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The map label for this gene is cycJ

Identifier: 158422757

GI number: 158422757

Start: 1259643

End: 1260167

Strand: Direct

Name: cycJ

Synonym: AZC_1133

Alternate gene names: 158422757

Gene position: 1259643-1260167 (Clockwise)

Preceding gene: 158422756

Following gene: 158422758

Centisome position: 23.46

GC content: 70.86

Gene sequence:

>525_bases
GTGACCCGTAAAAGCCGCCGCCTCATTCTCATCGGCGCGGGCCTCGGCGTGCTCGCGCTCGCTGCCGGCCTGATCCTGAC
CGCCCTCAACGACACCATCGTCTTCTTCCGCACGCCCACGGAAGTGGCGCAGCAGCAGATCGCGCCCGGCGCCCGCCTGC
GCCTCGGCGGCCTTGTGGAGCCGGGCAGCGTCGCCAAGAGCGGTGCGTCCGTGCGCTTTGCGGTGACGGACGGCAATTCC
AAGGTCACGGTGGCTTACACGGGCCTCCTGCCGGACCTGTTCCGGGAAGGGCAGGGCGTGGTGGCCGAAGGCGTGCTCCA
GAGCGACGGCACCGTGAAGGCCGATAGCGTGCTCGCAAAGCATGACGAGCGCTACATGCCCCGCGAGGTGGCCGACGCAC
TGAAGAAGTCCGGCCACTGGAAGGAAGGCGAGGAGGGCGGCCCCGTGCCGCCAGCCGCCAAGACGCCCGGTCCCCAGTCC
TCCGCCGCCCCGCCCGCCGTCTCTCCTGCCCGGAGCACCCCATGA

Upstream 100 bases:

>100_bases
GAACTGGGGCTCGGGGGTTAGGCTGCAACCAGCCGATGCAGGTCAAGGATCGGGCTGGAGAACTGCTGTATGAGGGCTGG
AGCTTGGAGACGTTAAGACC

Downstream 100 bases:

>100_bases
TCGCGGAACTCGGCCATTACGCCCTCGTCCTCGCGCTCGCTCTGTCGCTGGTGCAGATGGTGGTGCCGGCCTGGGGCGCG
GCGAAGCAGGACCCGGTTCT

Product: cytochrome c-type biogenesis protein

Products: NA

Alternate protein names: Cytochrome c maturation protein E; Heme chaperone CcmE

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MTRKSRRLILIGAGLGVLALAAGLILTALNDTIVFFRTPTEVAQQQIAPGARLRLGGLVEPGSVAKSGASVRFAVTDGNS
KVTVAYTGLLPDLFREGQGVVAEGVLQSDGTVKADSVLAKHDERYMPREVADALKKSGHWKEGEEGGPVPPAAKTPGPQS
SAAPPAVSPARSTP

Sequences:

>Translated_174_residues
MTRKSRRLILIGAGLGVLALAAGLILTALNDTIVFFRTPTEVAQQQIAPGARLRLGGLVEPGSVAKSGASVRFAVTDGNS
KVTVAYTGLLPDLFREGQGVVAEGVLQSDGTVKADSVLAKHDERYMPREVADALKKSGHWKEGEEGGPVPPAAKTPGPQS
SAAPPAVSPARSTP
>Mature_173_residues
TRKSRRLILIGAGLGVLALAAGLILTALNDTIVFFRTPTEVAQQQIAPGARLRLGGLVEPGSVAKSGASVRFAVTDGNSK
VTVAYTGLLPDLFREGQGVVAEGVLQSDGTVKADSVLAKHDERYMPREVADALKKSGHWKEGEEGGPVPPAAKTPGPQSS
AAPPAVSPARSTP

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family

Homologues:

Organism=Escherichia coli, GI1788525, Length=141, Percent_Identity=46.0992907801418, Blast_Score=114, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCME_AZOC5 (A8HR72)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001524049.1
- ProteinModelPortal:   A8HR72
- SMR:   A8HR72
- GeneID:   5690226
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_1133
- HOGENOM:   HBG296631
- OMA:   HVEFAVH
- ProtClustDB:   CLSK979477
- BioCyc:   ACAU438753:AZC_1133-MONOMER
- HAMAP:   MF_01959
- InterPro:   IPR004329
- InterPro:   IPR012340
- Gene3D:   G3DSA:2.40.50.140

Pfam domain/function: PF03100 CcmE; SSF82093 Pyrv/PenolPyrv_Kinase_cat

EC number: NA

Molecular weight: Translated: 17960; Mature: 17829

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: BINDING 121-121

Signals:

None

Transmembrane regions:

HASH(0x1c244628)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKSRRLILIGAGLGVLALAAGLILTALNDTIVFFRTPTEVAQQQIAPGARLRLGGLVE
CCCCCCEEEEEECCHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHCCCCCEEEECCCCC
PGSVAKSGASVRFAVTDGNSKVTVAYTGLLPDLFREGQGVVAEGVLQSDGTVKADSVLAK
CCCCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHCCCCCEECCEECCCCCCCHHHHHHH
HDERYMPREVADALKKSGHWKEGEEGGPVPPAAKTPGPQSSAAPPAVSPARSTP
HCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure 
TRKSRRLILIGAGLGVLALAAGLILTALNDTIVFFRTPTEVAQQQIAPGARLRLGGLVE
CCCCCEEEEEECCHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHCCCCCEEEECCCCC
PGSVAKSGASVRFAVTDGNSKVTVAYTGLLPDLFREGQGVVAEGVLQSDGTVKADSVLAK
CCCCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHCCCCCEECCEECCCCCCCHHHHHHH
HDERYMPREVADALKKSGHWKEGEEGGPVPPAAKTPGPQSSAAPPAVSPARSTP
HCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA