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The map label for this gene is ifcA [H]

Identifier: 158423729

GI number: 158423729

Start: 2421402

End: 2422799

Strand: Reverse

Name: ifcA [H]

Synonym: AZC_2105

Alternate gene names: 158423729

Gene position: 2422799-2421402 (Counterclockwise)

Preceding gene: 158423743

Following gene: 158423721

Centisome position: 45.12

GC content: 70.6

Gene sequence:

>1398_bases
GTGAGCCCCATTGTCCGCCAGTCCGGAAAAACCTTCGGCTTCCATGTGCCCGTGGTCATCATCGGCGCCGGGGCAGCGGG
CCTCGTGGCGGCACTGGCGGCGCAAGAGGCCGGGGCCGAGGTGCTGGTACTGGAGCGCGATCCGGTGCCGCGCGGTTCGA
CGGCGCTCTCCGCCGGTCTCATCCCTGCCGCCGGCACACGCTGGCAGACGGAGGCGGGCATCGCCGATTCGGCCGCGCAG
TTCGCCGCCGACATCATGGCCAAGGCCCATGGCGAGCCGGACGCTACCCTCGTGGCACGCATCGCGGCGGAAGCCGGCCC
GGCCGTGGAGTGGCTGGCCGACACCCACGGCCTGCCCTTTTCGGTGATCTCCGACTTCAGCTACCCCGGCCACAGCGCCC
GGCGGATGCACGGCCTGCCGTCGCGCTCCGGCGAGGAACTGGTGGATGCCCTGCGCGGCGCCGCCGAGGCTCGCGGCATC
GAGATCCTCTGCGACGCCCGCGTCACGCAGCTTCATGCCGACGAAAACGACCGCCTGCTGGGCGTCACGCTGGAGCGGCC
GGACGGCTCGACGGAGGAGGTTGCCCTCTGCCAGCTCGTGCTCGCCTGCAACGGCTATGGCGGCAATGCCGATCTGGTGC
GCGCCCACATCCCGACGCTCGCCGACGCGCTTTATTTCGGCCACACGGGTAATCAGGGCGATGCCCTGCTGTGGGGCGAG
GCGCTGGGCGCGGCCACCCGGCATCTGTCCGGCCATCAGGGCCACGGCTCGGTGGCGTATCCCGCCGGCATCCTCATCAC
CTGGGCCACCATCACGGAAGGCGGCGTGCAGGTAAATGCGGAAGGGCGGCGCTTCAGCAATGAGATGCATGGCTATTCCG
AGCAGGCCGCCGAGGTGTTGCGACAGCCGAACCGGATGGCCTGGACAATCTTCGACACCCGCATCGCCGGCATCGCCCGG
CAATTCGAGGATTTCCGGCAGGCCGAGGCCATAGGCGCAATCGTTACAGCCGACACGCCGCAGGCGCTCGCCGCGCGCAC
CGGTCTGCCGGCGGACGCGCTCATCTCGACCCTGTCCGACGTGGAGCGGCTGAAGTTGGACGGCGCCACCGATACCTTCG
GCCGCGCCTTCCGTGCCGACCAGCAGCTCTCGGCGCCATTCCATGCGGTGCGTGTGACCGGCGCGCTGTTCCACACCCAG
GGCGGCCTCGTGGTGGACGAGCACGCGCGTGTGCTGCGGCCCGACGGCACATCCCTGCCCAACCTCTACGCCTCGGGCGG
GGCAGCATGCGGCGTCTCGGGTTCGCAGGCGTCCGGCTATCTGTCAGGGAATGGCCTGCTCACCGCCGTGGTGCTGGGAC
GCCTTGCCGGATCCGCAGCGGGCGCCGCCGTCGCCTGA

Upstream 100 bases:

