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The map label for this gene is 158422601

Identifier: 158422601

GI number: 158422601

Start: 1086838

End: 1088136

Strand: Direct

Name: 158422601

Synonym: AZC_0977

Alternate gene names: NA

Gene position: 1086838-1088136 (Clockwise)

Preceding gene: 158422600

Following gene: 158422604

Centisome position: 20.24

GC content: 70.21

Gene sequence:

>1299_bases
GTGAGCCTTGTGCCGGCGCCGGAAGATGGCGCCGTCCGCGCGCTCCGGCACATCGATGCGGGAGCGCGGGCGCTGCTGGT
GCTCGGCGGTGCCGGCACGGGCAAGACCACCTTCCTGCACGAGCTGCGCAAGACGCCGCGTGGGCGCCAGGTTTTCCTCG
CGCCCACGGGCGTTGCCGCCTTGCAGCTCGGCGGCCAGACGCTGCATTCCTTCTTCGGCATTCCGCCGCGCATCCTCCAG
CCGGAGGAGGTGAAGCCGCGCGTTCAGGTGCGCCGGCTTCTGAAGAAGCTGGACCGGCTGGTCATCGACGAAATCTCCAT
GGTGCGGGCGGACCTGCTCGATACGGTGGACCGCACCCTGCGCATCGCCCGCGAGAGCAACACGCCCTTCGGCGGCGTGC
AGGTGGTGCTGGTGGGCGACTTCCTCCAGCTTCCGCCCGTGGTGCCCTATGCGGAGCAGGAGATCCTCGAGCATATGGGC
TACGAGGGACCCTTCGCCTTCCATGCCAAGGTGCTGTCCGATCATCCCGTGGCCCGCGTGCCCTTCACCGTGGTCCACCG
CCAGCAGGACGACGCCTTCATCGGCCATCTCTCCGCCATCCGGCGCGGCGAGCGGCTGAACGAGGCGCTGACCGCGCTGA
ACGAGGCCTGCGTGCGACCGCACCGGTCCGGCGTGCTGCCCGTTCTGCTCACGCCCACCAATGCGCGGGCGGATGCCTAT
AACCAGCGCGGCCTTGCGGCCTTGCCGGGTGGCGAGCGGCAGTTCGAGGGGGTGCTGAAGGGCGAGTTCGGGCTTGATGG
CGACCGCCTGCCGGTGCCCGAACGCCTCGTGCTGAAGACCGGCGCCCGCGTGATGGCGCTGCGCAACGATCCGGCGCGCC
GCTGGGTGAACGGCTCGGTTGGTACGGTGACAGGCATCGGCCCGCACAGCGCGCTGGTACGGCTCGATGGCGGCGGGTCG
GTGGAGATCGAGGCCTTCACCTGGGAGCGCATGCGCTACGTCTTCGACGAGAAGACGGGGAAGATCGAGAGCGACGTGGT
GGGCACCTACACGCAGCTTCCGCTGGTGCCGGCCTGGGCCATGACCATGCACAAGGCGCAGGGCCTGACGCTGGAAGACG
TGCGCATCGACTTCGACAACGGCGCCTTCGCGGCGGGGCAGGCCTATGTGGCCCTCTCCCGCGCCCGCTCGCTGGCGGGC
CTGTCGCTGGTGCGGCCCATCCGGCCCTCGGACATCAAGGTGGACCGGCGGGTCGCCGCGTTCGTGCGCGACTTCGAGGC
GAGCGCGCTGGCCGGCTGA

Upstream 100 bases:

>100_bases
TGCGCATCGGCGCGCTCGCCGCGTCCGAGATCATCTCCCACATGGGCGCCCGGCCCGAGCGCAACCTGCTCGACTACGCC
CGCGAGACCGGTCTGCTGCC

Downstream 100 bases:

>100_bases
GGCCCGTCGCTCAGGCGGGCGTCAGCCCGACAATGCCGTGGCGGGAGACGGCCTGCGTGATCACCGAAGCGGCGCTCTGC
GCCACGAAGGCATTGATCGC

Product: TPR domain-containing protein

Products: NA

Alternate protein names: Helicase; TPR Domain Protein; TPR Domain-Containing Protein; ATPase; Exonuclease V Subunit Alpha; 5-3' DNA Helicase; Helicase-Related Protein; Aaa ATPase; Glycosysltransferase; Hrdc Domain Protein; Helicase-Family Protein; Helicase Protein; HRDC Domain Protein; RecD-Like Exodeoxyribonuclease V Alpha Chain; RRM3/PIF1 Helicase-Like Protein; ATP-Dependent ExoDNAse Alpha Subunit; DNA Helicase AAA ATPase; DNA Helicase/AAA ATPase; Helicase RecD/TraA Family

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MSLVPAPEDGAVRALRHIDAGARALLVLGGAGTGKTTFLHELRKTPRGRQVFLAPTGVAALQLGGQTLHSFFGIPPRILQ
PEEVKPRVQVRRLLKKLDRLVIDEISMVRADLLDTVDRTLRIARESNTPFGGVQVVLVGDFLQLPPVVPYAEQEILEHMG
YEGPFAFHAKVLSDHPVARVPFTVVHRQQDDAFIGHLSAIRRGERLNEALTALNEACVRPHRSGVLPVLLTPTNARADAY
NQRGLAALPGGERQFEGVLKGEFGLDGDRLPVPERLVLKTGARVMALRNDPARRWVNGSVGTVTGIGPHSALVRLDGGGS
VEIEAFTWERMRYVFDEKTGKIESDVVGTYTQLPLVPAWAMTMHKAQGLTLEDVRIDFDNGAFAAGQAYVALSRARSLAG
LSLVRPIRPSDIKVDRRVAAFVRDFEASALAG

Sequences:

>Translated_432_residues
MSLVPAPEDGAVRALRHIDAGARALLVLGGAGTGKTTFLHELRKTPRGRQVFLAPTGVAALQLGGQTLHSFFGIPPRILQ
PEEVKPRVQVRRLLKKLDRLVIDEISMVRADLLDTVDRTLRIARESNTPFGGVQVVLVGDFLQLPPVVPYAEQEILEHMG
YEGPFAFHAKVLSDHPVARVPFTVVHRQQDDAFIGHLSAIRRGERLNEALTALNEACVRPHRSGVLPVLLTPTNARADAY
NQRGLAALPGGERQFEGVLKGEFGLDGDRLPVPERLVLKTGARVMALRNDPARRWVNGSVGTVTGIGPHSALVRLDGGGS
VEIEAFTWERMRYVFDEKTGKIESDVVGTYTQLPLVPAWAMTMHKAQGLTLEDVRIDFDNGAFAAGQAYVALSRARSLAG
LSLVRPIRPSDIKVDRRVAAFVRDFEASALAG
>Mature_431_residues
SLVPAPEDGAVRALRHIDAGARALLVLGGAGTGKTTFLHELRKTPRGRQVFLAPTGVAALQLGGQTLHSFFGIPPRILQP
EEVKPRVQVRRLLKKLDRLVIDEISMVRADLLDTVDRTLRIARESNTPFGGVQVVLVGDFLQLPPVVPYAEQEILEHMGY
EGPFAFHAKVLSDHPVARVPFTVVHRQQDDAFIGHLSAIRRGERLNEALTALNEACVRPHRSGVLPVLLTPTNARADAYN
QRGLAALPGGERQFEGVLKGEFGLDGDRLPVPERLVLKTGARVMALRNDPARRWVNGSVGTVTGIGPHSALVRLDGGGSV
EIEAFTWERMRYVFDEKTGKIESDVVGTYTQLPLVPAWAMTMHKAQGLTLEDVRIDFDNGAFAAGQAYVALSRARSLAGL
SLVRPIRPSDIKVDRRVAAFVRDFEASALAG

Specific function: Unknown

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI82546872, Length=426, Percent_Identity=37.793427230047, Blast_Score=192, Evalue=7e-49,
Organism=Caenorhabditis elegans, GI25143421, Length=429, Percent_Identity=31.4685314685315, Blast_Score=185, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17566502, Length=127, Percent_Identity=35.4330708661417, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321820, Length=301, Percent_Identity=33.2225913621262, Blast_Score=136, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6323579, Length=299, Percent_Identity=33.1103678929766, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI19920652, Length=416, Percent_Identity=31.0096153846154, Blast_Score=162, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 47095; Mature: 46964

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVPAPEDGAVRALRHIDAGARALLVLGGAGTGKTTFLHELRKTPRGRQVFLAPTGVAA
CCCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCHHH
LQLGGQTLHSFFGIPPRILQPEEVKPRVQVRRLLKKLDRLVIDEISMVRADLLDTVDRTL
HHHCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIARESNTPFGGVQVVLVGDFLQLPPVVPYAEQEILEHMGYEGPFAFHAKVLSDHPVARV
HHHHCCCCCCCCEEEEEEECHHHCCCCCCCHHHHHHHHCCCCCCHHEEEHHHCCCCCCCC
PFTVVHRQQDDAFIGHLSAIRRGERLNEALTALNEACVRPHRSGVLPVLLTPTNARADAY
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCC
NQRGLAALPGGERQFEGVLKGEFGLDGDRLPVPERLVLKTGARVMALRNDPARRWVNGSV
CCCCCEECCCCCHHHHHEECCCCCCCCCCCCCCHHHHHHCCCEEEEECCCCHHHHCCCCC
GTVTGIGPHSALVRLDGGGSVEIEAFTWERMRYVFDEKTGKIESDVVGTYTQLPLVPAWA
CEEEECCCCCEEEEECCCCEEEEEEEHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHH
MTMHKAQGLTLEDVRIDFDNGAFAAGQAYVALSRARSLAGLSLVRPIRPSDIKVDRRVAA
HHHHHHCCCEEEEEEEEECCCCEECCHHHHHHHHHHHHHCHHHHCCCCCCCCCHHHHHHH
FVRDFEASALAG
HHHHHHHHHCCC
>Mature Secondary Structure 
SLVPAPEDGAVRALRHIDAGARALLVLGGAGTGKTTFLHELRKTPRGRQVFLAPTGVAA
CCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCHHH
LQLGGQTLHSFFGIPPRILQPEEVKPRVQVRRLLKKLDRLVIDEISMVRADLLDTVDRTL
HHHCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIARESNTPFGGVQVVLVGDFLQLPPVVPYAEQEILEHMGYEGPFAFHAKVLSDHPVARV
HHHHCCCCCCCCEEEEEEECHHHCCCCCCCHHHHHHHHCCCCCCHHEEEHHHCCCCCCCC
PFTVVHRQQDDAFIGHLSAIRRGERLNEALTALNEACVRPHRSGVLPVLLTPTNARADAY
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCC
NQRGLAALPGGERQFEGVLKGEFGLDGDRLPVPERLVLKTGARVMALRNDPARRWVNGSV
CCCCCEECCCCCHHHHHEECCCCCCCCCCCCCCHHHHHHCCCEEEEECCCCHHHHCCCCC
GTVTGIGPHSALVRLDGGGSVEIEAFTWERMRYVFDEKTGKIESDVVGTYTQLPLVPAWA
CEEEECCCCCEEEEECCCCEEEEEEEHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHH
MTMHKAQGLTLEDVRIDFDNGAFAAGQAYVALSRARSLAGLSLVRPIRPSDIKVDRRVAA
HHHHHHCCCEEEEEEEEECCCCEECCHHHHHHHHHHHHHCHHHHCCCCCCCCCHHHHHHH
FVRDFEASALAG
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA