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The map label for this gene is rfbC [H]

Identifier: 158423458

GI number: 158423458

Start: 2098860

End: 2099417

Strand: Reverse

Name: rfbC [H]

Synonym: AZC_1834

Alternate gene names: 158423458

Gene position: 2099417-2098860 (Counterclockwise)

Preceding gene: 158423459

Following gene: 158423457

Centisome position: 39.1

GC content: 63.98

Gene sequence:

>558_bases
ATGACTTCGATCACCCGCCTCGACATTCCCGAGGTCGTGCTTATCACCCCGCCCCGCTTCGCAGATCCCCGTGGGTATTT
CAGCGAGACCTACAAGAAGTCCGCGCTCGACGCTGCCGGTCTGAACCACGTCTTTATCCAGGACAACGAGTCGCTCTCCA
CCGTCCCCGGCATCATCCGCGGCCTGCATTTCCAGGCCCCGCCCTTCTCCCAGGCCAAGCTCGTGCGCGTGGTGTCGGGT
GCCATCTATGACGTGGCGGTGGACATCCGGAAGGGCTCGCCCACCTACGGCAAATGGGTCGGCGCGACGCTGACAGCGGA
AAAGGGCGAGCAGATCCTCATCCCGCACGGCTTCGCCCACGCCTTCTGCACGCTGACCCCCGACGTGCGCGTGCTCTACA
AGGTGGACGGCGCCTATTCCAAGGCGAGCGAGGGCGGGATCATCTGGAACGACCCGGATCTGGCCATCGACTGGCCCGTG
TCGAACGCGCTCGTCTCCGAGAAGGACGAGATCCTGCCGCGTTTCAAGGATCTCGACAGCCCCTTCATCTACGCCTGA

Upstream 100 bases:

>100_bases
GCTTAGACAGATGGACGGCTTGACGCTAAACACGGCCGTAATCGACAAACCGCGCCGGGCTTGACCCGTCGTCCTCGATT
TGGCGGAGACGCTGGACCAC

Downstream 100 bases:

>100_bases
GGTGGACAACATGGCCAAGCGTGTTCTCGTCACCGGCGGCGCCGGCTTCATCGGATCGGCCGTGGTGCGCCATCTCGTCG
CCACCGGCGCCACGGTCCTC

Product: dTDP-6-deoxy-D-glucose-3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MTSITRLDIPEVVLITPPRFADPRGYFSETYKKSALDAAGLNHVFIQDNESLSTVPGIIRGLHFQAPPFSQAKLVRVVSG
AIYDVAVDIRKGSPTYGKWVGATLTAEKGEQILIPHGFAHAFCTLTPDVRVLYKVDGAYSKASEGGIIWNDPDLAIDWPV
SNALVSEKDEILPRFKDLDSPFIYA

Sequences:

>Translated_185_residues
MTSITRLDIPEVVLITPPRFADPRGYFSETYKKSALDAAGLNHVFIQDNESLSTVPGIIRGLHFQAPPFSQAKLVRVVSG
AIYDVAVDIRKGSPTYGKWVGATLTAEKGEQILIPHGFAHAFCTLTPDVRVLYKVDGAYSKASEGGIIWNDPDLAIDWPV
SNALVSEKDEILPRFKDLDSPFIYA
>Mature_184_residues
TSITRLDIPEVVLITPPRFADPRGYFSETYKKSALDAAGLNHVFIQDNESLSTVPGIIRGLHFQAPPFSQAKLVRVVSGA
IYDVAVDIRKGSPTYGKWVGATLTAEKGEQILIPHGFAHAFCTLTPDVRVLYKVDGAYSKASEGGIIWNDPDLAIDWPVS
NALVSEKDEILPRFKDLDSPFIYA

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=178, Percent_Identity=43.2584269662921, Blast_Score=151, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17550412, Length=175, Percent_Identity=43.4285714285714, Blast_Score=129, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20305; Mature: 20174

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSITRLDIPEVVLITPPRFADPRGYFSETYKKSALDAAGLNHVFIQDNESLSTVPGIIR
CCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHH
GLHFQAPPFSQAKLVRVVSGAIYDVAVDIRKGSPTYGKWVGATLTAEKGEQILIPHGFAH
HCCCCCCCCCHHHHHHHHHCCEEEEEEEEECCCCCCCCEEEEEEECCCCCEEEEECCCCE
AFCTLTPDVRVLYKVDGAYSKASEGGIIWNDPDLAIDWPVSNALVSEKDEILPRFKDLDS
EEEEECCCEEEEEEECCCCCCCCCCCEEECCCCEEEECCCCCCHHCCHHHHHHHHHCCCC
PFIYA
CEECC
>Mature Secondary Structure 
TSITRLDIPEVVLITPPRFADPRGYFSETYKKSALDAAGLNHVFIQDNESLSTVPGIIR
CCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHH
GLHFQAPPFSQAKLVRVVSGAIYDVAVDIRKGSPTYGKWVGATLTAEKGEQILIPHGFAH
HCCCCCCCCCHHHHHHHHHCCEEEEEEEEECCCCCCCCEEEEEEECCCCCEEEEECCCCE
AFCTLTPDVRVLYKVDGAYSKASEGGIIWNDPDLAIDWPVSNALVSEKDEILPRFKDLDS
EEEEECCCEEEEEEECCCCCCCCCCCEEECCCCEEEECCCCCCHHCCHHHHHHHHHCCCC
PFIYA
CEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8170390; 8157605; 12384590; 12704152 [H]