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The map label for this gene is catB1 [H]

Identifier: 158422443

GI number: 158422443

Start: 923278

End: 924408

Strand: Direct

Name: catB1 [H]

Synonym: AZC_0819

Alternate gene names: 158422443

Gene position: 923278-924408 (Clockwise)

Preceding gene: 158422442

Following gene: 158422444

Centisome position: 17.19

GC content: 67.9

Gene sequence:

>1131_bases
ATGAGCTGGGACAGCGTCGTCGAGCGTATCCGCATCTTCCTCGTGGAGAGCCCCATCAAGATGGCCCGCCTTCAGGGCGT
CGGCAATGTGAAGGGCTCCGTGAAGCGCGTGCTGCTGGAAGTGACCAGCGCCGACGGCATCGTGGGCTGGGGCGAGGCGG
CCCCGTGGGAGGTGTTCACCGGCACGCCGGAAGCCGCCTTCTCCGCCCTCGACATCTACCTGCGTCCGCTCATCCTCGGC
GCGCCCATCAAGCGTGTGCGCGAGCTGATGGCGCGCATGGACAAGATGCTGGTCGGCCATGGCGAGGCCAAGGCGGCGGT
CGAGATGGCGCTGCTGGACATCCTCGGCAAGGCGACGGGCCTCTCCGTGGCGGACCTGCTGGGCGGGCGGGTGCGAGACC
GCATCCCGCTGTCCTTCTCCATTGCGGACCCGGACTTCGACGCGGATCTCGAGCGGATGCGCGCCATGGTCCCAGCCGGG
CACACCGTCTTCAAGATGAAGACCGGCGTGAAGCCGCACGCGGAAGAGCTGCGCATCCTGGAGACCATGCGGGGCGAATT
CGGCGAGCGGATCGACCTGCGGCTCGACTTCAATCAGGCCCTGACGCCGTTCGGCGCCATGAAGATCCTGCGGGATGTGG
ACGCCTTCCGCCCCACCTTCATCGAGCAGCCGGTGCCGCGTCGCCACCTCGACGCCATGGCCGGCTTCGCCGCCGCGCTC
GACACGCCCATCCTCGCGGATGAAAGCTGCTTCGATGCGGTGGACCTGATGGAGGTGGTGCGCCGGCAGGCGGCGGATGC
CATCTCGGTCAAGATCATGAAGTGCGGCGGCCTCATGAAGGCGCAGTCCCTCATGGCCATTGCCGACACCGCCGGCCTGC
CGGGCTATGGCGGCACGCTGTGGGAAGGCGGCATTGCGCTCGCCGCCGGCACGCAACTCATCGCCGCGACGCCGGGCATC
TCGCTCGGCTGCGAATTCTACATGCCCCACCATGTGCTCACCGAGGACGTGCTGGAAGAGCGCATCGCTAACAGCGCGGG
TCATGTGATCGTGCCCGATGGTCCCGGCCTCGGCATCTCCATCAGCGAGGCCTCGCTGCGCGGCAACGCCAAGATCCTCG
CCGAGCGCTGA

Upstream 100 bases:

>100_bases
GCCTTCCTGTCCCACTTCCACAAGCGCGGCGAGGCCCCGGCGCCGAGCGCCTGATCCCTGGCCTCCGGCCGCACCCCTAT
CTGCCTGAAAGGACCCCGCG

Downstream 100 bases:

>100_bases
AGCCTCTTTCCGGACCAGACCCATGAGCCTCCATATCGTCGTCATCGGTGCCGGCATCGTCGGCGCCTCAACCGCGCTTG
AACTCCAGCGGGACGGCCAT

Product: muconate cycloisomerase

Products: NA

Alternate protein names: Cis,cis-muconate lactonizing enzyme I 1; MLE 1; Muconate cycloisomerase I 1 [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MSWDSVVERIRIFLVESPIKMARLQGVGNVKGSVKRVLLEVTSADGIVGWGEAAPWEVFTGTPEAAFSALDIYLRPLILG
APIKRVRELMARMDKMLVGHGEAKAAVEMALLDILGKATGLSVADLLGGRVRDRIPLSFSIADPDFDADLERMRAMVPAG
HTVFKMKTGVKPHAEELRILETMRGEFGERIDLRLDFNQALTPFGAMKILRDVDAFRPTFIEQPVPRRHLDAMAGFAAAL
DTPILADESCFDAVDLMEVVRRQAADAISVKIMKCGGLMKAQSLMAIADTAGLPGYGGTLWEGGIALAAGTQLIAATPGI
SLGCEFYMPHHVLTEDVLEERIANSAGHVIVPDGPGLGISISEASLRGNAKILAER

