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The map label for this gene is waaA [H]

Identifier: 158424006

GI number: 158424006

Start: 2707674

End: 2708969

Strand: Direct

Name: waaA [H]

Synonym: AZC_2382

Alternate gene names: 158424006

Gene position: 2707674-2708969 (Clockwise)

Preceding gene: 158424005

Following gene: 158424007

Centisome position: 50.42

GC content: 70.99

Gene sequence:

>1296_bases
ATGACCCGACGGCCGCTCCCGGTTCCGCTCCGCCTCTACCGGGGCGCCGCCTCGTTCGCGACGGTGCTGGCCCCGGCCTG
GCTGAAGTACCGGGTACGCAAGGGCAAGGAAGACCCGGCACGCATCGCCGAGCGGCGCGGCATCACGCGGGTGGAGCGGC
CGCAGGGTCCGCTCATCTGGGTCCATGGGGCGAGCGTCGGCGAGATCGTCTCCATTCTGCCCCTCGTGGAGCGGCTTCAG
GATCGCGGTTTCGCCATCCTGCTCACCTCGGGCACGCTCACCTCGAGCCGCGTCGCCGCCCGTCGGGCGCCGGCCTCGGT
GATCCACCAGTTCGTCCCCCTCGACGCCCCCGCCTTCGTGCGCCGCTTCCTCGACCACTGGAAGCCCGATCTCGCGCTGC
TGGCGGAATCCGAGCTCTGGCCCAACCTCATGACCGAGCTCGACAAGCGCGGCACGGCGGTTGTGCTTGTGAACGGCCGT
CTGTCCGCCCGTTCAGCGCAGCGCTGGGCCCGCCTGCCCCGCAGCGCGCGGGCGCTCCTTTCGCGCGTCGATCTCTGCCT
CGCCCAGACGCCCGAGGATGCCGCACGTTTCCGGGGCCTTGGCGCGCCGCGCGTTCAGGTCGCCGGCAATCTCAAGTTCG
ACGTTCCGGCGCCGCCCGCCGACCCCAGCATGCTCGCCCGCCTCCAGGCCGCCATCGGCGAGCGTCCCGTCCTGCTCGCG
GCCTCGACGCATCCGGGCGAGGACGAATACGTTCTGGAAGCGCACGGGCGGCTGCGGCAGGACCTGCCGGGCCTTCTCAC
CATCATCGCCCCCCGTCATCCCGAGCGCGGCGGTGCCATCCGCCAGCTGGCCCACGACGCGGGATTTGCGGCCACCCAGC
GCAGCCAGGCCCCGCTCCCGCTGCCCGAGGCGGAGGTCTATGTGGCCGACACCATCGGCGAGATGGGTCTGTTCTATCGG
GTCGCTCCGGTCGCCTTCCTCGGCGGCTCGCTGATCGAGCATGGCGGGCAGAACCCCATCGAGCCCGCCAAGATCGGCAC
GGTGGTGCTGCACGGTCCGCATGTGTGGAATTTCGCTGCCGTCTATGGCCGGCTGGACGAGGCCGCCGGCTCCGTCCCGG
TGATGGATGCCGAGGACATCGTGCGCGCCACGCTCGACATCTTCTTCACGCCCGGCTGCCACGAGCGCATCTCCCACGCC
GCCTGGCAGACGGTGGAAAACCTCAGCGGTGCGCTGCCGCGCACGCTGGCGGCCATCGAGCCCTATCTCCTGCAGATCCG
GCTGGAAGGGAAATGA

Upstream 100 bases:

>100_bases
AGCGGCGCCTCGAAGCCGCGACGGCCCGTGCCGAGGCGCTGGTGGGACGCGGCAGCGCCCCGGCCCTCATCGACGGCAGG
GCCCCCGGCGAGGCCGCCCG

Downstream 100 bases:

>100_bases
TCGGGCAGGCGCCCGCCTTCTGGTCCCGCCGCAACAGCCTCATGGGCTGGGTGCTCTCGCCGATCGGCGCGCTTGTCGGC
GCCCTCACCCTGAAGCGGAT

Product: 3-deoxy-D-manno-octulosonic acid transferase-like protein

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MTRRPLPVPLRLYRGAASFATVLAPAWLKYRVRKGKEDPARIAERRGITRVERPQGPLIWVHGASVGEIVSILPLVERLQ
DRGFAILLTSGTLTSSRVAARRAPASVIHQFVPLDAPAFVRRFLDHWKPDLALLAESELWPNLMTELDKRGTAVVLVNGR
LSARSAQRWARLPRSARALLSRVDLCLAQTPEDAARFRGLGAPRVQVAGNLKFDVPAPPADPSMLARLQAAIGERPVLLA
ASTHPGEDEYVLEAHGRLRQDLPGLLTIIAPRHPERGGAIRQLAHDAGFAATQRSQAPLPLPEAEVYVADTIGEMGLFYR
VAPVAFLGGSLIEHGGQNPIEPAKIGTVVLHGPHVWNFAAVYGRLDEAAGSVPVMDAEDIVRATLDIFFTPGCHERISHA
AWQTVENLSGALPRTLAAIEPYLLQIRLEGK

Sequences:

