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The map label for this gene is gntR [H]

Identifier: 158423598

GI number: 158423598

Start: 2276954

End: 2277688

Strand: Reverse

Name: gntR [H]

Synonym: AZC_1974

Alternate gene names: 158423598

Gene position: 2277688-2276954 (Counterclockwise)

Preceding gene: 158423606

Following gene: 158423596

Centisome position: 42.42

GC content: 66.94

Gene sequence:

>735_bases
ATGGCCGGATCAGCTTCCCAACCGTTACCTCAGCCCCCTTCCCCGCTGGTGCAGCGGGTGCATCACCAATTGCGGGCGCG
CATCACGTCCGGCGAATATCCGCCGCACTCACGGCTGCCGGGGGAGCACGACCTCTCGGCCCTGTTCGGCGTGTCGCGGC
CTGTGGTGCGCGAGGCCCTGCGCCGCCTGCGGGAAGACGGGCTGGTCTTCTCCCGGCAGGGCGCCGGCACATTCGTGCGG
GGTCCGGAACCGGAGAGCGGCAAGGCCCTCGCCTATGCGCCCGTCGGAACCATCGCGGATGTGCAGCGCTGCTACGAATT
CCGCCTCGAAGTCGAACCGGCGAACGCCTTCTATGCGGCACAGCGCAACAATCGCGCAGCCCTCGACACCATCGAGCGTG
CGCTCGATCTGCTGCGGGACACCACCTATGCCCACCGCCATCGGGAGGATGCGGACTACGCCTTCCACATCTCCATCGCG
GAGGCGTCGAACAATTATTTCTTCCTCTCCTCCATGCAGGCGCTCAAGGAGCACATCACGGTGGGGATGAAACTGCACGG
CCTCTCCCTGCTCGGCCCGTCCGGCGATCTCGCCGCCGTCCTCGAGGAGCACGCCTCCATCTTCGCCGCCATTCGAGACC
ACAAGGCGGAAGAGGCGCGCGACGCCATGAGGCGGCACATCCAGGGCTCCTACGACCGCCTGTTCGAGGGCAAGGTGCTC
GACCTCGCCCTGTGA

Upstream 100 bases:

>100_bases
TGTTGTAATAACCCAGACACAACACGAAGCCGCCAAACCGAGGTTGAGCAGGAAGACAAGGCACCTTGACGAACATGTCA
TGAGTTGTAATGGATAGTTC

Downstream 100 bases:

>100_bases
CGGCCCCTGGACAGCCGCGCAGGACTTACAACATGCTGACAGATGGCGGGGGTGACCAACAAAACCCCGCCTCGCCTTCC
AGACGTGCCGCGAGCGCAAT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MAGSASQPLPQPPSPLVQRVHHQLRARITSGEYPPHSRLPGEHDLSALFGVSRPVVREALRRLREDGLVFSRQGAGTFVR
GPEPESGKALAYAPVGTIADVQRCYEFRLEVEPANAFYAAQRNNRAALDTIERALDLLRDTTYAHRHREDADYAFHISIA
EASNNYFFLSSMQALKEHITVGMKLHGLSLLGPSGDLAAVLEEHASIFAAIRDHKAEEARDAMRRHIQGSYDRLFEGKVL
DLAL

Sequences:

>Translated_244_residues
MAGSASQPLPQPPSPLVQRVHHQLRARITSGEYPPHSRLPGEHDLSALFGVSRPVVREALRRLREDGLVFSRQGAGTFVR
GPEPESGKALAYAPVGTIADVQRCYEFRLEVEPANAFYAAQRNNRAALDTIERALDLLRDTTYAHRHREDADYAFHISIA
EASNNYFFLSSMQALKEHITVGMKLHGLSLLGPSGDLAAVLEEHASIFAAIRDHKAEEARDAMRRHIQGSYDRLFEGKVL
DLAL
>Mature_243_residues
AGSASQPLPQPPSPLVQRVHHQLRARITSGEYPPHSRLPGEHDLSALFGVSRPVVREALRRLREDGLVFSRQGAGTFVRG
PEPESGKALAYAPVGTIADVQRCYEFRLEVEPANAFYAAQRNNRAALDTIERALDLLRDTTYAHRHREDADYAFHISIAE
ASNNYFFLSSMQALKEHITVGMKLHGLSLLGPSGDLAAVLEEHASIFAAIRDHKAEEARDAMRRHIQGSYDRLFEGKVLD
LAL

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=224, Percent_Identity=29.4642857142857, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790780, Length=233, Percent_Identity=31.3304721030043, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786303, Length=213, Percent_Identity=28.6384976525822, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27100; Mature: 26969

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGSASQPLPQPPSPLVQRVHHQLRARITSGEYPPHSRLPGEHDLSALFGVSRPVVREAL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHH
RRLREDGLVFSRQGAGTFVRGPEPESGKALAYAPVGTIADVQRCYEFRLEVEPANAFYAA
HHHHHCCCEEEECCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHEEECCCCCEEEC
QRNNRAALDTIERALDLLRDTTYAHRHREDADYAFHISIAEASNNYFFLSSMQALKEHIT
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCEEEHHHHHHHHHHHH
VGMKLHGLSLLGPSGDLAAVLEEHASIFAAIRDHKAEEARDAMRRHIQGSYDRLFEGKVL
HCEEEECEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHCCCEE
DLAL
EECC
>Mature Secondary Structure 
AGSASQPLPQPPSPLVQRVHHQLRARITSGEYPPHSRLPGEHDLSALFGVSRPVVREAL
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHH
RRLREDGLVFSRQGAGTFVRGPEPESGKALAYAPVGTIADVQRCYEFRLEVEPANAFYAA
HHHHHCCCEEEECCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHEEECCCCCEEEC
QRNNRAALDTIERALDLLRDTTYAHRHREDADYAFHISIAEASNNYFFLSSMQALKEHIT
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCEEEHHHHHHHHHHHH
VGMKLHGLSLLGPSGDLAAVLEEHASIFAAIRDHKAEEARDAMRRHIQGSYDRLFEGKVL
HCEEEECEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHCCCEE
DLAL
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]