Click here to switch to the map view.

The map label for this gene is ycgM [C]

Identifier: 158423926

GI number: 158423926

Start: 2626716

End: 2627564

Strand: Direct

Name: ycgM [C]

Synonym: AZC_2302

Alternate gene names: 158423926

Gene position: 2626716-2627564 (Clockwise)

Preceding gene: 158423922

Following gene: 158423935

Centisome position: 48.92

GC content: 65.37

Gene sequence:

>849_bases
ATGAAGCTCGTCCGCTTCGGCGCCCCAGGTCAGGAAAAGCCGGGTCTAATCGATTCAAGCGGGAAGATCCGCGACCTGTC
CGGCGTCGTCTCCGACATTGGCGGCGAGGTTCTCACCCGCGCCGGTCTTGCCAAGATCGCGGCCCTCGATCCCGCCGGCC
TGCCGCTGGCGCCCGAGGGCGTGCGCCTCGGCTCCTGCGTGGCGCGGCCCGGCAACTTCATCGCCGTGGGCCTCAATTAT
GCGGACCACGCGGCCGAAACGAACAATCCGATTCCCGAGGAGCCGGTGCTGTTCAACAAGGCGCCGAACTGCGTGGTCGG
CCCCAATGACGACGTGATGGTCCCCAAGAATTCCCAGAAACTCGACTGGGAAGTGGAACTGGTCATCGTCATCGGCGACC
GCGCCCGCTATGTGGACGAGAAGGACGCCCTCAAGCACGTCGCCGGCTACACGATCTGCAACGACGTGTCCGAGCGTCAC
TTCCAGATCGAGCGCGCCGGCCAGTGGACCAAGGGCAAGGGCAGCGAGACCTTCGGCCCGCTCGGCCCCTGGATGGTCAC
CACGGACGAACTGACCGACACCTCCAGCCTCGGCATGTGGCTCGAGGTGAACGGCGAACGGGTGCAGAACGGCTCGACGA
AGACGATGATCTTCAACGTCGCCTATCTCGTCTCCTACATCAGCCAGTTCATGGTGCTCGATCCCGGCGACATCATCACC
ACCGGCACCCCGCCCGGCGTCGGCCTCGGCTTCAAGCCGCCGCGCTATCTGAAGGCGGGCGACGTGGTGCGCCTTGGCAT
CGACGGCCTCGGCGAGCAGCAGCAGACCATCGTGCCGTTCAAGCTCTGA

Upstream 100 bases:

>100_bases
CTGCCGTGGCCGAGCCCATTGACCAAACGGGCGCTCCGGGCCAGCTTGCCGCCCCTCCGCCCGTCCGCGGTGCGGCATAA
TTCCCAAGGGAGAAACATCC

Downstream 100 bases:

>100_bases
GCTTGTCCTGACGAAGTGAAAATGAGGGCCGCCGACGCCCCGGCGGCCCTTTTTGTTTGGCGGCCCCGCCTCACTGGAGC
GTGGCGTGAGCGAGCCAGGT

Product: 2-keto-4-pentenoate hydratase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MKLVRFGAPGQEKPGLIDSSGKIRDLSGVVSDIGGEVLTRAGLAKIAALDPAGLPLAPEGVRLGSCVARPGNFIAVGLNY
ADHAAETNNPIPEEPVLFNKAPNCVVGPNDDVMVPKNSQKLDWEVELVIVIGDRARYVDEKDALKHVAGYTICNDVSERH
FQIERAGQWTKGKGSETFGPLGPWMVTTDELTDTSSLGMWLEVNGERVQNGSTKTMIFNVAYLVSYISQFMVLDPGDIIT
TGTPPGVGLGFKPPRYLKAGDVVRLGIDGLGEQQQTIVPFKL

Sequences:

