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The map label for this gene is marR [H]

Identifier: 158422366

GI number: 158422366

Start: 836916

End: 837497

Strand: Direct

Name: marR [H]

Synonym: AZC_0742

Alternate gene names: 158422366

Gene position: 836916-837497 (Clockwise)

Preceding gene: 158422364

Following gene: 158422367

Centisome position: 15.59

GC content: 63.06

Gene sequence:

>582_bases
TTGCGGGTCGGTGGAAACAGGGGACGCTCTGCGTGCAGCAGATTTTTCCGATTTACGCTTGGAAAGGTCAACACGCGGCC
GGGCGAGAACGAGAGGCTAGAAAGTAAGTTTAACTTATCGTATTGTGGGGGAGATATGTCTGAGACTCCGTTGGGATTTC
TTTTCTTCGAGGTGTCGCGGCTCTACCGGGCGCGCACGGACCGTGCGTTCGAGCAGGGCGGCCTCGGCATCACCTCCGGT
GAGGCCCGCACGCTGATCTACATCAATCAGCATCCGGGCCTGCGCCAGACGGCTCTTGCCGAGAAGATGAGCGTCGAGCC
CATGACGCTGGTGGCTTCTCTCGATCGTCTCGAGGCGCAGAGCCTCGTGAAGCGCGAGCCCGATCCCACCGACCGCCGGG
CGAAACGCGTTCTGCTGACGCCGGCCGCCGCGCCGCTGATCGCGCGCATCACCTCCATCGCGCTCGCCGCGCGGGAGGAA
ATCCTCAACGGCCTCTCGGAAGACCAGATCGCCAATTTCAGGACCGCCCTCGACCGGATGCGCGTGAACCTGGTGGCGGG
GAGAGATGCGGACGACGCATGA

Upstream 100 bases:

>100_bases
GTGCCGCAGGGCTTCTCGCACCGTTTTGGTCCTTTCTCCGCCTCGAATTACAACTTAGAGGTATTATAACCTCGAATGAC
TGCTCTAGGTTCTTTGTGCG

Downstream 100 bases:

>100_bases
AGCCAGTGATGAGTGAAAGCCGCACGGCGGTCATCGGTGCGATGATCGTCGTGCTGGGGCCGATCAGCATGTCGCTCTAC
ACACCGGCCATGCCGGCGCT

Product: transcriptional regulator

Products: NA

Alternate protein names: Regulator of antibiotic and pigment protein [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MRVGGNRGRSACSRFFRFTLGKVNTRPGENERLESKFNLSYCGGDMSETPLGFLFFEVSRLYRARTDRAFEQGGLGITSG
EARTLIYINQHPGLRQTALAEKMSVEPMTLVASLDRLEAQSLVKREPDPTDRRAKRVLLTPAAAPLIARITSIALAAREE
ILNGLSEDQIANFRTALDRMRVNLVAGRDADDA

Sequences:

>Translated_193_residues
MRVGGNRGRSACSRFFRFTLGKVNTRPGENERLESKFNLSYCGGDMSETPLGFLFFEVSRLYRARTDRAFEQGGLGITSG
EARTLIYINQHPGLRQTALAEKMSVEPMTLVASLDRLEAQSLVKREPDPTDRRAKRVLLTPAAAPLIARITSIALAAREE
ILNGLSEDQIANFRTALDRMRVNLVAGRDADDA
>Mature_193_residues
MRVGGNRGRSACSRFFRFTLGKVNTRPGENERLESKFNLSYCGGDMSETPLGFLFFEVSRLYRARTDRAFEQGGLGITSG
EARTLIYINQHPGLRQTALAEKMSVEPMTLVASLDRLEAQSLVKREPDPTDRRAKRVLLTPAAAPLIARITSIALAAREE
ILNGLSEDQIANFRTALDRMRVNLVAGRDADDA

Specific function: Transcription regulator that either activates or represses expression of target genes. Participates in transcriptional activation of pig (prodigiosin pigment) and car (carbapenem antibiotic) gene clusters [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081950, Length=139, Percent_Identity=33.8129496402878, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023071
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 21404; Mature: 21404

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVGGNRGRSACSRFFRFTLGKVNTRPGENERLESKFNLSYCGGDMSETPLGFLFFEVSR
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCEEECCCCCCCCCHHHHHHHHHH
LYRARTDRAFEQGGLGITSGEARTLIYINQHPGLRQTALAEKMSVEPMTLVASLDRLEAQ
HHHHHHHHHHHHCCCCEECCCCEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
SLVKREPDPTDRRAKRVLLTPAAAPLIARITSIALAAREEILNGLSEDQIANFRTALDRM
HHHHCCCCCCHHHHCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RVNLVAGRDADDA
HHHEEECCCCCCC
>Mature Secondary Structure
MRVGGNRGRSACSRFFRFTLGKVNTRPGENERLESKFNLSYCGGDMSETPLGFLFFEVSR
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCEEECCCCCCCCCHHHHHHHHHH
LYRARTDRAFEQGGLGITSGEARTLIYINQHPGLRQTALAEKMSVEPMTLVASLDRLEAQ
HHHHHHHHHHHHCCCCEECCCCEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
SLVKREPDPTDRRAKRVLLTPAAAPLIARITSIALAAREEILNGLSEDQIANFRTALDRM
HHHHCCCCCCHHHHCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RVNLVAGRDADDA
HHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9402023; 12519208 [H]