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The map label for this gene is htxC [H]

Identifier: 158422679

GI number: 158422679

Start: 1183852

End: 1184727

Strand: Reverse

Name: htxC [H]

Synonym: AZC_1055

Alternate gene names: 158422679

Gene position: 1184727-1183852 (Counterclockwise)

Preceding gene: 158422680

Following gene: 158422678

Centisome position: 22.06

GC content: 67.92

Gene sequence:

>876_bases
GTGACCGCCACCTCCCCCACCGCGCCGCGCCCGGTGCTTGAAACCGATGTCGCGGCCATGCGCGCGCGCTATCCGGACGC
CTTCCGAGCCCATCCCGCGCGGCGACTGAAGACGGCAGCCTTCATCGGCATCATCGTCGGCATCGCGCTCTTCGCGCTCT
GGGCGCTGGACTTCTCGCCCCAGCGCATCTGGCAGGGGCTGAGCCGCCTCGGCCTCTTCTTCTCGCTGCTGTTCCCGCCC
GATGCGCACGGCCGCCTGCCGGCCTTCATGAAGGCGCTTGGCGAGACGCTGGCCATCGCCTTCCTGGGCACCCTCACCGC
CGCCCTCGTCGCCTTCCCGGTGGCCTTCCTCGCGGCCAAGAACGTGGTGCCGAACATCTTCGTCCACTTCTCGCTGCGTC
GGGTGTTCGATGTCTCGCGCTCGGTGGACACGCTCATCTGGGCACTCATGTGGATCAATGTGGTGGGTCTCGGCCCCTTC
GCCGGCGCGCTCGCCATCGCCTGCGCGGATTTCGGCGCCTTCGGCAAGCTGTTCTCGGAGGCCATCGAGGCGGCGGACCG
CAAACCGGTGGAGGGCGTGCTCGCCTCGGGCGGCAGCGGGCTCCACCGCGTGCGCTTCGCGCTGGTGCCGCAGATCCTGC
CGGTGATCGCCAGCCAGATCCTCTATTTCTTCGAATCCAACACCCGCTCGGCCACCATCATCGGCATCGTCGGGGCGGGC
GGCATCGGCGGCTATCTCACGGAGCTGATCCGCACGCTGGAAATGAGCCAGGTGTGCGTGATCATCATCATGATCCTGAT
CACCGTGGCGGTGATCGACTTCGTGTCCTCGCGCCTGCGCTTCGCCATCATCGGCCGCAAGCCCGCCAGCGCTTGA

Upstream 100 bases:

>100_bases
ACGTAAGCGCCATCCTGCTGATGATCATCGCCACGGTGATCCTCATCGACCTTGGCACCGAGCGCATCCGCCACCGCCTG
CTCTTTCAGGATCAGCGCCA

Downstream 100 bases:

>100_bases
TAAGGACGGCACTGGCTGGCCGCGCGACACTTTGGCGGCTGCCTCCTATTCCCCGCTGAATATATCTTTCCCCCAAACAG
GGGGCAGCGATGAAGATCAG

Product: phosphonate uptake transporter

Products: 3-phospho-serine [Cytoplasm]; phosphite [Cytoplasm]; ADP; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MTATSPTAPRPVLETDVAAMRARYPDAFRAHPARRLKTAAFIGIIVGIALFALWALDFSPQRIWQGLSRLGLFFSLLFPP
DAHGRLPAFMKALGETLAIAFLGTLTAALVAFPVAFLAAKNVVPNIFVHFSLRRVFDVSRSVDTLIWALMWINVVGLGPF
AGALAIACADFGAFGKLFSEAIEAADRKPVEGVLASGGSGLHRVRFALVPQILPVIASQILYFFESNTRSATIIGIVGAG
GIGGYLTELIRTLEMSQVCVIIIMILITVAVIDFVSSRLRFAIIGRKPASA

Sequences:

>Translated_291_residues
MTATSPTAPRPVLETDVAAMRARYPDAFRAHPARRLKTAAFIGIIVGIALFALWALDFSPQRIWQGLSRLGLFFSLLFPP
DAHGRLPAFMKALGETLAIAFLGTLTAALVAFPVAFLAAKNVVPNIFVHFSLRRVFDVSRSVDTLIWALMWINVVGLGPF
AGALAIACADFGAFGKLFSEAIEAADRKPVEGVLASGGSGLHRVRFALVPQILPVIASQILYFFESNTRSATIIGIVGAG
GIGGYLTELIRTLEMSQVCVIIIMILITVAVIDFVSSRLRFAIIGRKPASA
>Mature_290_residues
TATSPTAPRPVLETDVAAMRARYPDAFRAHPARRLKTAAFIGIIVGIALFALWALDFSPQRIWQGLSRLGLFFSLLFPPD
AHGRLPAFMKALGETLAIAFLGTLTAALVAFPVAFLAAKNVVPNIFVHFSLRRVFDVSRSVDTLIWALMWINVVGLGPFA
GALAIACADFGAFGKLFSEAIEAADRKPVEGVLASGGSGLHRVRFALVPQILPVIASQILYFFESNTRSATIIGIVGAGG
IGGYLTELIRTLEMSQVCVIIIMILITVAVIDFVSSRLRFAIIGRKPASA

Specific function: Probably forms part of a binding-protein-dependent hypophosphite transporter [H]

COG id: COG3639

COG function: function code P; ABC-type phosphate/phosphonate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR005769 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31225; Mature: 31094

Theoretical pI: Translated: 10.82; Mature: 10.82

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATSPTAPRPVLETDVAAMRARYPDAFRAHPARRLKTAAFIGIIVGIALFALWALDFSP
CCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
QRIWQGLSRLGLFFSLLFPPDAHGRLPAFMKALGETLAIAFLGTLTAALVAFPVAFLAAK
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVVPNIFVHFSLRRVFDVSRSVDTLIWALMWINVVGLGPFAGALAIACADFGAFGKLFSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AIEAADRKPVEGVLASGGSGLHRVRFALVPQILPVIASQILYFFESNTRSATIIGIVGAG
HHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
GIGGYLTELIRTLEMSQVCVIIIMILITVAVIDFVSSRLRFAIIGRKPASA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCC
>Mature Secondary Structure 
TATSPTAPRPVLETDVAAMRARYPDAFRAHPARRLKTAAFIGIIVGIALFALWALDFSP
CCCCCCCCCCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
QRIWQGLSRLGLFFSLLFPPDAHGRLPAFMKALGETLAIAFLGTLTAALVAFPVAFLAAK
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVVPNIFVHFSLRRVFDVSRSVDTLIWALMWINVVGLGPFAGALAIACADFGAFGKLFSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AIEAADRKPVEGVLASGGSGLHRVRFALVPQILPVIASQILYFFESNTRSATIIGIVGAG
HHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
GIGGYLTELIRTLEMSQVCVIIIMILITVAVIDFVSSRLRFAIIGRKPASA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9791102 [H]