Sequences:

>Translated_376_residues
MSWDSVVERIRIFLVESPIKMARLQGVGNVKGSVKRVLLEVTSADGIVGWGEAAPWEVFTGTPEAAFSALDIYLRPLILG
APIKRVRELMARMDKMLVGHGEAKAAVEMALLDILGKATGLSVADLLGGRVRDRIPLSFSIADPDFDADLERMRAMVPAG
HTVFKMKTGVKPHAEELRILETMRGEFGERIDLRLDFNQALTPFGAMKILRDVDAFRPTFIEQPVPRRHLDAMAGFAAAL
DTPILADESCFDAVDLMEVVRRQAADAISVKIMKCGGLMKAQSLMAIADTAGLPGYGGTLWEGGIALAAGTQLIAATPGI
SLGCEFYMPHHVLTEDVLEERIANSAGHVIVPDGPGLGISISEASLRGNAKILAER
>Mature_375_residues
SWDSVVERIRIFLVESPIKMARLQGVGNVKGSVKRVLLEVTSADGIVGWGEAAPWEVFTGTPEAAFSALDIYLRPLILGA
PIKRVRELMARMDKMLVGHGEAKAAVEMALLDILGKATGLSVADLLGGRVRDRIPLSFSIADPDFDADLERMRAMVPAGH
TVFKMKTGVKPHAEELRILETMRGEFGERIDLRLDFNQALTPFGAMKILRDVDAFRPTFIEQPVPRRHLDAMAGFAAALD
TPILADESCFDAVDLMEVVRRQAADAISVKIMKCGGLMKAQSLMAIADTAGLPGYGGTLWEGGIALAAGTQLIAATPGIS
LGCEFYMPHHVLTEDVLEERIANSAGHVIVPDGPGLGISISEASLRGNAKILAER

Specific function: Catalyzes a syn cycloisomerization [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI48994953, Length=360, Percent_Identity=26.1111111111111, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787864, Length=370, Percent_Identity=23.5135135135135, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013370
- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =5.5.1.1 [H]

Molecular weight: Translated: 40493; Mature: 40362

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00908 MR_MLE_1 ; PS00909 MR_MLE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWDSVVERIRIFLVESPIKMARLQGVGNVKGSVKRVLLEVTSADGIVGWGEAAPWEVFT
CCHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCEEEC
GTPEAAFSALDIYLRPLILGAPIKRVRELMARMDKMLVGHGEAKAAVEMALLDILGKATG
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
LSVADLLGGRVRDRIPLSFSIADPDFDADLERMRAMVPAGHTVFKMKTGVKPHAEELRIL
CHHHHHHCCHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHH
ETMRGEFGERIDLRLDFNQALTPFGAMKILRDVDAFRPTFIEQPVPRRHLDAMAGFAAAL
HHHHHHCCCEEEEEECCHHHCCHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHH
DTPILADESCFDAVDLMEVVRRQAADAISVKIMKCGGLMKAQSLMAIADTAGLPGYGGTL
CCCCCCCCHHHHHHHHHHHHHHHHCHHHEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCH
WEGGIALAAGTQLIAATPGISLGCEFYMPHHVLTEDVLEERIANSAGHVIVPDGPGLGIS
HCCCEEEECCCEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHCCCCEEEECCCCCCEEE
ISEASLRGNAKILAER
EEHHHCCCCCEEEECC
>Mature Secondary Structure 
SWDSVVERIRIFLVESPIKMARLQGVGNVKGSVKRVLLEVTSADGIVGWGEAAPWEVFT
CHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCEEEC
GTPEAAFSALDIYLRPLILGAPIKRVRELMARMDKMLVGHGEAKAAVEMALLDILGKATG
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
LSVADLLGGRVRDRIPLSFSIADPDFDADLERMRAMVPAGHTVFKMKTGVKPHAEELRIL
CHHHHHHCCHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHH
ETMRGEFGERIDLRLDFNQALTPFGAMKILRDVDAFRPTFIEQPVPRRHLDAMAGFAAAL
HHHHHHCCCEEEEEECCHHHCCHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHH
DTPILADESCFDAVDLMEVVRRQAADAISVKIMKCGGLMKAQSLMAIADTAGLPGYGGTL
CCCCCCCCHHHHHHHHHHHHHHHHCHHHEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCH
WEGGIALAAGTQLIAATPGISLGCEFYMPHHVLTEDVLEERIANSAGHVIVPDGPGLGIS
HCCCEEEECCCEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHCCCCEEEECCCCCCEEE
ISEASLRGNAKILAER
EEHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9473520; 9260969 [H]