>100_bases
AAGGGTAGGCCCGTTCCGGCGCGAGAGGCAATACTTGTTTTATATCTAGTACAGCTTACTGTCCTGCACCGAGACATAAC
CTGAGACGCGCGAGGCCGCC

Downstream 100 bases:

>100_bases
CGGCTCCGCCGGGCCAGGACGACCTCAGGGAACACGCTTCTTCTCGAGCTTGCGGGCGAGCGTGCGGCGATGCATGCCGA
GACGGCGGGCGGTCTCGGAA

Product: fumarate reductase

Products: NA

Alternate protein names: Fe(3+)-induced flavocytochrome C3; Ifc3; Iron(III)-induced flavocytochrome C3 [H]

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MSPIVRQSGKTFGFHVPVVIIGAGAAGLVAALAAQEAGAEVLVLERDPVPRGSTALSAGLIPAAGTRWQTEAGIADSAAQ
FAADIMAKAHGEPDATLVARIAAEAGPAVEWLADTHGLPFSVISDFSYPGHSARRMHGLPSRSGEELVDALRGAAEARGI
EILCDARVTQLHADENDRLLGVTLERPDGSTEEVALCQLVLACNGYGGNADLVRAHIPTLADALYFGHTGNQGDALLWGE
ALGAATRHLSGHQGHGSVAYPAGILITWATITEGGVQVNAEGRRFSNEMHGYSEQAAEVLRQPNRMAWTIFDTRIAGIAR
QFEDFRQAEAIGAIVTADTPQALAARTGLPADALISTLSDVERLKLDGATDTFGRAFRADQQLSAPFHAVRVTGALFHTQ
GGLVVDEHARVLRPDGTSLPNLYASGGAACGVSGSQASGYLSGNGLLTAVVLGRLAGSAAGAAVA

Sequences:

>Translated_465_residues
MSPIVRQSGKTFGFHVPVVIIGAGAAGLVAALAAQEAGAEVLVLERDPVPRGSTALSAGLIPAAGTRWQTEAGIADSAAQ
FAADIMAKAHGEPDATLVARIAAEAGPAVEWLADTHGLPFSVISDFSYPGHSARRMHGLPSRSGEELVDALRGAAEARGI
EILCDARVTQLHADENDRLLGVTLERPDGSTEEVALCQLVLACNGYGGNADLVRAHIPTLADALYFGHTGNQGDALLWGE
ALGAATRHLSGHQGHGSVAYPAGILITWATITEGGVQVNAEGRRFSNEMHGYSEQAAEVLRQPNRMAWTIFDTRIAGIAR
QFEDFRQAEAIGAIVTADTPQALAARTGLPADALISTLSDVERLKLDGATDTFGRAFRADQQLSAPFHAVRVTGALFHTQ
GGLVVDEHARVLRPDGTSLPNLYASGGAACGVSGSQASGYLSGNGLLTAVVLGRLAGSAAGAAVA
>Mature_464_residues
SPIVRQSGKTFGFHVPVVIIGAGAAGLVAALAAQEAGAEVLVLERDPVPRGSTALSAGLIPAAGTRWQTEAGIADSAAQF
AADIMAKAHGEPDATLVARIAAEAGPAVEWLADTHGLPFSVISDFSYPGHSARRMHGLPSRSGEELVDALRGAAEARGIE
ILCDARVTQLHADENDRLLGVTLERPDGSTEEVALCQLVLACNGYGGNADLVRAHIPTLADALYFGHTGNQGDALLWGEA
LGAATRHLSGHQGHGSVAYPAGILITWATITEGGVQVNAEGRRFSNEMHGYSEQAAEVLRQPNRMAWTIFDTRIAGIARQ
FEDFRQAEAIGAIVTADTPQALAARTGLPADALISTLSDVERLKLDGATDTFGRAFRADQQLSAPFHAVRVTGALFHTQG
GLVVDEHARVLRPDGTSLPNLYASGGAACGVSGSQASGYLSGNGLLTAVVLGRLAGSAAGAAVA

Specific function: Catalyzes unidirectional fumarate reduction using artificial electron donors such as methyl viologen. The physiological reductant is unknown [H]

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI71986328, Length=480, Percent_Identity=25, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6320788, Length=480, Percent_Identity=25.625, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322511, Length=478, Percent_Identity=23.2217573221757, Blast_Score=94, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR010960
- InterPro:   IPR011031 [H]

Pfam domain/function: PF00890 FAD_binding_2 [H]

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 48046; Mature: 47915

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPIVRQSGKTFGFHVPVVIIGAGAAGLVAALAAQEAGAEVLVLERDPVPRGSTALSAGL
CCCCHHCCCCEEEEECCEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHCCC
IPAAGTRWQTEAGIADSAAQFAADIMAKAHGEPDATLVARIAAEAGPAVEWLADTHGLPF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCH
SVISDFSYPGHSARRMHGLPSRSGEELVDALRGAAEARGIEILCDARVTQLHADENDRLL
HHHHCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEEECCEEEEEECCCCCCEE
GVTLERPDGSTEEVALCQLVLACNGYGGNADLVRAHIPTLADALYFGHTGNQGDALLWGE
EEEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHCCCCCCCCCEEEEHH
ALGAATRHLSGHQGHGSVAYPAGILITWATITEGGVQVNAEGRRFSNEMHGYSEQAAEVL
HHHHHHHHCCCCCCCCCEECCCCEEEEEEEECCCCEEECCCCHHHHHHHCCHHHHHHHHH
RQPNRMAWTIFDTRIAGIARQFEDFRQAEAIGAIVTADTPQALAARTGLPADALISTLSD
HCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHCCCCHHHHHHHHHH
VERLKLDGATDTFGRAFRADQQLSAPFHAVRVTGALFHTQGGLVVDEHARVLRPDGTSLP
HHHHCCCCCCCHHHHHHCCCCHHCCCHHHEEEEEEEEECCCCEEEECCCEEECCCCCCCC
NLYASGGAACGVSGSQASGYLSGNGLLTAVVLGRLAGSAAGAAVA
CHHCCCCCEECCCCCCCCCEECCCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SPIVRQSGKTFGFHVPVVIIGAGAAGLVAALAAQEAGAEVLVLERDPVPRGSTALSAGL
CCCHHCCCCEEEEECCEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHCCC
IPAAGTRWQTEAGIADSAAQFAADIMAKAHGEPDATLVARIAAEAGPAVEWLADTHGLPF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCH
SVISDFSYPGHSARRMHGLPSRSGEELVDALRGAAEARGIEILCDARVTQLHADENDRLL
HHHHCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEEECCEEEEEECCCCCCEE
GVTLERPDGSTEEVALCQLVLACNGYGGNADLVRAHIPTLADALYFGHTGNQGDALLWGE
EEEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHCCCCCCCCCEEEEHH
ALGAATRHLSGHQGHGSVAYPAGILITWATITEGGVQVNAEGRRFSNEMHGYSEQAAEVL
HHHHHHHHCCCCCCCCCEECCCCEEEEEEEECCCCEEECCCCHHHHHHHCCHHHHHHHHH
RQPNRMAWTIFDTRIAGIARQFEDFRQAEAIGAIVTADTPQALAARTGLPADALISTLSD
HCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHCCCCHHHHHHHHHH
VERLKLDGATDTFGRAFRADQQLSAPFHAVRVTGALFHTQGGLVVDEHARVLRPDGTSLP
HHHHCCCCCCCHHHHHHCCCCHHCCCHHHEEEEEEEEECCCCEEEECCCEEECCCCCCCC
NLYASGGAACGVSGSQASGYLSGNGLLTAVVLGRLAGSAAGAAVA
CHHCCCCCEECCCCCCCCCEECCCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10455032; 10581549 [H]