Click here to switch to the map view.

The map label for this gene is ygjG [C]

Identifier: 158423655

GI number: 158423655

Start: 2342690

End: 2344063

Strand: Reverse

Name: ygjG [C]

Synonym: AZC_2031

Alternate gene names: 158423655

Gene position: 2344063-2342690 (Counterclockwise)

Preceding gene: 158423656

Following gene: 158423654

Centisome position: 43.65

GC content: 68.2

Gene sequence:

>1374_bases
ATGACCAGCAATTCCCTCGTTGAACTCGACCGCGCCCATCTGGTGCATCCGGTCGCCTCGTATCGCGGCCACGAGCGGGC
GGGCGTCCGGGTGCTCAAATCCGCCAAGGGCGCCATCGTCACCGATGCCACGGGCCACAGCATGATCGACGGCTTCGCCG
GACTGTGGTGCGTGAATGCGGGCTACGGCGTCGAGAGCATTGTCGAGGCGGCGGCCAAGCAGATGCGCGAACTGCCCTAT
GCCACCGGCTATTTCAGCCTCGGATCGGAAAGCGCCATTCGCCTCGCGGCGGAACTGGCGGACCGCGCGCCGGGCGATCT
CAACCACGTCTATTTCACGCTCGGTGGTTCGGACGCCGTGGATTCCACCGTCCGCTTCGTCCGCTATTATCAGCACGCGC
GCGGCACGCCGCAGAAGGACCAGTTCATCTCGCTGGCGAGCGGCTATCATGGCTCCTCGACCGTAGGCGCCGGCCTCACC
GCTCTGCCACTGTTCCACGCCGGCTTCGGCCTGCCCTTCGACTGGCAGCATAAAATTCCGTCCCACTATGCCTATCGTAA
TCCGGTAGGGAGCGACCCCGCAGCGATCATCGCCGCCTCGGTGGCCGCGCTTCGAGCGAAGGTGGAGGAGATCGGGCCGG
ATCGCGTCGCCGCCTTCTATGCCGAGCCCATCCAGGGGTCCGGCGGCGTTCTCGTGCCGCCGGACGGCTGGATGAAGGCC
ATGCGGGAGGTCTGCCGCGAACTCGACATCCTCTTCGTGGCCGACGAGGTCATCACCGGCTTCGGGCGCACCGGCCCCCT
TTTCGCCTGCACGGACGAGGGGATCGTTCCCGACCTCATGACCACCGCCAAGGGGCTCACCTCGGGTTATGTGCCCATGG
GCGCGGTGTTCCTGTCCGATCACGTCTACAACACCATCGCCGACGGCGCCGGCGAGTCAGCCGTCGGCCACGGCTACACC
TATTCCGCCCATCCGGTCAGCGCGGCGGTCGGCCTCGAGGTGCTGCGGCTCTACGAGGCGGGACTGCTGGAGAACGGCCG
CAGGGCCGGCGCGCGACTGATGGCGGGGCTCCGGAGCCTCTCCGACCATCCGCTGGTGGGCGACGTGCGCGGGCGCGGCA
TGCTGGCCGCCATCGAGCTCGTCACCGACAAGGCCCGCAAGACACCGCTGCCGGCGGCCGCCGACCCCTCCCACCGCATC
TTCGACCGCGCGTGGGACAATGGCCTTGTCATCCGTGCCTTCGCCACCGGCATCCTCGGCTATGCGCCGCCGCTCTGCTG
CACCGACGCCGACATCGACGGCATCATCGAGCGCACCCGCATGACGCTGGACCAGACCCTGGAAGACCCGGACGTCCGCG
CCGCCATGGCCTGA

Upstream 100 bases:

>100_bases
CGGCACGCCGATGATCCGCAATGCCCGCTCGGCGGCGCCCGTCGATGGCGTCCGCACGTTTGCCCTCGCCAGCCAGGCCC
TTGGTTGAAGGAGAAGCCTG

Downstream 100 bases:

>100_bases
GCGGGAACCGACATTCCGGCGGGCGGCTGATTTCAGAAGATTCTGCCGCCCGCCGCCCGCGTTTCAGCCGATCCCGCGCT
GCACACTTGGCAACACTGAA

Product: hypothetical protein

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MTSNSLVELDRAHLVHPVASYRGHERAGVRVLKSAKGAIVTDATGHSMIDGFAGLWCVNAGYGVESIVEAAAKQMRELPY
ATGYFSLGSESAIRLAAELADRAPGDLNHVYFTLGGSDAVDSTVRFVRYYQHARGTPQKDQFISLASGYHGSSTVGAGLT
ALPLFHAGFGLPFDWQHKIPSHYAYRNPVGSDPAAIIAASVAALRAKVEEIGPDRVAAFYAEPIQGSGGVLVPPDGWMKA
MREVCRELDILFVADEVITGFGRTGPLFACTDEGIVPDLMTTAKGLTSGYVPMGAVFLSDHVYNTIADGAGESAVGHGYT
YSAHPVSAAVGLEVLRLYEAGLLENGRRAGARLMAGLRSLSDHPLVGDVRGRGMLAAIELVTDKARKTPLPAAADPSHRI
FDRAWDNGLVIRAFATGILGYAPPLCCTDADIDGIIERTRMTLDQTLEDPDVRAAMA

Sequences:

>Translated_457_residues
MTSNSLVELDRAHLVHPVASYRGHERAGVRVLKSAKGAIVTDATGHSMIDGFAGLWCVNAGYGVESIVEAAAKQMRELPY
ATGYFSLGSESAIRLAAELADRAPGDLNHVYFTLGGSDAVDSTVRFVRYYQHARGTPQKDQFISLASGYHGSSTVGAGLT
ALPLFHAGFGLPFDWQHKIPSHYAYRNPVGSDPAAIIAASVAALRAKVEEIGPDRVAAFYAEPIQGSGGVLVPPDGWMKA
MREVCRELDILFVADEVITGFGRTGPLFACTDEGIVPDLMTTAKGLTSGYVPMGAVFLSDHVYNTIADGAGESAVGHGYT
YSAHPVSAAVGLEVLRLYEAGLLENGRRAGARLMAGLRSLSDHPLVGDVRGRGMLAAIELVTDKARKTPLPAAADPSHRI
FDRAWDNGLVIRAFATGILGYAPPLCCTDADIDGIIERTRMTLDQTLEDPDVRAAMA
>Mature_456_residues
TSNSLVELDRAHLVHPVASYRGHERAGVRVLKSAKGAIVTDATGHSMIDGFAGLWCVNAGYGVESIVEAAAKQMRELPYA
TGYFSLGSESAIRLAAELADRAPGDLNHVYFTLGGSDAVDSTVRFVRYYQHARGTPQKDQFISLASGYHGSSTVGAGLTA
LPLFHAGFGLPFDWQHKIPSHYAYRNPVGSDPAAIIAASVAALRAKVEEIGPDRVAAFYAEPIQGSGGVLVPPDGWMKAM
REVCRELDILFVADEVITGFGRTGPLFACTDEGIVPDLMTTAKGLTSGYVPMGAVFLSDHVYNTIADGAGESAVGHGYTY
SAHPVSAAVGLEVLRLYEAGLLENGRRAGARLMAGLRSLSDHPLVGDVRGRGMLAAIELVTDKARKTPLPAAADPSHRIF
DRAWDNGLVIRAFATGILGYAPPLCCTDADIDGIIERTRMTLDQTLEDPDVRAAMA

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=411, Percent_Identity=29.683698296837, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI226442705, Length=408, Percent_Identity=30.1470588235294, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI226442709, Length=390, Percent_Identity=30, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI24119277, Length=431, Percent_Identity=28.538283062645, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI13994255, Length=469, Percent_Identity=27.0788912579957, Blast_Score=142, Evalue=9e-34,
Organism=Homo sapiens, GI4557809, Length=417, Percent_Identity=28.2973621103118, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI284507298, Length=230, Percent_Identity=34.3478260869565, Blast_Score=118, Evalue=1e-26,
Organism=Escherichia coli, GI145693181, Length=351, Percent_Identity=31.9088319088319, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1789016, Length=420, Percent_Identity=30.4761904761905, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI1788044, Length=407, Percent_Identity=27.2727272727273, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1789759, Length=407, Percent_Identity=26.2899262899263, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787560, Length=414, Percent_Identity=30.6763285024155, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1786991, Length=390, Percent_Identity=28.7179487179487, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI1786349, Length=429, Percent_Identity=25.1748251748252, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI32564660, Length=447, Percent_Identity=29.3064876957494, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI25144271, Length=411, Percent_Identity=27.007299270073, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI71992977, Length=427, Percent_Identity=29.2740046838407, Blast_Score=133, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI25144274, Length=231, Percent_Identity=32.9004329004329, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17541228, Length=484, Percent_Identity=23.3471074380165, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6324386, Length=364, Percent_Identity=26.6483516483516, Blast_Score=113, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6323470, Length=472, Percent_Identity=25.2118644067797, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6324432, Length=430, Percent_Identity=23.0232558139535, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6321456, Length=382, Percent_Identity=23.8219895287958, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI28574759, Length=475, Percent_Identity=29.8947368421053, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI161085790, Length=461, Percent_Identity=30.3687635574837, Blast_Score=151, Evalue=7e-37,
Organism=Drosophila melanogaster, GI21357415, Length=265, Percent_Identity=33.5849056603774, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21356575, Length=429, Percent_Identity=26.8065268065268, Blast_Score=122, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 48555; Mature: 48423

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSNSLVELDRAHLVHPVASYRGHERAGVRVLKSAKGAIVTDATGHSMIDGFAGLWCVNA
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCCHHHHHHHHHHEEECC
GYGVESIVEAAAKQMRELPYATGYFSLGSESAIRLAAELADRAPGDLNHVYFTLGGSDAV
CCCHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCHHH
DSTVRFVRYYQHARGTPQKDQFISLASGYHGSSTVGAGLTALPLFHAGFGLPFDWQHKIP
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
SHYAYRNPVGSDPAAIIAASVAALRAKVEEIGPDRVAAFYAEPIQGSGGVLVPPDGWMKA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHEEHHHHCCCCCCCCEEECCHHHHHH
MREVCRELDILFVADEVITGFGRTGPLFACTDEGIVPDLMTTAKGLTSGYVPMGAVFLSD
HHHHHHHCCEEEEEHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHH
HVYNTIADGAGESAVGHGYTYSAHPVSAAVGLEVLRLYEAGLLENGRRAGARLMAGLRSL
HHHHHHHCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
SDHPLVGDVRGRGMLAAIELVTDKARKTPLPAAADPSHRIFDRAWDNGLVIRAFATGILG
CCCCCEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEHHHHHHHHH
YAPPLCCTDADIDGIIERTRMTLDQTLEDPDVRAAMA
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHCCC
>Mature Secondary Structure 
TSNSLVELDRAHLVHPVASYRGHERAGVRVLKSAKGAIVTDATGHSMIDGFAGLWCVNA
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCCHHHHHHHHHHEEECC
GYGVESIVEAAAKQMRELPYATGYFSLGSESAIRLAAELADRAPGDLNHVYFTLGGSDAV
CCCHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCHHH
DSTVRFVRYYQHARGTPQKDQFISLASGYHGSSTVGAGLTALPLFHAGFGLPFDWQHKIP
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
SHYAYRNPVGSDPAAIIAASVAALRAKVEEIGPDRVAAFYAEPIQGSGGVLVPPDGWMKA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHEEHHHHCCCCCCCCEEECCHHHHHH
MREVCRELDILFVADEVITGFGRTGPLFACTDEGIVPDLMTTAKGLTSGYVPMGAVFLSD
HHHHHHHCCEEEEEHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHH
HVYNTIADGAGESAVGHGYTYSAHPVSAAVGLEVLRLYEAGLLENGRRAGARLMAGLRSL
HHHHHHHCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
SDHPLVGDVRGRGMLAAIELVTDKARKTPLPAAADPSHRIFDRAWDNGLVIRAFATGILG
CCCCCEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEHHHHHHHHH
YAPPLCCTDADIDGIIERTRMTLDQTLEDPDVRAAMA
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]