>Translated_282_residues
MKLVRFGAPGQEKPGLIDSSGKIRDLSGVVSDIGGEVLTRAGLAKIAALDPAGLPLAPEGVRLGSCVARPGNFIAVGLNY
ADHAAETNNPIPEEPVLFNKAPNCVVGPNDDVMVPKNSQKLDWEVELVIVIGDRARYVDEKDALKHVAGYTICNDVSERH
FQIERAGQWTKGKGSETFGPLGPWMVTTDELTDTSSLGMWLEVNGERVQNGSTKTMIFNVAYLVSYISQFMVLDPGDIIT
TGTPPGVGLGFKPPRYLKAGDVVRLGIDGLGEQQQTIVPFKL
>Mature_282_residues
MKLVRFGAPGQEKPGLIDSSGKIRDLSGVVSDIGGEVLTRAGLAKIAALDPAGLPLAPEGVRLGSCVARPGNFIAVGLNY
ADHAAETNNPIPEEPVLFNKAPNCVVGPNDDVMVPKNSQKLDWEVELVIVIGDRARYVDEKDALKHVAGYTICNDVSERH
FQIERAGQWTKGKGSETFGPLGPWMVTTDELTDTSSLGMWLEVNGERVQNGSTKTMIFNVAYLVSYISQFMVLDPGDIIT
TGTPPGVGLGFKPPRYLKAGDVVRLGIDGLGEQQQTIVPFKL

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=222, Percent_Identity=47.2972972972973, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI40786394, Length=222, Percent_Identity=45.945945945946, Blast_Score=209, Evalue=2e-54,
Organism=Homo sapiens, GI215422413, Length=214, Percent_Identity=36.4485981308411, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI66348062, Length=211, Percent_Identity=37.4407582938389, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI13654274, Length=202, Percent_Identity=37.6237623762376, Blast_Score=138, Evalue=7e-33,
Organism=Escherichia coli, GI1787428, Length=199, Percent_Identity=34.6733668341709, Blast_Score=118, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17557057, Length=197, Percent_Identity=34.010152284264, Blast_Score=123, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6324161, Length=226, Percent_Identity=28.7610619469027, Blast_Score=86, Evalue=9e-18,
Organism=Drosophila melanogaster, GI28572127, Length=276, Percent_Identity=40.5797101449275, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24663695, Length=218, Percent_Identity=33.9449541284404, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI28571789, Length=203, Percent_Identity=35.9605911330049, Blast_Score=127, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 30271; Mature: 30271

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVRFGAPGQEKPGLIDSSGKIRDLSGVVSDIGGEVLTRAGLAKIAALDPAGLPLAPEG
CCEEEECCCCCCCCCEECCCCCEEHHHHHHHHHCHHHHHHHHHHHEEEECCCCCCCCCCC
VRLGSCVARPGNFIAVGLNYADHAAETNNPIPEEPVLFNKAPNCVVGPNDDVMVPKNSQK
CEECCEECCCCCEEEEECCCHHHHHCCCCCCCCCCEEECCCCCEEECCCCCEEECCCCCC
LDWEVELVIVIGDRARYVDEKDALKHVAGYTICNDVSERHFQIERAGQWTKGKGSETFGP
CCEEEEEEEEECCCCHHCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCC
LGPWMVTTDELTDTSSLGMWLEVNGERVQNGSTKTMIFNVAYLVSYISQFMVLDPGDIIT
CCCEEEEECCCCCCCCCEEEEEECCCEECCCCCEEEEHHHHHHHHHHHHHEEECCCCEEE
TGTPPGVGLGFKPPRYLKAGDVVRLGIDGLGEQQQTIVPFKL
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEECCCC
>Mature Secondary Structure
MKLVRFGAPGQEKPGLIDSSGKIRDLSGVVSDIGGEVLTRAGLAKIAALDPAGLPLAPEG
CCEEEECCCCCCCCCEECCCCCEEHHHHHHHHHCHHHHHHHHHHHEEEECCCCCCCCCCC
VRLGSCVARPGNFIAVGLNYADHAAETNNPIPEEPVLFNKAPNCVVGPNDDVMVPKNSQK
CEECCEECCCCCEEEEECCCHHHHHCCCCCCCCCCEEECCCCCEEECCCCCEEECCCCCC
LDWEVELVIVIGDRARYVDEKDALKHVAGYTICNDVSERHFQIERAGQWTKGKGSETFGP
CCEEEEEEEEECCCCHHCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCC
LGPWMVTTDELTDTSSLGMWLEVNGERVQNGSTKTMIFNVAYLVSYISQFMVLDPGDIIT
CCCEEEEECCCCCCCCCEEEEEECCCEECCCCCEEEEHHHHHHHHHHHHHEEECCCCEEE
TGTPPGVGLGFKPPRYLKAGDVVRLGIDGLGEQQQTIVPFKL
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA