Click here to switch to the map view.

The map label for this gene is lolC [H]

Identifier: 158423311

GI number: 158423311

Start: 1929511

End: 1930833

Strand: Direct

Name: lolC [H]

Synonym: AZC_1687

Alternate gene names: 158423311

Gene position: 1929511-1930833 (Clockwise)

Preceding gene: 158423310

Following gene: 158423312

Centisome position: 35.93

GC content: 64.85

Gene sequence:

>1323_bases
ATGACGGGACGGCAGCGCATGGCCGCAGCCAAGGGTTCGCGGGCCGCCCCGCCGGACGCCGAACCCATGGGCACACGGCC
ATTCGCTGCCTTCGAATGGATGCTCTCCCTGCGTTACCTCCGGGCGCGGCGCAAGGAGGGCTTCATCTCGGTCATCGCCG
GCTTTTCCTTCGTGGGCATCGTGCTGGGCGTCGCCACGCTCATCATCGTCATGGCAGTGATGAACGGCTTCCGGCAGGAA
CTGCTGGGCAAGATCCTCGGCCTCAACGGCCACATGCTCGTGCAGCCGCTGGAGAATGCGCTCACCGACTATACGGCGGT
CGCGGACCGTATCTCCAAGCTCAACGGCATCAAGCTGGCGGTGCCGGTGGTGGAGGGGCAGGCGCTCGCCTCCTCGCCCT
ACAATGCCTCCGGCGTTCTGGTGCGCGGCCTTGCCGAGAAGGACCTCCGGTCCATGCCCTCGGTCGCGAACAACATCCGC
CAGGGCACGCTGGACGGCTTCGATCAGGGGCAGGGGCTCGCCATCGGCAAGCGCCTCGCCGACCAGCTCTCGCTGAGGGC
GGGTGACAACATCACGCTGGTGGCCCCGCGTGGCTCGGTGACACCGATGGGCACCTCACCCCGCATCAAGGTCTACAAGA
TCGCGGCGGTGTTCGAGATCGGCATGTCGGAATATGACAGCGCCTTCGTCTTCATGCCGCTGCCCGAGGCGCAGGCCTAT
TTCAACCGCAATGGCGATGTGAACGCCATCGAGGTCTATATCGCCAATCCCGACGATGTGGGTGAACTGCGTGGCGCTGT
GCAGGCGGCGGCGCAGCGGCCGGTCTATATCGTCGACTGGCGGCAACGGAACGCCACCTTCTTCAACGCGCTCCAGGTGG
AGCGGAACGTGATGTTCCTCATCCTCACGCTCATCGTGCTGGTGGCGGCGCTGAACATCATCTCCGGCCTCATCATGCTG
GTGAAGGACAAGGGCCACGACATCGCCGTGTTGCGCACCATGGGCGCGACGCAGGGCGCGATCATGCGCATCTTCCTCAT
CACCGGCGCCAGCATCGGCGTGGTCGGCACGCTGGTGGGCGTGTTGCTGGGCGTGGTGGTGTGCCTCAATATCGAGGAGA
TCCGTCAGTTCATCTCCTGGATGACGCGCACCGAATTGTTCTCGCCGGAGCTTTATTACCTCAGCCGCCTGCCGGCGCAG
ATGGACATGCGCGAGACGCTCTCCGTCGTCTTCATGGCGCTAACCCTCTCGCTGCTCGCGACCCTCTATCCCTCCTGGCG
GGCGGCCCGGCTCGATCCGGTGGAAGCCCTGAGATACGAATGA

Upstream 100 bases:

>100_bases
GGCCGAAGAGCCTCGCCGACGGCAAGGTGGAACTGAAGCGGCGTGTGGACGGCTCGCGCGAGCTGGTCACGCCCGCCGAG
GCATTCGAGAGGCTCAAGGG

Downstream 100 bases:

>100_bases
TGCCCGAGCCCGACTTTCCGCCGGCCCTGGCCCTCGTCAATGTCGCCCGCCGCTACAAGGAGGGGGAGGGCGCCATCGAG
GTGCTGCGCGACGCCAATCT

Product: lipoprotein releasing system transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MTGRQRMAAAKGSRAAPPDAEPMGTRPFAAFEWMLSLRYLRARRKEGFISVIAGFSFVGIVLGVATLIIVMAVMNGFRQE
LLGKILGLNGHMLVQPLENALTDYTAVADRISKLNGIKLAVPVVEGQALASSPYNASGVLVRGLAEKDLRSMPSVANNIR
QGTLDGFDQGQGLAIGKRLADQLSLRAGDNITLVAPRGSVTPMGTSPRIKVYKIAAVFEIGMSEYDSAFVFMPLPEAQAY
FNRNGDVNAIEVYIANPDDVGELRGAVQAAAQRPVYIVDWRQRNATFFNALQVERNVMFLILTLIVLVAALNIISGLIML
VKDKGHDIAVLRTMGATQGAIMRIFLITGASIGVVGTLVGVLLGVVVCLNIEEIRQFISWMTRTELFSPELYYLSRLPAQ
MDMRETLSVVFMALTLSLLATLYPSWRAARLDPVEALRYE

Sequences:

>Translated_440_residues
MTGRQRMAAAKGSRAAPPDAEPMGTRPFAAFEWMLSLRYLRARRKEGFISVIAGFSFVGIVLGVATLIIVMAVMNGFRQE
LLGKILGLNGHMLVQPLENALTDYTAVADRISKLNGIKLAVPVVEGQALASSPYNASGVLVRGLAEKDLRSMPSVANNIR
QGTLDGFDQGQGLAIGKRLADQLSLRAGDNITLVAPRGSVTPMGTSPRIKVYKIAAVFEIGMSEYDSAFVFMPLPEAQAY
FNRNGDVNAIEVYIANPDDVGELRGAVQAAAQRPVYIVDWRQRNATFFNALQVERNVMFLILTLIVLVAALNIISGLIML
VKDKGHDIAVLRTMGATQGAIMRIFLITGASIGVVGTLVGVLLGVVVCLNIEEIRQFISWMTRTELFSPELYYLSRLPAQ
MDMRETLSVVFMALTLSLLATLYPSWRAARLDPVEALRYE
>Mature_439_residues
TGRQRMAAAKGSRAAPPDAEPMGTRPFAAFEWMLSLRYLRARRKEGFISVIAGFSFVGIVLGVATLIIVMAVMNGFRQEL
LGKILGLNGHMLVQPLENALTDYTAVADRISKLNGIKLAVPVVEGQALASSPYNASGVLVRGLAEKDLRSMPSVANNIRQ
GTLDGFDQGQGLAIGKRLADQLSLRAGDNITLVAPRGSVTPMGTSPRIKVYKIAAVFEIGMSEYDSAFVFMPLPEAQAYF
NRNGDVNAIEVYIANPDDVGELRGAVQAAAQRPVYIVDWRQRNATFFNALQVERNVMFLILTLIVLVAALNIISGLIMLV
KDKGHDIAVLRTMGATQGAIMRIFLITGASIGVVGTLVGVLLGVVVCLNIEEIRQFISWMTRTELFSPELYYLSRLPAQM
DMRETLSVVFMALTLSLLATLYPSWRAARLDPVEALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=405, Percent_Identity=31.358024691358, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1787360, Length=417, Percent_Identity=30.2158273381295, Blast_Score=166, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 47999; Mature: 47868

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGRQRMAAAKGSRAAPPDAEPMGTRPFAAFEWMLSLRYLRARRKEGFISVIAGFSFVGI
CCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VLGVATLIIVMAVMNGFRQELLGKILGLNGHMLVQPLENALTDYTAVADRISKLNGIKLA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCEEE
VPVVEGQALASSPYNASGVLVRGLAEKDLRSMPSVANNIRQGTLDGFDQGQGLAIGKRLA
EEEECCCHHCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
DQLSLRAGDNITLVAPRGSVTPMGTSPRIKVYKIAAVFEIGMSEYDSAFVFMPLPEAQAY
HHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCEEEEEECCHHHHH
FNRNGDVNAIEVYIANPDDVGELRGAVQAAAQRPVYIVDWRQRNATFFNALQVERNVMFL
HCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHH
ILTLIVLVAALNIISGLIMLVKDKGHDIAVLRTMGATQGAIMRIFLITGASIGVVGTLVG
HHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCHHHHEEHHHHCCHHHHHHHHHH
VLLGVVVCLNIEEIRQFISWMTRTELFSPELYYLSRLPAQMDMRETLSVVFMALTLSLLA
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
TLYPSWRAARLDPVEALRYE
HHCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure 
TGRQRMAAAKGSRAAPPDAEPMGTRPFAAFEWMLSLRYLRARRKEGFISVIAGFSFVGI
CCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VLGVATLIIVMAVMNGFRQELLGKILGLNGHMLVQPLENALTDYTAVADRISKLNGIKLA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCEEE
VPVVEGQALASSPYNASGVLVRGLAEKDLRSMPSVANNIRQGTLDGFDQGQGLAIGKRLA
EEEECCCHHCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
DQLSLRAGDNITLVAPRGSVTPMGTSPRIKVYKIAAVFEIGMSEYDSAFVFMPLPEAQAY
HHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCEEEEEECCHHHHH
FNRNGDVNAIEVYIANPDDVGELRGAVQAAAQRPVYIVDWRQRNATFFNALQVERNVMFL
HCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHH
ILTLIVLVAALNIISGLIMLVKDKGHDIAVLRTMGATQGAIMRIFLITGASIGVVGTLVG
HHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCHHHHEEHHHHCCHHHHHHHHHH
VLLGVVVCLNIEEIRQFISWMTRTELFSPELYYLSRLPAQMDMRETLSVVFMALTLSLLA
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
TLYPSWRAARLDPVEALRYE
HHCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]