Click here to switch to the map view.

The map label for this gene is 158423641

Identifier: 158423641

GI number: 158423641

Start: 2326466

End: 2327401

Strand: Reverse

Name: 158423641

Synonym: AZC_2017

Alternate gene names: NA

Gene position: 2327401-2326466 (Counterclockwise)

Preceding gene: 158423643

Following gene: 158423640

Centisome position: 43.34

GC content: 64.53

Gene sequence:

>936_bases
GTGTCCCGTATCCTGACCGTCGCTGCCGCCCAGTTGGGTCCCATCCAGCGTGCGGATACGCGCGCTTCCGTCGTGCGGCG
CCTCTGCGACCTGCTGCGGCAGGCCGCCGGGCATGGCTGCGATCTCGTGGTCTTCCCGGAACTCGCGCTCACCACCTTCT
TTCCGCGCTGGTATACGGAAGACCAGACTGAGATCGACGCCTTCTTCGAAACCGCACTTCCTTCGGCCGAGACGGCTCCT
CTCTTTGCGCTCGCCGGTGCGCTGAAAGTGGGCTTCTGCCTCGGCTACGCGGAACTGGTGGAGGAAGACGGCCGGCTGCG
ACGCTTCAACACCTCGGTCATCGTCGACAAGTCGGGCGAGATCGTTCTCAAATATCGAAAGATTCATCTGCCCGGCCATG
CCGAGCACGAACCTTGGCGCGCCTTCCAGCATCTGGAGAAGCGCTATTTCGAGGTTGGGAACCTGAATTGGCCGGTCCGC
CGCATCATGGGCGGCGTGCTCGGCATGGCCATCTGCAACGACCGGCGCTGGCCCGAGACCTATCGCGTGATGGGCCTCAA
GGGCGTTGAGATGGTGCTCATCGGCTACAACACGCCGCGCCACAATCCACCCGCCCCCGACCACGACCGGCTCTCCGAGT
TTCACAACCAGCTCTCCATGCAGGCCGGCGCCTACCAGAACGGCACGTGGGTGGTGGGCGCGGCCAAATGCGGCGTGGAG
GAAGGCTGCGAGATGATCGGCGCCTCCTCGATCATTGCCCCGTCCGGCCAGATCGTGGCGCAGGCACTGACGCAGGACGA
TGAACTGGTGCTCGCCCGCTGCGACCTCGACATGTGCGCCTCCTACAAGGAGACCACCTTCAATTTCGCCAAGCACCGGC
AGCCGGAGGCCTATCGGCTGATCGTCGAACAGACGGGCGCCATCGCGCCCGAATGA

Upstream 100 bases:

>100_bases
GTGGCACGCCTCTTGCGAAGCGTGAGCAGGATGGCTTCCTCGAGAAGCCGAAGACGCGGGGAGTTCCTTTGCACGTCGCT
CACTTGCCTAAGGCTGGCCC

Downstream 100 bases:

>100_bases
GCGTCCGCTGCCCTTTGAATGTTCCGTCTGGAGACTGGTAGATGGCTTTTGATCTGATCCTGCGCGGTGGTCACGTGATC
GACCCCTCGCAGAATATCGA

Product: N-carbamyl-D-amino acid amidohydrolase

Products: NA

Alternate protein names: D-N-alpha-carbamilase [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSRILTVAAAQLGPIQRADTRASVVRRLCDLLRQAAGHGCDLVVFPELALTTFFPRWYTEDQTEIDAFFETALPSAETAP
LFALAGALKVGFCLGYAELVEEDGRLRRFNTSVIVDKSGEIVLKYRKIHLPGHAEHEPWRAFQHLEKRYFEVGNLNWPVR
RIMGGVLGMAICNDRRWPETYRVMGLKGVEMVLIGYNTPRHNPPAPDHDRLSEFHNQLSMQAGAYQNGTWVVGAAKCGVE
EGCEMIGASSIIAPSGQIVAQALTQDDELVLARCDLDMCASYKETTFNFAKHRQPEAYRLIVEQTGAIAPE

