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The map label for this gene is mcp2 [H]

Identifier: 158423170

GI number: 158423170

Start: 1757925

End: 1759400

Strand: Direct

Name: mcp2 [H]

Synonym: AZC_1546

Alternate gene names: 158423170

Gene position: 1757925-1759400 (Clockwise)

Preceding gene: 158423169

Following gene: 158423171

Centisome position: 32.74

GC content: 64.91

Gene sequence:

>1476_bases
ATGGCCGTTGCTGCATTTCCGTTTCGCCGTGACACCGCTTCGATCGGTGCAGCGGCGCAGTTCCTCGACAATCTGCCTTC
CGCGGTCATGCTCTGCGAACCGCAGAATCTGGTGATCTGCTATCTCAACAAGGCTTCGGTCCAGCTCCTCAAATCCATTG
AGCATGTCCTGCCCGTGAAGGCGGACCAGGTGCTGGGCTCTTCCATCGACATCTTTCACAAGAACCCTTCGCACCAGCGC
CGCCTCCTCGCCGATCCGAAGAACCTGCCCCACACCGCGCGGATCAAGGCGGGCGACGAGATTCTTGAGCTCAACATCAA
TGCGGTGCGCGACGCCCGCGGCGCCTATGCCTATGTTCAGCTCACCTGGAGCGTCATCACCAAGGCCGTCGAGCATGAGG
AGAAGACCGAGCGTCTGCTCCAGATGATCGAGGAAATGCCGATCAACGTGATGACCTGCACCCTCGACGATTTCCGCATC
GATTTTGCGAATCGCGCCAGCCGCGAGACGCTCAAGCGCATCGAGCAGTATCTGCCGGTGAAGGCCGCCGATCTCATCGG
CACCTCCATCGACGTGTTTCACAAGGCCCCGGCCCACCAGCGCCGGATGCTCGCGGACCCCTCGAACCTGCCGCATCAGG
CCAACATCAAGGTCGGACCCGAGACGCTGCGCCTGCGCGTTTCGGCCATCAAGGACCAGAAGGGCAACTATGTGGGCCCC
ATGGTCACCTGGGCGGTGGTCACCGAGAGCGTTGCGCTCGCCAACAGCGTCAACGAGGTGGTCGGGTCCATGACCGACAC
TTCGGCCGAGATGCAGCAGTCCAGCTCGCGCCTGCTCGAACTGACGCAGAGCTCCGACCAGACGGCAGCGGCCGTCTCCG
CCGCGGCGGTGGAGATGTCCGCCTCCTTCGACGAGATTTCCAGCCAGATCCGGCAGGCCACGGGCATGTCGCAGGATGTG
GCCGAGCGCGCCCGCTCGACCGACCAGCTGGTGAGCGGCCTCACCGAGAGCGTGGAGCGCATCGGCGCCTTCACGGCCCT
CATCGACAAGATCGCGGCGCAGACCAACCTTCTCGCGCTGAACGCCACCATCGAGGCGGCGCGCGTGGGCGAGGCCGGCA
AGGGATTCGCGGTGGTGGCGCAGGAGGTGAAGGCGCTCGCCATGCAGACGGCGAATGCCACGCAGGACATTCGCCAGCAG
GTCTCTGCCGTCCAGACCGCCAGCGAGGCAGCGGCGACGGCCGTCTCCGACATCTCCGGCAACGTGCGCCAGTTGAGCGA
GGTCTTCACTGCTCTGTCGGCGGGCGTCGAGGAACAGGTGGTCACCAACCGTTCGGTGAGCCAGATGATCACCGGCGTCT
CCGACACCACCGGCGAAATCCGGGACGCCGCGCTGCGGGTGCGCTCGGTTGCCGATCAGGTGGGGGGGTGCGCGGGACGG
CTCACCAACGAGGTGGGAACGCTTCTCAAGACCTGA

Upstream 100 bases:

>100_bases
GGTCCATTGCCTACACAACCTTTAGTCGTATGGTGGCGCTGGAACATGATCGCGGTCTTGTCTGGACGGCGGCACCCCAC
ACGAGAAAAAGGGGGGCTCC

Downstream 100 bases:

>100_bases
TCCGGACCGCCGCGCGGAACAGGCGGGCGGAGCATTGGTTGATCTCCCGGGGCACCGAGGAGGTCACCCATGACCATCGC
CCGCACGCGCCATCCGGCTG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MAVAAFPFRRDTASIGAAAQFLDNLPSAVMLCEPQNLVICYLNKASVQLLKSIEHVLPVKADQVLGSSIDIFHKNPSHQR
RLLADPKNLPHTARIKAGDEILELNINAVRDARGAYAYVQLTWSVITKAVEHEEKTERLLQMIEEMPINVMTCTLDDFRI
DFANRASRETLKRIEQYLPVKAADLIGTSIDVFHKAPAHQRRMLADPSNLPHQANIKVGPETLRLRVSAIKDQKGNYVGP
MVTWAVVTESVALANSVNEVVGSMTDTSAEMQQSSSRLLELTQSSDQTAAAVSAAAVEMSASFDEISSQIRQATGMSQDV
AERARSTDQLVSGLTESVERIGAFTALIDKIAAQTNLLALNATIEAARVGEAGKGFAVVAQEVKALAMQTANATQDIRQQ
VSAVQTASEAAATAVSDISGNVRQLSEVFTALSAGVEEQVVTNRSVSQMITGVSDTTGEIRDAALRVRSVADQVGGCAGR
LTNEVGTLLKT

Sequences:

>Translated_491_residues
MAVAAFPFRRDTASIGAAAQFLDNLPSAVMLCEPQNLVICYLNKASVQLLKSIEHVLPVKADQVLGSSIDIFHKNPSHQR
RLLADPKNLPHTARIKAGDEILELNINAVRDARGAYAYVQLTWSVITKAVEHEEKTERLLQMIEEMPINVMTCTLDDFRI
DFANRASRETLKRIEQYLPVKAADLIGTSIDVFHKAPAHQRRMLADPSNLPHQANIKVGPETLRLRVSAIKDQKGNYVGP
MVTWAVVTESVALANSVNEVVGSMTDTSAEMQQSSSRLLELTQSSDQTAAAVSAAAVEMSASFDEISSQIRQATGMSQDV
AERARSTDQLVSGLTESVERIGAFTALIDKIAAQTNLLALNATIEAARVGEAGKGFAVVAQEVKALAMQTANATQDIRQQ
VSAVQTASEAAATAVSDISGNVRQLSEVFTALSAGVEEQVVTNRSVSQMITGVSDTTGEIRDAALRVRSVADQVGGCAGR
LTNEVGTLLKT
>Mature_490_residues
AVAAFPFRRDTASIGAAAQFLDNLPSAVMLCEPQNLVICYLNKASVQLLKSIEHVLPVKADQVLGSSIDIFHKNPSHQRR
LLADPKNLPHTARIKAGDEILELNINAVRDARGAYAYVQLTWSVITKAVEHEEKTERLLQMIEEMPINVMTCTLDDFRID
FANRASRETLKRIEQYLPVKAADLIGTSIDVFHKAPAHQRRMLADPSNLPHQANIKVGPETLRLRVSAIKDQKGNYVGPM
VTWAVVTESVALANSVNEVVGSMTDTSAEMQQSSSRLLELTQSSDQTAAAVSAAAVEMSASFDEISSQIRQATGMSQDVA
ERARSTDQLVSGLTESVERIGAFTALIDKIAAQTNLLALNATIEAARVGEAGKGFAVVAQEVKALAMQTANATQDIRQQV
SAVQTASEAAATAVSDISGNVRQLSEVFTALSAGVEEQVVTNRSVSQMITGVSDTTGEIRDAALRVRSVADQVGGCAGRL
TNEVGTLLKT

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=216, Percent_Identity=34.2592592592593, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1788195, Length=231, Percent_Identity=31.6017316017316, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788194, Length=244, Percent_Identity=30.7377049180328, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787690, Length=224, Percent_Identity=30.8035714285714, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI2367378, Length=193, Percent_Identity=30.0518134715026, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 52777; Mature: 52645

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVAAFPFRRDTASIGAAAQFLDNLPSAVMLCEPQNLVICYLNKASVQLLKSIEHVLPVK
CCEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECHHHHHHHHHHHHHCCCC
ADQVLGSSIDIFHKNPSHQRRLLADPKNLPHTARIKAGDEILELNINAVRDARGAYAYVQ
HHHHCCCCEEEEECCCCHHHHHHCCCCCCCCCEEECCCCEEEEEEHHHHHCCCCCEEEEE
LTWSVITKAVEHEEKTERLLQMIEEMPINVMTCTLDDFRIDFANRASRETLKRIEQYLPV
EHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHEECHHHHHHHHHHHHHHHHCCC
KAADLIGTSIDVFHKAPAHQRRMLADPSNLPHQANIKVGPETLRLRVSAIKDQKGNYVGP
HHHHHHCCCHHHHHCCCHHHHHHCCCCCCCCCCCCEEECHHHHHHHHHHHHCCCCCCCCH
MVTWAVVTESVALANSVNEVVGSMTDTSAEMQQSSSRLLELTQSSDQTAAAVSAAAVEMS
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ASFDEISSQIRQATGMSQDVAERARSTDQLVSGLTESVERIGAFTALIDKIAAQTNLLAL
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
NATIEAARVGEAGKGFAVVAQEVKALAMQTANATQDIRQQVSAVQTASEAAATAVSDISG
ECCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NVRQLSEVFTALSAGVEEQVVTNRSVSQMITGVSDTTGEIRDAALRVRSVADQVGGCAGR
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHH
LTNEVGTLLKT
HHHHHHHHHCC
>Mature Secondary Structure 
AVAAFPFRRDTASIGAAAQFLDNLPSAVMLCEPQNLVICYLNKASVQLLKSIEHVLPVK
CEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECHHHHHHHHHHHHHCCCC
ADQVLGSSIDIFHKNPSHQRRLLADPKNLPHTARIKAGDEILELNINAVRDARGAYAYVQ
HHHHCCCCEEEEECCCCHHHHHHCCCCCCCCCEEECCCCEEEEEEHHHHHCCCCCEEEEE
LTWSVITKAVEHEEKTERLLQMIEEMPINVMTCTLDDFRIDFANRASRETLKRIEQYLPV
EHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHEECHHHHHHHHHHHHHHHHCCC
KAADLIGTSIDVFHKAPAHQRRMLADPSNLPHQANIKVGPETLRLRVSAIKDQKGNYVGP
HHHHHHCCCHHHHHCCCHHHHHHCCCCCCCCCCCCEEECHHHHHHHHHHHHCCCCCCCCH
MVTWAVVTESVALANSVNEVVGSMTDTSAEMQQSSSRLLELTQSSDQTAAAVSAAAVEMS
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ASFDEISSQIRQATGMSQDVAERARSTDQLVSGLTESVERIGAFTALIDKIAAQTNLLAL
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
NATIEAARVGEAGKGFAVVAQEVKALAMQTANATQDIRQQVSAVQTASEAAATAVSDISG
ECCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NVRQLSEVFTALSAGVEEQVVTNRSVSQMITGVSDTTGEIRDAALRVRSVADQVGGCAGR
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHH
LTNEVGTLLKT
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]