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The map label for this gene is yciA [H]

Identifier: 158423244

GI number: 158423244

Start: 1849325

End: 1849711

Strand: Reverse

Name: yciA [H]

Synonym: AZC_1620

Alternate gene names: 158423244

Gene position: 1849711-1849325 (Counterclockwise)

Preceding gene: 158423245

Following gene: 158423243

Centisome position: 34.45

GC content: 69.51

Gene sequence:

>387_bases
ATGCCCGATACGGCCGAACCCACCGGCGAACTCACCCTGCGCACGCTCGCCATGCCGGCGGACGCCAATCCGTCCGGCGA
CATCTTCGGCGGCTGGGTGATGGCGCAGATGGACCTTGCGGCGGGCATCCGCGCCGCCGAGGTGGCCGCCGGCCGCGTCG
TGACGGCGGGTGTGAAGGAAATCAACTTCCGCCTGCCGGTGAAGGTGGGCGACACCATGTGCATCTACACCAACCTGCTG
AAGGTGGGCCGCACCTCCATGACGCTGGACGTGCAAGCCTGGGCGCGCCGCCAGCACAGCGCCGTCCGCGAGAAGGTGAC
GGAGGCCGTTTTCGTGATGGTGGCGCTTGATGCCGAGGGGCGCCCGCGTCCGGTGTCTCCGGCCTGA

Upstream 100 bases:

>100_bases
GCAGGATGGTGGGCTTGGGGCCGCGTCGTAGGCGGCTCTTGCCTCCCCCGCCATTACGGGCCTACCAAGCACAGGTTGTC
CTGCGGAGCTGGAGCCCGAA

Downstream 100 bases:

>100_bases
GACGGCGGTTTGTCCTTTCCTGCTCCCGCGCCTGGCGAAAATCCCATGCAGCTGCATCTGCCGGAAGCCTATGACCTGAG
CGACTACGAGGCTCTGGCGC

Product: acyl-CoA hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 128; Mature: 127

Protein sequence:

>128_residues
MPDTAEPTGELTLRTLAMPADANPSGDIFGGWVMAQMDLAAGIRAAEVAAGRVVTAGVKEINFRLPVKVGDTMCIYTNLL
KVGRTSMTLDVQAWARRQHSAVREKVTEAVFVMVALDAEGRPRPVSPA

Sequences:

>Translated_128_residues
MPDTAEPTGELTLRTLAMPADANPSGDIFGGWVMAQMDLAAGIRAAEVAAGRVVTAGVKEINFRLPVKVGDTMCIYTNLL
KVGRTSMTLDVQAWARRQHSAVREKVTEAVFVMVALDAEGRPRPVSPA
>Mature_127_residues
PDTAEPTGELTLRTLAMPADANPSGDIFGGWVMAQMDLAAGIRAAEVAAGRVVTAGVKEINFRLPVKVGDTMCIYTNLLK
VGRTSMTLDVQAWARRQHSAVREKVTEAVFVMVALDAEGRPRPVSPA

Specific function: Catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA [H]

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1787506, Length=120, Percent_Identity=50, Blast_Score=126, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 13680; Mature: 13549

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDTAEPTGELTLRTLAMPADANPSGDIFGGWVMAQMDLAAGIRAAEVAAGRVVTAGVKE
CCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCEEEECCCEE
INFRLPVKVGDTMCIYTNLLKVGRTSMTLDVQAWARRQHSAVREKVTEAVFVMVALDAEG
CEEEECEEECCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHEEEEEEECCCC
RPRPVSPA
CCCCCCCC
>Mature Secondary Structure 
PDTAEPTGELTLRTLAMPADANPSGDIFGGWVMAQMDLAAGIRAAEVAAGRVVTAGVKE
CCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCEEEECCCEE
INFRLPVKVGDTMCIYTNLLKVGRTSMTLDVQAWARRQHSAVREKVTEAVFVMVALDAEG
CEEEECEEECCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHEEEEEEECCCC
RPRPVSPA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]