCGGCCGGAGAAGGCGGGTTCGAGGGGCGTGCGCCCCGCGGCCGTGGCGGATTCGCCAAAGAGGGC
GCAAGTGAGCGCCCGGCCCGTTCCGGCTTCGACAAGCCGCGCGGCGAGCGCAGCTTCGGCAAAAGCGAAGGCCGTCCGCC
TCGCGAAGACCGTTCCCCCGGCGGCAAGCCCGCAGGCAAGCGGCCGGGCTTCGGCGCCGGCCCGCGCACGGGCGCGCCCA
AGGGGCGGCCCGGTGGCGGCAAGGGCGGCCCGGCACGCGGCGGCAAGCCGCAAGGTCCGCGTTCGCGCGGCTGA

Upstream 100 bases:

>100_bases
CGGCGGCGCGGGCCTCGGAAAGGGCCGTCTGCATGAAAGTCTCGCTCACCGGATGCCCCGCGATCTCGTCTCGCCGCACG
GTTCGTGCTATCGCCCCTCC

Downstream 100 bases:

>100_bases
TCCATGCGGATCGTCGGCGGCAAGCATCGCGGGCGCCCTCTTCAGGCGCCCGCTTCCAAGGCGACGCGGCCGACCACGGA
CCGGCTGCGCGAGAGCCTCT

Product: pseudouridine synthase

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 717; Mature: 716

Protein sequence:

>717_residues
MPRTSPPRKDKNRVPRAKRELPAAAPKEAERIAKVIARAGLGSRREIEEWITAGRVSVNGEVLASPAFTVTAEDEIRVDG
EPLPERERTRLFLYHKPIGVVTTNRDPEGRTTLFELLPGHLPRLVSVGRLDINSEGLLLLTNDGGLARVLELPETGWLRR
YRVRAKGTVDQAQLDALIKGIVVEGVEYGPIEAVLDRVQGANVWITVALREGKNREVRNVLGALGLQVNRLIRISYGPFQ
LGEIAEGGVEEVRTRILRDQIGNDIAAAAGADFNGPLVEREPEEEAPRRPLGLDKRKLPRAAEVADAKAAVSKPARRERR
SAEPEIDPERPPRVPLRKRMQDEERKVVKVGTVADRKGRAVKVERKLAPVTEEAVERRPRRKADDGRAFDAPRGRSRRPD
FEAEAEAPRGRRPAGERPTRSRRTEEAESIGFAQAAEGPRARRAPRGEGFADRKPSDRKGGERAFGDRKGADRRSERPEG
REKDVYPFRDRIERSSWRADDAGPKRRSRDEGAERPARGGFDKPRRDRDDARPFGGDKRRSDRPFGKPEGGRGRREQPAE
DVGFGGSFEGRPPRGRGGFAKDGGSERPARFGFDKPRGERRTDKPFGRPEGGRTRREQPAGEGGFEGRAPRGRGGFAKEG
ASERPARSGFDKPRGERSFGKSEGRPPREDRSPGGKPAGKRPGFGAGPRTGAPKGRPGGGKGGPARGGKPQGPRSRG

Sequences:

>Translated_717_residues
MPRTSPPRKDKNRVPRAKRELPAAAPKEAERIAKVIARAGLGSRREIEEWITAGRVSVNGEVLASPAFTVTAEDEIRVDG
EPLPERERTRLFLYHKPIGVVTTNRDPEGRTTLFELLPGHLPRLVSVGRLDINSEGLLLLTNDGGLARVLELPETGWLRR
YRVRAKGTVDQAQLDALIKGIVVEGVEYGPIEAVLDRVQGANVWITVALREGKNREVRNVLGALGLQVNRLIRISYGPFQ
LGEIAEGGVEEVRTRILRDQIGNDIAAAAGADFNGPLVEREPEEEAPRRPLGLDKRKLPRAAEVADAKAAVSKPARRERR
SAEPEIDPERPPRVPLRKRMQDEERKVVKVGTVADRKGRAVKVERKLAPVTEEAVERRPRRKADDGRAFDAPRGRSRRPD
FEAEAEAPRGRRPAGERPTRSRRTEEAESIGFAQAAEGPRARRAPRGEGFADRKPSDRKGGERAFGDRKGADRRSERPEG
REKDVYPFRDRIERSSWRADDAGPKRRSRDEGAERPARGGFDKPRRDRDDARPFGGDKRRSDRPFGKPEGGRGRREQPAE
DVGFGGSFEGRPPRGRGGFAKDGGSERPARFGFDKPRGERRTDKPFGRPEGGRTRREQPAGEGGFEGRAPRGRGGFAKEG
ASERPARSGFDKPRGERSFGKSEGRPPREDRSPGGKPAGKRPGFGAGPRTGAPKGRPGGGKGGPARGGKPQGPRSRG
>Mature_716_residues
PRTSPPRKDKNRVPRAKRELPAAAPKEAERIAKVIARAGLGSRREIEEWITAGRVSVNGEVLASPAFTVTAEDEIRVDGE
PLPERERTRLFLYHKPIGVVTTNRDPEGRTTLFELLPGHLPRLVSVGRLDINSEGLLLLTNDGGLARVLELPETGWLRRY
RVRAKGTVDQAQLDALIKGIVVEGVEYGPIEAVLDRVQGANVWITVALREGKNREVRNVLGALGLQVNRLIRISYGPFQL
GEIAEGGVEEVRTRILRDQIGNDIAAAAGADFNGPLVEREPEEEAPRRPLGLDKRKLPRAAEVADAKAAVSKPARRERRS
AEPEIDPERPPRVPLRKRMQDEERKVVKVGTVADRKGRAVKVERKLAPVTEEAVERRPRRKADDGRAFDAPRGRSRRPDF
EAEAEAPRGRRPAGERPTRSRRTEEAESIGFAQAAEGPRARRAPRGEGFADRKPSDRKGGERAFGDRKGADRRSERPEGR
EKDVYPFRDRIERSSWRADDAGPKRRSRDEGAERPARGGFDKPRRDRDDARPFGGDKRRSDRPFGKPEGGRGRREQPAED
VGFGGSFEGRPPRGRGGFAKDGGSERPARFGFDKPRGERRTDKPFGRPEGGRTRREQPAGEGGFEGRAPRGRGGFAKEGA
SERPARSGFDKPRGERSFGKSEGRPPREDRSPGGKPAGKRPGFGAGPRTGAPKGRPGGGKGGPARGGKPQGPRSRG

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=224, Percent_Identity=45.0892857142857, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI87081838, Length=186, Percent_Identity=34.9462365591398, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788510, Length=204, Percent_Identity=30.8823529411765, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790453, Length=227, Percent_Identity=29.0748898678414, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR000748
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 78934; Mature: 78802

Theoretical pI: Translated: 11.46; Mature: 11.46

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.1 %Met     (Mature Protein)
0.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRTSPPRKDKNRVPRAKRELPAAAPKEAERIAKVIARAGLGSRREIEEWITAGRVSVNG
CCCCCCCCCCHHHCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEECC
EVLASPAFTVTAEDEIRVDGEPLPERERTRLFLYHKPIGVVTTNRDPEGRTTLFELLPGH
EEEECCCEEEECCCCEEECCCCCCCCCCCEEEEEECCEEEEECCCCCCCHHHHHHHHHHH
LPRLVSVGRLDINSEGLLLLTNDGGLARVLELPETGWLRRYRVRAKGTVDQAQLDALIKG
HHHHHHHCCEEECCCCEEEEECCCCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHH
IVVEGVEYGPIEAVLDRVQGANVWITVALREGKNREVRNVLGALGLQVNRLIRISYGPFQ
HHHCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCEEEEEEEECCCCC
LGEIAEGGVEEVRTRILRDQIGNDIAAAAGADFNGPLVEREPEEEAPRRPLGLDKRKLPR
HHHHHCCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCHHHCCC
AAEVADAKAAVSKPARRERRSAEPEIDPERPPRVPLRKRMQDEERKVVKVGTVADRKGRA
HHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCEEEECCCCCCCCCE
VKVERKLAPVTEEAVERRPRRKADDGRAFDAPRGRSRRPDFEAEAEAPRGRRPAGERPTR
EEEHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
SRRTEEAESIGFAQAAEGPRARRAPRGEGFADRKPSDRKGGERAFGDRKGADRRSERPEG
HHHHHHHHHHCCHHHCCCCHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHCCCCCC
REKDVYPFRDRIERSSWRADDAGPKRRSRDEGAERPARGGFDKPRRDRDDARPFGGDKRR
CCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCCC
SDRPFGKPEGGRGRREQPAEDVGFGGSFEGRPPRGRGGFAKDGGSERPARFGFDKPRGER
CCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RTDKPFGRPEGGRTRREQPAGEGGFEGRAPRGRGGFAKEGASERPARSGFDKPRGERSFG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCC
KSEGRPPREDRSPGGKPAGKRPGFGAGPRTGAPKGRPGGGKGGPARGGKPQGPRSRG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PRTSPPRKDKNRVPRAKRELPAAAPKEAERIAKVIARAGLGSRREIEEWITAGRVSVNG
CCCCCCCCCHHHCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEECC
EVLASPAFTVTAEDEIRVDGEPLPERERTRLFLYHKPIGVVTTNRDPEGRTTLFELLPGH
EEEECCCEEEECCCCEEECCCCCCCCCCCEEEEEECCEEEEECCCCCCCHHHHHHHHHHH
LPRLVSVGRLDINSEGLLLLTNDGGLARVLELPETGWLRRYRVRAKGTVDQAQLDALIKG
HHHHHHHCCEEECCCCEEEEECCCCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHH
IVVEGVEYGPIEAVLDRVQGANVWITVALREGKNREVRNVLGALGLQVNRLIRISYGPFQ
HHHCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCEEEEEEEECCCCC
LGEIAEGGVEEVRTRILRDQIGNDIAAAAGADFNGPLVEREPEEEAPRRPLGLDKRKLPR
HHHHHCCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCHHHCCC
AAEVADAKAAVSKPARRERRSAEPEIDPERPPRVPLRKRMQDEERKVVKVGTVADRKGRA
HHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCEEEECCCCCCCCCE
VKVERKLAPVTEEAVERRPRRKADDGRAFDAPRGRSRRPDFEAEAEAPRGRRPAGERPTR
EEEHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
SRRTEEAESIGFAQAAEGPRARRAPRGEGFADRKPSDRKGGERAFGDRKGADRRSERPEG
HHHHHHHHHHCCHHHCCCCHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHCCCCCC
REKDVYPFRDRIERSSWRADDAGPKRRSRDEGAERPARGGFDKPRRDRDDARPFGGDKRR
CCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCCC
SDRPFGKPEGGRGRREQPAEDVGFGGSFEGRPPRGRGGFAKDGGSERPARFGFDKPRGER
CCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RTDKPFGRPEGGRTRREQPAGEGGFEGRAPRGRGGFAKEGASERPARSGFDKPRGERSFG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCC
KSEGRPPREDRSPGGKPAGKRPGFGAGPRTGAPKGRPGGGKGGPARGGKPQGPRSRG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]