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The map label for this gene is lysR [H]

Identifier: 158422415

GI number: 158422415

Start: 893325

End: 894362

Strand: Reverse

Name: lysR [H]

Synonym: AZC_0791

Alternate gene names: 158422415

Gene position: 894362-893325 (Counterclockwise)

Preceding gene: 158422418

Following gene: 158422413

Centisome position: 16.66

GC content: 68.3

Gene sequence:

>1038_bases
GTGACGGATCGCGCAGCCCGGCGGGGCGCAATTGCGGCGGCGCCCGGCCCGATGGCATTGGCCACGGGGAGCGCCTTGGA
TAGAGTGCCGGCAATCCAGAGGATCGACGGCGTGCTCGAAAACATGCGGGCTTTCACCCAGGCGGTGGAAAGCGACAGCT
TCTCGGAGGCGGCACGGCGGCTGCGCGTCTCCCCCAATGTGGTCAGCCACCGCATCCAGGTTCTGGAAAAGCACCTCGGC
TGCCGCCTGTTCAACCGTACCACGCGGCGCATGAGTCTCACGGAACAGGGGCGCGTCTATTACGAGACCGTCACCGAGGC
GCTGCGCCTCATCGATACGGCAGAAACCAGCATTTCCGAACTCGGCGCCCTGCCGCGCGGGGCGCTGCGGGTGACGGCGC
CGCTGCATCTCGGCCGCCGGCTGCTCGCCCCCATGGCGGCGCGCTATCAGGACGCCTATCCGCAGATCGACGTGCGCCTG
CGCCTTTCCGAGCACATGCCCGACCTGATCGCCGAATCCATCGACGTGGCGCTGCGCCTCGCCACCTTCGAGGATTCGAG
CACCATCCTGCGCAAGGTGGCGGAGGTCGACCGCATCCTGTGCGCCGCACCCGCCTATCTGGACCGGCATGGCGTGCCGG
AGAAGCCCGCCGACCTTCTGAACCACCAGTGCCTTCTGATGCGCCACGCCACCTCCCGCGAACTGCGTTGGATGCTCACC
GACAAAGGCAAGGACCTTGCCGTTCCGGTCGCCGGCCATCTCGAGGCGGACGACGGCGACGTGCTCACCGTCTGGGCGGT
GGAAGGACGCGGCATCGTGGTGAAGCCCCGCTTCGAGGTGGCCGACGCGTTGGCCGCGGGCCAGTTGGTGCCCGTGCTGG
AGCGCCACCCGCCGCGCCCGATGACGCTGGCCGTGCTCTATCCGGCCCGCCAGTTGGTGCCGCTGAAGGTGAAGACCTTC
GCGGACATGCTGGTGGAGGACGCCCGCCGCTATGTGGCGCGGGAACTGGCCAAAATCGGCGAGAAGCTGCCTTCCTGA

Upstream 100 bases:

>100_bases
TAGAAGGAGGCGCCGATCCAGGCCATGCCGGCGGTGATGTGGGCCCAGCGCAGCAGCAGGCTGCCGAATTCATGCAGGAT
GGGTTCCATGTCTGCCCTCA

Downstream 100 bases:

>100_bases
AGGGCTGGTGGGTCTTGGGTGGGCGCCGCGCCGTCGCTTTTCCGCAGACGGCGCGCTCGGCCCCAGCCGTTCCACCCCCC
TCCCTGCCCTCCCCCGCAAG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MTDRAARRGAIAAAPGPMALATGSALDRVPAIQRIDGVLENMRAFTQAVESDSFSEAARRLRVSPNVVSHRIQVLEKHLG
CRLFNRTTRRMSLTEQGRVYYETVTEALRLIDTAETSISELGALPRGALRVTAPLHLGRRLLAPMAARYQDAYPQIDVRL
RLSEHMPDLIAESIDVALRLATFEDSSTILRKVAEVDRILCAAPAYLDRHGVPEKPADLLNHQCLLMRHATSRELRWMLT
DKGKDLAVPVAGHLEADDGDVLTVWAVEGRGIVVKPRFEVADALAAGQLVPVLERHPPRPMTLAVLYPARQLVPLKVKTF
ADMLVEDARRYVARELAKIGEKLPS

Sequences:

>Translated_345_residues
MTDRAARRGAIAAAPGPMALATGSALDRVPAIQRIDGVLENMRAFTQAVESDSFSEAARRLRVSPNVVSHRIQVLEKHLG
CRLFNRTTRRMSLTEQGRVYYETVTEALRLIDTAETSISELGALPRGALRVTAPLHLGRRLLAPMAARYQDAYPQIDVRL
RLSEHMPDLIAESIDVALRLATFEDSSTILRKVAEVDRILCAAPAYLDRHGVPEKPADLLNHQCLLMRHATSRELRWMLT
DKGKDLAVPVAGHLEADDGDVLTVWAVEGRGIVVKPRFEVADALAAGQLVPVLERHPPRPMTLAVLYPARQLVPLKVKTF
ADMLVEDARRYVARELAKIGEKLPS
>Mature_344_residues
TDRAARRGAIAAAPGPMALATGSALDRVPAIQRIDGVLENMRAFTQAVESDSFSEAARRLRVSPNVVSHRIQVLEKHLGC
RLFNRTTRRMSLTEQGRVYYETVTEALRLIDTAETSISELGALPRGALRVTAPLHLGRRLLAPMAARYQDAYPQIDVRLR
LSEHMPDLIAESIDVALRLATFEDSSTILRKVAEVDRILCAAPAYLDRHGVPEKPADLLNHQCLLMRHATSRELRWMLTD
KGKDLAVPVAGHLEADDGDVLTVWAVEGRGIVVKPRFEVADALAAGQLVPVLERHPPRPMTLAVLYPARQLVPLKVKTFA
DMLVEDARRYVARELAKIGEKLPS

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=297, Percent_Identity=30.976430976431, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI87081978, Length=296, Percent_Identity=31.4189189189189, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1789440, Length=270, Percent_Identity=31.4814814814815, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1786401, Length=291, Percent_Identity=32.3024054982818, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1787128, Length=287, Percent_Identity=29.616724738676, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI145693193, Length=292, Percent_Identity=27.7397260273973, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787589, Length=288, Percent_Identity=28.125, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789173, Length=252, Percent_Identity=27.3809523809524, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788706, Length=259, Percent_Identity=26.6409266409266, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI157672245, Length=144, Percent_Identity=29.1666666666667, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1786448, Length=255, Percent_Identity=26.2745098039216, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI145693105, Length=153, Percent_Identity=27.4509803921569, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788481, Length=169, Percent_Identity=27.810650887574, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788748, Length=136, Percent_Identity=28.6764705882353, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 38185; Mature: 38054

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRAARRGAIAAAPGPMALATGSALDRVPAIQRIDGVLENMRAFTQAVESDSFSEAARR
CCCCHHHCCCEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LRVSPNVVSHRIQVLEKHLGCRLFNRTTRRMSLTEQGRVYYETVTEALRLIDTAETSISE
HCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LGALPRGALRVTAPLHLGRRLLAPMAARYQDAYPQIDVRLRLSEHMPDLIAESIDVALRL
HCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHCCHHHHHHHHHHHEEE
ATFEDSSTILRKVAEVDRILCAAPAYLDRHGVPEKPADLLNHQCLLMRHATSRELRWMLT
EECCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHCCCEEEHHHCCCHHEEEEEE
DKGKDLAVPVAGHLEADDGDVLTVWAVEGRGIVVKPRFEVADALAAGQLVPVLERHPPRP
CCCCEEEEEEECCCCCCCCCEEEEEEECCCEEEECCCHHHHHHHHHCCCCHHHHCCCCCC
MTLAVLYPARQLVPLKVKTFADMLVEDARRYVARELAKIGEKLPS
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDRAARRGAIAAAPGPMALATGSALDRVPAIQRIDGVLENMRAFTQAVESDSFSEAARR
CCCHHHCCCEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LRVSPNVVSHRIQVLEKHLGCRLFNRTTRRMSLTEQGRVYYETVTEALRLIDTAETSISE
HCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LGALPRGALRVTAPLHLGRRLLAPMAARYQDAYPQIDVRLRLSEHMPDLIAESIDVALRL
HCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHCCHHHHHHHHHHHEEE
ATFEDSSTILRKVAEVDRILCAAPAYLDRHGVPEKPADLLNHQCLLMRHATSRELRWMLT
EECCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHCCCEEEHHHCCCHHEEEEEE
DKGKDLAVPVAGHLEADDGDVLTVWAVEGRGIVVKPRFEVADALAAGQLVPVLERHPPRP
CCCCEEEEEEECCCCCCCCCEEEEEEECCCEEEECCCHHHHHHHHHCCCCHHHHCCCCCC
MTLAVLYPARQLVPLKVKTFADMLVEDARRYVARELAKIGEKLPS
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]