Click here to switch to the map view.

The map label for this gene is mdtA [H]

Identifier: 158422903

GI number: 158422903

Start: 1432828

End: 1434006

Strand: Reverse

Name: mdtA [H]

Synonym: AZC_1279

Alternate gene names: 158422903

Gene position: 1434006-1432828 (Counterclockwise)

Preceding gene: 158422910

Following gene: 158422902

Centisome position: 26.71

GC content: 65.73

Gene sequence:

>1179_bases
TTGCGTTCGGCATCTATATCCAATATAGCGTTCGGACGCAATCTAATTTGGCAGGCGACGGCTATGAAAAAGCCCATTCT
CCTCGTGGCAGGCGTTGTGACCGCAGTGGCTGGGGCGGCCGGCTTTTTCGCGCTTTCCCCTTCTTCACCACATGCCGGAC
CGATTGGTGATCCCAGGGAGGAGGCACCGCTTGTAAGGGTGATGAAGATCGCGCCGACAGCGGGCCTCGAGCGAGGCTTT
ACGGGTCTCATAGAGGCGCGGGTCCAGAGCAATGTCGGCTTCCGCGTGCCCGGCAAGATCGTCGAGCGGCTCGTCGATGT
CGGGCAGCAGGTCAAGGCGGGCCAGCCCCTTATGCGGATCGACGACACGGATCTGCGCCTCGCGCTGACCGCCAAGCGCA
ACGCCGTGGCGGCTGCCCGCGCGGTGCTGGTTCAGGCGAGCGCCGACGAAAAGCGATACGCCGCGCTGGTGAAGGGCGGG
CTTGCTGCAACGCCGCAACGCTACGAACAGGCCAAGGCCGCGCTCGACACGGCTCAGGCGCAGCTCGATGTTGCGGAAGC
GGAAGCCGATGTCGCCGCAAACGAAGCGACCTATTCCACGTTAACCGCAGGAGCCGACGGCACCATCGTCGCCACCCTTG
GCGAACCCGGACAGGTGGTCGCGGCGGGCCAAACGGTCATTCAGCTGGCCCAAGCTGGGCCGCGCGAAGCTGTCGTAGCA
CTGCCCGAGACGATCCGCCCCGCCTTGGGCTCGCAGGCCAAGGCGCGCGTCTATGGCAGTGATGCCGAACCCAGCTCGGC
GCGACTGCGGCAGATCTCCGATGCGGCCGACTCCCAGACGCGCACCTATGAGGCGCGGTACGTCCTTGAGGGGCCCGCCG
CCGCGGCCCCTCTTGGAACGACCGTAACGATCACCATCCCCAGCGGGGAGGCCCAACCCTCTGTGAGCGTCCCCATCGGC
GCCGTGCTGAATGATGGCGTGCGGACCGGCGTATGGGTTCTCGACCCGACCTCATCCACGGTCCGCTTCGTGCCCGTCCA
AGTCAAACGCCTCGGAAACGAATACGCGACGGTCACCGGCGTCGCACTTGGCGCGGACGTCGTGGCGCTCGGCGCGCATC
TCCTGAAAGACGGCGCCGCCGTACGGACGGCGAAGCTGATTGAGGGGAATTCCAAATGA

Upstream 100 bases:

>100_bases
CGTGCTCGCGAAAGAGACGGCTCGCCACACTGATCACCGTTTGCCGGTTTTCTTCCGCCTGAATTCGACTGACGCGCATA
ACTGACCTCCCGAATTTAGA

Downstream 100 bases:

>100_bases
GCTTCAATCTCTCAGCGCTGGCAGTCCGTGAGCGTGCCGTCACCCTCTTCTTCATCGTGCTGCTGGCGGCCGCGGGCGTC
TATGCCTTCGTCAAGCTTGG

Product: component of multidrug efflux system protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MRSASISNIAFGRNLIWQATAMKKPILLVAGVVTAVAGAAGFFALSPSSPHAGPIGDPREEAPLVRVMKIAPTAGLERGF
TGLIEARVQSNVGFRVPGKIVERLVDVGQQVKAGQPLMRIDDTDLRLALTAKRNAVAAARAVLVQASADEKRYAALVKGG
LAATPQRYEQAKAALDTAQAQLDVAEAEADVAANEATYSTLTAGADGTIVATLGEPGQVVAAGQTVIQLAQAGPREAVVA
LPETIRPALGSQAKARVYGSDAEPSSARLRQISDAADSQTRTYEARYVLEGPAAAAPLGTTVTITIPSGEAQPSVSVPIG
AVLNDGVRTGVWVLDPTSSTVRFVPVQVKRLGNEYATVTGVALGADVVALGAHLLKDGAAVRTAKLIEGNSK

Sequences:

>Translated_392_residues
MRSASISNIAFGRNLIWQATAMKKPILLVAGVVTAVAGAAGFFALSPSSPHAGPIGDPREEAPLVRVMKIAPTAGLERGF
TGLIEARVQSNVGFRVPGKIVERLVDVGQQVKAGQPLMRIDDTDLRLALTAKRNAVAAARAVLVQASADEKRYAALVKGG
LAATPQRYEQAKAALDTAQAQLDVAEAEADVAANEATYSTLTAGADGTIVATLGEPGQVVAAGQTVIQLAQAGPREAVVA
LPETIRPALGSQAKARVYGSDAEPSSARLRQISDAADSQTRTYEARYVLEGPAAAAPLGTTVTITIPSGEAQPSVSVPIG
AVLNDGVRTGVWVLDPTSSTVRFVPVQVKRLGNEYATVTGVALGADVVALGAHLLKDGAAVRTAKLIEGNSK
>Mature_392_residues
MRSASISNIAFGRNLIWQATAMKKPILLVAGVVTAVAGAAGFFALSPSSPHAGPIGDPREEAPLVRVMKIAPTAGLERGF
TGLIEARVQSNVGFRVPGKIVERLVDVGQQVKAGQPLMRIDDTDLRLALTAKRNAVAAARAVLVQASADEKRYAALVKGG
LAATPQRYEQAKAALDTAQAQLDVAEAEADVAANEATYSTLTAGADGTIVATLGEPGQVVAAGQTVIQLAQAGPREAVVA
LPETIRPALGSQAKARVYGSDAEPSSARLRQISDAADSQTRTYEARYVLEGPAAAAPLGTTVTITIPSGEAQPSVSVPIG
AVLNDGVRTGVWVLDPTSSTVRFVPVQVKRLGNEYATVTGVALGADVVALGAHLLKDGAAVRTAKLIEGNSK

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40330; Mature: 40330

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSASISNIAFGRNLIWQATAMKKPILLVAGVVTAVAGAAGFFALSPSSPHAGPIGDPRE
CCCCCCCHHCCCCCCEEEHHHHCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCC
EAPLVRVMKIAPTAGLERGFTGLIEARVQSNVGFRVPGKIVERLVDVGQQVKAGQPLMRI
CCCCEEEEEECCCCCHHCCHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHCCCCCEEE
DDTDLRLALTAKRNAVAAARAVLVQASADEKRYAALVKGGLAATPQRYEQAKAALDTAQA
CCCCEEEEEEECCCHHHHHHHHEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
QLDVAEAEADVAANEATYSTLTAGADGTIVATLGEPGQVVAAGQTVIQLAQAGPREAVVA
HHHHHHHHHHHHCCCCHHEEEECCCCCEEEEEECCCCCEEECCHHHHHHHHCCCCCEEEE
LPETIRPALGSQAKARVYGSDAEPSSARLRQISDAADSQTRTYEARYVLEGPAAAAPLGT
CCHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCC
TVTITIPSGEAQPSVSVPIGAVLNDGVRTGVWVLDPTSSTVRFVPVQVKRLGNEYATVTG
EEEEEECCCCCCCCCCCCHHHHHCCCCCCCEEEECCCCCCEEEEEHHHHHCCCCCEEEEE
VALGADVVALGAHLLKDGAAVRTAKLIEGNSK
HHHHHHHHHHHHHHHHCCCHHEEEEEECCCCC
>Mature Secondary Structure
MRSASISNIAFGRNLIWQATAMKKPILLVAGVVTAVAGAAGFFALSPSSPHAGPIGDPRE
CCCCCCCHHCCCCCCEEEHHHHCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCC
EAPLVRVMKIAPTAGLERGFTGLIEARVQSNVGFRVPGKIVERLVDVGQQVKAGQPLMRI
CCCCEEEEEECCCCCHHCCHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHCCCCCEEE
DDTDLRLALTAKRNAVAAARAVLVQASADEKRYAALVKGGLAATPQRYEQAKAALDTAQA
CCCCEEEEEEECCCHHHHHHHHEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
QLDVAEAEADVAANEATYSTLTAGADGTIVATLGEPGQVVAAGQTVIQLAQAGPREAVVA
HHHHHHHHHHHHCCCCHHEEEECCCCCEEEEEECCCCCEEECCHHHHHHHHCCCCCEEEE
LPETIRPALGSQAKARVYGSDAEPSSARLRQISDAADSQTRTYEARYVLEGPAAAAPLGT
CCHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCC
TVTITIPSGEAQPSVSVPIGAVLNDGVRTGVWVLDPTSSTVRFVPVQVKRLGNEYATVTG
EEEEEECCCCCCCCCCCCHHHHHCCCCCCCEEEECCCCCCEEEEEHHHHHCCCCCEEEEE
VALGADVVALGAHLLKDGAAVRTAKLIEGNSK
HHHHHHHHHHHHHHHHCCCHHEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]