Sequences:

>Translated_311_residues
MSRILTVAAAQLGPIQRADTRASVVRRLCDLLRQAAGHGCDLVVFPELALTTFFPRWYTEDQTEIDAFFETALPSAETAP
LFALAGALKVGFCLGYAELVEEDGRLRRFNTSVIVDKSGEIVLKYRKIHLPGHAEHEPWRAFQHLEKRYFEVGNLNWPVR
RIMGGVLGMAICNDRRWPETYRVMGLKGVEMVLIGYNTPRHNPPAPDHDRLSEFHNQLSMQAGAYQNGTWVVGAAKCGVE
EGCEMIGASSIIAPSGQIVAQALTQDDELVLARCDLDMCASYKETTFNFAKHRQPEAYRLIVEQTGAIAPE
>Mature_310_residues
SRILTVAAAQLGPIQRADTRASVVRRLCDLLRQAAGHGCDLVVFPELALTTFFPRWYTEDQTEIDAFFETALPSAETAPL
FALAGALKVGFCLGYAELVEEDGRLRRFNTSVIVDKSGEIVLKYRKIHLPGHAEHEPWRAFQHLEKRYFEVGNLNWPVRR
IMGGVLGMAICNDRRWPETYRVMGLKGVEMVLIGYNTPRHNPPAPDHDRLSEFHNQLSMQAGAYQNGTWVVGAAKCGVEE
GCEMIGASSIIAPSGQIVAQALTQDDELVLARCDLDMCASYKETTFNFAKHRQPEAYRLIVEQTGAIAPE

Specific function: The enzyme catalyzes the hydrolysis of N-carbamoyl-D- amino acids to the corresponding which are useful intermediates in the preparation of beta-lactam antibiotics. Industrial production of beta-lactam antibiotics is now being developed using this enzyme

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI21358471, Length=305, Percent_Identity=25.2459016393443, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: =3.5.1.77 [H]

Molecular weight: Translated: 34664; Mature: 34533

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRILTVAAAQLGPIQRADTRASVVRRLCDLLRQAAGHGCDLVVFPELALTTFFPRWYTE
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHCCCCCCC
DQTEIDAFFETALPSAETAPLFALAGALKVGFCLGYAELVEEDGRLRRFNTSVIVDKSGE
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEECCCC
IVLKYRKIHLPGHAEHEPWRAFQHLEKRYFEVGNLNWPVRRIMGGVLGMAICNDRRWPET
EEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHH
YRVMGLKGVEMVLIGYNTPRHNPPAPDHDRLSEFHNQLSMQAGAYQNGTWVVGAAKCGVE
HHEECCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEHHCCHH
EGCEMIGASSIIAPSGQIVAQALTQDDELVLARCDLDMCASYKETTFNFAKHRQPEAYRL
HHHHHHCCCCEECCCHHHHHHHHCCCCCEEEEECCHHHHCCHHHHHHHHHHCCCCHHHHH
IVEQTGAIAPE
HHHHCCCCCCC
>Mature Secondary Structure 
SRILTVAAAQLGPIQRADTRASVVRRLCDLLRQAAGHGCDLVVFPELALTTFFPRWYTE
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHCCCCCCC
DQTEIDAFFETALPSAETAPLFALAGALKVGFCLGYAELVEEDGRLRRFNTSVIVDKSGE
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEECCCC
IVLKYRKIHLPGHAEHEPWRAFQHLEKRYFEVGNLNWPVRRIMGGVLGMAICNDRRWPET
EEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHH
YRVMGLKGVEMVLIGYNTPRHNPPAPDHDRLSEFHNQLSMQAGAYQNGTWVVGAAKCGVE
HHEECCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEHHCCHH
EGCEMIGASSIIAPSGQIVAQALTQDDELVLARCDLDMCASYKETTFNFAKHRQPEAYRL
HHHHHHCCCCEECCCHHHHHHHHCCCCCEEEEECCHHHHCCHHHHHHHHHHCCCCHHHHH
IVEQTGAIAPE
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9648217; 10903946 [H]