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The map label for this gene is hmp [H]

Identifier: 158422905

GI number: 158422905

Start: 1434891

End: 1436792

Strand: Direct

Name: hmp [H]

Synonym: AZC_1281

Alternate gene names: 158422905

Gene position: 1434891-1436792 (Clockwise)

Preceding gene: 158422904

Following gene: 158422906

Centisome position: 26.72

GC content: 57.73

Gene sequence:

>1902_bases
ATGAACCTCGATGATCATCCTACGGTCAGGCAGCTTCGCGCATCAGGTCGACTGGGCGAGACCGCAAGTATAGCTGGCCC
CATCGATGCGAATGAGTTGCGCAAGCTCGCGCTGGAGTGCGGCGCCCACGACGTCGGGCTGGTTGAAATCGGACGCACTG
AACTTGACCCGCAGCGCGACGAAATCCTCAAGAATTATCCGTGGACACGCACTCTGCTCAGCTTCGTCGTAAAGATGGTG
CGTGAGCCGGTACGCGGAACGCCGCGCTCTGTCTCCAACCTGGAATTCCACCGCGCCGGTTATGAGACCAACGAAATCGC
CGCACGCATCGTCTCTTGCCTGCAGGATAGCGGCATTCGTGCGGTGAACCCCTCCATGGGTTTTCCCATGGAAATGCAGA
ATAATCCCGGCGCGGCCATCTGGATCGTTTCGCACAAGCCGGTGGCGGTTGCAGCAGGTCTCGGTCGCATGGGTATCCAT
CGCAACCTGATTCACCCGAAGTTCGGCAACTTTGTCCTGCTGGGAACAGTCCTGCTCGATCAGGATGTCAGTGCGGTTGA
TCAGTCGATTGATTACAATCCGTGCCTTGAATGTAATCTTTGCGTGGCTGTCTGCCCGGTGGGCGCCATTAAGCCAGATG
GCGCGTTCAATTTTCAGGCCTGCTTCACCCACAATTACCGCGAGTTCATGGGTGGGTTTAACGATTGGGTCGAGCAGATC
GCTGACGCAAAGGATGCCATTGATTATCGCAAACGCGTCAACGAGCCTGAAACCGCTTCGATGTGGCAAAGCCTGACCTA
CGGAGCCAATTACAAATCCGCATACTGCCTCGCCGTTTGCCCTGCAGGCGAGGATGTGATCGGTCCGTATTTAAATGACA
AGGCTGCCCATCGCCGCGAGATTGTGCGGCCCCTCCAGGAGCGGCCGGAGACCATCTACGTCGTTGCCGGAACTGACGCT
GATCAGGTGGCCCGCCGTAAATGGAAAAACAAGACCGTCAAACCTGTCGGTAACGGTATGACGCCCCGGACAATTTCTGG
GCTCTTGACCTTCATGCCGATCGTCTTCCAGCCCGAGCAGTCGCGCGGGCTCGACGCCGTCTTTCATTTTACCTTTACCG
GCGCGGATCATCGCGACGCGACGATCACGATAAAGGACCGCAAAATCACCGTTCGCGAGGGGCTTATCGGGAAGGCTAGC
ATTCGTGTTACAGCGGATGCAAAGACCTGGCTCGGGTTCCTTGCAAAGGAAAAGAACATCGTTTGGGCGCTGGCAACGCG
AAAGATCCGCATCTCCGGCGATCCGCGGCTGCTGCTGGCGTTCGGCAAGTGCTTCCCGTCACCGGAAATCAAGCGCAAGC
ATGTCGAGGTGATCCCAGAGGCCTCGCTGATTGTGCCGGCGATACGGCCGTTTGAAAAGAACGATGCCCTAACCGGAAAA
GCTCGCTGGTACGGCGCTCTGCTTCTGAAGGATATCGAGCAGGTTACGCCGAATGTGAAGACATTCCGCTTCGTCAATCC
TAAGGGCGGCGACATTCCGTTCACCCATGTTGCGGGCCAGTATCTCACCTTCGACATTGCCCCTCACGGCATCGCGACCC
GGCGCTCCTACACGATAGCTTCGCCACCGAGCTGGCGTGACCGCATTGAGATTACAGTCAAACGAGAGCAATTCGGTCTG
GTATCGCGTTGGCTGCACGACGAAGTGGCCGTGGGCGACCTCATGAATATCGAGGCCCCCGGCGGCATGTTCGTGTTCTC
AGGTCGCGAGGGGCCGAGTGTGGTCCTTATCGGAGGCGGCGTCGGCATCACGCCAATGATGAGTATCGCTCGATACCTCA
CCGACACTCAGTGGCCTGGCACCATCTATCTGCTCACCAGCTTCCTACCCCGCAGGACATAA

Upstream 100 bases:

>100_bases
GACCCGAATCGCCTCACTTCACTCCAAGAAAGAATGAAGGCCGGTCCCCGTTTTGATCGGGAAGCCCGATTGTCAAAATG
GCAACCACTGAGGCAAGAGC

Downstream 100 bases:

>100_bases
TCTTCAGGCGGGAGATTGGGAGCCTGCGGAAGCGCAATCCCCGGCTGCGGGTCGCCACCACCGTCACCAACGCGCAAGGC
GACGACTGGACCGGTTCGAC

Product: 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 633; Mature: 633

Protein sequence:

>633_residues
MNLDDHPTVRQLRASGRLGETASIAGPIDANELRKLALECGAHDVGLVEIGRTELDPQRDEILKNYPWTRTLLSFVVKMV
REPVRGTPRSVSNLEFHRAGYETNEIAARIVSCLQDSGIRAVNPSMGFPMEMQNNPGAAIWIVSHKPVAVAAGLGRMGIH
RNLIHPKFGNFVLLGTVLLDQDVSAVDQSIDYNPCLECNLCVAVCPVGAIKPDGAFNFQACFTHNYREFMGGFNDWVEQI
ADAKDAIDYRKRVNEPETASMWQSLTYGANYKSAYCLAVCPAGEDVIGPYLNDKAAHRREIVRPLQERPETIYVVAGTDA
DQVARRKWKNKTVKPVGNGMTPRTISGLLTFMPIVFQPEQSRGLDAVFHFTFTGADHRDATITIKDRKITVREGLIGKAS
IRVTADAKTWLGFLAKEKNIVWALATRKIRISGDPRLLLAFGKCFPSPEIKRKHVEVIPEASLIVPAIRPFEKNDALTGK
ARWYGALLLKDIEQVTPNVKTFRFVNPKGGDIPFTHVAGQYLTFDIAPHGIATRRSYTIASPPSWRDRIEITVKREQFGL
VSRWLHDEVAVGDLMNIEAPGGMFVFSGREGPSVVLIGGGVGITPMMSIARYLTDTQWPGTIYLLTSFLPRRT

Sequences:

>Translated_633_residues
MNLDDHPTVRQLRASGRLGETASIAGPIDANELRKLALECGAHDVGLVEIGRTELDPQRDEILKNYPWTRTLLSFVVKMV
REPVRGTPRSVSNLEFHRAGYETNEIAARIVSCLQDSGIRAVNPSMGFPMEMQNNPGAAIWIVSHKPVAVAAGLGRMGIH
RNLIHPKFGNFVLLGTVLLDQDVSAVDQSIDYNPCLECNLCVAVCPVGAIKPDGAFNFQACFTHNYREFMGGFNDWVEQI
ADAKDAIDYRKRVNEPETASMWQSLTYGANYKSAYCLAVCPAGEDVIGPYLNDKAAHRREIVRPLQERPETIYVVAGTDA
DQVARRKWKNKTVKPVGNGMTPRTISGLLTFMPIVFQPEQSRGLDAVFHFTFTGADHRDATITIKDRKITVREGLIGKAS
IRVTADAKTWLGFLAKEKNIVWALATRKIRISGDPRLLLAFGKCFPSPEIKRKHVEVIPEASLIVPAIRPFEKNDALTGK
ARWYGALLLKDIEQVTPNVKTFRFVNPKGGDIPFTHVAGQYLTFDIAPHGIATRRSYTIASPPSWRDRIEITVKREQFGL
VSRWLHDEVAVGDLMNIEAPGGMFVFSGREGPSVVLIGGGVGITPMMSIARYLTDTQWPGTIYLLTSFLPRRT
>Mature_633_residues
MNLDDHPTVRQLRASGRLGETASIAGPIDANELRKLALECGAHDVGLVEIGRTELDPQRDEILKNYPWTRTLLSFVVKMV
REPVRGTPRSVSNLEFHRAGYETNEIAARIVSCLQDSGIRAVNPSMGFPMEMQNNPGAAIWIVSHKPVAVAAGLGRMGIH
RNLIHPKFGNFVLLGTVLLDQDVSAVDQSIDYNPCLECNLCVAVCPVGAIKPDGAFNFQACFTHNYREFMGGFNDWVEQI
ADAKDAIDYRKRVNEPETASMWQSLTYGANYKSAYCLAVCPAGEDVIGPYLNDKAAHRREIVRPLQERPETIYVVAGTDA
DQVARRKWKNKTVKPVGNGMTPRTISGLLTFMPIVFQPEQSRGLDAVFHFTFTGADHRDATITIKDRKITVREGLIGKAS
IRVTADAKTWLGFLAKEKNIVWALATRKIRISGDPRLLLAFGKCFPSPEIKRKHVEVIPEASLIVPAIRPFEKNDALTGK
ARWYGALLLKDIEQVTPNVKTFRFVNPKGGDIPFTHVAGQYLTFDIAPHGIATRRSYTIASPPSWRDRIEITVKREQFGL
VSRWLHDEVAVGDLMNIEAPGGMFVFSGREGPSVVLIGGGVGITPMMSIARYLTDTQWPGTIYLLTSFLPRRT

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=93, Percent_Identity=38.7096774193548, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 70233; Mature: 70233

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLDDHPTVRQLRASGRLGETASIAGPIDANELRKLALECGAHDVGLVEIGRTELDPQRD
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCHH
EILKNYPWTRTLLSFVVKMVREPVRGTPRSVSNLEFHRAGYETNEIAARIVSCLQDSGIR
HHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCE
AVNPSMGFPMEMQNNPGAAIWIVSHKPVAVAAGLGRMGIHRNLIHPKFGNFVLLGTVLLD
EECCCCCCCEEECCCCCEEEEEEECCCEEEECCCCCCCCHHCCCCCCCCCEEEEEEEHHC
QDVSAVDQSIDYNPCLECNLCVAVCPVGAIKPDGAFNFQACFTHNYREFMGGFNDWVEQI
CCHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEHEEECCHHHHHCCHHHHHHHH
ADAKDAIDYRKRVNEPETASMWQSLTYGANYKSAYCLAVCPAGEDVIGPYLNDKAAHRRE
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHH
IVRPLQERPETIYVVAGTDADQVARRKWKNKTVKPVGNGMTPRTISGLLTFMPIVFQPEQ
HHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCC
SRGLDAVFHFTFTGADHRDATITIKDRKITVREGLIGKASIRVTADAKTWLGFLAKEKNI
CCCCEEEEEEEEECCCCCCEEEEEECCEEEECCCCCCCEEEEEEECHHHHHHHHHCCCCE
VWALATRKIRISGDPRLLLAFGKCFPSPEIKRKHVEVIPEASLIVPAIRPFEKNDALTGK
EEEEEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCCCEEECCCCCCCCCCCCCCC
ARWYGALLLKDIEQVTPNVKTFRFVNPKGGDIPFTHVAGQYLTFDIAPHGIATRRSYTIA
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHCCCEEEEEECCCCCCCCCEEEEC
SPPSWRDRIEITVKREQFGLVSRWLHDEVAVGDLMNIEAPGGMFVFSGREGPSVVLIGGG
CCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEECCCCCEEEEECCC
VGITPMMSIARYLTDTQWPGTIYLLTSFLPRRT
CCHHHHHHHHHHHCCCCCCCEEEEHHHHCCCCC
>Mature Secondary Structure
MNLDDHPTVRQLRASGRLGETASIAGPIDANELRKLALECGAHDVGLVEIGRTELDPQRD
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCHH
EILKNYPWTRTLLSFVVKMVREPVRGTPRSVSNLEFHRAGYETNEIAARIVSCLQDSGIR
HHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCE
AVNPSMGFPMEMQNNPGAAIWIVSHKPVAVAAGLGRMGIHRNLIHPKFGNFVLLGTVLLD
EECCCCCCCEEECCCCCEEEEEEECCCEEEECCCCCCCCHHCCCCCCCCCEEEEEEEHHC
QDVSAVDQSIDYNPCLECNLCVAVCPVGAIKPDGAFNFQACFTHNYREFMGGFNDWVEQI
CCHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEHEEECCHHHHHCCHHHHHHHH
ADAKDAIDYRKRVNEPETASMWQSLTYGANYKSAYCLAVCPAGEDVIGPYLNDKAAHRRE
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHH
IVRPLQERPETIYVVAGTDADQVARRKWKNKTVKPVGNGMTPRTISGLLTFMPIVFQPEQ
HHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCC
SRGLDAVFHFTFTGADHRDATITIKDRKITVREGLIGKASIRVTADAKTWLGFLAKEKNI
CCCCEEEEEEEEECCCCCCEEEEEECCEEEECCCCCCCEEEEEEECHHHHHHHHHCCCCE
VWALATRKIRISGDPRLLLAFGKCFPSPEIKRKHVEVIPEASLIVPAIRPFEKNDALTGK
EEEEEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCCCEEECCCCCCCCCCCCCCC
ARWYGALLLKDIEQVTPNVKTFRFVNPKGGDIPFTHVAGQYLTFDIAPHGIATRRSYTIA
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHCCCEEEEEECCCCCCCCCEEEEC
SPPSWRDRIEITVKREQFGLVSRWLHDEVAVGDLMNIEAPGGMFVFSGREGPSVVLIGGG
CCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEECCCCCEEEEECCC
VGITPMMSIARYLTDTQWPGTIYLLTSFLPRRT
CCHHHHHHHHHHHCCCCCCCEEEEHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA