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The map label for this gene is gltS [H]

Identifier: 158422698

GI number: 158422698

Start: 1200352

End: 1201650

Strand: Direct

Name: gltS [H]

Synonym: AZC_1074

Alternate gene names: 158422698

Gene position: 1200352-1201650 (Clockwise)

Preceding gene: 158422697

Following gene: 158422699

Centisome position: 22.35

GC content: 67.98

Gene sequence:

>1299_bases
GTGGGGCCGGCAGGAACGCTTTCGGCAGCGCCGGCGCTTTATCCCCGTGGCGGTTCGGGCGATAAGAAGGCTCCGGTGCC
ACGGAGAGCAGGGCGGATGAGCTATCAAGTTCCCGGCTTCATCGCCTTCACCATCGCCATCGTGGTCTATTTCGTCGGTG
CCGGGCTCAACAACCTCGTCCCGCCGCTGCGCCGCTGGAACATTCCGGAGGCAGTGACCGGTGGACTGCTTGCGGCACTG
GCGACCCTTGTGGCGCACAACGGCTTCGGCCTCGCCATCTCCTTCGACATTGCGGCCCGCGACCTGCTGCTGCTCTATTT
CTTCACCGGCATCGGCCTCAATGCGCGCCTTGCCGATCTTGGCGCCGGCGGGCGGCCGCTGGTCATCCTGCTCGTCCTCA
CTGTCGTCTATCTCGGTCTCCAGAATGCCGTGGCGCTGGGCGCTGCGGCGGCGCTGAAGCTACCGGAGGGCATGGCGCCG
CTGCTCGGCTCGGTGTCACTGGTGGGCGGGCACGGCACCACCATCGCCTGGGCGCCCCTCATCTCGCAGCGCTTCGGCCT
CAGCAACGCGCTGGAGGTGGGGATCGCGAGCGCTACCCTCGGCCTCGTTCTCGCGAGCCTGCTCGGCGGCCCCATCGCCG
GCCTGCTGATCTCGCGCTTCCGGCTGCGTGGCGGGGCTGCGGAGGCGCCCATGGTCGGCCTGCCCGAGGAGACGGGCCAG
CCGGAGGGCGGGGAGGTGGGCTATCGCAACATCCTGAGCACGCTGCTGGTGCTCAATGTTGTGATCCTGGTCGCCTATTC
GCTGGAGGGAATCGTCGAGAAGACCGGCATCAAGCTGCCGCTGTTCGTGGTGTGCCTACTGGTGGCGATCGTGGTCACGA
ACCTCCTGCCGCTGGTGTTGCCGCGCCTGCCGTGGCCGGCGCGCACGCCGGCGCTGGCGCTGATCTCGGACCTGTCGCTG
AAGATCTTCCTCGCCATGTCGCTCATGAGCATGCAGCTCTGGACCCTGGGCGGACTTGGTCCGGCCCTGGCTCTGGTGCT
GGGGCTGCAGAGCCTCGTCGCCGTGCTCTACATCCTGTTCGTGGTGTTTCCGGCCATGGGGCGGACCTATCAGGCCGCCG
TGCTGGCGGCGGGCTTCACCGGCATCAGCCTCGGGGCCACGCCCACCGCCATCGCCAACATGACGGCGGTCACGCGCACC
CACGGCCCGGCGCCGCTGGCCTTCATCATCCTGCCGCTGGTCTCGGCCTTCTTCATCGACATCATCAACGCGATCGCCAT
CGGCTTCATGGTGCGCTGA

Upstream 100 bases:

>100_bases
CTCGGCGAGCGCCTCTCGCTGCCGCCCTTCCTCGAAGGCCGCCGCCGAGAGATCGAGGCGGGCCTGAAGCCGCTCTGAGC
ACCTTCCTGCCGGCCTCTCC

Downstream 100 bases:

>100_bases
GCGCATCGGGGTCGGGGCGGCGCCCCGCAGGGATTGGTTGCATCGTAATAATTAGGGTGCTAATAGAAAGCATGACTTAT
AAATATTCCGCGCCCACGCT

Product: sodium/glutamate symporter

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MGPAGTLSAAPALYPRGGSGDKKAPVPRRAGRMSYQVPGFIAFTIAIVVYFVGAGLNNLVPPLRRWNIPEAVTGGLLAAL
ATLVAHNGFGLAISFDIAARDLLLLYFFTGIGLNARLADLGAGGRPLVILLVLTVVYLGLQNAVALGAAAALKLPEGMAP
LLGSVSLVGGHGTTIAWAPLISQRFGLSNALEVGIASATLGLVLASLLGGPIAGLLISRFRLRGGAAEAPMVGLPEETGQ
PEGGEVGYRNILSTLLVLNVVILVAYSLEGIVEKTGIKLPLFVVCLLVAIVVTNLLPLVLPRLPWPARTPALALISDLSL
KIFLAMSLMSMQLWTLGGLGPALALVLGLQSLVAVLYILFVVFPAMGRTYQAAVLAAGFTGISLGATPTAIANMTAVTRT
HGPAPLAFIILPLVSAFFIDIINAIAIGFMVR

Sequences:

>Translated_432_residues
MGPAGTLSAAPALYPRGGSGDKKAPVPRRAGRMSYQVPGFIAFTIAIVVYFVGAGLNNLVPPLRRWNIPEAVTGGLLAAL
ATLVAHNGFGLAISFDIAARDLLLLYFFTGIGLNARLADLGAGGRPLVILLVLTVVYLGLQNAVALGAAAALKLPEGMAP
LLGSVSLVGGHGTTIAWAPLISQRFGLSNALEVGIASATLGLVLASLLGGPIAGLLISRFRLRGGAAEAPMVGLPEETGQ
PEGGEVGYRNILSTLLVLNVVILVAYSLEGIVEKTGIKLPLFVVCLLVAIVVTNLLPLVLPRLPWPARTPALALISDLSL
KIFLAMSLMSMQLWTLGGLGPALALVLGLQSLVAVLYILFVVFPAMGRTYQAAVLAAGFTGISLGATPTAIANMTAVTRT
HGPAPLAFIILPLVSAFFIDIINAIAIGFMVR
>Mature_431_residues
GPAGTLSAAPALYPRGGSGDKKAPVPRRAGRMSYQVPGFIAFTIAIVVYFVGAGLNNLVPPLRRWNIPEAVTGGLLAALA
TLVAHNGFGLAISFDIAARDLLLLYFFTGIGLNARLADLGAGGRPLVILLVLTVVYLGLQNAVALGAAAALKLPEGMAPL
LGSVSLVGGHGTTIAWAPLISQRFGLSNALEVGIASATLGLVLASLLGGPIAGLLISRFRLRGGAAEAPMVGLPEETGQP
EGGEVGYRNILSTLLVLNVVILVAYSLEGIVEKTGIKLPLFVVCLLVAIVVTNLLPLVLPRLPWPARTPALALISDLSLK
IFLAMSLMSMQLWTLGGLGPALALVLGLQSLVAVLYILFVVFPAMGRTYQAAVLAAGFTGISLGATPTAIANMTAVTRTH
GPAPLAFIILPLVSAFFIDIINAIAIGFMVR

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=389, Percent_Identity=41.6452442159383, Blast_Score=224, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 44566; Mature: 44435

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPAGTLSAAPALYPRGGSGDKKAPVPRRAGRMSYQVPGFIAFTIAIVVYFVGAGLNNLV
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHCC
PPLRRWNIPEAVTGGLLAALATLVAHNGFGLAISFDIAARDLLLLYFFTGIGLNARLADL
CCHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCHHHC
GAGGRPLVILLVLTVVYLGLQNAVALGAAAALKLPEGMAPLLGSVSLVGGHGTTIAWAPL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCEEEECCCCCEEHHHHH
ISQRFGLSNALEVGIASATLGLVLASLLGGPIAGLLISRFRLRGGAAEAPMVGLPEETGQ
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCHHCCC
PEGGEVGYRNILSTLLVLNVVILVAYSLEGIVEKTGIKLPLFVVCLLVAIVVTNLLPLVL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
PRLPWPARTPALALISDLSLKIFLAMSLMSMQLWTLGGLGPALALVLGLQSLVAVLYILF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VVFPAMGRTYQAAVLAAGFTGISLGATPTAIANMTAVTRTHGPAPLAFIILPLVSAFFID
HHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
IINAIAIGFMVR
HHHHHHHHHHCC
>Mature Secondary Structure 
GPAGTLSAAPALYPRGGSGDKKAPVPRRAGRMSYQVPGFIAFTIAIVVYFVGAGLNNLV
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHCC
PPLRRWNIPEAVTGGLLAALATLVAHNGFGLAISFDIAARDLLLLYFFTGIGLNARLADL
CCHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCHHHC
GAGGRPLVILLVLTVVYLGLQNAVALGAAAALKLPEGMAPLLGSVSLVGGHGTTIAWAPL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCEEEECCCCCEEHHHHH
ISQRFGLSNALEVGIASATLGLVLASLLGGPIAGLLISRFRLRGGAAEAPMVGLPEETGQ
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCHHCCC
PEGGEVGYRNILSTLLVLNVVILVAYSLEGIVEKTGIKLPLFVVCLLVAIVVTNLLPLVL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
PRLPWPARTPALALISDLSLKIFLAMSLMSMQLWTLGGLGPALALVLGLQSLVAVLYILF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VVFPAMGRTYQAAVLAAGFTGISLGATPTAIANMTAVTRTHGPAPLAFIILPLVSAFFID
HHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
IINAIAIGFMVR
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]