BacMap

Definition	Azorhizobium caulinodans ORS 571, complete genome.
Accession	NC_009937
Length	5,369,772

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The map label for this gene is fabG [H]

Identifier: 158423965

GI number: 158423965

Start: 2667254

End: 2667970

Strand: Direct

Name: fabG [H]

Synonym: AZC_2341

Alternate gene names: 158423965

Gene position: 2667254-2667970 (Clockwise)

Preceding gene: 158423964

Following gene: 158423966

Centisome position: 49.67

GC content: 70.71

Gene sequence:

>717_bases
ATGACGGACCGCACGCTGGTCACAGGCGGAGCGGGCGGCATCGGCCTCGCGGTGGCCCGGCAGGAGCGCATGGCCGGCCG
TGCGGTGGTGGTGCTGGACCGCGAGCCGCCGCCCGACCTTGAGGCCCGCTTCCTCTGCGTGGACCTGATGAGCGAGGCGG
CGACTGCGCAGGCGCTCACCGAGGCGCTCTCCGAGGGCCCGATCACCCGCCTCGTGAACAATGTGGGCATGGTGCGCCCT
GCCAGCCTCGATGACACGACGGCGGAGGATTTCGCAGCCGTCATGCGGCTCAATCTCGGCGTCGCCATTCAGGTCACGCA
GGCGCTGGTGCCCGGCATGCGGGCCGCCCGCTTCGGCCGCATCGTCAATGTGTCCAGCCGCGCAGCCTATGGCAAGGAAC
TGCGCACCGCTTACGCCGCCAGCAAGGCCGGCCTTCTCGGCGCCACCCGCACCTGGGCTCTGGAACTGGGGCGGGACGGC
ATCACGGTGAACGCCGTGGCGCCCGGACCCATTGCAACGCCGCTGTTCACCGCAGCCAACCCGCCGGATGCTCCCCGCAC
CCGCGCCATCGTGGAGGCAATCCCCGTGGGCCGCATGGGCACGCCGGAAGATGTGGCGCAGGCCGTGAGCTTCTTCCTCG
GCGAATCTGCCGGCTTCATCACCGGCCAGACGCTGCCGGTCTGCGGCGGAATCACCGTTGGCAAGGGCGCGAACTGA

Upstream 100 bases:

>100_bases
CAGTTGATCCCTTCTTCACCGCAGGCCTGTTCGAACGCGTTCAGATCACCCGCTGGCGCAAGGCCTATGTGGATGGCGTG
TGCTATCTGCCGGAGGCGAA

Downstream 100 bases:

>100_bases
GGCCAATGCCCCATAGGGAGAACACCATGTCGTCCGATCGCCGCTGGGTCCGCCGTCCGGAAGGCTCCACCTGGGGCGAT
TTTGGTCCGGACGACGAACT

Product: NAD-dependent epimerase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MTDRTLVTGGAGGIGLAVARQERMAGRAVVVLDREPPPDLEARFLCVDLMSEAATAQALTEALSEGPITRLVNNVGMVRP
ASLDDTTAEDFAAVMRLNLGVAIQVTQALVPGMRAARFGRIVNVSSRAAYGKELRTAYAASKAGLLGATRTWALELGRDG
ITVNAVAPGPIATPLFTAANPPDAPRTRAIVEAIPVGRMGTPEDVAQAVSFFLGESAGFITGQTLPVCGGITVGKGAN

Sequences:

>Translated_238_residues
MTDRTLVTGGAGGIGLAVARQERMAGRAVVVLDREPPPDLEARFLCVDLMSEAATAQALTEALSEGPITRLVNNVGMVRP
ASLDDTTAEDFAAVMRLNLGVAIQVTQALVPGMRAARFGRIVNVSSRAAYGKELRTAYAASKAGLLGATRTWALELGRDG
ITVNAVAPGPIATPLFTAANPPDAPRTRAIVEAIPVGRMGTPEDVAQAVSFFLGESAGFITGQTLPVCGGITVGKGAN
>Mature_237_residues
TDRTLVTGGAGGIGLAVARQERMAGRAVVVLDREPPPDLEARFLCVDLMSEAATAQALTEALSEGPITRLVNNVGMVRPA
SLDDTTAEDFAAVMRLNLGVAIQVTQALVPGMRAARFGRIVNVSSRAAYGKELRTAYAASKAGLLGATRTWALELGRDGI
TVNAVAPGPIATPLFTAANPPDAPRTRAIVEAIPVGRMGTPEDVAQAVSFFLGESAGFITGQTLPVCGGITVGKGAN

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=37.4501992031873, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI7705925, Length=238, Percent_Identity=34.453781512605, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=35.1020408163265, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI19923817, Length=246, Percent_Identity=30.0813008130081, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI59889578, Length=242, Percent_Identity=32.6446280991736, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI40254992, Length=238, Percent_Identity=32.3529411764706, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI66933014, Length=206, Percent_Identity=26.2135922330097, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI5031737, Length=239, Percent_Identity=31.3807531380753, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4503817, Length=224, Percent_Identity=27.6785714285714, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI4504505, Length=153, Percent_Identity=32.0261437908497, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI126723750, Length=93, Percent_Identity=39.7849462365591, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=238, Percent_Identity=32.7731092436975, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI87082100, Length=246, Percent_Identity=32.1138211382114, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1789208, Length=237, Percent_Identity=32.4894514767932, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI87082160, Length=242, Percent_Identity=30.5785123966942, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1790717, Length=243, Percent_Identity=27.9835390946502, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786812, Length=242, Percent_Identity=30.9917355371901, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787905, Length=238, Percent_Identity=31.5126050420168, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788459, Length=171, Percent_Identity=34.5029239766082, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=29.718875502008, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789057, Length=186, Percent_Identity=26.8817204301075, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI2367365, Length=236, Percent_Identity=28.3898305084746, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=28.4584980237154, Blast_Score=68, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=243, Percent_Identity=34.5679012345679, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17555706, Length=239, Percent_Identity=33.0543933054393, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=32.258064516129, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=253, Percent_Identity=28.8537549407115, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI115534694, Length=240, Percent_Identity=29.5833333333333, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=29.2307692307692, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=260, Percent_Identity=29.2307692307692, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=30.4832713754647, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17561402, Length=244, Percent_Identity=27.4590163934426, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=262, Percent_Identity=31.6793893129771, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=257, Percent_Identity=30.7392996108949, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=184, Percent_Identity=33.695652173913, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=29.8850574712644, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=190, Percent_Identity=32.6315789473684, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=183, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=245, Percent_Identity=30.2040816326531, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=27.6923076923077, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=268, Percent_Identity=26.865671641791, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=256, Percent_Identity=28.515625, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=257, Percent_Identity=27.6264591439689, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=259, Percent_Identity=30.5019305019305, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=27.9245283018868, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=26.5384615384615, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=257, Percent_Identity=27.2373540856031, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=187, Percent_Identity=32.0855614973262, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24643142, Length=238, Percent_Identity=31.9327731092437, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24639444, Length=241, Percent_Identity=32.7800829875519, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=31.404958677686, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI23397609, Length=240, Percent_Identity=32.9166666666667, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24644339, Length=247, Percent_Identity=31.5789473684211, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=31.6, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357041, Length=191, Percent_Identity=35.0785340314136, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24644337, Length=209, Percent_Identity=35.4066985645933, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356301, Length=224, Percent_Identity=28.125, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI18859837, Length=104, Percent_Identity=35.5769230769231, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24525; Mature: 24393

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRTLVTGGAGGIGLAVARQERMAGRAVVVLDREPPPDLEARFLCVDLMSEAATAQALT
CCCCEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
EALSEGPITRLVNNVGMVRPASLDDTTAEDFAAVMRLNLGVAIQVTQALVPGMRAARFGR
HHHHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEHHHHHCCHHHHHHCC
IVNVSSRAAYGKELRTAYAASKAGLLGATRTWALELGRDGITVNAVAPGPIATPLFTAAN
EEECCHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEECCCCEEEEEECCCCCCCCEEECCC
PPDAPRTRAIVEAIPVGRMGTPEDVAQAVSFFLGESAGFITGQTLPVCGGITVGKGAN
CCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCEECCEECCCCCC
>Mature Secondary Structure 
TDRTLVTGGAGGIGLAVARQERMAGRAVVVLDREPPPDLEARFLCVDLMSEAATAQALT
CCCEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
EALSEGPITRLVNNVGMVRPASLDDTTAEDFAAVMRLNLGVAIQVTQALVPGMRAARFGR
HHHHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEHHHHHCCHHHHHHCC
IVNVSSRAAYGKELRTAYAASKAGLLGATRTWALELGRDGITVNAVAPGPIATPLFTAAN
EEECCHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEECCCCEEEEEECCCCCCCCEEECCC
PPDAPRTRAIVEAIPVGRMGTPEDVAQAVSFFLGESAGFITGQTLPVCGGITVGKGAN
CCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCEECCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]