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The map label for this gene is lysR [H]

Identifier: 158423588

GI number: 158423588

Start: 2266713

End: 2267630

Strand: Reverse

Name: lysR [H]

Synonym: AZC_1964

Alternate gene names: 158423588

Gene position: 2267630-2266713 (Counterclockwise)

Preceding gene: 158423589

Following gene: 158423587

Centisome position: 42.23

GC content: 67.65

Gene sequence:

>918_bases
ATGCGCGAGGGCGACGAACCACAGGTCTCCTTGTCCCTGCTGGAAATCTTCGGCGCGATGATGCGTTGCCAGACGACGGT
GGAGGCAGCCGAGCAACTGGGCATCTCCCAGCCGGCGGTCTCCAACGGCCTGCGCCAGCTGGAGCGGGAACTGGGCATCA
CCTTGTTCGAGCGGGCGCACCGGCGGCTGGAGCCCACCGCCGAGGCGCTCTCGCTCTACGAGGAAATCAGGCCCCTGTTC
GGCGTCCTGCGCAGCTTTTCGCTAAGGGCACGGGACATCCGGCAGGGCAAGTCCGGACGCATCCGCATCGTCGCCACCCC
GCCCATCGGCCACACCGCCGCGCCGAGGGCGCTGCGGGCCTTGCTGGAGGAGCGGCCGGAGGTCTCCGTTTCCTATGACG
TGCGCCGCCTCTCCGACATTCTCGCCGCGCTCAAGGAAGGTTCGGCCGATGTGGGCATTGCGCTCGCCATCGACCAGGAC
CTCGACGTGAATGTGGAGGTGCTCCACCGCACCCACATGGTGGCGCTTGTTCCTGTAGGCTCGGCTCTGGCGAACCGGTC
CGAAGTCACCGCCAGCGAAGTGGCGGGGCATCGCTTCGTGGGGCTGGAAGCGGCATCGCGCCTCGGCCAGATCCTGCGCT
CGGCCTTCGACCGCGACCACGCCACCTACGATCCACGGGTGGAGGTGCGTTACTGCTCAACGGCCGCCGTTCTGGCGCAG
GCCGGGCTCGGCATTGCCGTCGTCGACCCCTATACGGCGGAATTTCACCATTCGCCGGAGCTGGTCCAGCGTCCGTTCAG
CCCGCCCTGTGAGATTTCCGTGGTGCTGCTGCTGCGCAAGGGCGTGCCGCGCTCGCGCCTCGTGCATAGCTTCATCGAGG
AATTGCGGCGACAGTTCCGCGCGCCGCCTTCGGGTTGA

Upstream 100 bases:

>100_bases
CCCAGCGCGGCATTCTGGAAGAGGCGCTGGGCATTCCGGTGGTGGATGCCACGCAGGCCGCCGTGGCGCAGGCCCTCGGC
CGGGTGCTCGTGGGCGGCTG

Downstream 100 bases:

>100_bases
CGCGCGCGCCCGCTTCGTTCATGGCCGGCACAAGCTCGGCTTTATCTCTCGCGAGACGGGTTGTGCCCGCCGCGCGCTAC
CCTGGAGTTCTGTCATGGAC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MREGDEPQVSLSLLEIFGAMMRCQTTVEAAEQLGISQPAVSNGLRQLERELGITLFERAHRRLEPTAEALSLYEEIRPLF
GVLRSFSLRARDIRQGKSGRIRIVATPPIGHTAAPRALRALLEERPEVSVSYDVRRLSDILAALKEGSADVGIALAIDQD
LDVNVEVLHRTHMVALVPVGSALANRSEVTASEVAGHRFVGLEAASRLGQILRSAFDRDHATYDPRVEVRYCSTAAVLAQ
AGLGIAVVDPYTAEFHHSPELVQRPFSPPCEISVVLLLRKGVPRSRLVHSFIEELRRQFRAPPSG

Sequences:

>Translated_305_residues
MREGDEPQVSLSLLEIFGAMMRCQTTVEAAEQLGISQPAVSNGLRQLERELGITLFERAHRRLEPTAEALSLYEEIRPLF
GVLRSFSLRARDIRQGKSGRIRIVATPPIGHTAAPRALRALLEERPEVSVSYDVRRLSDILAALKEGSADVGIALAIDQD
LDVNVEVLHRTHMVALVPVGSALANRSEVTASEVAGHRFVGLEAASRLGQILRSAFDRDHATYDPRVEVRYCSTAAVLAQ
AGLGIAVVDPYTAEFHHSPELVQRPFSPPCEISVVLLLRKGVPRSRLVHSFIEELRRQFRAPPSG
>Mature_305_residues
MREGDEPQVSLSLLEIFGAMMRCQTTVEAAEQLGISQPAVSNGLRQLERELGITLFERAHRRLEPTAEALSLYEEIRPLF
GVLRSFSLRARDIRQGKSGRIRIVATPPIGHTAAPRALRALLEERPEVSVSYDVRRLSDILAALKEGSADVGIALAIDQD
LDVNVEVLHRTHMVALVPVGSALANRSEVTASEVAGHRFVGLEAASRLGQILRSAFDRDHATYDPRVEVRYCSTAAVLAQ
AGLGIAVVDPYTAEFHHSPELVQRPFSPPCEISVVLLLRKGVPRSRLVHSFIEELRRQFRAPPSG

Specific function: Positive regulatory protein for the noc operon involved in nopaline catabolism and uptake [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789204, Length=284, Percent_Identity=29.5774647887324, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI145693105, Length=238, Percent_Identity=23.109243697479, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788748, Length=296, Percent_Identity=22.972972972973, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787879, Length=231, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788887, Length=274, Percent_Identity=23.7226277372263, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788481, Length=241, Percent_Identity=23.6514522821577, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33557; Mature: 33557

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREGDEPQVSLSLLEIFGAMMRCQTTVEAAEQLGISQPAVSNGLRQLERELGITLFERAH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHH
RRLEPTAEALSLYEEIRPLFGVLRSFSLRARDIRQGKSGRIRIVATPPIGHTAAPRALRA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHH
LLEERPEVSVSYDVRRLSDILAALKEGSADVGIALAIDQDLDVNVEVLHRTHMVALVPVG
HHHHCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHEEEEEECC
SALANRSEVTASEVAGHRFVGLEAASRLGQILRSAFDRDHATYDPRVEVRYCSTAAVLAQ
HHHHCCHHHHHHHHCCCCEECHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHH
AGLGIAVVDPYTAEFHHSPELVQRPFSPPCEISVVLLLRKGVPRSRLVHSFIEELRRQFR
CCCCEEEECCCCHHHCCCHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
APPSG
CCCCC
>Mature Secondary Structure
MREGDEPQVSLSLLEIFGAMMRCQTTVEAAEQLGISQPAVSNGLRQLERELGITLFERAH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHH
RRLEPTAEALSLYEEIRPLFGVLRSFSLRARDIRQGKSGRIRIVATPPIGHTAAPRALRA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHH
LLEERPEVSVSYDVRRLSDILAALKEGSADVGIALAIDQDLDVNVEVLHRTHMVALVPVG
HHHHCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHEEEEEECC
SALANRSEVTASEVAGHRFVGLEAASRLGQILRSAFDRDHATYDPRVEVRYCSTAAVLAQ
HHHHCCHHHHHHHHCCCCEECHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHH
AGLGIAVVDPYTAEFHHSPELVQRPFSPPCEISVVLLLRKGVPRSRLVHSFIEELRRQFR
CCCCEEEECCCCHHHCCCHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
APPSG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1799698; 11743193; 11743194 [H]