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The map label for this gene is crp [C]

Identifier: 158422926

GI number: 158422926

Start: 1455040

End: 1455843

Strand: Reverse

Name: crp [C]

Synonym: AZC_1302

Alternate gene names: 158422926

Gene position: 1455843-1455040 (Counterclockwise)

Preceding gene: 158422930

Following gene: 158422924

Centisome position: 27.11

GC content: 64.55

Gene sequence:

>804_bases
ATGTTCTTTTGGTCTTCGCTGGAAGCGGTACGATCCGACGGCACGTTAGTTGATCTGGACCGACGAGATTGCGTAGATTT
CCGCAATCTAAGCGGGAGCTTCGCCATGATCCGACCTTCCGAGTGCGATGCCCTCCGCGTGCACGGCTGGCTGTCGGAAA
CCGTCGAGACGTTCCGCAATGCCGTGCTGGAACGCTGTGTGCCAAGGCGGTTCGCGCGGGGCGAGACGCTTTATCGGGCC
GGGGACGAAGCCGGCGGTCTCTATGGGCTCGTGGATGGGGCCTTCGGCGTGATGGTCGACCCCGGAGCGTCCGCGCCCTT
TCTCGGCATCCTTGCTCGGCCCGGCTTCTGGATCGGCGAGGCCTCGGTCATCACGCGCGGACCACGGGCCATCGGCATCG
TCGCCGCGCGCGACAGCCACGTGGCCCACCTCCCTCTCAGGCAATGGGATGCCATCGCCCGGGCAGAGCCGGAGGCATGG
CGCTGGCTCGCTTATCTGACATTGCGCAACGAATTACTGGCGCTCGCCGTCATCGACGCGCTGCGCCAGCGGGGGGCCGA
GGGCCGGCTCGCTGCGATACTCGCCGTTCTGGCCATGGGCGCGGATGCCGGGGAAAAAGGCATCAACGGCACGGGGGGAA
CCGTCATCGAAATCAGTCAGGATGATCTCGCGTCCATGGCGAACCTTTCGCGTTCGACGGCCGGTCGTGTCCTGGATTCC
TTCGAGGCCTGCAGCCTCATCAAGCGAAGCTACAGGACGCTGAATATTCTCGACCTCGAAGGGCTCAAACGTCGGCGTGC
CTGA

Upstream 100 bases:

>100_bases
CTCCGATGGCGAAGGCGGCGGCGGAAGCGGGACCGGACTTCAGAATATCTCGCCGGGAAACCATTGGCATTCCTCTTTTT
ACCAAGACTCAAAGCAAGCA

Downstream 100 bases:

>100_bases
TATTGAGAAGGTTCCCAAGCCCTCGTCGCGACGAGGAGATCGGCCGACACAGACCGCCTTGCGGCGGTCGGCAGACGAAC
TGACAGCGCCGGGCACCCGG

Product: cyclic nucleotide-binding protein

Products: NA

Alternate protein names: Transcriptional Regulator; Regulatory Protein; Transcriptional Regulator Crp/Fnr Family; CRP/FNR Family Transcriptional Regulator; Transcription Regulator Protein

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MFFWSSLEAVRSDGTLVDLDRRDCVDFRNLSGSFAMIRPSECDALRVHGWLSETVETFRNAVLERCVPRRFARGETLYRA
GDEAGGLYGLVDGAFGVMVDPGASAPFLGILARPGFWIGEASVITRGPRAIGIVAARDSHVAHLPLRQWDAIARAEPEAW
RWLAYLTLRNELLALAVIDALRQRGAEGRLAAILAVLAMGADAGEKGINGTGGTVIEISQDDLASMANLSRSTAGRVLDS
FEACSLIKRSYRTLNILDLEGLKRRRA

Sequences:

>Translated_267_residues
MFFWSSLEAVRSDGTLVDLDRRDCVDFRNLSGSFAMIRPSECDALRVHGWLSETVETFRNAVLERCVPRRFARGETLYRA
GDEAGGLYGLVDGAFGVMVDPGASAPFLGILARPGFWIGEASVITRGPRAIGIVAARDSHVAHLPLRQWDAIARAEPEAW
RWLAYLTLRNELLALAVIDALRQRGAEGRLAAILAVLAMGADAGEKGINGTGGTVIEISQDDLASMANLSRSTAGRVLDS
FEACSLIKRSYRTLNILDLEGLKRRRA
>Mature_267_residues
MFFWSSLEAVRSDGTLVDLDRRDCVDFRNLSGSFAMIRPSECDALRVHGWLSETVETFRNAVLERCVPRRFARGETLYRA
GDEAGGLYGLVDGAFGVMVDPGASAPFLGILARPGFWIGEASVITRGPRAIGIVAARDSHVAHLPLRQWDAIARAEPEAW
RWLAYLTLRNELLALAVIDALRQRGAEGRLAAILAVLAMGADAGEKGINGTGGTVIEISQDDLASMANLSRSTAGRVLDS
FEACSLIKRSYRTLNILDLEGLKRRRA

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 29103; Mature: 29103

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFWSSLEAVRSDGTLVDLDRRDCVDFRNLSGSFAMIRPSECDALRVHGWLSETVETFRN
CCCCHHHHHHHCCCCEEECCCHHHHHHHCCCCCEEEECCCCCCEEEHHHHHHHHHHHHHH
AVLERCVPRRFARGETLYRAGDEAGGLYGLVDGAFGVMVDPGASAPFLGILARPGFWIGE
HHHHHHHHHHHHCCCHHEECCCCCCCEEEEECCCCEEEECCCCCCCHHHHHCCCCCEECC
ASVITRGPRAIGIVAARDSHVAHLPLRQWDAIARAEPEAWRWLAYLTLRNELLALAVIDA
HHHEECCCCEEEEEEECCCCEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LRQRGAEGRLAAILAVLAMGADAGEKGINGTGGTVIEISQDDLASMANLSRSTAGRVLDS
HHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHH
FEACSLIKRSYRTLNILDLEGLKRRRA
HHHHHHHHHHCCEEEEEECHHHHHCCC
>Mature Secondary Structure
MFFWSSLEAVRSDGTLVDLDRRDCVDFRNLSGSFAMIRPSECDALRVHGWLSETVETFRN
CCCCHHHHHHHCCCCEEECCCHHHHHHHCCCCCEEEECCCCCCEEEHHHHHHHHHHHHHH
AVLERCVPRRFARGETLYRAGDEAGGLYGLVDGAFGVMVDPGASAPFLGILARPGFWIGE
HHHHHHHHHHHHCCCHHEECCCCCCCEEEEECCCCEEEECCCCCCCHHHHHCCCCCEECC
ASVITRGPRAIGIVAARDSHVAHLPLRQWDAIARAEPEAWRWLAYLTLRNELLALAVIDA
HHHEECCCCEEEEEEECCCCEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LRQRGAEGRLAAILAVLAMGADAGEKGINGTGGTVIEISQDDLASMANLSRSTAGRVLDS
HHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHH
FEACSLIKRSYRTLNILDLEGLKRRRA
HHHHHHHHHHCCEEEEEECHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA