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The map label for this gene is 158422587

Identifier: 158422587

GI number: 158422587

Start: 1073951

End: 1075519

Strand: Direct

Name: 158422587

Synonym: AZC_0963

Alternate gene names: NA

Gene position: 1073951-1075519 (Clockwise)

Preceding gene: 158422586

Following gene: 158422590

Centisome position: 20.0

GC content: 65.01

Gene sequence:

>1569_bases
ATGGCTCAGTTCGACAGGAACGATGACAGCGTTGTGGTGATCGTCGGCTCAGGAGCTGGCGGCGGCACGCTGGGCAATGA
ACTCGCCCAGAAGGGCATCAAGGTGGTGATCCTCGAGGCCGGGGCGCGCAACGAGATCCAGGATTTCGTCAATGACGAAT
GGGAGAGCTTCGCCCAGCTCGCCTGGACCGACATGCGCGTTGCCTCCGGCTCGTGGCGGGTGGCGCGGGATTTCCCGAAC
CTGCCGGCGTGGATCGTGAAATCCGTGGGCGGCTCCACCGTCCATTGGGCGGGCGCCTCGCTGCGCTTCGAGCAGCACGA
GTTCAAGGCCGCCTCAGCCTATGGCGGCATCAAGGGCGCCAACCTCCTTGACTGGCCGATCACCAAGGCGGAACTCGACC
CATATTACGCCAAGGCCGAAGACAAGATGGGGGTGACGCGCACCAACAACATCCCCGGCCTGCCCGGCAACAACAACGAG
AAGGTGCTGGAGGCCGGCGCCCGCAAGATCGGCTACAAGGACTTCTCCACCGGGCGCATGGCCATCAACAGCCAGCCCCG
CGACGGGCGCGGCTCCTGCCAGCAGATCGGTTTCTGCTTCCAGGGCTGCAAGTCCGGCGCCAAATGGTCCACGCTCTATA
CGGAAATCCCCAAGGGCGAGGCCACCGGCAATCTGGAAGTGCGGCCCAACTGCCACGTGGCGAAGATCGAGCACGACGCC
AATGGCAAAGTGACGGCGGTGGTCTATTTCGACGAGACCGGCGCCACCCAGCGGCAGAAGGCCCGCGTGGTCGCTGTGGC
GGGCAATTCCATCGAAAGCCCGCGCCTGCTTCTCAACAGCGCGTCCAGCCTGTTCCCGAACGGCCTTGCCAATTCCTCGG
GGCAGGTGGGGCGCAACTACATGCGCCACGTCACCGGCTCGGTCTATGCCGCCTTCGAGAAGCCGGTGCACATGTATCGC
GGCACCACCATGGCCGGCATCATCCGCGATGAGGCGCGGCACGATCCCGGCCGTGGCTTTGCCGGCGGCTACGAGATGGA
GACGCTCTCCCTCGGCCTGCCCTTCATGGCCGCCTTCCTGAACCCCGGCGCGTGGGGCCGCAGCTTCACCTCGGCCATGG
AGAATTATCCCCGCATGGCCGGCATGTGGCTGGTGGGCGAGGACATGCCGCAGGAGAAGAACGCCATCACGCTGGACAAG
GAGGCCAAGGACAAGTTCGGCCTGCCGGTGGCCAACGTGCATTATGACGACCATTCCAATGACGTGGCCATGCGCAACCA
CGGCTACCAGCAGGGGGCGGCGCTCTATGAGGCGGTGGGGGCGGTGCAGACCTATCCCACCACGCCCTATCCCAGCACGC
ACAACCTCGGCACCAACCGCATGAGCGAGAAGCCGCGCGACGGGGTGGTCAACAAGTTCGGCCAGTCGCACGACATCAAG
AATTTGTTCGTGTCGGATGGCAGCCAGTTCACCACCAGCGCGGCCTGTAATCCCACGCTCACCATCGTCGCCCTCGCCAT
CCGGCAGGCCGACCACATGGCCGAACTGATGCGCCGGCGCGACATCTGA

Upstream 100 bases:

>100_bases
CTGGCTGCCGAAGGCCTGATGCTGAGGCGCGCCCACGAACGGGCGCCGCCACCAAAGAAAAGACCGACAGGGAAACGCCA
AACAGCCGGGAGGAACGTCC

Downstream 100 bases:

>100_bases
CGGGTACGTCCGGCGGCAACGGCCGACGTGGACACCGTGACCCAAGTCGGATGGCCGGGCGTCTCCCGGCCATCTAAGCC
CGCCTTCCTCTACTCCGCGG

Product: 2-keto-gluconate dehydrogenase

Products: NA

Alternate protein names: GA 2-DH dehydrogenase subunit; GADH dehydrogenase subunit [H]

Number of amino acids: Translated: 522; Mature: 521

Protein sequence:

>522_residues
MAQFDRNDDSVVVIVGSGAGGGTLGNELAQKGIKVVILEAGARNEIQDFVNDEWESFAQLAWTDMRVASGSWRVARDFPN
LPAWIVKSVGGSTVHWAGASLRFEQHEFKAASAYGGIKGANLLDWPITKAELDPYYAKAEDKMGVTRTNNIPGLPGNNNE
KVLEAGARKIGYKDFSTGRMAINSQPRDGRGSCQQIGFCFQGCKSGAKWSTLYTEIPKGEATGNLEVRPNCHVAKIEHDA
NGKVTAVVYFDETGATQRQKARVVAVAGNSIESPRLLLNSASSLFPNGLANSSGQVGRNYMRHVTGSVYAAFEKPVHMYR
GTTMAGIIRDEARHDPGRGFAGGYEMETLSLGLPFMAAFLNPGAWGRSFTSAMENYPRMAGMWLVGEDMPQEKNAITLDK
EAKDKFGLPVANVHYDDHSNDVAMRNHGYQQGAALYEAVGAVQTYPTTPYPSTHNLGTNRMSEKPRDGVVNKFGQSHDIK
NLFVSDGSQFTTSAACNPTLTIVALAIRQADHMAELMRRRDI

Sequences:

>Translated_522_residues
MAQFDRNDDSVVVIVGSGAGGGTLGNELAQKGIKVVILEAGARNEIQDFVNDEWESFAQLAWTDMRVASGSWRVARDFPN
LPAWIVKSVGGSTVHWAGASLRFEQHEFKAASAYGGIKGANLLDWPITKAELDPYYAKAEDKMGVTRTNNIPGLPGNNNE
KVLEAGARKIGYKDFSTGRMAINSQPRDGRGSCQQIGFCFQGCKSGAKWSTLYTEIPKGEATGNLEVRPNCHVAKIEHDA
NGKVTAVVYFDETGATQRQKARVVAVAGNSIESPRLLLNSASSLFPNGLANSSGQVGRNYMRHVTGSVYAAFEKPVHMYR
GTTMAGIIRDEARHDPGRGFAGGYEMETLSLGLPFMAAFLNPGAWGRSFTSAMENYPRMAGMWLVGEDMPQEKNAITLDK
EAKDKFGLPVANVHYDDHSNDVAMRNHGYQQGAALYEAVGAVQTYPTTPYPSTHNLGTNRMSEKPRDGVVNKFGQSHDIK
NLFVSDGSQFTTSAACNPTLTIVALAIRQADHMAELMRRRDI
>Mature_521_residues
AQFDRNDDSVVVIVGSGAGGGTLGNELAQKGIKVVILEAGARNEIQDFVNDEWESFAQLAWTDMRVASGSWRVARDFPNL
PAWIVKSVGGSTVHWAGASLRFEQHEFKAASAYGGIKGANLLDWPITKAELDPYYAKAEDKMGVTRTNNIPGLPGNNNEK
VLEAGARKIGYKDFSTGRMAINSQPRDGRGSCQQIGFCFQGCKSGAKWSTLYTEIPKGEATGNLEVRPNCHVAKIEHDAN
GKVTAVVYFDETGATQRQKARVVAVAGNSIESPRLLLNSASSLFPNGLANSSGQVGRNYMRHVTGSVYAAFEKPVHMYRG
TTMAGIIRDEARHDPGRGFAGGYEMETLSLGLPFMAAFLNPGAWGRSFTSAMENYPRMAGMWLVGEDMPQEKNAITLDKE
AKDKFGLPVANVHYDDHSNDVAMRNHGYQQGAALYEAVGAVQTYPTTPYPSTHNLGTNRMSEKPRDGVVNKFGQSHDIKN
LFVSDGSQFTTSAACNPTLTIVALAIRQADHMAELMRRRDI

Specific function: Part of the heterotrimer that catalyzes the conversion of D-gluconate to 2-dehydro-D-gluconate. This subunit functions as the dehydrogenase [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.3 [H]

Molecular weight: Translated: 56798; Mature: 56667

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQFDRNDDSVVVIVGSGAGGGTLGNELAQKGIKVVILEAGARNEIQDFVNDEWESFAQL
CCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
AWTDMRVASGSWRVARDFPNLPAWIVKSVGGSTVHWAGASLRFEQHEFKAASAYGGIKGA
HHHHEEEECCCCEEECCCCCCHHHHHHHCCCCEEEECCCEEEEHHHHHHHHHHCCCCCCC
NLLDWPITKAELDPYYAKAEDKMGVTRTNNIPGLPGNNNEKVLEAGARKIGYKDFSTGRM
CEECCCCCHHHCCCHHHCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEE
AINSQPRDGRGSCQQIGFCFQGCKSGAKWSTLYTEIPKGEATGNLEVRPNCHVAKIEHDA
EECCCCCCCCCCHHHHHHHHHHHCCCCCEEEHEEECCCCCCCCCEEECCCCEEEEEEECC
NGKVTAVVYFDETGATQRQKARVVAVAGNSIESPRLLLNSASSLFPNGLANSSGQVGRNY
CCCEEEEEEECCCCCCCHHCEEEEEEECCCCCCCHHHHHCHHHHCCCCCCCCCCHHHHHH
MRHVTGSVYAAFEKPVHMYRGTTMAGIIRDEARHDPGRGFAGGYEMETLSLGLPFMAAFL
HHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHC
NPGAWGRSFTSAMENYPRMAGMWLVGEDMPQEKNAITLDKEAKDKFGLPVANVHYDDHSN
CCCCCCHHHHHHHHHCCHHCEEEEECCCCCCCCCCEEECCCCHHHHCCCEEEEEECCCCC
DVAMRNHGYQQGAALYEAVGAVQTYPTTPYPSTHNLGTNRMSEKPRDGVVNKFGQSHDIK
CEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCH
NLFVSDGSQFTTSAACNPTLTIVALAIRQADHMAELMRRRDI
HHEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AQFDRNDDSVVVIVGSGAGGGTLGNELAQKGIKVVILEAGARNEIQDFVNDEWESFAQL
CCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
AWTDMRVASGSWRVARDFPNLPAWIVKSVGGSTVHWAGASLRFEQHEFKAASAYGGIKGA
HHHHEEEECCCCEEECCCCCCHHHHHHHCCCCEEEECCCEEEEHHHHHHHHHHCCCCCCC
NLLDWPITKAELDPYYAKAEDKMGVTRTNNIPGLPGNNNEKVLEAGARKIGYKDFSTGRM
CEECCCCCHHHCCCHHHCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEE
AINSQPRDGRGSCQQIGFCFQGCKSGAKWSTLYTEIPKGEATGNLEVRPNCHVAKIEHDA
EECCCCCCCCCCHHHHHHHHHHHCCCCCEEEHEEECCCCCCCCCEEECCCCEEEEEEECC
NGKVTAVVYFDETGATQRQKARVVAVAGNSIESPRLLLNSASSLFPNGLANSSGQVGRNY
CCCEEEEEEECCCCCCCHHCEEEEEEECCCCCCCHHHHHCHHHHCCCCCCCCCCHHHHHH
MRHVTGSVYAAFEKPVHMYRGTTMAGIIRDEARHDPGRGFAGGYEMETLSLGLPFMAAFL
HHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHC
NPGAWGRSFTSAMENYPRMAGMWLVGEDMPQEKNAITLDKEAKDKFGLPVANVHYDDHSN
CCCCCCHHHHHHHHHCCHHCEEEEECCCCCCCCCCEEECCCCHHHHCCCEEEEEECCCCC
DVAMRNHGYQQGAALYEAVGAVQTYPTTPYPSTHNLGTNRMSEKPRDGVVNKFGQSHDIK
CEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCH
NLFVSDGSQFTTSAACNPTLTIVALAIRQADHMAELMRRRDI
HHEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9352901 [H]