>Translated_431_residues
MTRRPLPVPLRLYRGAASFATVLAPAWLKYRVRKGKEDPARIAERRGITRVERPQGPLIWVHGASVGEIVSILPLVERLQ
DRGFAILLTSGTLTSSRVAARRAPASVIHQFVPLDAPAFVRRFLDHWKPDLALLAESELWPNLMTELDKRGTAVVLVNGR
LSARSAQRWARLPRSARALLSRVDLCLAQTPEDAARFRGLGAPRVQVAGNLKFDVPAPPADPSMLARLQAAIGERPVLLA
ASTHPGEDEYVLEAHGRLRQDLPGLLTIIAPRHPERGGAIRQLAHDAGFAATQRSQAPLPLPEAEVYVADTIGEMGLFYR
VAPVAFLGGSLIEHGGQNPIEPAKIGTVVLHGPHVWNFAAVYGRLDEAAGSVPVMDAEDIVRATLDIFFTPGCHERISHA
AWQTVENLSGALPRTLAAIEPYLLQIRLEGK
>Mature_430_residues
TRRPLPVPLRLYRGAASFATVLAPAWLKYRVRKGKEDPARIAERRGITRVERPQGPLIWVHGASVGEIVSILPLVERLQD
RGFAILLTSGTLTSSRVAARRAPASVIHQFVPLDAPAFVRRFLDHWKPDLALLAESELWPNLMTELDKRGTAVVLVNGRL
SARSAQRWARLPRSARALLSRVDLCLAQTPEDAARFRGLGAPRVQVAGNLKFDVPAPPADPSMLARLQAAIGERPVLLAA
STHPGEDEYVLEAHGRLRQDLPGLLTIIAPRHPERGGAIRQLAHDAGFAATQRSQAPLPLPEAEVYVADTIGEMGLFYRV
APVAFLGGSLIEHGGQNPIEPAKIGTVVLHGPHVWNFAAVYGRLDEAAGSVPVMDAEDIVRATLDIFFTPGCHERISHAA
WQTVENLSGALPRTLAAIEPYLLQIRLEGK

Specific function: Essential step in lipopolysaccharides biosynthesis. Acts at transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA). Transfers two molecules of KDO to lipid IVA [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=407, Percent_Identity=40.2948402948403, Blast_Score=255, Evalue=3e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR007507 [H]

Pfam domain/function: PF00534 Glycos_transf_1; PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 46984; Mature: 46853

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRPLPVPLRLYRGAASFATVLAPAWLKYRVRKGKEDPARIAERRGITRVERPQGPLIW
CCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCEEE
VHGASVGEIVSILPLVERLQDRGFAILLTSGTLTSSRVAARRAPASVIHQFVPLDAPAFV
EECCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCHHHHHHHCCCCCHHHH
RRFLDHWKPDLALLAESELWPNLMTELDKRGTAVVLVNGRLSARSAQRWARLPRSARALL
HHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCHHHHHHH
SRVDLCLAQTPEDAARFRGLGAPRVQVAGNLKFDVPAPPADPSMLARLQAAIGERPVLLA
HHHHHHHHCCCHHHHHHCCCCCCCEEEECCEEECCCCCCCCHHHHHHHHHHHCCCCEEEE
ASTHPGEDEYVLEAHGRLRQDLPGLLTIIAPRHPERGGAIRQLAHDAGFAATQRSQAPLP
ECCCCCCCCEEEHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCC
LPEAEVYVADTIGEMGLFYRVAPVAFLGGSLIEHGGQNPIEPAKIGTVVLHGPHVWNFAA
CCCCCEEEEHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHCEEEEECCCHHHHHH
VYGRLDEAAGSVPVMDAEDIVRATLDIFFTPGCHERISHAAWQTVENLSGALPRTLAAIE
HHHHHHHHCCCCCCCCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHC
PYLLQIRLEGK
CEEEEEEECCC
>Mature Secondary Structure 
TRRPLPVPLRLYRGAASFATVLAPAWLKYRVRKGKEDPARIAERRGITRVERPQGPLIW
CCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCEEE
VHGASVGEIVSILPLVERLQDRGFAILLTSGTLTSSRVAARRAPASVIHQFVPLDAPAFV
EECCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCHHHHHHHCCCCCHHHH
RRFLDHWKPDLALLAESELWPNLMTELDKRGTAVVLVNGRLSARSAQRWARLPRSARALL
HHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCHHHHHHH
SRVDLCLAQTPEDAARFRGLGAPRVQVAGNLKFDVPAPPADPSMLARLQAAIGERPVLLA
HHHHHHHHCCCHHHHHHCCCCCCCEEEECCEEECCCCCCCCHHHHHHHHHHHCCCCEEEE
ASTHPGEDEYVLEAHGRLRQDLPGLLTIIAPRHPERGGAIRQLAHDAGFAATQRSQAPLP
ECCCCCCCCEEEHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCC
LPEAEVYVADTIGEMGLFYRVAPVAFLGGSLIEHGGQNPIEPAKIGTVVLHGPHVWNFAA
CCCCCEEEEHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHCEEEEECCCHHHHHH
VYGRLDEAAGSVPVMDAEDIVRATLDIFFTPGCHERISHAAWQTVENLSGALPRTLAAIE
HHHHHHHHCCCCCCCCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHC
PYLLQIRLEGK
CEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]