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The map label for this gene is lrp [H]

Identifier: 158422771

GI number: 158422771

Start: 1279923

End: 1280408

Strand: Reverse

Name: lrp [H]

Synonym: AZC_1147

Alternate gene names: 158422771

Gene position: 1280408-1279923 (Counterclockwise)

Preceding gene: 158422775

Following gene: 158422768

Centisome position: 23.84

GC content: 65.43

Gene sequence:

>486_bases
TTGACCGTTCGTCTCGATGCCGTGGACTGGAAGATCCTGGCCGAGCTGCAACGGGACGGCCGCATGACCAACGTGGAGCT
GTCGCGCCGCGTCGGCATTTCCGCTCCGCCCTGCCTGCGCCGCGTCCGCAGCCTCGAGGAAGACGGAATCATCAAGGGTT
ACCGGGCGCTGCTGGACGAGAAGCAGCTCGGCTACGACCTCATGGCCTTTGCCATGGTGCATCTCATCAGCCAGGCGGGG
TCCGACCTTGCTGCCTTCGAGGCGCGGATCGAACACTGGCCACTGGTGCGCGCCTCCTGGATGCTCTCGGGCGACGTGGA
CTTCCTGATGCTCTGCGTCGCGCCCGACCTGCCGACCTTCCAGAAATTCGTGCTGGAGATCACCTCCGCGCCCAACGTGC
GCAATGTGAAGACGGCGCTGACGCTGAAGCAGTCCAAGAACGCGCCCATCGTGCCCTTGGAAGAGGGCTCCCCGCCCCCG
GAGTGA

Upstream 100 bases:

>100_bases
CATCGAATCGGTGCACCGCGGCGTCGCGCAATATTATTTCGTTGCGCTGCGTCTAGGCTTCACTAAGGTGCCTGACGAAA
TCGCCCCGGAGGATTCCCCC

Downstream 100 bases:

>100_bases
GCGGACCGCCGAGACCGGTCGCCGTTGCGACGTAAAGTCCCGGCAAAACAGACGTTTCGTACGCCTCGGCCCACGCAAAA
AGGGCGCCGGAGGCCCCGCG

Product: transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MTVRLDAVDWKILAELQRDGRMTNVELSRRVGISAPPCLRRVRSLEEDGIIKGYRALLDEKQLGYDLMAFAMVHLISQAG
SDLAAFEARIEHWPLVRASWMLSGDVDFLMLCVAPDLPTFQKFVLEITSAPNVRNVKTALTLKQSKNAPIVPLEEGSPPP
E

Sequences:

>Translated_161_residues
MTVRLDAVDWKILAELQRDGRMTNVELSRRVGISAPPCLRRVRSLEEDGIIKGYRALLDEKQLGYDLMAFAMVHLISQAG
SDLAAFEARIEHWPLVRASWMLSGDVDFLMLCVAPDLPTFQKFVLEITSAPNVRNVKTALTLKQSKNAPIVPLEEGSPPP
E
>Mature_160_residues
TVRLDAVDWKILAELQRDGRMTNVELSRRVGISAPPCLRRVRSLEEDGIIKGYRALLDEKQLGYDLMAFAMVHLISQAGS
DLAAFEARIEHWPLVRASWMLSGDVDFLMLCVAPDLPTFQKFVLEITSAPNVRNVKTALTLKQSKNAPIVPLEEGSPPPE

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=145, Percent_Identity=37.2413793103448, Blast_Score=105, Evalue=1e-24,
Organism=Escherichia coli, GI87081742, Length=151, Percent_Identity=29.8013245033113, Blast_Score=86, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17985; Mature: 17854

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRLDAVDWKILAELQRDGRMTNVELSRRVGISAPPCLRRVRSLEEDGIIKGYRALLDE
CEEEECCHHHHHHHHHHHCCCCCCEEHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHH
KQLGYDLMAFAMVHLISQAGSDLAAFEARIEHWPLVRASWMLSGDVDFLMLCVAPDLPTF
HHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEECCCHHEEEEEECCCCCHH
QKFVLEITSAPNVRNVKTALTLKQSKNAPIVPLEEGSPPPE
HHHHHHHCCCCCCCCHHHHEEEECCCCCCEEECCCCCCCCC
>Mature Secondary Structure 
TVRLDAVDWKILAELQRDGRMTNVELSRRVGISAPPCLRRVRSLEEDGIIKGYRALLDE
EEEECCHHHHHHHHHHHCCCCCCEEHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHH
KQLGYDLMAFAMVHLISQAGSDLAAFEARIEHWPLVRASWMLSGDVDFLMLCVAPDLPTF
HHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEECCCHHEEEEEECCCCCHH
QKFVLEITSAPNVRNVKTALTLKQSKNAPIVPLEEGSPPPE
HHHHHHHCCCCCCCCHHHHEEEECCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157937; 11481430 [H]