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The map label for this gene is fae [H]

Identifier: 158422514

GI number: 158422514

Start: 997521

End: 998051

Strand: Reverse

Name: fae [H]

Synonym: AZC_0890

Alternate gene names: 158422514

Gene position: 998051-997521 (Counterclockwise)

Preceding gene: 158422515

Following gene: 158422503

Centisome position: 18.59

GC content: 66.29

Gene sequence:

>531_bases
GTGCATGCGTGGCGGAGTGCCGGCGGAATGCCGAAGATCCATAAGATGATGGCCGGCGAAGCCATGGTGGGCGACGGCAA
CGAAGTCGCCCATATCGATCTCGTGATCGGCCCGCGCGGCTCGTCGGCGGAGACCGCCTTCGTCACGGCGCTTACCAACA
ACAAGGACGGCTTCACCACCCTGCTCGCGGTGCTGGAGCCGAACGTGCTGGCCAAGCCCAACACCGTCCTGTTCAACAAG
GTGGTGCTGAAGGGTGCCCGTCAGGCCGCCCAGATGTTCGGCCCCGCCCAGTATGCGGTGGCGCGGGCTGTGGTGGATTC
GGTGGCCGAAGGCATCATCCCGCAGGAGGAGGCGGACGACCTCTTCATCGCCGTGGGCGTCTTCATCCATTGGCAGGCGC
AGGACGATGCGCGCATCCAGGCTTTCAACTATGCCGCCACCAAGCTGGCGCTGGCCCGCGCGGTCGCCGGCCAGCCCACC
GTCGCCGAGGTGCTGGAAAAGGCGAAGAGCCTGCCGCCCTTCGAACTCTGA

Upstream 100 bases:

>100_bases
TCTTAATCTGCGGCGGGAATCCCGCTACAGCCTGAGTGATGAACAGGTCCCTCGGGACCGGGGTGGCCCCGATGCCGCGC
GCTCGCGCGCGATCGGTCGG

Downstream 100 bases:

>100_bases
AGCGGGGTCGGCTGCGGGCCGCGCCCTACTGCGCATCCCCCATGCGGGGATGGCCGGCGGGGATGGAGGCGAGCAGCCCC
ACCAGTTCCGCCTGCCGGGT

Product: formaldehyde-activating enzyme

Products: NA

Alternate protein names: Fae [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MHAWRSAGGMPKIHKMMAGEAMVGDGNEVAHIDLVIGPRGSSAETAFVTALTNNKDGFTTLLAVLEPNVLAKPNTVLFNK
VVLKGARQAAQMFGPAQYAVARAVVDSVAEGIIPQEEADDLFIAVGVFIHWQAQDDARIQAFNYAATKLALARAVAGQPT
VAEVLEKAKSLPPFEL

Sequences:

>Translated_176_residues
MHAWRSAGGMPKIHKMMAGEAMVGDGNEVAHIDLVIGPRGSSAETAFVTALTNNKDGFTTLLAVLEPNVLAKPNTVLFNK
VVLKGARQAAQMFGPAQYAVARAVVDSVAEGIIPQEEADDLFIAVGVFIHWQAQDDARIQAFNYAATKLALARAVAGQPT
VAEVLEKAKSLPPFEL
>Mature_176_residues
MHAWRSAGGMPKIHKMMAGEAMVGDGNEVAHIDLVIGPRGSSAETAFVTALTNNKDGFTTLLAVLEPNVLAKPNTVLFNK
VVLKGARQAAQMFGPAQYAVARAVVDSVAEGIIPQEEADDLFIAVGVFIHWQAQDDARIQAFNYAATKLALARAVAGQPT
VAEVLEKAKSLPPFEL

Specific function: Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin. Is an essential enzyme for methylotrophic energy metabolism and formaldehyde detoxification of this bacterium [H]

COG id: COG1795

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the formaldehyde-activating enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014826
- InterPro:   IPR020568 [H]

Pfam domain/function: PF08714 Fae [H]

EC number: NA

Molecular weight: Translated: 18694; Mature: 18694

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAWRSAGGMPKIHKMMAGEAMVGDGNEVAHIDLVIGPRGSSAETAFVTALTNNKDGFTT
CCCCCCCCCCHHHHHHHCCCEEECCCCCEEEEEEEECCCCCCCCEEEEEEEECCCCHHHH
LLAVLEPNVLAKPNTVLFNKVVLKGARQAAQMFGPAQYAVARAVVDSVAEGIIPQEEADD
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCC
LFIAVGVFIHWQAQDDARIQAFNYAATKLALARAVAGQPTVAEVLEKAKSLPPFEL
EEEEEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MHAWRSAGGMPKIHKMMAGEAMVGDGNEVAHIDLVIGPRGSSAETAFVTALTNNKDGFTT
CCCCCCCCCCHHHHHHHCCCEEECCCCCEEEEEEEECCCCCCCCEEEEEEEECCCCHHHH
LLAVLEPNVLAKPNTVLFNKVVLKGARQAAQMFGPAQYAVARAVVDSVAEGIIPQEEADD
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCC
LFIAVGVFIHWQAQDDARIQAFNYAATKLALARAVAGQPTVAEVLEKAKSLPPFEL
EEEEEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9651254; 11073907 [H]