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The map label for this gene is prsA [H]

Identifier: 158423053

GI number: 158423053

Start: 1630166

End: 1631080

Strand: Direct

Name: prsA [H]

Synonym: AZC_1429

Alternate gene names: 158423053

Gene position: 1630166-1631080 (Clockwise)

Preceding gene: 158423052

Following gene: 158423054

Centisome position: 30.36

GC content: 71.58

Gene sequence:

>915_bases
GTGAAGGCCATGGTTACGCTCGTCATCGACCATGCCGCCACCCGCGCCGATCATTCCCACGACCACCCCCATGAGCACGC
GCCGCTGGCACGGGACACGGCGCCCTCGCGGGAGCGGGTGGTCATGTCCCCGGTCAGCGTCAACGGCGTTGCCATTTCCC
GCAAGGCCATTGCCGCCGAGGTGCAGAACGCCCCGGCCAAGACCCCGGCGGAAGGCTGGTTCAATGCCACGCTGGCGCTT
GTGGTGCGGGAACTGCTGCTGCAGGAGGCCCATCGCCTCGGCCTTTCCGCCGATCCGCGCCTTGAGGCGGACGGCCGGCG
GGAGACCGAGGAGGAGGCACTGATCCGCGCCCTTCTGGCGCAGGAGGTGCGCACGCCGGAGGCGGACGAGGCGGCGCTCC
GCCGCTTCTACGACAACAACCGGCGGCGTTTCCTGTCCGCGCCCCTCTGGGAGGCGGAGCACATCCTGTGCGCCGCCCGC
CGGGAGGACGCGGTGGCCTTCCCGGCGGCGCGCGAGCGGGCGCAGACCCTCGCGGCTGTTCTGGCCCGTGCACCGGAGCG
CTTCGCCGAGCTGGCGCGGGCGCAGTCCGATTGCCCCTCTGCCGGGGTCGGCGGCAGCCTCGGCCAGATCGGACCGGGCG
ATACGACGCCGGAGTTCGAGGCGGCGCTGAAGGCATTGACGCCGGGCGTGATCTCCGAGCCGGTAGAGACGCGCTACGGC
GTCCACCTCATCCGCGTGAACCGTCATGTGGACGGCCGCACGCTGCCCTTCGAGGCGGTGCGCGATCAGATCGCCGCTTA
TCTCGCCGACCATGTGACCCGTGCGGCGCATGCCCAGTACGTCGCGCTGCTCATCGGCCGGGCGGACATTCAGGGCATCG
CGCTCGGCGGCGCGGATAGCCCGCTCGTGCAGTAG

Upstream 100 bases:

>100_bases
GCTTCGCCCATGGCTCCGGCCAGCCGCGCCGCACGGCATCCGCGCCGGTCGTCGCTCCGGCGCCCCGTGCCACGTCCATT
CCCGCACAGCGTCCGGCGGA

Downstream 100 bases:

>100_bases
GAGGTTGCCATGTTCGGCGCGCTGCTCTCCACGCTGGAAGATCCGCAGGTGTGCGAACGCCTTCTTTCGACGCTCGATGC
GCCGAGCCTCTCCGCCCGCC

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MKAMVTLVIDHAATRADHSHDHPHEHAPLARDTAPSRERVVMSPVSVNGVAISRKAIAAEVQNAPAKTPAEGWFNATLAL
VVRELLLQEAHRLGLSADPRLEADGRRETEEEALIRALLAQEVRTPEADEAALRRFYDNNRRRFLSAPLWEAEHILCAAR
REDAVAFPAARERAQTLAAVLARAPERFAELARAQSDCPSAGVGGSLGQIGPGDTTPEFEAALKALTPGVISEPVETRYG
VHLIRVNRHVDGRTLPFEAVRDQIAAYLADHVTRAAHAQYVALLIGRADIQGIALGGADSPLVQ

Sequences:

>Translated_304_residues
MKAMVTLVIDHAATRADHSHDHPHEHAPLARDTAPSRERVVMSPVSVNGVAISRKAIAAEVQNAPAKTPAEGWFNATLAL
VVRELLLQEAHRLGLSADPRLEADGRRETEEEALIRALLAQEVRTPEADEAALRRFYDNNRRRFLSAPLWEAEHILCAAR
REDAVAFPAARERAQTLAAVLARAPERFAELARAQSDCPSAGVGGSLGQIGPGDTTPEFEAALKALTPGVISEPVETRYG
VHLIRVNRHVDGRTLPFEAVRDQIAAYLADHVTRAAHAQYVALLIGRADIQGIALGGADSPLVQ
>Mature_304_residues
MKAMVTLVIDHAATRADHSHDHPHEHAPLARDTAPSRERVVMSPVSVNGVAISRKAIAAEVQNAPAKTPAEGWFNATLAL
VVRELLLQEAHRLGLSADPRLEADGRRETEEEALIRALLAQEVRTPEADEAALRRFYDNNRRRFLSAPLWEAEHILCAAR
REDAVAFPAARERAQTLAAVLARAPERFAELARAQSDCPSAGVGGSLGQIGPGDTTPEFEAALKALTPGVISEPVETRYG
VHLIRVNRHVDGRTLPFEAVRDQIAAYLADHVTRAAHAQYVALLIGRADIQGIALGGADSPLVQ

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

None

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 32901; Mature: 32901

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAMVTLVIDHAATRADHSHDHPHEHAPLARDTAPSRERVVMSPVSVNGVAISRKAIAAE
CCCEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEHHHHHHHH
VQNAPAKTPAEGWFNATLALVVRELLLQEAHRLGLSADPRLEADGRRETEEEALIRALLA
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
QEVRTPEADEAALRRFYDNNRRRFLSAPLWEAEHILCAARREDAVAFPAARERAQTLAAV
HHHCCCCHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHHHHH
LARAPERFAELARAQSDCPSAGVGGSLGQIGPGDTTPEFEAALKALTPGVISEPVETRYG
HHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHCCCHHHHHC
VHLIRVNRHVDGRTLPFEAVRDQIAAYLADHVTRAAHAQYVALLIGRADIQGIALGGADS
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PLVQ
CCCC
>Mature Secondary Structure
MKAMVTLVIDHAATRADHSHDHPHEHAPLARDTAPSRERVVMSPVSVNGVAISRKAIAAE
CCCEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEHHHHHHHH
VQNAPAKTPAEGWFNATLALVVRELLLQEAHRLGLSADPRLEADGRRETEEEALIRALLA
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
QEVRTPEADEAALRRFYDNNRRRFLSAPLWEAEHILCAARREDAVAFPAARERAQTLAAV
HHHCCCCHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHHHHH
LARAPERFAELARAQSDCPSAGVGGSLGQIGPGDTTPEFEAALKALTPGVISEPVETRYG
HHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHCCCHHHHHC
VHLIRVNRHVDGRTLPFEAVRDQIAAYLADHVTRAAHAQYVALLIGRADIQGIALGGADS
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PLVQ
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]